Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
wallaby, tammar |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Clynes D |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
ATRX dysfunction induces replication defects in primary mouse cells. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e92915 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong LH |
Year: |
2010 |
Journal: |
Genome Res |
Title: |
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. |
Volume: |
20 |
Issue: |
3 |
Pages: |
351-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kernohan KD |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. |
Volume: |
18 |
Issue: |
2 |
Pages: |
191-202 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picketts DJ |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains. |
Volume: |
9 |
Issue: |
5 |
Pages: |
400-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nan X |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. |
Volume: |
104 |
Issue: |
8 |
Pages: |
2709-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lagali PS |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Retinal interneuron survival requires non-cell-autonomous Atrx activity. |
Volume: |
25 |
Issue: |
21 |
Pages: |
4787-4803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Solomon LA |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Loss of ATRX does not confer susceptibility to osteoarthritis. |
Volume: |
8 |
Issue: |
12 |
Pages: |
e85526 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldberg AD |
Year: |
2010 |
Journal: |
Cell |
Title: |
Distinct factors control histone variant H3.3 localization at specific genomic regions. |
Volume: |
140 |
Issue: |
5 |
Pages: |
678-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huh MS |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Compromised genomic integrity impedes muscle growth after Atrx inactivation. |
Volume: |
122 |
Issue: |
12 |
Pages: |
4412-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marano D |
Year: |
2019 |
Journal: |
Int J Mol Sci |
Title: |
ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation. |
Volume: |
20 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bérubé NG |
Year: |
2002 |
Journal: |
Hum Mol Genet |
Title: |
Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice. |
Volume: |
11 |
Issue: |
3 |
Pages: |
253-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rowland ME |
Year: |
2018 |
Journal: |
Aging (Albany NY) |
Title: |
Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. |
Volume: |
10 |
Issue: |
6 |
Pages: |
1223-1238 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaspar TB |
Year: |
2022 |
Journal: |
Cancers (Basel) |
Title: |
Characterisation of an Atrx Conditional Knockout Mouse Model: Atrx Loss Causes Endocrine Dysfunction Rather Than Pancreatic Neuroendocrine Tumour. |
Volume: |
14 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Huh MS |
Year: |
2016 |
Journal: |
Cell Death Dis |
Title: |
Stalled replication forks within heterochromatin require ATRX for protection. |
Volume: |
7 |
|
Pages: |
e2220 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun C |
Year: |
2022 |
Journal: |
Dis Model Mech |
Title: |
Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas. |
Volume: |
15 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Solomon LA |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Loss of ATRX in chondrocytes has minimal effects on skeletal development. |
Volume: |
4 |
Issue: |
9 |
Pages: |
e7106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaspar TB |
Year: |
2023 |
Journal: |
Cancers (Basel) |
Title: |
Generation of an Obese Diabetic Mouse Model upon Conditional Atrx Disruption. |
Volume: |
15 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sailau ZK |
Year: |
2017 |
Journal: |
Acta Histochem |
Title: |
Nuclear distribution of the chromatin-remodeling protein ATRX in mouse early embryogenesis. |
Volume: |
119 |
Issue: |
1 |
Pages: |
18-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bérubé NG |
Year: |
2005 |
Journal: |
J Clin Invest |
Title: |
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. |
Volume: |
115 |
Issue: |
2 |
Pages: |
258-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koschmann C |
Year: |
2016 |
Journal: |
Sci Transl Med |
Title: |
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma. |
Volume: |
8 |
Issue: |
328 |
Pages: |
328ra28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huyhn K |
Year: |
2011 |
Journal: |
BMC Dev Biol |
Title: |
ATRX has a critical and conserved role in mammalian sexual differentiation. |
Volume: |
11 |
|
Pages: |
39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamming RJ |
Year: |
2017 |
Journal: |
Dis Model Mech |
Title: |
Mosaic expression of Atrx in the mouse central nervous system causes memory deficits. |
Volume: |
10 |
Issue: |
2 |
Pages: |
119-126 |
|
•
•
•
•
•
|
Publication |
First Author: |
Conte D |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Loss of Atrx sensitizes cells to DNA damaging agents through p53-mediated death pathways. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e52167 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nogami T |
Year: |
2011 |
Journal: |
Hippocampus |
Title: |
Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice. |
Volume: |
21 |
Issue: |
6 |
Pages: |
678-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Levy MA |
Year: |
2008 |
Journal: |
BMC Genomics |
Title: |
The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome. |
Volume: |
9 |
|
Pages: |
468 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6259658 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-12-10 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3187710 |
Pattern: |
Not Specified |
Stage: |
TS10 |
Assay Id: |
MGI:6259659 |
Age: |
embryonic day 7.0 |
Image: |
S1E |
Note: |
Biallelic Atrx expression was shown. |
Specimen Label: |
S1E |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Danussi C |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. |
