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Search results 1 to 100 out of 148 for Bag6

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Hits by Category

Hits by Strain

Type Details Score
Gene
7917 | BAG6
Type: gene
Organism: human
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Gene
100038304 | bag6
Type: gene
Organism: frog, western clawed
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Gene
94342 | Bag6
Type: gene
Organism: rat
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Gene
474842 | BAG6
Type: gene
Organism: dog, domestic
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Gene
462560 | BAG6
Type: gene
Organism: chimpanzee
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Gene
508605 | BAG6
Type: gene
Organism: cattle
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Gene
83910 | bag6
Type: gene
Organism: zebrafish
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Gene
720485 | BAG6
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR021925 | BAG6
Type: Domain
Description: This domain is found in large proline-rich protein BAG6 protein. It has a conserved SDL sequence motif. Human BAG6 is an ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins []. It functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation [, , , ].
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Protein Coding Gene
MGI:1919439 | Bag6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
G3UYQ2
Organism: Mus musculus/domesticus
Length: 1082  
Fragment?: false
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Protein
G3UXT8
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: true
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Protein
Q8HWH4
Organism: Mus musculus/domesticus
Length: 522  
Fragment?: true
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Protein
Q3TDL4
Organism: Mus musculus/domesticus
Length: 1108  
Fragment?: true
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Protein
Q9Z1R2
Organism: Mus musculus/domesticus
Length: 1154  
Fragment?: false
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Protein
A0A1B0GX81
Organism: Mus musculus/domesticus
Length: 1107  
Fragment?: true
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Protein
G3UZT6
Organism: Mus musculus/domesticus
Length: 1122  
Fragment?: false
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Protein
Q3UF95
Organism: Mus musculus/domesticus
Length: 1136  
Fragment?: false
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Publication
20516149 | -
First Author: Leznicki P
Year: 2010
Journal: J Cell Sci
Title: Bat3 promotes the membrane integration of tail-anchored proteins.
Volume: 123
Issue: Pt 13
Pages: 2170-8
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Publication
25535373 | J:320131
First Author: Mock JY
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
Volume: 112
Issue: 1
Pages: 106-11
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Publication
21636303 | -
First Author: Wang Q
Year: 2011
Journal: Mol Cell
Title: A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation.
Volume: 42
Issue: 6
Pages: 758-70
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Publication
21743475 | -
First Author: Hessa T
Year: 2011
Journal: Nature
Title: Protein targeting and degradation are coupled for elimination of mislocalized proteins.
Volume: 475
Issue: 7356
Pages: 394-7
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Publication
28104892 | -
First Author: Shao S
Year: 2017
Journal: Science
Title: Mechanistic basis for a molecular triage reaction.
Volume: 355
Issue: 6322
Pages: 298-302
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Publication
32991875 | J:301217
First Author: Xu J
Year: 2020
Journal: Exp Cell Res
Title: The cleft palate candidate gene BAG6 supports FoxO1 acetylation to promote FasL-mediated apoptosis during palate fusion.
Volume: 396
Issue: 2
Pages: 112310
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GXD Expression
GXD Expression
   
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1736321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6507424
Age: embryonic day 13.5
Note: Expression barely detectable in medial edge epithelium (MEE) cells.
Specimen Label: 1A Bag6 E13.5
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1736323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507424
Age: embryonic day 15.5
Note: Expression barely detectable in medial edge epithelium (MEE) cells.
Specimen Label: 1A Bag6 E15.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6507424
Age: embryonic day 14.5
Note: Expression easily detectable in medial edge epithelium.
Specimen Label: 1A Bag6 E14.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6507424
Age: embryonic day 13.5
Note: Expression localizes within medial edge epithelium (MEE) cell nuclei from E13.5 to E15.5.
Specimen Label: 5D Bag6 E13.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6507424
Age: embryonic day 14.5
Note: Expression localizes within medial edge epithelium (MEE) cell nuclei from E13.5 to E15.5.
Specimen Label: 5D Bag6 E14.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6507420
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507424
Age: embryonic day 15.5
Note: Expression localizes within medial edge epithelium (MEE) cell nuclei from E13.5 to E15.5.
Specimen Label: 5D Bag6 E15.5
Detected: true
Specimen Num: 6
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Publication
17403783 | J:120375
First Author: Sasaki T
Year: 2007
Journal: Genes Dev
Title: HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53.
Volume: 21
Issue: 7
Pages: 848-61
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Publication
20713601 | J:168161
First Author: Minami R
Year: 2010
Journal: J Cell Biol
Title: BAG-6 is essential for selective elimination of defective proteasomal substrates.
Volume: 190
Issue: 4
Pages: 637-50
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Publication
18678708 | J:139505
First Author: Sasaki T
Year: 2008
Journal: J Cell Biol
Title: Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis.
Volume: 182
Issue: 3
Pages: 449-58
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Publication
18056262 | J:131590
First Author: Desmots F
Year: 2008
Journal: J Biol Chem
Title: Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis.
Volume: 283
Issue: 6
Pages: 3264-71
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Publication
16287848 | J:119857
First Author: Desmots F
Year: 2005
Journal: Mol Cell Biol
Title: The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development.
Volume: 25
Issue: 23
Pages: 10329-37
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Protein Coding Gene
MGP_CAROLIEiJ_G0021509 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023589 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023456 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024073 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020504 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022414 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10390159 | J:55895
First Author: Ozaki T
Year: 1999
Journal: DNA Cell Biol
Title: Cloning and characterization of rat BAT3 cDNA.
Volume: 18
Issue: 6
Pages: 503-12
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Publication
7854331 | J:20715
First Author: Wang R
Year: 1994
Journal: Mol Cell Biochem
Title: The human BAT3 ortholog in rodents is predominantly and developmentally expressed in testis.
Volume: 136
Issue: 1
Pages: 49-57
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Publication
18487607 | J:138657
First Author: Kwak JH
Year: 2008
Journal: J Biol Chem
Title: BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells.
Volume: 283
Issue: 28
Pages: 19816-25
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GXD Expression
GXD Expression
     
