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Search results 1 to 100 out of 591 for Bcl2l11

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
10018 | BCL2L11
Type: gene
Organism: human
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Gene
613103 | bcl2l11
Type: gene
Organism: frog, western clawed
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Gene
107052854 | BCL2L11
Type: gene
Organism: chicken
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Gene
64547 | Bcl2l11
Type: gene
Organism: rat
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Gene
612867 | BCL2L11
Type: gene
Organism: dog, domestic
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Gene
459487 | BCL2L11
Type: gene
Organism: chimpanzee
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Gene
507390 | BCL2L11
Type: gene
Organism: cattle
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Gene
100190951 | bcl2l11
Type: gene
Organism: zebrafish
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Gene
697082 | BCL2L11
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1197519 | Bcl2l11
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33087587 | J:325261
First Author: Li J
Year: 2020
Journal: Aging (Albany NY)
Title: MicroRNA-338-5p alleviates neuronal apoptosis via directly targeting BCL2L11 in APP/PS1 mice.
Volume: 12
Issue: 20
Pages: 20728-20742
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Publication
27525555 | J:236609
First Author: Kotzin JJ
Year: 2016
Journal: Nature
Title: The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.
Volume: 537
Issue: 7619
Pages: 239-243
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189857
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Bcl2l11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189857
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Bcl2l11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189857
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Bcl2l11
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189857
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Bcl2l11
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189857
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Bcl2l11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189857
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Bcl2l11
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6168437
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189857
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Bcl2l11
Detected: true
Specimen Num: 7
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Publication
32579941 | J:300229
First Author: Cai Z
Year: 2020
Journal: Cell Rep
Title: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Volume: 31
Issue: 12
Pages: 107816
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Publication
21151127 | J:169033
First Author: Melum E
Year: 2011
Journal: Nat Genet
Title: Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
Volume: 43
Issue: 1
Pages: 17-9
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Protein
Q6PEB3
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: false
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Publication
30301924 | J:318662
First Author: Leidy-Davis T
Year: 2018
Journal: Sci Rep
Title: Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches.
Volume: 8
Issue: 1
Pages: 15028
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Publication
33086067 | J:301233
First Author: Goh W
Year: 2020
Journal: Cell Rep
Title: Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance.
Volume: 33
Issue: 3
Pages: 108285
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Publication
32082327 | J:305758
 
First Author: Delconte RB
Year: 2020
Journal: Front Immunol
Title: NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS.
Volume: 11
Pages: 75
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Publication
20708584 | J:163670
First Author: Spruce T
Year: 2010
Journal: Dev Cell
Title: An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.
Volume: 19
Issue: 2
Pages: 207-19
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Publication
21858169 | J:176360
First Author: Chuang PY
Year: 2011
Journal: PLoS One
Title: Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus.
Volume: 6
Issue: 8
Pages: e23566
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Publication
26438731 | J:273075
 
First Author: Phua YL
Year: 2015
Journal: Physiol Rep
Title: Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Volume: 3
Issue: 10
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Protein Coding Gene
MGP_CAROLIEiJ_G0024269 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1197519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025651 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026288 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025714 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025189 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
32868930 | J:306374
First Author: Burrows N
Year: 2020
Journal: Nat Immunol
Title: Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.
Volume: 21
Issue: 11
Pages: 1408-1420
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Publication
10576740 | J:58641
First Author: Bouillet P
Year: 1999
Journal: Science
Title: Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.
Volume: 286
Issue: 5445
Pages: 1735-8
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Publication
21734077 | J:179168
First Author: Fox AC
Year: 2011
Journal: J Immunol
Title: Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality.
Volume: 187
Issue: 4
Pages: 1950-6
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Publication
16782750 | J:121209
First Author: Pierce J
Year: 2006
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia.
Volume: 291
Issue: 5
Pages: L862-70
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Publication
19815516 | J:153744
First Author: Tsukamoto H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects.
Volume: 106
Issue: 43
Pages: 18333-8
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Publication
17585338 | J:141495
First Author: Bauer A
Year: 2007
Journal: Cell Death Differ
Title: Inhibition of apoptosis can be accompanied by increased Bim levels in T lymphocytes and neutrophil granulocytes.
Volume: 14
Issue: 9
Pages: 1714-6
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Publication
17312102 | J:144121
First Author: Goodyear CS
Year: 2007
Journal: J Immunol
Title: Cutting Edge: Bim is required for superantigen-mediated B cell death.