Volume: |
9 |
Issue: |
1 |
Pages: |
1057 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rowland ME |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice. |
Volume: |
14 |
Issue: |
1 |
Pages: |
7090 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lovejoy CA |
Year: |
2020 |
Journal: |
PLoS Biol |
Title: |
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity. |
Volume: |
18 |
Issue: |
1 |
Pages: |
e3000594 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watson LA |
Year: |
2013 |
Journal: |
J Clin Invest |
Title: |
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. |
Volume: |
123 |
Issue: |
5 |
Pages: |
2049-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bartholf DeWitt S |
Year: |
2022 |
Journal: |
JCI Insight |
Title: |
Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding. |
Volume: |
7 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Levy MA |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions. |
Volume: |
24 |
Issue: |
7 |
Pages: |
1824-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huh MS |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Recovery from impaired muscle growth arises from prolonged postnatal accretion of myonuclei in Atrx mutant mice. |
Volume: |
12 |
Issue: |
11 |
Pages: |
e0186989 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamming RJ |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits. |
Volume: |
31 |
Issue: |
13 |
Pages: |
107838 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garrick D |
Year: |
2006 |
Journal: |
PLoS Genet |
Title: |
Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues. |
Volume: |
2 |
Issue: |
4 |
Pages: |
e58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baumann C |
Year: |
2010 |
Journal: |
PLoS Genet |
Title: |
Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo. |
Volume: |
6 |
Issue: |
9 |
Pages: |
e1001137 |
|
•
•
•
•
•
|
Publication |
First Author: |
Floyd W |
Year: |
2023 |
Journal: |
J Clin Invest |
Title: |
Atrx deletion impairs CGAS/STING signaling and increases sarcoma response to radiation and oncolytic herpesvirus. |
Volume: |
133 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ritchie K |
Year: |
2014 |
Journal: |
Biol Open |
Title: |
ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain. |
Volume: |
3 |
Issue: |
12 |
Pages: |
1158-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kernohan KD |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping. |
Volume: |
42 |
Issue: |
13 |
Pages: |
8356-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seah C |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. |
Volume: |
28 |
Issue: |
47 |
Pages: |
12570-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Medina CF |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome. |
Volume: |
18 |
Issue: |
5 |
Pages: |
966-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Young CC |
Year: |
2019 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice. |
Volume: |
7 |
Issue: |
1 |
Pages: |
93-113 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shioda N |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. |
Volume: |
31 |
Issue: |
1 |
Pages: |
346-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fuentes ME |
Year: |
2024 |
Journal: |
Sci Rep |
Title: |
Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice. |
Volume: |
14 |
Issue: |
1 |
Pages: |
8510 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lewis PW |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. |
Volume: |
107 |
Issue: |
32 |
Pages: |
14075-80 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5609447 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-07-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160331 |
Pattern: |
Not Specified |
Stage: |
TS01 |
Assay Id: |
MGI:6438169 |
Age: |
embryonic day 0.5 |
|
Note: |
Atrx is a nuclear matrix marker during interphase. |
Specimen Label: |
S2B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:160331 |
Pattern: |
Not Specified |
Stage: |
TS01 |
Assay Id: |
MGI:7384973 |
Age: |
embryonic day 0.5 |
|
Note: |
There was no colocalization of Atrx with Daxx immunolabeling at the late zygote stage. |
Specimen Label: |
4a |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5609447 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-05-10 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2910625 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:7628671 |
Age: |
embryonic day 17.5 |
Image: |
S1 Control |
Note: |
Strong Atrx expression in nuclear speckle co-localized with focus of Gata4 expression. |
Specimen Label: |
S1 Control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6259658 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-12-10 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1604210 |
Pattern: |
Regionally restricted |
Stage: |
TS10 |
Assay Id: |
MGI:6259659 |
Age: |
embryonic day 7.0 |
Image: |
S1D |
Note: |
Two nuclei in the chorion - one monoallelic and one biallelic Atrx expression. |
Specimen Label: |
S1D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5609447 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-12-10 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3187710 |
Pattern: |
Not Specified |
Stage: |
TS10 |
Assay Id: |
MGI:6259666 |
Age: |
embryonic day 7.0 |
Image: |
S1C |
Note: |
Partial overlap of Atrx label with Xist expression domain was noted. |
Specimen Label: |
S1C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:160403 |
Pattern: |
Not Specified |
Stage: |
TS03 |
Assay Id: |
MGI:7384973 |
Age: |
embryonic day 3.0 |
|
Note: |
There was no colocalization of Atrx with Daxx immunolabeling at the morula stage. |
Specimen Label: |
4c |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Regionally restricted |
Stage: |
TS02 |
Assay Id: |
MGI:7384974 |
Age: |
embryonic day 1.0 |
|
Note: |
Daxx gold particles and Atrx gold particles were noted in separate heterochromatin structures. |
Specimen Label: |
