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Search results 1 to 100 out of 567 for Atf3

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0.053s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: ATF3 belongs to the ATF/cAMP-response element-binding protein family. It is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It serves as a hub in cellular adaptive-response and plays important roles in cancer and immunity [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
GXD Expression      
Probe: MGI:7461650
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7466119
Age: postnatal day 7
Specimen Label: Atf3
Detected: true
Specimen Num: 1
Publication
First Author: Kim WH
Year: 2011
Journal: Biochem Biophys Res Commun
Title: ATF3 inhibits PDX-1-stimulated transactivation.
Volume: 414
Issue: 4
Pages: 681-7
Publication
First Author: Hai T
Year: 2010
Journal: Gene Expr
Title: ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component?
Volume: 15
Issue: 1
Pages: 1-11
Publication  
First Author: Hai T
Year: 2011
Journal: Methods Enzymol
Title: Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network.
Volume: 490
Pages: 175-94
Publication
First Author: Iezaki T
Year: 2016
Journal: J Pathol
Title: ATF3 deficiency in chondrocytes alleviates osteoarthritis development.
Volume: 239
Issue: 4
Pages: 426-37
Publication
First Author: Yoshida T
Year: 2008
Journal: J Am Soc Nephrol
Title: ATF3 protects against renal ischemia-reperfusion injury.
Volume: 19
Issue: 2
Pages: 217-24
Publication  
First Author: Liu Y
Year: 2020
Journal: Front Cell Dev Biol
Title: ATF3 Prevents Stress-Induced Hematopoietic Stem Cell Exhaustion.
Volume: 8
Pages: 585771
Publication
First Author: Jang MK
Year: 2015
Journal: Biochem Biophys Res Commun
Title: ATF3 inhibits PPARγ-stimulated transactivation in adipocyte cells.
Volume: 456
Issue: 1
Pages: 80-5
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
Publication
First Author: Boespflug ND
Year: 2014
Journal: Blood
Title: ATF3 is a novel regulator of mouse neutrophil migration.
Volume: 123
Issue: 13
Pages: 2084-93
Publication  
First Author: Fukasawa K
Year: 2016
Journal: Sci Rep
Title: ATF3 controls proliferation of osteoclast precursor and bone remodeling.
Volume: 6
Pages: 30918
Publication
First Author: Gold ES
Year: 2012
Journal: J Exp Med
Title: ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.
Volume: 209
Issue: 4
Pages: 807-17
Publication
First Author: Wang Z
Year: 2018
Journal: Oncogene
Title: Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice.
Volume: 37
Issue: 1
Pages: 18-27
Publication
First Author: Jang MK
Year: 2014
Journal: Biochem Biophys Res Commun
Title: ATF3 represses PPARγ expression and inhibits adipocyte differentiation.
Volume: 454
Issue: 1
Pages: 58-64
Publication
First Author: Hoetzenecker W
Year: 2011
Journal: Nat Med
Title: ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression.
Volume: 18
Issue: 1
Pages: 128-34
Publication
First Author: Tsai WW
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis.
Volume: 112
Issue: 9
Pages: 2699-704
Publication
First Author: Gilchrist M
Year: 2010
Journal: Blood
Title: A key role for ATF3 in regulating mast cell survival and mediator release.
Volume: 115
Issue: 23
Pages: 4734-41
Publication
First Author: Lee YS
Year: 2013
Journal: Diabetologia
Title: Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice.
Volume: 56
Issue: 6
Pages: 1383-93
Publication
First Author: Wolford CC
Year: 2013
Journal: J Clin Invest
Title: Transcription factor ATF3 links host adaptive response to breast cancer metastasis.
Volume: 123
Issue: 7
Pages: 2893-906
Publication  
First Author: Wang A
Year: 2008
Journal: BMC Cancer
Title: The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis.
Volume: 8
Pages: 268
Publication
First Author: Kalfon R
Year: 2019
Journal: PLoS One
Title: JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function.
Volume: 14
Issue: 2
Pages: e0213081
Publication
First Author: Kim DE
Year: 2017
Journal: J Exp Med
Title: Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation.
Volume: 214
Issue: 8
Pages: 2349-2368
Publication
First Author: Vu TTM
Year: 2020
Journal: Biochemistry
Title: The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway.
Volume: 59
Issue: 30
Pages: 2796-2812
Publication
First Author: Xu Y
Year: 2021
Journal: Nat Metab
Title: Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism.
Volume: 3
Issue: 1
Pages: 59-74
Publication
First Author: Delitsikou V
Year: 2020
Journal: FASEB J
Title: Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
Volume: 34
Issue: 2
Pages: 2087-2104
Publication
First Author: Kim HB
Year: 2006
Journal: Diabetes
Title: NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes.
