Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Aurora kinase B (AURKB, also known as Aurora 1) is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis []. AURKB has various mitotic functions, including chromosome-microtubule interactions, sister chromatid cohesion, the spindle-assembly checkpoint and cytokinesis [, , ]. It phosphorylates chromatin proteins such as histone H3 to aid in mitotic chromosome condensation and contributes to the spindlecheckpoint []. Its expression is cell cycle-regulated, with a low in G1/S, an increase during G2 and M [].The Aurora kinases are highly conserved serine/threonine kinases that regulate chromosomal alignment and segregation during mitosis and meiosis. Three mammalian Aurora kinases, Aurora A, B and C, have been identified. They all contain a protein kinase domain and a destruction box (D-box) recognised by the multi-subunit E3-ubiquitin ligase anaphase promoting complex/cyclosome (APC/C), which mediates their proteasomal degradation. However, their N-terminal domain share little sequence identity and confer unique protein-protein interaction abilities among the Aurora kinases []. They are differentially expressed at high levels in rapidly dividing tissues such as hematopoietic cells (A and B) and germ cells (C only). Their expression is low or absent in most adult tissues due to their lower rates of proliferation []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672825 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 17.5 |
Image: |
3B E17.5 Aurkb |
Note: |
Expression dramatically reduced. No expression in Sox9+ cells at E17.5. |
Specimen Label: |
3B E17.5 Aurkb |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286621 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 13.5 |
Image: |
3B E13.5 Aurkb |
Note: |
Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively. |
Specimen Label: |
3B E13.5 Aurkb |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 15.5 |
Image: |
3B E15.5 Aurkb |
Note: |
Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively. |
Specimen Label: |
3B E15.5 Aurkb |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 13.5 |
Image: |
3B E13.5 Aurkb |
Note: |
Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively. |
Specimen Label: |
3B E13.5 Aurkb |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 15.5 |
Image: |
3B E15.5 Aurkb |
Note: |
Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively. |
Specimen Label: |
3B E15.5 Aurkb |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286025 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:6755206 |
Age: |
embryonic day 17.5 |
Image: |
3B E17.5 Aurkb |
Note: |
Expression in only a small number of Cdh1+ cells epithelial cells. |
Specimen Label: |
3B E17.5 Aurkb |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4354213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4354786 |
Age: |
embryonic day 14.5 |
Image: |
5F & Table S5 - Aurkb |
|
Specimen Label: |
5F & Table S5 - Aurkb |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4354213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4354786 |
Age: |
embryonic day 14.5 |
Image: |
5F & Table S5 - Aurkb |
Note: |
There is no expression in either the upper or lower cortical plate. |
Specimen Label: |
5F & Table S5 - Aurkb |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4354213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4354786 |
Age: |
embryonic day 14.5 |
Image: |
5F & Table S5 - Aurkb |
|
Specimen Label: |
5F & Table S5 - Aurkb |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen AL |
Year: |
2018 |
Journal: |
Curr Biol |
Title: |
Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis. |
Volume: |
28 |
Issue: |
21 |
Pages: |
3458-3468.e5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-12-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7788225 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression in midbodies. |
Specimen Label: |
1H control Aurkb |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6755203 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-12-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7788225 |
Age: |
embryonic day 15.5 |
|
Note: |
Decrease in percentage of Aurkb-expressing midbodies. |
Specimen Label: |
1H cKO Aurkb |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasui Y |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. |
Volume: |
279 |
Issue: |
13 |
Pages: |
12997-3003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wheatley SP |
Year: |
2001 |
Journal: |
Curr Biol |
Title: |
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. |
Volume: |
11 |
Issue: |
11 |
Pages: |
886-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruchaud S |
Year: |
2007 |
Journal: |
Nat Rev Mol Cell Biol |
Title: |
Chromosomal passengers: conducting cell division. |
Volume: |
8 |
Issue: |
10 |
Pages: |
798-812 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le LT |
Year: |
2013 |
Journal: |
Biol Open |
Title: |
Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase. |
Volume: |
2 |
Issue: |
4 |
Pages: |
379-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krenn V |
Year: |
2015 |
Journal: |
Front Oncol |
Title: |
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. |
Volume: |
5 |
|
Pages: |
225 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carmena M |
Year: |
2003 |
Journal: |
Nat Rev Mol Cell Biol |
Title: |
The cellular geography of aurora kinases. |
Volume: |
4 |
Issue: |
11 |
Pages: |
842-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldenson B |
Year: |
2015 |
Journal: |
Oncogene |
Title: |
The aurora kinases in cell cycle and leukemia. |
Volume: |
34 |
Issue: |
5 |
Pages: |
537-45 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
345
 |
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5617020 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284220 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6400916 |
Age: |
embryonic day 12.5 |
Image: |
6E |
Note: |
Virtually no cleaved Casp3+ cells were positively stained with Aurkb (2.1%). |
Specimen Label: |
6E |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6159093 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:6755210 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Ct Sox9 |
Note: |
Expression clearly observed at tips of branching lung buds. |
Specimen Label: |
4E Aurkb Ct Sox9 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5430034 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672819 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755211 |
Age: |
embryonic day 11.5 |
Image: |
4D Aurkb Ct Sox2 |
|
Specimen Label: |
4D Aurkb Ct Sox2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5430034 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672819 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755211 |
Age: |
embryonic day 11.5 |
Image: |
4D Aurkb Shh-Cre Sox2 |
|
Specimen Label: |
4D Aurkb Shh-Cre Sox2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6159093 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6755210 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Shh-Cre Sox9 |
|
Specimen Label: |
4E Aurkb Shh-Cre Sox9 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6159093 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1685319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755210 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Ct Sox9 |
Note: |
Expression in precursors of cartilage of trachea. |
Specimen Label: |
4E Aurkb Ct Sox9 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2676171 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1685319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755212 |
Age: |
embryonic day 11.5 |
Image: |
4D Aurkb Ct Nkx2.1 |
|
Specimen Label: |
4D Aurkb Ct Nkx2.1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2676171 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1685319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755212 |
Age: |
embryonic day 11.5 |
Image: |
4D Aurkb Shh-Cre Nkx2.1 |
Note: |
Expression in remnant ot trachea, indicating separation of trachea from esophagus and lung specification had occurred. |
Specimen Label: |
4D Aurkb Shh-Cre Nkx2.1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6159093 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1685319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6755210 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Shh-Cre Sox9 |
Note: |
Expression in precursors of cartilage of trachea. |
Specimen Label: |
4E Aurkb Shh-Cre Sox9 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1935187 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286019 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:6755208 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Ct E-cadherin |
Note: |
Expression in branched epithelial structure. |
Specimen Label: |
4E Aurkb Ct E-cadherin |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1935187 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286019 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:6755208 |
Age: |
embryonic day 11.5 |
Image: |
4E Aurkb Shh-Cre E-cadherin |
Note: |
Expression in primitive epithelial structure. |
Specimen Label: |
4E Aurkb Shh-Cre E-cadherin |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2676171 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286019 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:6755213 |
Age: |
embryonic day 11.5 |
Image: |
4F Aurkb Ct |
Note: |
Expression in branched epithelial structure. |
Specimen Label: |
4F Aurkb Ct |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2676171 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286019 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:6755213 |
Age: |
embryonic day 11.5 |
Image: |
4F Aurkb Shh-Cre |
Note: |
Expression in primitive epithelial structure. |
Specimen Label: |
4F Aurkb Shh-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5617020 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284220 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6400916 |
Age: |
embryonic day 12.5 |
Image: |
6C |
Note: |