Volume: 178
Issue: 5
Pages: 2636-40
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Publication
23668821 | J:200626
First Author: Leucht K
Year: 2013
Journal: Clin Exp Immunol
Title: Impaired removal of Vβ8(+) lymphocytes aggravates colitis in mice deficient for B cell lymphoma-2-interacting mediator of cell death (Bim).
Volume: 173
Issue: 3
Pages: 493-501
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Publication
21047504 | J:168031
First Author: Wang S
Year: 2011
Journal: Dev Biol
Title: Bim is responsible for the inherent sensitivity of the developing retinal vasculature to hyperoxia.
Volume: 349
Issue: 2
Pages: 296-309
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Publication
22156338 | J:180886
First Author: Lauer C
Year: 2012
Journal: J Immunol
Title: The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis.
Volume: 188
Issue: 2
Pages: 916-22
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Publication
22240894 | J:203181
First Author: Clybouw C
Year: 2012
Journal: Cell Death Differ
Title: Alternative splicing of Bim and Erk-mediated Bim(EL) phosphorylation are dispensable for hematopoietic homeostasis in vivo.
Volume: 19
Issue: 6
Pages: 1060-8
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Publication
31813995 | J:285797
First Author: Roberts SL
Year: 2020
Journal: Hum Mol Genet
Title: Bim contributes to the progression of Huntington's disease-associated phenotypes.
Volume: 29
Issue: 2
Pages: 216-227
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Publication
23869083 | J:202232
First Author: Cippà PE
Year: 2013
Journal: Blood
Title: Targeting apoptosis to induce stable mixed hematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice.
Volume: 122
Issue: 9
Pages: 1669-77
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Publication
16520387 | J:123717
First Author: Oliver PM
Year: 2006
Journal: J Exp Med
Title: Loss of the proapoptotic protein, Bim, breaks B cell anergy.
Volume: 203
Issue: 3
Pages: 731-41
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Publication
23644507 | J:259369
First Author: Mingueneau M
Year: 2013
Journal: Nat Immunol
Title: The transcriptional landscape of αβ T cell differentiation.
Volume: 14
Issue: 6
Pages: 619-32
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Publication
19933852 | J:157488
First Author: Hu Q
Year: 2009
Journal: J Immunol
Title: Bim-mediated apoptosis is not necessary for thymic negative selection to ubiquitous self-antigens.
Volume: 183
Issue: 12
Pages: 7761-7
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Publication
15592435 | J:106372
First Author: Alfredsson J
Year: 2005
Journal: Cell Death Differ
Title: Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation.
Volume: 12
Issue: 2
Pages: 136-44
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Publication
27371614 | J:249850
First Author: Overall SA
Year: 2016
Journal: Int Immunol
Title: Rapamycin results in Bim-mediated loss of thymic regulatory T cells during development in organ culture.
Volume: 28
Issue: 10
Pages: 513-518
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Publication
27869196 | J:243074
 
First Author: Marchingo JM
Year: 2016
Journal: Nat Commun
Title: T-cell stimuli independently sum to regulate an inherited clonal division fate.
Volume: 7
Pages: 13540
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Publication
19411758 | J:150453
First Author: Ludwinski MW
Year: 2009
Journal: J Clin Invest
Title: Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice.
Volume: 119
Issue: 6
Pages: 1706-13
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Publication
19407828 | J:164177
First Author: Andina N
Year: 2009
Journal: Cell Death Differ
Title: Induction of Bim limits cytokine-mediated prolonged survival of neutrophils.
Volume: 16
Issue: 9
Pages: 1248-55
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Publication
27302161 | J:234836
First Author: Hettich M
Year: 2016
Journal: Cancer Res
Title: Checkpoint Antibodies but not T Cell-Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation.
Volume: 76
Issue: 16
Pages: 4673-83
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Publication
18086806 | J:131639
First Author: Reckling S
Year: 2008
Journal: Infect Immun
Title: Proapoptotic Bcl-2 family member Bim promotes persistent infection and limits protective immunity.
Volume: 76
Issue: 3
Pages: 1179-85
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Publication
29053141 | J:271923
First Author: Wali JA
Year: 2018
Journal: Cell Death Differ
Title: Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.
Volume: 25
Issue: 1
Pages: 217-225
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Publication
19779495 | J:169433
First Author: Murphy BM
Year: 2010
Journal: Cell Death Differ
Title: Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.
Volume: 17
Issue: 3
Pages: 459-68
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Publication
20570860 | J:165889
First Author: Richter-Larrea JA
Year: 2010
Journal: Blood
Title: Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.
