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Search results 1 to 80 out of 80 for Awat2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
158835 | AWAT2
Type: gene
Organism: human
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Gene
302425 | Awat2
Type: gene
Organism: rat
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Gene
491936 | AWAT2
Type: gene
Organism: dog, domestic
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Gene
473654 | AWAT2
Type: gene
Organism: chimpanzee
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Gene
521298 | AWAT2
Type: gene
Organism: cattle
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Gene
696451 | AWAT2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3045345 | Awat2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34113821 | J:330312
First Author: Sawai M
Year: 2021
Journal: iScience
Title: Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface.
Volume: 24
Issue: 5
Pages: 102478
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Publication
39414024 | J:359571
 
First Author: Hisey EA
Year: 2024
Journal: Ocul Surf
Title: Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease.
Volume: 34
Pages: 489-503
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Publication
28096191 | J:240457
First Author: Arne JM
Year: 2017
Journal: J Lipid Res
Title: Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2.
Volume: 58
Issue: 4
Pages: 719-730
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Publication
39127389 | J:360168
 
First Author: Puentes B
Year: 2024
Journal: Ocul Surf
Title: Development and validation of a method to generate phenol red thread tests.
Volume: 34
Pages: 262-266
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Publication
32851726 | J:308387
First Author: Widjaja-Adhi MAK
Year: 2020
Journal: FASEB J
Title: Deficiency in Acyl-CoA:Wax Alcohol Acyltransferase 2 causes evaporative dry eye disease by abolishing biosynthesis of wax esters.
Volume: 34
Issue: 10
Pages: 13792-13808
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Publication
35665537 | J:344955
First Author: Widjaja-Adhi MAK
Year: 2022
Journal: FASEB J
Title: Acyl-CoA:wax alcohol acyltransferase 2 modulates the cone visual cycle in mouse retina.
Volume: 36
Issue: 7
Pages: e22390
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Protein Coding Gene
MGP_CAROLIEiJ_G0033266 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035616 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3045345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035745 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035683 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035835 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034602 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031804 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034430 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15220349 | J:92651
First Author: Cheng JB
Year: 2004
Journal: J Biol Chem
Title: Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.
Volume: 279
Issue: 36
Pages: 37798-807
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
28420705 | J:242694
First Author: Ma Z
Year: 2017
Journal: J Lipid Res
Title: Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases.
Volume: 58
Issue: 6
Pages: 1091-1099
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Protein
A2ADU9
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
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Protein
Q80W94
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q9DCV3
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
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Protein
A2ADU8
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: false
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Publication
24799687 | -
First Author: Kaylor JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT).
Volume: 111
Issue: 20
Pages: 7302-7
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Protein
Q6E1M8
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
Q91ZV4
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
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Protein
A2ADU0
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
D3YZB8
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
D3YW64
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
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Protein
D3Z6K9
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: true
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Protein
A0A140LHF3
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
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Protein
Q3V4B0
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
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Publication
11751830 | -
First Author: Sorger D
Year: 2002
Journal: J Bacteriol
Title: Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae.
Volume: 184
Issue: 2
Pages: 519-24
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Publication
11751875 | -
First Author: Oelkers P
Year: 2002
Journal: J Biol Chem
Title: The DGA1 gene determines a second triglyceride synthetic pathway in yeast.
Volume: 277
Issue: 11
Pages: 8877-81
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Publication
26990381 | -
First Author: Meyers A
Year: 2016
Journal: Traffic
Title: Lipid Droplets Form from Distinct Regions of the Cell in the Fission Yeast Schizosaccharomyces pombe.
Volume: 17
Issue: 6
Pages: 657-69
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Publication
27184406 | -
First Author: Brandt C
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Biochemical characterization of human acyl coenzyme A: 2-monoacylglycerol acyltransferase-3 (MGAT3).
Volume: 475
Issue: 3
Pages: 264-70
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Publication
15671038 | -
First Author: Turkish AR
Year: 2005
Journal: J Biol Chem
Title: Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.
Volume: 280
Issue: 15
Pages: 14755-64
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Publication
22623494 | -
First Author: Lippold F
Year: 2012
Journal: Plant Cell
Title: Fatty acid phytyl ester synthesis in chloroplasts of Arabidopsis.
Volume: 24
Issue: 5
Pages: 2001-14
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Protein Domain
IPR007130 | DAGAT
Type: Family
Description: This family includes diacylglycerol acyltransferases which catalyse the terminal and only committed step in triacylglycerol (TAG) synthesis using diacylglycerol (DAG) and fatty acyl-CoA as substrates. It is required for synthesis and storage of intracellular triglycerides [, , , , ]. In yeast, it is involved in lipid particle synthesis from the endoplasmic reticulum, promoting localized TAG production at discrete ER subdomains, and in ergosterol biosynthesis [, ].This family also includes Acyl-CoA wax alcohol acyltransferase 1 and 2 (AWAT1/2), which catalyse the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters [, ]. AWAT2 (also known as MFAT) also possesses acyl-CoA retinol acyltransferase (ARAT) activity that catalyses 11-cis-specific retinyl ester synthesis and shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13-cis-retinol, and all-trans-retinol substrates [].Phytyl ester synthase 1/2, chloroplastic, an acyltransferase involved in fatty acid phytyl ester synthesis in chloroplasts, also belongs to this family. This process is required for the maintenance of the photosynthetic membrane integrity during abiotic stress and senescence [].
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Publication
12963726 | -
First Author: Zhang Q
Year: 2003
Journal: J Biol Chem
Title: Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase.
Volume: 278
Issue: 47
Pages: 47145-55
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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