|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 926 for Atf4

<< First    < Previous  |  Next >    Last >>
0.02s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
468 | ATF4
Type: gene
Organism: human
•
•
•
•
•
Gene
448005 | atf4
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
79255 | Atf4
Type: gene
Organism: rat
•
•
•
•
•
Gene
744513 | ATF4
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
474503 | ATF4
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
509107 | ATF4
Type: gene
Organism: cattle
•
•
•
•
•
Gene
395693 | ATF4
Type: gene
Organism: chicken
•
•
•
•
•
Gene
703965 | ATF4
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Domain
IPR029811 | ATF4
Type: Family
Description: ATF4 belongs to the ATF/cAMP-response element-binding protein family. It is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters [, ]. It plays a crucial role in the adaptation to stresses by regulating the transcription of many genes [].
•
•
•
•
•
Protein Coding Gene
MGI:88096 | Atf4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5000865
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3643723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5448215
Age: embryonic day 15.5
Image: 4 Atf4
Note: Expression was detected in cortical kidney mesenchyme.
Specimen Label: 4 Atf4
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
8506317 | J:34756
First Author: Vallejo M
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.
Volume: 90
Issue: 10
Pages: 4679-83
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5811605
Assay Type: Western blot
Annotation Date: 2016-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:5811619
Age: embryonic day 12.0
Image: S4
Specimen Label: IP ATF4
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5811601
Assay Type: Western blot
Annotation Date: 2016-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:5811620
Age: embryonic day 12.0
Image: S4
Specimen Label: IP ATF4
Detected: true
Specimen Num: 2
•
•
•
•
•
Protein
Q3TZI8
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
•
•
•
•
•
Protein
A0A2R8VI82
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
•
•
•
•
•
Publication
23804767 | -
First Author: B'chir W
Year: 2013
Journal: Nucleic Acids Res
Title: The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression.
Volume: 41
Issue: 16
Pages: 7683-99
•
•
•
•
•
Publication
12202230 | -
First Author: Gachon F
Year: 2002
Journal: Virology
Title: Activation of HTLV-I transcription in the presence of Tax is independent of the acetylation of CREB-2 (ATF-4).
Volume: 299
Issue: 2
Pages: 271-8
•
•
•
•
•
Publication
23223004 | J:194857
First Author: Wang X
Year: 2013
Journal: Nat Med
Title: miR-214 targets ATF4 to inhibit bone formation.
Volume: 19
Issue: 1
Pages: 93-100
•
•
•
•
•
Publication
10096021 | J:56007
First Author: Tanaka T
Year: 1998
Journal: Genes Cells
Title: Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres.
Volume: 3
Issue: 12
Pages: 801-10
•
•
•
•
•
Protein
Q06507
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
•
•
•
•
•
Protein
Q794G7
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
•
•
•
•
•
Protein
Q3U2J1
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
•
•
•
•
•
Protein
Q61328
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
•
•
•
•
•
Protein
Q8CF69
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
•
•
•
•
•
Publication
21644928 | J:177892
First Author: Li H
Year: 2011
Journal: Biochem J
Title: ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis.
Volume: 438
Issue: 2
Pages: 283-9
•
•
•
•
•
Publication
35489203 | J:333666
 
First Author: Sobajima M
Year: 2022
Journal: Biochem Biophys Res Commun
Title: The multifaceted role of ATF4 in regulating glucose-stimulated insulin secretion.
Volume: 611
Pages: 165-171
•
•
•
•
•
Publication
19690063 | J:154380
First Author: Seo J
Year: 2009
Journal: Diabetes
Title: Atf4 regulates obesity, glucose homeostasis, and energy expenditure.
Volume: 58
Issue: 11
Pages: 2565-73
•
•
•
•
•
Publication
22190639 | J:179733
First Author: Wang W
Year: 2012
Journal: Development
Title: Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh.
Volume: 139
Issue: 3
Pages: 601-11
•
•
•
•
•
Publication
23888053 | J:203538
First Author: Xiao G
Year: 2013
Journal: J Biol Chem
Title: ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice.
Volume: 288
Issue: 35
Pages: 25350-61
•
•
•
•
•
Publication
31433867 | J:294678
First Author: Zhang Y
Year: 2019
Journal: J Bone Miner Res
Title: Hop2 Interacts with ATF4 to Promote Osteoblast Differentiation.
Volume: 34
Issue: 12
Pages: 2287-2300
•
•
•
•
•
Publication
12749859 | J:83554
First Author: Ord D
Year: 2003
Journal: Exp Cell Res
Title: Mouse NIPK interacts with ATF4 and affects its transcriptional activity.
Volume: 286
Issue: 2
Pages: 308-20
•
•
•
•
•
Publication
35574856 | J:341480
First Author: Wang X
Year: 2022
Journal: Circ Res
Title: ATF4 Protects the Heart From Failure by Antagonizing Oxidative Stress.
Volume: 131
Issue: 1
Pages: 91-105
•
•
•
•
•
Publication
29742431 | J:270637
First Author: Yang X
Year: 2018
Journal: Cell Rep
Title: ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming.
Volume: 23
Issue: 6
Pages: 1754-1766
•
•
•
•
•
Publication
34551310 | J:321449
First Author: Paulo E
Year: 2021
Journal: Cell Rep
Title: Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism.
Volume: 36
Issue: 12
Pages: 109742
•
•
•
•
•
Publication
30709400 | J:277711
First Author: Yue Y
Year: 2019
Journal: J Neuroinflammation
Title: Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE.
Volume: 16
Issue: 1
Pages: 23
•
•
•
•
•
Publication
33658516 | J:304927
First Author: Xie MX
Year: 2021
Journal: Nat Commun
Title: ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking.
Volume: 12
Issue: 1
Pages: 1401
•
•
•
•
•
Publication
37014538 | J:339561
   
