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Search results 1 to 100 out of 475 for Atf6

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Type Details Score
Gene
22926 | ATF6
Type: gene
Organism: human
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Gene
530610 | ATF6
Type: gene
Organism: cattle
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Gene
558071 | atf6
Type: gene
Organism: zebrafish
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Gene
720056 | ATF6
Type: gene
Organism: macaque, rhesus
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Gene
100498199 | atf6
Type: gene
Organism: frog, western clawed
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Gene
304962 | Atf6
Type: gene
Organism: rat
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Gene
488660 | ATF6
Type: gene
Organism: dog, domestic
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Gene
457461 | ATF6
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1926157 | Atf6
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
102724329 | ATF6-DT
Type: gene
Organism: human
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Publication
34904262 | J:334705
First Author: Yu R
Year: 2022
Journal: Andrologia
Title: ATF6 deficiency damages the development of spermatogenesis in male Atf6 knockout mice.
Volume: 54
Issue: 3
Pages: e14350
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Publication
36313623 | J:331556
 
First Author: Li X
Year: 2022
Journal: Front Cell Neurosci
Title: Beneficial effects of neuronal ATF6 activation in permanent ischemic stroke.
Volume: 16
Pages: 1016391
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Publication
22102412 | J:321032
First Author: Jang WG
Year: 2012
Journal: J Biol Chem
Title: BMP2 protein regulates osteocalcin expression via Runx2-mediated Atf6 gene transcription.
Volume: 287
Issue: 2
Pages: 905-15
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Publication
24035931 | J:203910
First Author: Zhang WG
Year: 2013
Journal: Gene
Title: Mmu-miR-702 functions as an anti-apoptotic mirtron by mediating ATF6 inhibition in mice.
Volume: 531
Issue: 2
Pages: 235-42
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Publication
31506423 | J:328914
First Author: Zhou L
Year: 2019
Journal: Cell Death Dis
Title: ATF6 regulates the development of chronic pancreatitis by inducing p53-mediated apoptosis.
Volume: 10
Issue: 9
Pages: 662
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Publication
26029869 | J:231780
First Author: Kohl S
Year: 2015
Journal: Nat Genet
Title: Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
Volume: 47
Issue: 7
Pages: 757-65
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Publication
30643122 | J:270190
First Author: Blackwood EA
Year: 2019
Journal: Nat Commun
Title: Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis.
Volume: 10
Issue: 1
Pages: 187
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Publication
30582446 | J:292335
First Author: Blackwood EA
Year: 2019
Journal: Circ Res
Title: ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
Volume: 124
Issue: 1
Pages: 79-93
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Publication
30236984 | J:272989
First Author: Sun X
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway.
Volume: 505
Issue: 1
Pages: 45-50
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Publication
26374329 | J:317048
 
First Author: Xiong Z
Year: 2015
Journal: J Orthop Surg Res
Title: Transmission of ER stress response by ATF6 promotes endochondral bone growth.
Volume: 10
Pages: 141
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Publication
25492867 | J:219357
First Author: Elimam H
Year: 2015
Journal: J Biol Chem
Title: Calcium-independent phospholipase A2γ enhances activation of the ATF6 transcription factor during endoplasmic reticulum stress.
Volume: 290
Issue: 5
Pages: 3009-20
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Publication
27217380 | J:323043
First Author: Yu Z
Year: 2017
Journal: J Cereb Blood Flow Metab
Title: Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome.
Volume: 37
Issue: 3
Pages: 1069-1079
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Publication
32788214 | J:298919
First Author: Sharma RB
Year: 2020
Journal: J Biol Chem
Title: Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.
Volume: 295
Issue: 41
Pages: 14164-14177
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Publication
32724472 | J:328915
First Author: Tan JH
Year: 2020
Journal: Theranostics
Title: ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis.
Volume: 10
Issue: 18
Pages: 8298-8314
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Publication
27207533 | J:246318
First Author: Chen X
Year: 2016
Journal: Diabetes
Title: Hepatic ATF6 Increases Fatty Acid Oxidation to Attenuate Hepatic Steatosis in Mice Through Peroxisome Proliferator-Activated Receptor α.
Volume: 65
Issue: 7
Pages: 1904-15
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Publication
27932512 | J:262018
First Author: Jin JK
Year: 2017
Journal: Circ Res
Title: ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart.
Volume: 120
Issue: 5
Pages: 862-875
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Publication
24746698 | J:213604
First Author: Karali E
Year: 2014
Journal: Mol Cell
Title: VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress.
Volume: 54
Issue: 4
Pages: 559-72
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Publication
34381136 | J:320973
First Author: Lee EJ
Year: 2021
Journal: Sci Rep
Title: ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model.
Volume: 11
Issue: 1
Pages: 16356
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Publication
21917591 | J:273445
First Author: Teske BF
Year: 2011
Journal: Mol Biol Cell
Title: The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
Volume: 22
Issue: 22
Pages: 4390-405
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Publication
25135476 | J:224336
First Author: Gade P
Year: 2014
Journal: Mol Cell Biol
Title: Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.
Volume: 34
Issue: 21
Pages: 4033-48
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Publication
23395094 | J:195775
First Author: Liu L
Year: 2013
Journal: Am J Pathol
Title: Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.
Volume: 182
Issue: 4
Pages: 1412-24
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Protein
Q811K9
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: true
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Publication
32085622 | J:297791
 
