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Search results 1 to 97 out of 97 for Atg4a

0.019s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
115201 | ATG4A
Type: gene
Organism: human
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Gene
549373 | atg4a
Type: gene
Organism: frog, western clawed
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Gene
678769 | Atg4a
Type: gene
Organism: rat
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Gene
473725 | ATG4A
Type: gene
Organism: chimpanzee
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Gene
481015 | ATG4A
Type: gene
Organism: dog, domestic
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Gene
408003 | ATG4A
Type: gene
Organism: cattle
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Gene
772074 | ATG4A
Type: gene
Organism: chicken
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Gene
554140 | atg4a
Type: gene
Organism: zebrafish
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Gene
703367 | ATG4A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2147903 | Atg4a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033474 | ATG4A
Type: Family
Description: Autophagin-2 (ATG4A, MEROPS identifier C54.002) is a cysteine endopeptidase required for autophagy, an intracellular degradation system found only in eukaryotes [, ]. Once induced, double membrane-bound vesicles called autophagosomes engulf cytoplasm, even whole organelles and invading bacteria, and deliver them to the lysosome for degradation. Autophagins cleave proteins required for autophagosome development, such as gamma-aminobutyric acid receptor-associated protein (GABARAP), gamma-aminobutyric acid receptor-associated protein-like 2 (GATE-16), and microtubule-associated protein light chain 3 (LC3). GABARAP and GATE-16 seem to be better substrates than LC3B for ATG4A [, , ].
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Protein
Q8C9S8
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Publication
12446702 | J:81439
First Author: Mariño G
Year: 2003
Journal: J Biol Chem
Title: Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.
Volume: 278
Issue: 6
Pages: 3671-8
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Publication
21177865 | -
First Author: Li M
Year: 2011
Journal: J Biol Chem
Title: Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates.
Volume: 286
Issue: 9
Pages: 7327-38
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Publication
15169837 | -
First Author: Kabeya Y
Year: 2004
Journal: J Cell Sci
Title: LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.
Volume: 117
Issue: Pt 13
Pages: 2805-12
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Publication
12473658 | -
First Author: Scherz-Shouval R
Year: 2003
Journal: J Biol Chem
Title: The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A.
Volume: 278
Issue: 16
Pages: 14053-8
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Publication
19491929 | -
First Author: Nakatogawa H
Year: 2009
Journal: Nat Rev Mol Cell Biol
Title: Dynamics and diversity in autophagy mechanisms: lessons from yeast.
Volume: 10
Issue: 7
Pages: 458-67
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Publication
20811353 | -
First Author: Yang Z
Year: 2010
Journal: Nat Cell Biol
Title: Eaten alive: a history of macroautophagy.
Volume: 12
Issue: 9
Pages: 814-22
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Protein
A0A7N9VT17
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
A0A7N9VS64
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Protein
A0A0G2JFS9
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q5EBK1
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Gene
108698409 | LOC108698409
Type: gene
Organism: frog, African clawed
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Protein Coding Gene
MGP_CAROLIEiJ_G0033457 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036043 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035817 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2147903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035243 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031996 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034627 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
26805760 | J:231471
First Author: Zhang L
Year: 2016
Journal: Cancer Lett
Title: Unraveling the roles of Atg4 proteases from autophagy modulation to targeted cancer therapy.
Volume: 373
Issue: 1
Pages: 19-26
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GXD Expression
GXD Expression
 
Probe: MGI:2310588
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4823295
Age: embryonic day 14.5
Image: euxassay_008404_17
Specimen Label: euxassay_008404_17
Detected: true
Specimen Num: 1
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Publication
- | J:193309
       
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
36198274 | J:329967
First Author: Li H
Year: 2022
Journal: Cell Rep
Title: Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.
Volume: 41
Issue: 1
Pages: 111435
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Cysteine protease ATG4A
Type: chain
End: 396
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Protein
A0A7P0A158
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: false
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Publication
30808002 | -
First Author: Mariño G
Year: 2019
Journal: J Biol Chem
Title: Withdrawal: Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.
Volume: 294
Issue: 4
Pages: 1431
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Publication
37459465 | J:341370
First Author: Tamargo-Gómez I
Year: 2023
Journal: Autophagy
Title: Analysis of ATG4C function in vivo.
Volume: 19
Issue: 11
Pages: 2912-2933
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Pseudogene
MGI:3615624 | Atg4a-ps
Type: pseudogene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0023174 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036141 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027396 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Pseudogene
MGI_C57BL6J_3615624 | -
Type: pseudogene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028110 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036043 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028165 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031997 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034628 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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