First Author: Miller MJ
Year: 2023
Journal: Geroscience
Title: The transcription regulator ATF4 is a mediator of skeletal muscle aging.
Pages: 1-19
•
•
•
•
•
Publication
31263264 | J:332535
First Author: Tameire F
Year: 2019
Journal: Nat Cell Biol
Title: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
Volume: 21
Issue: 7
Pages: 889-899
•
•
•
•
•
Publication
25865882 | J:228389
First Author: Pasini S
Year: 2015
Journal: Cell Rep
Title: Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory.
Volume: 11
Issue: 2
Pages: 183-91
•
•
•
•
•
Publication
22498744 | J:185147
First Author: Suragani RN
Year: 2012
Journal: Blood
Title: Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis.
Volume: 119
Issue: 22
Pages: 5276-84
•
•
•
•
•
Publication
36996941 | J:360687
First Author: He F
Year: 2023
Journal: J Hepatol
Title: ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis.
Volume: 79
Issue: 2
Pages: 362-377
•
•
•
•
•
Publication
23874395 | J:204414
First Author: Matus S
Year: 2013
Journal: PLoS One
Title: Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.
Volume: 8
Issue: 7
Pages: e66672
•
•
•
•
•
Publication
22102693 | J:181160
First Author: Horiguchi M
Year: 2012
Journal: Cancer Res
Title: Stress-regulated transcription factor ATF4 promotes neoplastic transformation by suppressing expression of the INK4a/ARF cell senescence factors.
Volume: 72
Issue: 2
Pages: 395-401
•
•
•
•
•
Publication
19906842 | J:154906
First Author: Wang W
Year: 2009
Journal: Development
Title: Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.
Volume: 136
Issue: 24
Pages: 4143-53
•
•
•
•
•
Publication
33154371 | J:297873
First Author: Kasetti RB
Year: 2020
Journal: Nat Commun
Title: ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load.
Volume: 11
Issue: 1
Pages: 5594
•
•
•
•
•
Publication
22813743 | J:196023
First Author: Trinh MA
Year: 2012
Journal: Cell Rep
Title: Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.
Volume: 1
Issue: 6
Pages: 676-88
•
•
•
•
•
Publication
27452504 | J:250926
First Author: Chen H
Year: 2016
Journal: Biochim Biophys Acta
Title: ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation.
Volume: 1859
Issue: 11
Pages: 1459-1469
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189822
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Atf4
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189822
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Atf4
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189822
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Atf4
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189822
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Atf4
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189822
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Atf4
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189822
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Atf4
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167890
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189822
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Atf4
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
18458112 | J:136222
First Author: Lange PS
Year: 2008
Journal: J Exp Med
Title: ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo.
Volume: 205
Issue: 5
Pages: 1227-42
•
•
•
•
•
Publication
28566324 | J:247277
First Author: Quirós PM
Year: 2017
Journal: J Cell Biol
Title: Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.
Volume: 216
Issue: 7
Pages: 2027-2045
•
•
•
•
•
Publication
23942974 | J:214271
First Author: Wang X
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Modulation of angiogenesis by genetic manipulation of ATF4 in mouse model of oxygen-induced retinopathy [corrected].
Volume: 54
Issue: 9
Pages: 5995-6002
•
•
•
•
•
Publication
22980225 | J:249904
First Author: Wang C
Year: 2013
Journal: Metabolism
Title: Effects of ATF4 on PGC1α expression in brown adipose tissue and metabolic responses to cold stress.
Volume: 62
Issue: 2
Pages: 282-9
•
•
•
•
•
Publication
27405764 | J:236152
First Author: Li K
Year: 2016
Journal: J Biol Chem
Title: Liver-specific Gene Inactivation of the Transcription Factor ATF4 Alleviates Alcoholic Liver Steatosis in Mice.
Volume: 291
Issue: 35
Pages: 18536-46
•
•
•
•
•
Publication
22298775 | J:183276
First Author: Kode A
Year: 2012
Journal: J Biol Chem
Title: FoxO1 protein cooperates with ATF4 protein in osteoblasts to control glucose homeostasis.
Volume: 287
Issue: 12
Pages: 8757-68
•
•
•
•
•
Publication
19726872 | J:152695
First Author: Yoshizawa T
Year: 2009
Journal: J Clin Invest
Title: The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts.
Volume: 119
Issue: 9
Pages: 2807-17
•
•
•
•
•
Publication
24373582 | J:329844
First Author: Wang C
Year: 2014
Journal: J Cell Mol Med
Title: ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression.
Volume: 18
Issue: 1
Pages: 80-90
•
•
•
•
•
Publication
17726049 | J:172182
First Author: Chérasse Y
Year: 2007
Journal: Nucleic Acids Res
Title: The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP.
Volume: 35
Issue: 17
Pages: 5954-65
•
•
•
•
•
Publication
27993927 | J:247015
First Author: Deng J
Year: 2017
Journal: Diabetes
Title: Deletion of ATF4 in AgRP Neurons Promotes Fat Loss Mainly via Increasing Energy Expenditure.
Volume: 66
Issue: 3
Pages: 640-650
•
•
•
•
•
Publication
38238383 | J:346020
First Author: Bjorkman SH
Year: 2024
Journal: Sci Rep
Title: ATF4 expression in thermogenic adipocytes is required for cold-induced thermogenesis in mice via FGF21-independent mechanisms.
Volume: 14
Issue: 1
Pages: 1563
•
•
•
•
•
Publication
24691093 | J:328967
First Author: Li W
Year: 2015
Journal: J Gerontol A Biol Sci Med Sci
Title: Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice.
Volume: 70
Issue: 3
Pages: 263-72
•
•
•
•
•
Publication
19232401 | J:148804
First Author: Yu VW
Year: 2009
Journal: Gene Expr Patterns
Title: FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes.
Volume: 9
Issue: 5
Pages: 335-40
•
•
•
•
•
Publication
34303878 | J:330001
 