First Author: Stauffer WT
Year: 2020
Journal: Int J Mol Sci
Title: The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts.
Volume: 21
Issue: 4
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Publication
22699507 | J:185579
First Author: Gade P
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy.
Volume: 109
Issue: 26
Pages: 10316-21
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Publication
26842780 | J:321006
First Author: Saraswat Ohri S
Year: 2018
Journal: J Neurotrauma
Title: Activating Transcription Factor-6α Deletion Modulates the Endoplasmic Reticulum Stress Response after Spinal Cord Injury but Does Not Affect Locomotor Recovery.
Volume: 35
Issue: 3
Pages: 486-491
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Publication
26527399 | J:247203
First Author: Guo F
Year: 2016
Journal: J Cell Sci
Title: ATF6a, a Runx2-activable transcription factor, is a new regulator of chondrocyte hypertrophy.
Volume: 129
Issue: 4
Pages: 717-28
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Publication
17765680 | J:145116
First Author: Yamamoto K
Year: 2007
Journal: Dev Cell
Title: Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.
Volume: 13
Issue: 3
Pages: 365-76
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Publication
35609415 | J:340824
 
First Author: Zhang JY
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Activating transcription factor 6 regulates cystathionine to increase autophagy and restore memory in Alzheimer' s disease model mice.
Volume: 615
Pages: 109-115
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Publication
19940266 | J:170056
First Author: Belmont PJ
Year: 2010
Journal: Circ Res
Title: Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart.
Volume: 106
Issue: 2
Pages: 307-16
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Publication
24225943 | J:213542
First Author: Engin F
Year: 2013
Journal: Sci Transl Med
Title: Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.
Volume: 5
Issue: 211
Pages: 211ra156
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Publication
26752648 | J:231158
First Author: Naranjo JR
Year: 2016
Journal: J Clin Invest
Title: Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease.
Volume: 126
Issue: 2
Pages: 627-38
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Publication
29523177 | J:271970
First Author: López-Hurtado A
Year: 2018
Journal: Mol Brain
Title: Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington's disease.
Volume: 11
Issue: 1
Pages: 13
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Publication
25754093 | J:221890
 
First Author: Madhusudhan T
Year: 2015
Journal: Nat Commun
Title: Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.
Volume: 6
Pages: 6496
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Publication
21385877 | J:171119
First Author: Peña J
Year: 2011
Journal: J Biol Chem
Title: Dengue virus modulates the unfolded protein response in a time-dependent manner.
Volume: 286
Issue: 16
Pages: 14226-36
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Publication
27239042 | J:238165
First Author: Ozcan L
Year: 2016
Journal: Cell Rep
Title: Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.
Volume: 15
Issue: 10
Pages: 2214-2225
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Publication
14559994 | J:215656
First Author: Lee AH
Year: 2003
Journal: Mol Cell Biol
Title: XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response.
Volume: 23
Issue: 21
Pages: 7448-59
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Publication
30765833 | J:275536
First Author: Correll RN
Year: 2019
Journal: Sci Rep
Title: Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart.
Volume: 9
Issue: 1
Pages: 2059
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Publication
28747345 | J:251260
First Author: Dang J
Year: 2017
Journal: J Immunol
Title: ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.
Volume: 199
Issue: 5
Pages: 1647-1659
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Publication
23724040 | J:200711
First Author: Benosman S
Year: 2013
Journal: PLoS One
Title: Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling.
Volume: 8
Issue: 5
Pages: e64256
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Publication
29522813 | J:271184
 
First Author: Forouhan M
Year: 2018
Journal: Matrix Biol
Title: Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.
Volume: 70
Pages: 50-71
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Publication
37025177 | J:345239
 
First Author: Gutiérrez-Ballesteros F
Year: 2023
Journal: Front Cell Dev Biol
Title: Normal tissue homeostasis and impairment of selective inflammatory responses in dendritic cells deficient for ATF6α.
Volume: 11
Pages: 1089728
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Publication
34228641 | J:310086
 
First Author: Tcyganov EN
Year: 2021
Journal: J Clin Invest
Title: Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer.
Volume: 131
Issue: 16
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Publication
32167239 | J:306913
First Author: Kwon MY
Year: 2020
Journal: FEBS J
Title: Nucleotide-binding oligomerization domain protein 2 deficiency enhances CHOP expression and plaque necrosis in advanced atherosclerotic lesions.
Volume: 287
Issue: 10
Pages: 2055-2069
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Publication
18319259 | J:137088
First Author: Belmont PJ
Year: 2008
Journal: J Biol Chem
Title: Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene.
Volume: 283
Issue: 20
Pages: 14012-21
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Publication
24519940 | J:212438
First Author: Afrazi A
Year: 2014
Journal: J Biol Chem
Title: Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
Volume: 289
Issue: 14
Pages: 9584-99
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Publication
16452489 | J:111577
First Author: Mao C
Year: 2006
Journal: J Biol Chem
Title: In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4.
Volume: 281
Issue: 13
Pages: 8877-87
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Publication
24339898 | J:211163
First Author: Scaiewicz V
Year: 2013
Journal: PLoS One
Title: CCAAT/enhancer-binding protein homologous (CHOP) protein promotes carcinogenesis in the DEN-induced hepatocellular carcinoma model.
Volume: 8
Issue: 12
Pages: e81065
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Publication
32758541 | J:294896
 