Volume: 55
Issue: 5
Pages: 1342-52
Publication
First Author: Wang A
Year: 2007
Journal: Mol Carcinog
Title: Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells.
Volume: 46
Issue: 6
Pages: 476-87
Publication  
First Author: Brooks AC
Year: 2014
Journal: J Mol Cell Cardiol
Title: Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning.
Volume: 76
Pages: 138-47
Publication
First Author: Kim S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Atf3 induction is a therapeutic target for obesity and metabolic diseases.
Volume: 504
Issue: 4
Pages: 903-908
Publication  
First Author: Gey M
Year: 2016
Journal: Open Biol
Title: Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury.
Volume: 6
Issue: 8
Publication
First Author: Seijffers R
Year: 2007
Journal: J Neurosci
Title: ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration.
Volume: 27
Issue: 30
Pages: 7911-20
Publication
First Author: Jang MK
Year: 2013
Journal: Biochem Biophys Res Commun
Title: ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity.
Volume: 431
Issue: 3
Pages: 421-7
Publication
First Author: Cao Y
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches.
Volume: 116
Issue: 13
Pages: 6286-6291
Publication
First Author: Zhang S
Year: 2023
Journal: Nat Commun
Title: ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression.
Volume: 14
Issue: 1
Pages: 4978
GXD Expression      
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6189821
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Atf3
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6189821
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Atf3
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6189821
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Atf3
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189821
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Atf3
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189821
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Atf3
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6189821
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Atf3
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6167889
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189821
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Atf3
Detected: false
Specimen Num: 5
Publication
First Author: Kalfon R
Year: 2017
Journal: Cardiovasc Res
Title: ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.
Volume: 113
Issue: 2
Pages: 134-146
Publication
First Author: Lu Z
Year: 2022
Journal: Cell Metab
Title: ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Volume: 34
Issue: 9
Pages: 1342-1358.e7
Publication
First Author: Turchi L
Year: 2009
Journal: Cell Death Differ
Title: ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress.
Volume: 16
Issue: 5
Pages: 728-37
Publication
First Author: Taketani K
Year: 2012
Journal: Oncogene
Title: Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.
Volume: 31
Issue: 17
Pages: 2210-21
Publication  
First Author: Bueno M
Year: 2018
Journal: Aging Cell
Title: ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis.
Volume: 17
Issue: 2
Publication
First Author: Wang H
Year: 2012
Journal: Mol Cell Biol
Title: The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor.
Volume: 32
Issue: 16
Pages: 3190-202
Publication  
First Author: Hwang S
Year: 2023
Journal: Int J Mol Sci
Title: KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression.
Volume: 24
Issue: 16
Publication
First Author: Rosenberger CM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells.
Volume: 105
Issue: 7
Pages: 2544-9
Publication
First Author: Allen-Jennings AE
Year: 2002
Journal: J Biol Chem
Title: The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression.
Volume: 277
Issue: 22
Pages: 20020-5
Publication  
First Author: Lee S
Year: 2018
Journal: Front Immunol
Title: ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection.
Volume: 9
Pages: 1954
Publication  
First Author: Jeong BC
Year: 2017
Journal: Bone
Title: ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins.
Volume: 95
Pages: 33-40
Publication
First Author: Avraham S
Year: 2019
Journal: Oncogene
Title: ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription.
Volume: 38
Issue: 20
Pages: 3812-3823
Publication
First Author: Wang Z
Year: 2015
Journal: Oncogene
Title: Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model.
Volume: 34
Issue: 38
Pages: 4975-84
Publication
First Author: Seijffers R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation.
Volume: 111
Issue: 4
Pages: 1622-7
Publication
First Author: Allen-Jennings AE
Year: 2001
Journal: J Biol Chem
Title: The roles of ATF3 in glucose homeostasis. A transgenic mouse model with liver dysfunction and defects in endocrine pancreas.
Volume: 276
Issue: 31
Pages: 29507-14
Publication
First Author: Lee YS
Year: 2014
Journal: Endocr J
Title: ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription.
Volume: 61
Issue: 1
Pages: 85-90
Publication
First Author: Darlyuk-Saadon I
Year: 2012
Journal: Biochim Biophys Acta
Title: The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.
Volume: 1819
Issue: 11-12
Pages: 1142-53
Publication
First Author: Chang YS
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis.
Volume: 114
Issue: 34
Pages: E7159-E7168
Publication
First Author: Allison MB
Year: 2018
Journal: Diabetes
Title: Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action.
Volume: 67
Issue: 6
Pages: 1093-1104
Publication
First Author: Koren L
Year: 2013
Journal: PLoS One
Title: Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy.
Volume: 8
Issue: 7
Pages: e68396
Publication  
First Author: Denk F
Year: 2015
Journal: Acta Neuropathol Commun
Title: Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis.