First Author: Byles V
Year: 2021
Journal: Mol Metab
Title: Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.
Volume: 53
Pages: 101309
•
•
•
•
•
Publication
24895282 | J:215331
First Author: Fox DK
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization.
Volume: 307
Issue: 3
Pages: E245-61
•
•
•
•
•
Publication
17141628 | J:129752
First Author: Elefteriou F
Year: 2006
Journal: Cell Metab
Title: ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.
Volume: 4
Issue: 6
Pages: 441-51
•
•
•
•
•
Publication
12925279 | J:85101
First Author: Chen A
Year: 2003
Journal: Neuron
Title: Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins.
Volume: 39
Issue: 4
Pages: 655-69
•
•
•
•
•
Publication
22974638 | J:193213
First Author: Ambivero CT
Year: 2012
Journal: Biochim Biophys Acta
Title: ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
Volume: 1823
Issue: 12
Pages: 2149-56
•
•
•
•
•
Publication
23580573 | J:197041
First Author: Horiguchi M
Year: 2013
Journal: Cancer Res
Title: Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells.
Volume: 73
Issue: 8
Pages: 2639-49
•
•
•
•
•
Publication
15109498 | J:89403
First Author: Yang X
Year: 2004
Journal: Cell
Title: ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome.
Volume: 117
Issue: 3
Pages: 387-98
•
•
•
•
•
Publication
23649506 | J:244618
First Author: Zhu K
Year: 2013
Journal: J Bone Miner Res
Title: ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
Volume: 28
Issue: 9
Pages: 1870-1884
•
•
•
•
•
Publication
37998373 | J:342871
 