Probe: MGI:6507422
Assay Type: RT-PCR
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Stage: TS21
Assay Id: MGI:6507427
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6507422
Assay Type: RT-PCR
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6507427
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6507422
Assay Type: RT-PCR
Annotation Date: 2021-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736323
Stage: TS23
Assay Id: MGI:6507427
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 3
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Publication
18765639 | J:141177
First Author: Nguyen P
Year: 2008
Journal: Mol Cell Biol
Title: BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression.
Volume: 28
Issue: 21
Pages: 6720-9
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Publication
9851834 | J:51531
First Author: Ohashi T
Year: 1998
Journal: Arch Biochem Biophys
Title: Oligomeric structure and tissue distribution of ficolins from mouse, pig and human.
Volume: 360
Issue: 2
Pages: 223-32
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Publication
10773876 | J:61772
First Author: Xu X
Year: 2000
Journal: Oncogene
Title: Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.
Volume: 19
Issue: 15
Pages: 1868-74
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Publication
24591579 | J:207394
First Author: Sebti S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.
Volume: 111
Issue: 11
Pages: 4115-20
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Publication
11063033 | J:51772
First Author: Paine CT
Year: 1998
Journal: Connect Tissue Res
Title: Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system.
Volume: 38
Issue: 1-4
Pages: 257-67;discussion 295-303
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Publication
21460186 | J:182961
First Author: Kaczmarek K
Year: 2011
Journal: Mol Biol Cell
Title: Overexpression of peroxisomal testis-specific 1 protein induces germ cell apoptosis and leads to infertility in male mice.
Volume: 22
Issue: 10
Pages: 1766-79
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Publication
9196000 | J:41366
First Author: Lanning D
Year: 1997
Journal: Mamm Genome
Title: Localization of the casein kinase II beta-subunit gene within the mouse H-2 complex class III region and comparison of expression with Bat genes.
Volume: 8
Issue: 7
Pages: 519-21
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Publication
1351875 | J:1314
First Author: Lafuse WP
Year: 1992
Journal: Immunogenetics
Title: PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex.
Volume: 36
Issue: 2
Pages: 110-6
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Publication
9021146 | J:38062
First Author: Dagenais SL
Year: 1997
Journal: Mamm Genome
Title: A physical map of the mouse H2 Bat5/Db interval.
Volume: 8
Issue: 1
Pages: 39-41
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Publication
26692333 | J:233169
First Author: Osorio FG
Year: 2016
Journal: Nat Med
Title: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
Volume: 22
Issue: 1
Pages: 91-6
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Publication
7993390 | J:15971
First Author: Gasser DL
Year: 1994
Journal: Immunogenetics
Title: P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci.
Volume: 39
Issue: 1
Pages: 48-55
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Publication
10469308 | J:56747
First Author: Handel-Fernandez ME
Year: 1999
Journal: J Invest Dermatol
Title: Genetic mapping and physical cloning of UVB susceptibility region in mice.
Volume: 113
Issue: 2
Pages: 224-9
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Publication
27739607 | J:301847
First Author: Ni L
Year: 2016
Journal: Mol Reprod Dev
Title: Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.
Volume: 83
Issue: 12
Pages: 1060-1069
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Publication
28380258 | J:309653
First Author: Tong Y
Year: 2017
Journal: FEBS Lett
Title: An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome.
Volume: 591
Issue: 9
Pages: 1247-1257
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Publication
10871872 | J:63110
First Author: Allcock RJ
Year: 2000
Journal: Immunol Today
Title: The mouse as a model for the effects of MHC genes on human disease.
Volume: 21
Issue: 7
Pages: 328-32
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Publication
12819136 | J:84168
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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