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Search results 1 to 100 out of 406 for Auts2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
26053 | AUTS2
Type: gene
Organism: human
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Gene
100498056 | auts2
Type: gene
Organism: frog, western clawed
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Gene
304419 | Auts2
Type: gene
Organism: rat
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Gene
463457 | AUTS2
Type: gene
Organism: chimpanzee
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Gene
479709 | AUTS2
Type: gene
Organism: dog, domestic
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Gene
615936 | AUTS2
Type: gene
Organism: cattle
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Gene
417481 | AUTS2
Type: gene
Organism: chicken
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Gene
701038 | AUTS2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1919847 | Auts2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR023246 | AUTS2
Type: Family
Description: AUTS2 is a novel gene identified in a monozygotic twin pair with autism; its translation product is a large protein containing 1,295 amino acids []. Following DNA sequence analysis of autism subjects and controls, no autism-specific mutation was observed. Association and linkage analyses were also negative. It is hence considered unlikely that AUTS2 is an autism suspecptibility gene for idiopathic autism, although it may be the gene responsible for the disorder in the twins in this study []. The AUTS2 gene product shares a high level of similarity with the so-called fibrosin-1-like protein, a functionally uncharacterised polypeptide that contains C-terminal Ala-rich and Pro-rich regions.
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Protein
Q6PED7
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: true
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Protein
Q8VDM3
Organism: Mus musculus/domesticus
Length: 792  
Fragment?: true
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Publication
31554716 | J:291007
First Author: Weisner PA
Year: 2019
Journal: G3 (Bethesda)
Title: A Mouse Mutation That Dysregulates Neighboring Galnt17 and Auts2 Genes Is Associated with Phenotypes Related to the Human AUTS2 Syndrome.
Volume: 9
Issue: 11
Pages: 3891-3906
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Publication
25533347 | J:243531
First Author: Hori K
Year: 2014
Journal: Cell Rep
Title: Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis.
Volume: 9
Issue: 6
Pages: 2166-79
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Publication
34013328 | J:322808
First Author: Castanza AS
Year: 2021
Journal: Cereb Cortex
Title: AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice.
Volume: 31
Issue: 10
Pages: 4808-4824
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Publication
32498016 | J:307246
First Author: Hori K
Year: 2020
Journal: iScience
Title: AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication.
Volume: 23
Issue: 6
Pages: 101183
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Publication
27423627 | J:238132
 
First Author: Zhu Y
Year: 2016
Journal: Neuroscience
Title: AUTS2 in the nucleus accumbens is essential for heroin-induced behavioral sensitization.
Volume: 333
Pages: 35-43
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Publication
35235353 | J:331537
First Author: Li J
Year: 2022
Journal: Sci Adv
Title: Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms.
Volume: 8
Issue: 9
Pages: eabk1238
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Publication
33305180 | J:306911
First Author: Yamashiro K
Year: 2020
Journal: iScience
Title: AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.
Volume: 23
Issue: 12
Pages: 101820
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Publication
37816306 | J:356508
 
First Author: Song Y
Year: 2024
Journal: Genetics
Title: Isolated loss of the AUTS2 long isoform, brain-wide or targeted to Calbindin-lineage cells, generates a specific suite of brain, behavioral, and molecular pathologies.
Volume: 226
Issue: 1
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Protein
A0A087WPF7
Organism: Mus musculus/domesticus
Length: 1261  
Fragment?: false
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Protein
Q8R089
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
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Protein
B9EKY2
Organism: Mus musculus/domesticus
Length: 621  
Fragment?: false
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Protein
Q9CSL7
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: true
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Protein
A0A0G2JDI2
Organism: Mus musculus/domesticus
Length: 1008  
Fragment?: false
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Protein
E9Q9T0
Organism: Mus musculus/domesticus
Length: 1031  
Fragment?: false
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Protein
A0A0G2JG68
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: true
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Protein
E9PZ86
Organism: Mus musculus/domesticus
Length: 804  
Fragment?: false
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Protein
Q6ZPN3
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: true
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Protein
Q8BZC7
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: true
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Protein
A0A0U1RNQ7
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Protein
S4R200
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Protein
A0A571BFB2
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
A0A7P0A163
Organism: Mus musculus/domesticus
Length: 1237  
Fragment?: false
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Protein
Q8CCX0
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
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Protein
E9PUB6
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
A0A0G2JFF2
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
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Protein
Q3UX71
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: true
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Protein
A0A0G2JE44
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
A0A0U1RNY3
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: true
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Protein
A0A0U1RPV5
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
A0A1N9PTV1
Organism: Mus musculus/domesticus
Length: 980  
Fragment?: false
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Protein
A0A7N9VSJ5
Organism: Mus musculus/domesticus
Length: 1262  
Fragment?: false
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Protein
Q8C173
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Protein
Q6NSP6
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: true
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Publication
12160723 | -
First Author: Sultana R
Year: 2002
Journal: Genomics
Title: Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins.
Volume: 80
Issue: 2
Pages: 129-34
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Publication
26717414 | J:261355
First Author: Hori K
Year: 2015
Journal: PLoS One
Title: Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory.
Volume: 10
Issue: 12
Pages: e0145979
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Publication
23144223 | J:192361
First Author: Srinivasan K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A network of genetic repression and derepression specifies projection fates in the developing neocortex.
Volume: 109
Issue: 47
Pages: 19071-8
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Publication
34637754 | J:315705
First Author: Liu S
Year: 2021
Journal: Mol Cell
Title: NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.
Volume: 81
Issue: 22
Pages: 4663-4676.e8
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Publication
25519132 | J:217675
First Author: Gao Z
Year: 2014
Journal: Nature
Title: An AUTS2-Polycomb complex activates gene expression in the CNS.
Volume: 516
Issue: 7531
Pages: 349-54
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Publication
19948250 | J:155881
First Author: Bedogni F
Year: 2010
Journal: Gene Expr Patterns
Title: Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.
Volume: 10
Issue: 1
Pages: 9-15
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Publication
30186101 | J:266522
 
First Author: Elsen GE
Year: 2018
Journal: Front Neurosci
Title: The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Volume: 12
Pages: 571
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Protein Coding Gene
MGP_CAROLIEiJ_G0027805 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030581 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029965 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030053 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029327 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024379 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028803 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5447932
Assay Type: Western blot
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:5448140
Age: embryonic day 14.0
Image: 1
Specimen Label: left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276128
Age: postnatal
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276128
Age: postnatal
Image: 6
Specimen Label: Het
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276128
Age: postnatal
Image: 6
Specimen Label: KO
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6276131
Age: embryonic day 13.5
Image: S5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6276131
Age: embryonic day 15.5
Image: S5
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6276131
Age: embryonic day 18.5
Image: S5
Specimen Label: E18.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6276131
Age: postnatal day 3
Image: S5
Specimen Label: P3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276131
Age: postnatal day 5
Image: S5
Specimen Label: P5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276131
Age: postnatal day 21
Image: S5
Specimen Label: P21
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276131
Age: postnatal day 30
Image: S5
Specimen Label: P30
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6276126
Assay Type: Western blot
Annotation Date: 2019-02-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6276131
Age: postnatal day 60
Image: S5
Specimen Label: P60
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5448062
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5448185
Age: embryonic day 14.0
Image: 3C/c
Note: Expressed in a subset of the radial glial progenitors (marked by Pax6).
Specimen Label: 3C/c
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:5448062
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5448185
Age: embryonic day 14.0
Image: 3D/d
Note: Expressed in a subset of the intermediate neuronal progenitors (marked by Tbr2).
Specimen Label: 3D/d
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2024-07-25
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7703751
Age: embryonic day 14.5
Image: 6E
Specimen Label: 6E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7620101
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7620362
Age: postnatal day 0
Image: 7K,L
Note: Expression was detected in both the deep and upper layers of the cortex.
Specimen Label: 7K,L
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7620101
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7620362
Age: postnatal day 0
Image: 7M,N
Note: There was a striking loss of expression in the upper layers of the Satb2 mutants.
Specimen Label: 7M,N
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7620101
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7620362
Age: postnatal day 0
Image: 7K,L
Specimen Label: 7K,L
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7620101
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7620362
Age: postnatal day 0
Image: 7M,N
Note: There was no change to the expression in layers 5 or 6 relative to controls.
Specimen Label: 7M,N
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2813026
Stage: TS26
Assay Id: MGI:5540446
Age: embryonic day 17.5
Image: GUDMAP:15532
Specimen Label: GUDMAP:15532
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5540446
Age: postnatal day 84
Image: GUDMAP:15533
Specimen Label: GUDMAP:15533
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7518771
Assay Type: RNA in situ
Annotation Date: 2023-08-29
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Graded
Stage: TS26
Assay Id: MGI:7522074
Age: embryonic day 18.5
Note: Strong graded expression across the neocortex.
Specimen Label: 7E Dmrt5<+/+>
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7518771
Assay Type: RNA in situ
Annotation Date: 2023-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7522074
Age: embryonic day 18.5
Note: Expression appeared to expand to almost the caudal end of the cortex.
Specimen Label: 7E Dmrt5<-/->
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724650
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421310
Age: embryonic day 14.5
Image: MH862; Specimen C1360
Specimen Label: MH862; Specimen C1360
Detected: true
Specimen Num: 1
•
•
•
•
•




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