First Author: Xiang J
Year: 2023
Journal: Cells
Title: ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment.
Volume: 12
Issue: 22
•
•
•
•
•
Publication
26384355 | J:230076
First Author: Zhao Y
Year: 2015
Journal: Blood
Title: ATF4 plays a pivotal role in the development of functional hematopoietic stem cells in mouse fetal liver.
Volume: 126
Issue: 21
Pages: 2383-91
•
•
•
•
•
Publication
20592469 | J:163777
First Author: Liew CW
Year: 2010
Journal: J Clin Invest
Title: The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.
Volume: 120
Issue: 8
Pages: 2876-88
•
•
•
•
•
Publication
30452920 | J:294310
First Author: Hu X
Year: 2019
Journal: Gastroenterology
Title: ATF4 Deficiency Promotes Intestinal Inflammation in Mice by Reducing Uptake of Glutamine and Expression of Antimicrobial Peptides.
Volume: 156
Issue: 4
Pages: 1098-1111
•
•
•
•
•
Publication
37280306 | J:341026
First Author: Gao Y
Year: 2023
Journal: Sci Rep
Title: Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3.
Volume: 13
Issue: 1
Pages: 9193
•
•
•
•
•
Publication
26960794 | J:312639
First Author: Fusakio ME
Year: 2016
Journal: Mol Biol Cell
Title: Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.
Volume: 27
Issue: 9
Pages: 1536-51
•
•
•
•
•
Publication
35061305 | J:329544
First Author: Oyabu M
Year: 2022
Journal: FASEB J
Title: FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting.
Volume: 36
Issue: 2
Pages: e22152
•
•
•
•
•
Publication
15013631 | J:88780
First Author: Ritter B
Year: 2004
Journal: Brain Res Dev Brain Res
Title: The GABA(B) receptor subunits R1 and R2 interact differentially with the activation transcription factor ATF4 in mouse brain during the postnatal development.
Volume: 149
Issue: 1
Pages: 73-7
•
•
•
•
•
Publication
27144303 | J:249071
First Author: Bhootada Y
Year: 2016
Journal: PLoS One
Title: Limited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa.
Volume: 11
Issue: 5
Pages: e0154779
•
•
•
•
•
Publication
18955481 | J:144074
First Author: Song H
Year: 2008
Journal: J Biol Chem
Title: Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.
Volume: 283
Issue: 52
Pages: 36687-97
•
•
•
•
•
Publication
12871976 | J:217287
First Author: Luo S
Year: 2003
Journal: J Biol Chem
Title: Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements.
Volume: 278
Issue: 39
Pages: 37375-85
•
•
•
•
•
Publication
11806972 | J:74479
First Author: Masuoka HC
Year: 2002
Journal: Blood
Title: Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice.
Volume: 99
Issue: 3
Pages: 736-45
•
•
•
•
•
Publication
15911876 | J:100180
First Author: Yu VW
Year: 2005
Journal: J Cell Biol
Title: FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice.
Volume: 169
Issue: 4
Pages: 591-601
•
•
•
•
•
Publication
35977507 | J:330811
First Author: MacArthur MR
Year: 2022
Journal: Cell Rep
Title: Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
Volume: 40
Issue: 7
Pages: 111187
•
•
•
•
•
Publication
19851510 | J:154038
First Author: Yu S
Year: 2009
Journal: PLoS One
Title: Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone.
Volume: 4
Issue: 10
Pages: e7583
•
•
•
•
•
Publication
34358431 | J:309733
First Author: Fan Z
Year: 2021
Journal: Cell Metab
Title: Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells.
Volume: 33
Issue: 9
Pages: 1793-1807.e9
•
•
•
•
•
Publication
19059405 | J:142693
First Author: Jin HO
Year: 2009
Journal: FEBS Lett
Title: SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
Volume: 583
Issue: 1
Pages: 123-7
•
•
•
•
•
Publication
33443099 | J:314593
 
First Author: Mendes A
Year: 2021
Journal: Life Sci Alliance
Title: Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4.
Volume: 4
Issue: 2
•
•
•
•
•
Publication
37453419 | J:353968
First Author: Kumar A
Year: 2023
Journal: Neuron
Title: 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience.
Volume: 111
Issue: 18
Pages: 2831-2846.e10
•
•
•
•
•
Publication
30674717 | J:278405
 
First Author: Stone S
Year: 2019
Journal: JCI Insight
Title: Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis.
Volume: 4
Issue: 2
•
•
•
•
•
Publication
25857264 | J:259334
First Author: D'Aniello C
Year: 2015
Journal: Cell Death Differ
Title: A novel autoregulatory loop between the Gcn2-Atf4 pathway and (L)-Proline [corrected] metabolism controls stem cell identity.
Volume: 22
Issue: 7
Pages: 1094-105
•
•
•
•
•
Publication
23624402 | J:198492
First Author: Han J
Year: 2013
Journal: Nat Cell Biol
Title: ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Volume: 15
Issue: 5
Pages: 481-90
•
•
•
•
•
Publication
27812542 | J:237331
First Author: Masuda M
Year: 2016
Journal: JCI Insight
Title: Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells.
Volume: 1
Issue: 18
Pages: e88646
•
•
•
•
•
Publication
33944779 | J:327582
   
First Author: Pereira RO
Year: 2021
Journal: Elife
Title: OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21.
Volume: 10
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom