|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 704 for Atr

<< First    < Previous  |  Next >    Last >>
0.075s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Brown EJ
Year: 2000
Journal: Genes Dev
Title: ATR disruption leads to chromosomal fragmentation and early embryonic lethality.
Volume: 14
Issue: 4
Pages: 397-402
Publication
First Author: de Klein A
Year: 2000
Journal: Curr Biol
Title: Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Volume: 10
Issue: 8
Pages: 479-82
Publication
First Author: Brown EJ
Year: 2003
Journal: Genes Dev
Title: Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance.
Volume: 17
Issue: 5
Pages: 615-28
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Keegan KS
Year: 1996
Journal: Genes Dev
Title: The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.
Volume: 10
Issue: 19
Pages: 2423-37
Publication
First Author: O'Driscoll M
Year: 2009
Journal: DNA Repair (Amst)
Title: Mouse models for ATR deficiency.
Volume: 8
Issue: 11
Pages: 1333-7
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Publication
First Author: Kogo H
Year: 2012
Journal: Genes Cells
Title: HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.
Volume: 17
Issue: 11
Pages: 897-912
Publication
First Author: Menolfi D
Year: 2018
Journal: Nat Commun
Title: Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.
Volume: 9
Issue: 1
Pages: 5351
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Pacheco S
Year: 2018
Journal: Nat Commun
Title: ATR is required to complete meiotic recombination in mice.
Volume: 9
Issue: 1
Pages: 2622
Publication
First Author: Royo H
Year: 2013
Journal: Genes Dev
Title: ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing.
Volume: 27
Issue: 13
Pages: 1484-94
Publication
First Author: Moens PB
Year: 1999
Journal: Chromosoma
Title: The association of ATR protein with mouse meiotic chromosome cores.
Volume: 108
Issue: 2
Pages: 95-102
Publication
First Author: Widger A
Year: 2018
Journal: Nat Commun
Title: ATR is a multifunctional regulator of male mouse meiosis.
Volume: 9
Issue: 1
Pages: 2621
Publication
First Author: Lee Y
Year: 2012
Journal: EMBO J
Title: ATR maintains select progenitors during nervous system development.
Volume: 31
Issue: 5
Pages: 1177-89
Publication
First Author: Brown AD
Year: 2014
Journal: PLoS One
Title: ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair.
Volume: 9
Issue: 3
Pages: e91222
Publication
First Author: Ragland RL
Year: 2009
Journal: Mamm Genome
Title: Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response.
Volume: 20
Issue: 6
Pages: 375-85
Publication
First Author: Enriquez-Rios V
Year: 2017
Journal: J Neurosci
Title: DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Volume: 37
Issue: 4
Pages: 893-905
Publication
First Author: Fedoriw AM
Year: 2015
Journal: Development
Title: Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.
Volume: 142
Issue: 17
Pages: 2972-80
Publication
First Author: Toledo LI
Year: 2008
Journal: Genes Dev
Title: ATR signaling can drive cells into senescence in the absence of DNA breaks.
Volume: 22
Issue: 3
Pages: 297-302
Publication
First Author: Yu Z
Year: 2012
Journal: Cell Res
Title: The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Volume: 22
Issue: 2
Pages: 305-20
Publication
First Author: Lopez-Contreras AJ
Year: 2015
Journal: Genes Dev
Title: Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.
Volume: 29
Issue: 7
Pages: 690-5
Publication
First Author: McNees CJ
Year: 2010
Journal: J Cell Biol
Title: ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Volume: 188
Issue: 5
Pages: 639-52
Publication
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
Publication
First Author: Perera D
Year: 2004
Journal: Mol Biol Cell
Title: TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.
Volume: 15
Issue: 4
Pages: 1568-79
Publication
First Author: Valdés-Sánchez L
Year: 2013
Journal: Hum Mol Genet
Title: ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.
Volume: 22
Issue: 8
Pages: 1507-15
Publication
First Author: Ouyang Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.
Volume: 337
Issue: 3
Pages: 875-80
Publication
First Author: Ruiz S
Year: 2016
Journal: Mol Cell
Title: A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Volume: 62
Issue: 2
Pages: 307-13
Publication
First Author: Liu H
Year: 2010
Journal: Nature
Title: Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Volume: 467
Issue: 7313
Pages: 343-6
Publication
First Author: Ruzankina Y
Year: 2009
Journal: Nat Genet
Title: Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.
Volume: 41
Issue: 10
Pages: 1144-9
Publication
First Author: Fang Y
Year: 2004
Journal: EMBO J
Title: ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
Volume: 23
Issue: 15
Pages: 3164-74
Publication
First Author: Cheng A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.
Volume: 115
Issue: 2
Pages: E292-E301
Publication
First Author: Kedar PS
Year: 2008
Journal: DNA Repair (Amst)
Title: Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.
Volume: 7
Issue: 11
Pages: 1787-98
Publication
First Author: Ruzankina Y
Year: 2007
Journal: Cell Stem Cell
Title: Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.