First Author: Aryal YP
Year: 2020
Journal: Gene Expr Patterns
Title: Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development.
Volume: 37
Pages: 119130
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Publication
30685387 | J:286157
 
First Author: Zheng C
Year: 2019
Journal: EBioMedicine
Title: Suppressing UPR-dependent overactivation of FGFR3 signaling ameliorates SLC26A2-deficient chondrodysplasias.
Volume: 40
Pages: 695-709
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Protein Coding Gene
MGP_CAROLIEiJ_G0014844 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016679 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016674 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1926157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017135 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016602 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028081 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015648 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29436030 | J:262959
First Author: Stone S
Year: 2018
Journal: Glia
Title: Activating transcription factor 6α deficiency exacerbates oligodendrocyte death and myelin damage in immune-mediated demyelinating diseases.
Volume: 66
Issue: 7
Pages: 1331-1345
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Publication
23112876 | J:192297
First Author: Hashida K
Year: 2012
Journal: PLoS One
Title: ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's disease.
Volume: 7
Issue: 10
Pages: e47950
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Publication
25351847 | J:218276
First Author: Yoshikawa A
Year: 2015
Journal: J Neurochem
Title: Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice.
Volume: 132
Issue: 3
Pages: 342-53
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Publication
27333444 | J:237956
First Author: Ta HM
Year: 2016
Journal: J Neurochem
Title: Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis.
Volume: 139
Issue: 6
Pages: 1124-1137
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Publication
26724566 | J:321031
 
First Author: Kezuka D
Year: 2016
Journal: Neurochem Int
Title: Deletion of Atf6α enhances kainate-induced neuronal death in mice.
Volume: 92
Pages: 67-74
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Publication
22555069 | J:188171
First Author: Aragon IV
Year: 2012
Journal: Mol Immunol
Title: The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.
Volume: 51
Issue: 3-4
Pages: 347-55
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Publication
28958904 | J:321008
First Author: Unno H
Year: 2018
Journal: J Allergy Clin Immunol
Title: Activating transcription factor 6α (ATF6α) regulates airway hyperreactivity, smooth muscle proliferation, and contractility.
Volume: 141
Issue: 1
Pages: 439-442.e4
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Publication
24069029 | J:320891
 
First Author: Arensdorf AM
Year: 2013
Journal: Front Genet
Title: Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network.
Volume: 4
Pages: 188
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Publication
28564599 | J:254336
First Author: DeZwaan-McCabe D
Year: 2017
Journal: Cell Rep
Title: ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis.
Volume: 19
Issue: 9
Pages: 1794-1806
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Publication
27717400 | J:316095
First Author: Xiong Y
Year: 2016
Journal: Reprod Biol Endocrinol
Title: Expression and regulation of ATF6α in the mouse uterus during embryo implantation.
Volume: 14
Issue: 1
Pages: 65
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GXD Expression
GXD Expression
   
Probe: MGI:3655470
Assay Type: RT-PCR
Annotation Date: 2006-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:3655478
Age: embryonic day 11.5
Image: 3
Specimen Label: He
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3655470
Assay Type: RT-PCR
Annotation Date: 2006-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:3655478
Age: embryonic day 11.5
Image: 3
Specimen Label: Br
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3655470
Assay Type: RT-PCR
Annotation Date: 2006-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618419
Stage: TS19
Assay Id: MGI:3655478
Age: embryonic day 11.5
Image: 3
Specimen Label: So
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:5301164
Age: embryonic day 14.5
Image: 7
Specimen Label: E14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783823
Stage: TS23
Assay Id: MGI:5301164
Age: embryonic day 15.5
Image: 7
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Stage: TS24
Assay Id: MGI:5301164
Age: embryonic day 16.5
Image: 7
Specimen Label: E16.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Stage: TS25
Assay Id: MGI:5301164
Age: embryonic day 17.5
Image: 7
Specimen Label: E17.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783826
Stage: TS26
Assay Id: MGI:5301164
Age: embryonic day 18.5
Image: 7
Specimen Label: E18.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:5301164
Age: postnatal day 3
Image: 7
Specimen Label: P3
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5300965
Assay Type: Western blot
Annotation Date: 2012-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:5301164
Age: postnatal day 10
Image: 7
Specimen Label: P10
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6423162
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423469
Age: postnatal month 1
Image: S7
Specimen Label: Con
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6423162
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423469
Age: postnatal month 1
Image: S7
Specimen Label: Con
Detected: true
Specimen Num: 2
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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