Quantification of cells with G2-specific Aurkb staining in the E12 mutant pallium revealed that 14.4% of Trp53-upregulating cells were in G2 phase, a significantly lower percentage than expected. |
Specimen Label: |
6C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jang J |
Year: |
2020 |
Journal: |
Front Cell Dev Biol |
Title: |
An Engineered Mouse to Identify Proliferating Cells and Their Derivatives. |
Volume: |
8 |
|
Pages: |
388 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimmins S |
Year: |
2007 |
Journal: |
Mol Endocrinol |
Title: |
Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis. |
Volume: |
21 |
Issue: |
3 |
Pages: |
726-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vazquez BN |
Year: |
2021 |
Journal: |
MicroPubl Biol |
Title: |
An analog-sensitive allele of Aurora kinase B is lethal in mouse. |
Volume: |
2021 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Chan FL |
Year: |
2017 |
Journal: |
Nucleic Acids Res |
Title: |
Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity. |
Volume: |
45 |
Issue: |
21 |
Pages: |
12340-12353 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shuda K |
Year: |
2009 |
Journal: |
Mol Reprod Dev |
Title: |
Aurora kinase B modulates chromosome alignment in mouse oocytes. |
Volume: |
76 |
Issue: |
11 |
Pages: |
1094-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin J |
Year: |
2016 |
Journal: |
Elife |
Title: |
Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells. |
Volume: |
5 |
|
Pages: |
e10877 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balboula AZ |
Year: |
2014 |
Journal: |
PLoS Genet |
Title: |
Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. |
Volume: |
10 |
Issue: |
2 |
Pages: |
e1004194 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schindler K |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development. |
Volume: |
109 |
Issue: |
33 |
Pages: |
E2215-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellard SR |
Year: |
2020 |
Journal: |
J Cell Sci |
Title: |
Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis. |
Volume: |
133 |
Issue: |
23 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
González-Loyola A |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development. |
Volume: |
35 |
Issue: |
20 |
Pages: |
3566-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aboelenain M |
Year: |
2021 |
Journal: |
Development |
Title: |
Aurora kinase B inhibits aurora kinase A to control maternal mRNA translation in mouse oocytes. |
Volume: |
148 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ah-Cann C |
Year: |
2021 |
Journal: |
Development |
Title: |
A functional genetic screen identifies aurora kinase b as an essential regulator of Sox9-positive mouse embryonic lung progenitor cells. |
Volume: |
148 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Niwa H |
Year: |
1996 |
Journal: |
Gene |
Title: |
Cell-cycle-dependent expression of the STK-1 gene encoding a novel murine putative protein kinase. |
Volume: |
169 |
Issue: |
2 |
Pages: |
197-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura M |
Year: |
1998 |
Journal: |
Cytogenet Cell Genet |
Title: |
Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1. |
Volume: |
82 |
Issue: |
3-4 |
Pages: |
147-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Geddis AE |
Year: |
2004 |
Journal: |
Blood |
Title: |
Megakaryocytes express functional Aurora-B kinase in endomitosis. |
Volume: |
104 |
Issue: |
4 |
Pages: |
1017-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amabile G |
Year: |
2009 |
Journal: |
Cell Death Differ |
Title: |
The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts. |
Volume: |
16 |
Issue: |
2 |
Pages: |
321-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu W |
Year: |
2020 |
Journal: |
Front Cell Dev Biol |
Title: |
An Aurora Kinase B-Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. |
Volume: |
8 |
|
Pages: |
570252 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Absent |
Sex: |
Pooled |
Emaps: |
EMAPS:1754428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1697428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1754928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:3280928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1757728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:3599828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1619828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1720228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Absent |
Sex: |
Pooled |
Emaps: |
EMAPS:1750328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
false |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Not Specified |
Sex: |
Pooled |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
|
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1204812 |
Assay Type: |
RT-PCR |
Annotation Date: |
1998-06-01 |
Strength: |
Present |
Sex: |
Pooled |
Emaps: |
EMAPS:1832128 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1204814 |
Age: |
postnatal week 6-8 |
Image: |
st96_281 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|