Volume: 1
Issue: 1
Pages: 113-26
Publication
First Author: Entezam A
Year: 2008
Journal: Nucleic Acids Res
Title: ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.
Volume: 36
Issue: 3
Pages: 1050-6
Publication
First Author: Denchi EL
Year: 2007
Journal: Nature
Title: Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Volume: 448
Issue: 7157
Pages: 1068-71
Publication
First Author: Hitomi M
Year: 2008
Journal: Mol Cell Biol
Title: Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression.
Volume: 28
Issue: 17
Pages: 5478-93
Publication
First Author: Lang PY
Year: 2016
Journal: Development
Title: ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
Volume: 143
Issue: 21
Pages: 4038-4052
Publication
First Author: Gilad O
Year: 2010
Journal: Cancer Res
Title: Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.
Volume: 70
Issue: 23
Pages: 9693-702
Publication
First Author: Kulkarni A
Year: 2008
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.
Volume: 294
Issue: 5
Pages: L998-L1006
Publication
First Author: Entezam A
Year: 2009
Journal: Nucleic Acids Res
Title: ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice.
Volume: 37
Issue: 19
Pages: 6371-7
Publication
First Author: Wojtasz L
Year: 2012
Journal: Genes Dev
Title: Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.
Volume: 26
Issue: 9
Pages: 958-73
Publication
First Author: Refolio E
Year: 2011
Journal: J Cell Sci
Title: The Ddc2/ATRIP checkpoint protein monitors meiotic recombination intermediates.
Volume: 124
Issue: Pt 14
Pages: 2488-500
Publication
First Author: Zhou ZW
Year: 2013
Journal: PLoS Genet
Title: An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.
Volume: 9
Issue: 8
Pages: e1003702
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Onksen JL
Year: 2012
Journal: Genes Brain Behav
Title: Running-induced anxiety is dependent on increases in hippocampal neurogenesis.
Volume: 11
Issue: 5
Pages: 529-38
Publication
First Author: Kibe T
Year: 2016
Journal: Mol Cell
Title: TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.
Volume: 61
Issue: 2
Pages: 236-46
Publication
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
Publication
First Author: López-Contreras AJ
Year: 2012
Journal: J Exp Med
Title: An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
Volume: 209
Issue: 3
Pages: 455-61
Publication
First Author: Sfeir A
Year: 2009
Journal: Cell
Title: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Volume: 138
Issue: 1
Pages: 90-103
Publication
First Author: Ragland RL
Year: 2013
Journal: Genes Dev
Title: RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.
Volume: 27
Issue: 20
Pages: 2259-73
Publication
First Author: Mu XF
Year: 2011
Journal: Biol Reprod
Title: DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.
Volume: 85
Issue: 3
Pages: 524-35
Publication
First Author: Takai KK
Year: 2011
Journal: Mol Cell
Title: Telomere protection by TPP1/POT1 requires tethering to TIN2.
Volume: 44
Issue: 4
Pages: 647-59
Publication
First Author: Turner JM
Year: 2004
Journal: Curr Biol
Title: BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.
Volume: 14
Issue: 23
Pages: 2135-42
Publication
First Author: Kawasumi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.
Volume: 108
Issue: 33
Pages: 13716-21
Publication
First Author: Ishii H
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Volume: 102
Issue: 27
Pages: 9655-60
Publication
First Author: Murga M
Year: 2009
Journal: Nat Genet
Title: A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging.
Volume: 41
Issue: 8
Pages: 891-8
Publication
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
Publication
First Author: Schoppy DW
Year: 2012
Journal: J Clin Invest
Title: Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.
Volume: 122
Issue: 1
Pages: 241-52
Publication
First Author: Bellani MA
Year: 2005
Journal: J Cell Sci
Title: SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.
Volume: 118
Issue: Pt 15
Pages: 3233-45
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: El-Shemerly M
Year: 2008
Journal: Nucleic Acids Res
Title: ATR-dependent pathways control hEXO1 stability in response to stalled forks.
Volume: 36
Issue: 2
Pages: 511-9
GXD Expression      
Probe: MGI:5293842
Assay Type: Western blot
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5293844
Age: embryonic day 1.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3795588
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3795588
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3795588
Age: embryonic day 17.0
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3795588
Age: embryonic day 15.0
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3795588
Age: embryonic day 11.0
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3795588
Age: embryonic day 7.0
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6287132
Assay Type: RT-PCR
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Stage: TS04
Assay Id: MGI:6287210
Age: embryonic day 3.0
Image: 4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6287132
Assay Type: RT-PCR
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Stage: TS04
Assay Id: MGI:6287210
Age: embryonic day 3.0
Image: 4
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6287132
Assay Type: RT-PCR
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Stage: TS04
Assay Id: MGI:6287210
Age: embryonic day 3.0
Image: 4
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3795588
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3795588
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:33233
Assay Type: Northern blot
Annotation Date: 2008-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3795588
Age: postnatal adult
Detected: true
Specimen Num: 7