2c |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Regionally restricted |
Stage: |
TS02 |
Assay Id: |
MGI:7384973 |
Age: |
embryonic day 1.0 |
|
Note: |
Daxx and Atrx colocalization in the nucleus of 2-cell mouse embryos. |
Specimen Label: |
5a |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eustermann S |
Year: |
2011 |
Journal: |
Nat Struct Mol Biol |
Title: |
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin. |
Volume: |
18 |
Issue: |
7 |
Pages: |
777-82 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Regionally restricted |
Stage: |
TS02 |
Assay Id: |
MGI:7384974 |
Age: |
embryonic day 1.0 |
|
Note: |
Daxx gold particles and Atrx gold particles were noted in a single structure in close proximity to the surface of interchromatin granule cluster. |
Specimen Label: |
2d |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5609447 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-12-10 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1604210 |
Pattern: |
Regionally restricted |
Stage: |
TS10 |
Assay Id: |
MGI:6259666 |
Age: |
embryonic day 7.0 |
Image: |
S1B |
Note: |
There was no overlap of the Atrx protein with Xist staining in the two nuclei from chorion shown in the figure. Only 5.8% of chorion nuclei show partial overlap of expression. |
Specimen Label: |
S1B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2476
 |
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5609447 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-02-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Not Specified |
Stage: |
TS02 |
Assay Id: |
MGI:6117769 |
Age: |
embryonic day 1.0 |
|
Note: |
Intense staining were observed at the periphery of the nucleolus precursor bodies, together with a diffuse staining of the nucleoplasm. A colocalization of heterochromatin and ATRX was detected in some areas at the nucleolus precursor body periphery. The presence of heterochromatin areas that do not contain ATRX is clearly seen. |
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7384879 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-11-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Regionally restricted |
Stage: |
TS02 |
Assay Id: |
MGI:7384973 |
Age: |
embryonic day 1.0 |
|
Note: |
At late two-cell stage, colocalization of Daxx and ATRX was detectable both in the ring-shaped heterochromatin zones associated with the nucleolus precursor body (NPB) periphery and in NPB-unassociated heterochromatin patches. Some zones of Daxx localization did not overlap with ATRX (and vise versa). ATRX was found in 60% Daxx-positive heterochromatin areas associated with NPBs and in 80% Daxx-positive heterochromatin clumps located outside the NPBs. |
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le Douarin B |
Year: |
1996 |
Journal: |
EMBO J |
Title: |
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. |
Volume: |
15 |
Issue: |
23 |
Pages: |
6701-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaguchi K |
Year: |
2018 |
Journal: |
Int J Mol Sci |
Title: |
SA4503, A Potent Sigma-1 Receptor Ligand, Ameliorates Synaptic Abnormalities and Cognitive Dysfunction in a Mouse Model of ATR-X Syndrome. |
Volume: |
19 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Muers MR |
Year: |
2007 |
Journal: |
Am J Hum Genet |
Title: |
Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model. |
Volume: |
80 |
Issue: |
6 |
Pages: |
1138-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shioda N |
Year: |
2018 |
Journal: |
Nat Med |
Title: |
Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome. |
Volume: |
24 |
Issue: |
6 |
Pages: |
802-813 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tillotson R |
Year: |
2023 |
Journal: |
Hum Mol Genet |
Title: |
A new mouse model of ATR-X syndrome carrying a common patient mutation exhibits neurological and morphological defects. |
Volume: |
32 |
Issue: |
15 |
Pages: |
2485-2501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kugler J |
Year: |
2017 |
Journal: |
Carcinogenesis |
Title: |
Elevated HMGN4 expression potentiates thyroid tumorigenesis. |
Volume: |
38 |
Issue: |
4 |
Pages: |
391-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lagali PS |
Year: |
2021 |
Journal: |
Neuroscience |
Title: |
Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina. |
Volume: |
452 |
|
Pages: |
169-180 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bogolyubova IO |
Year: |
2019 |
Journal: |
Acta Histochem |
Title: |
The dynamics of DAXX protein distribution in the nucleus of mouse early embryos. |
Volume: |
121 |
Issue: |
4 |
Pages: |
522-529 |
|
•
•
•
•
•
|
Publication |
First Author: |
León NY |
Year: |
2024 |
Journal: |
iScience |
Title: |
Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. |
Volume: |
27 |
Issue: |
5 |
Pages: |
109629 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishov AM |
Year: |
2004 |
Journal: |
J Cell Sci |
Title: |
Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. |
Volume: |
117 |
Issue: |
Pt 17 |
Pages: |
3807-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
De La Fuente R |
Year: |
2004 |
Journal: |
Dev Biol |
Title: |
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. |
Volume: |
272 |
Issue: |
1 |
Pages: |
1-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang FT |
Year: |
2013 |
Journal: |
Nucleic Acids Res |
Title: |
PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells. |
Volume: |
41 |
Issue: |
8 |
Pages: |
4447-58 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Transcriptional regulator ATRX |
Type: |
chain |
End: |
2476 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Solomon LA |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly. |
Volume: |
22 |
Issue: |
24 |
Pages: |
5015-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagheri-Fam S |
Year: |
2011 |
Journal: |
Hum Mol Genet |
Title: |
Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. |
Volume: |
20 |
Issue: |
11 |
Pages: |
2213-24 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|