Volume: 3
Pages: 74
Publication  
First Author: Holland SD
Year: 2019
Journal: eNeuro
Title: An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.
Volume: 6
Issue: 2
Publication
First Author: Gilchrist M
Year: 2008
Journal: J Exp Med
Title: Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation.
Volume: 205
Issue: 10
Pages: 2349-57
Publication
First Author: Cheng YC
Year: 2021
Journal: Cell Rep
Title: Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Volume: 36
Issue: 10
Pages: 109666
Publication  
First Author: Cheng CF
Year: 2019
Journal: Commun Biol
Title: Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3.
Volume: 2
Pages: 389
Publication
First Author: Li HF
Year: 2010
Journal: J Am Soc Nephrol
Title: ATF3-mediated epigenetic regulation protects against acute kidney injury.
Volume: 21
Issue: 6
Pages: 1003-13
Publication
First Author: Okamoto Y
Year: 2001
Journal: Am J Pathol
Title: Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction.
Volume: 159
Issue: 2
Pages: 639-50
Publication  
First Author: Yan L
Year: 2021
Journal: Int J Mol Sci
Title: ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer.
Volume: 22
Issue: 5
Publication
First Author: Hartman MG
Year: 2004
Journal: Mol Cell Biol
Title: Role for activating transcription factor 3 in stress-induced beta-cell apoptosis.
Volume: 24
Issue: 13
Pages: 5721-32
Publication  
First Author: Wang L
Year: 2012
Journal: Neuroscience
Title: Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice.
Volume: 220
Pages: 100-8
Publication
First Author: Zmuda EJ
Year: 2010
Journal: Mol Endocrinol
Title: The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.
Volume: 24
Issue: 7
Pages: 1423-33
Publication
First Author: Duprez J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets.
Volume: 415
Issue: 2
Pages: 294-9
Publication  
First Author: Pai CS
Year: 2018
Journal: Front Mol Neurosci
Title: The Activating Transcription Factor 3 (Atf3) Homozygous Knockout Mice Exhibit Enhanced Conditioned Fear and Down Regulation of Hippocampal GELSOLIN.
Volume: 11
Pages: 37
Publication
First Author: Fernández-Verdejo R
Year: 2017
Journal: FASEB J
Title: Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal muscle after exercise and facilitates molecular adaptation to endurance training.
Volume: 31
Issue: 2
Pages: 840-851
Publication
First Author: Whitmore MM
Year: 2007
Journal: J Immunol
Title: Negative regulation of TLR-signaling pathways by activating transcription factor-3.
Volume: 179
Issue: 6
Pages: 3622-30
Publication
First Author: Fernández-Verdejo R
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Activating transcription factor 3 regulates chemokine expression in contracting C2C12 myotubes and in mouse skeletal muscle after eccentric exercise.
Volume: 492
Issue: 2
Pages: 249-254
Publication
First Author: Zhou H
Year: 2011
Journal: PLoS One
Title: Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload.
Volume: 6
Issue: 10
Pages: e26744
Publication
First Author: Turchi L
Year: 2008
Journal: Cell Death Differ
Title: Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway.
Volume: 15
Issue: 9
Pages: 1472-80
Publication  
First Author: Wu YL
Year: 2022
Journal: Cells
Title: Salvia miltiorrhiza Extract and Individual Synthesized Component Derivatives Induce Activating-Transcription-Factor-3-Mediated Anti-Obesity Effects and Attenuate Obesity-Induced Metabolic Disorder by Suppressing C/EBPα in High-Fat-Induced Obese Mice.
Volume: 11
Issue: 6
Publication
First Author: Brooks AC
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Induction of activating transcription factor 3 limits survival following infarct-induced heart failure in mice.
Volume: 309
Issue: 8
Pages: H1326-35
Publication
First Author: Liu B
Year: 2006
Journal: Horm Res
Title: Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation.
Volume: 65
Issue: 5
Pages: 217-22
Publication
First Author: Spassov S
Year: 2014
Journal: PLoS One
Title: Genetic targets of hydrogen sulfide in ventilator-induced lung injury--a microarray study.
Volume: 9
Issue: 7
Pages: e102401
Publication
First Author: Cao Y
Year: 2020
Journal: J Immunol
Title: Critical Role of Intestinal Microbiota in ATF3-Mediated Gut Immune Homeostasis.
Volume: 205
Issue: 3
Pages: 842-852
Publication
First Author: Deviatiiarov R
Year: 2021
Journal: Commun Biol
Title: Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle.
Volume: 4
Issue: 1
Pages: 1290
Publication
First Author: Qi L
Year: 2009
Journal: Cell Metab
Title: Adipocyte CREB promotes insulin resistance in obesity.
Volume: 9
Issue: 3
Pages: 277-86