Volume: 116
Issue: 14
Pages: 2531-42
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Publication
20844198 | J:164881
First Author: Tsukamoto H
Year: 2010
Journal: J Immunol
Title: Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects.
Volume: 185
Issue: 8
Pages: 4535-44
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Publication
14517273 | J:86002
First Author: Enders A
Year: 2003
Journal: J Exp Med
Title: Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells.
Volume: 198
Issue: 7
Pages: 1119-26
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Publication
22760702 | J:187928
First Author: Williams EL
Year: 2012
Journal: Eur J Immunol
Title: Development and characterisation of monoclonal antibodies specific for the murine inhibitory FcγRIIB (CD32B).
Volume: 42
Issue: 8
Pages: 2109-20
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Publication
17913922 | J:125591
First Author: Doonan F
Year: 2007
Journal: J Neurosci
Title: Bim expression indicates the pathway to retinal cell death in development and degeneration.
Volume: 27
Issue: 40
Pages: 10887-94
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Publication
22117046 | J:181783
First Author: He S
Year: 2012
Journal: Blood
Title: Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
Volume: 119
Issue: 5
Pages: 1274-82
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Publication
16761315 | J:115833
First Author: Wojciechowski S
Year: 2006
Journal: Eur J Immunol
Title: Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory.
Volume: 36
Issue: 7
Pages: 1694-706
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Publication
23577147 | J:199935
First Author: Miller AV
Year: 2013
Journal: PLoS One
Title: Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.
Volume: 8
Issue: 4
Pages: e60685
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Publication
22215602 | J:179928
First Author: Suen AY
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.
Volume: 109
Issue: 3
Pages: 893-8
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Publication
15589170 | J:94684
First Author: Liston A
Year: 2004
Journal: Immunity
Title: Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.
Volume: 21
Issue: 6
Pages: 817-30
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Publication
28552963 | J:246010
First Author: Wang S
Year: 2017
Journal: PLoS One
Title: Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature.
Volume: 12
Issue: 5
Pages: e0178198
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Publication
23840678 | J:225051
First Author: Jay DC
Year: 2013
Journal: PLoS One
Title: Bim mediates the elimination of functionally unfit Th1 responders from the memory pool.
Volume: 8
Issue: 6
Pages: e67363
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Publication
18619445 | J:141863
First Author: Holz LE
Year: 2008
Journal: Gastroenterology
Title: Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death.
Volume: 135
Issue: 3
Pages: 989-97
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Publication
28928277 | J:253489
First Author: Litwak SA
Year: 2017
Journal: Diabetes
Title: JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.
Volume: 66
Issue: 12
Pages: 2973-2986
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Publication
19293378 | J:248251
First Author: Desbien AL
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim.
Volume: 106
Issue: 14
Pages: 5663-8
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Publication
11210187 | J:69112
First Author: Bouillet P
Year: 2001
Journal: Mamm Genome
Title: Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim.
Volume: 12
Issue: 2
Pages: 163-8
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Publication
12749905 | J:83490
First Author: Seward RJ
Year: 2003
Journal: Mol Immunol
Title: Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis.
Volume: 39
Issue: 16
Pages: 983-93
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Publication
15292207 | J:93457
First Author: Wang P
Year: 2004
Journal: J Biol Chem
Title: Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins.
Volume: 279
Issue: 40
Pages: 41280-5
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Publication
15634885 | J:95841
First Author: Kirschnek S
Year: 2005
Journal: J Immunol
Title: Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim.
Volume: 174
Issue: 2
Pages: 671-9
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Publication
16034091 | J:107290
First Author: Bunin A
Year: 2005
Journal: J Immunol
Title: Regulation of Bim by TCR signals in CD4/CD8 double-positive thymocytes.
Volume: 175
Issue: 3
Pages: 1532-9
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Publication
17559169 | J:123493
First Author: Hamrouni A
Year: 2007
Journal: Eur J Immunol
Title: Impact of cellular lifespan on the T cell receptor repertoire.
Volume: 37
Issue: 7
Pages: 1978-85
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Publication
18292495 | J:131729
First Author: Barron L
Year: 2008
Journal: J Immunol
Title: Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance.
Volume: 180
Issue: 5
Pages: 2762-6
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Publication
19805519 | J:154986
First Author: Chen S
Year: 2009
Journal: Mol Cell Biol
Title: Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
Volume: 29
Issue: 23
Pages: 6149-69
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Publication
22301689 | J:184089
First Author: Gao Y
Year: 2012
Journal: Int Immunol
Title: Bim regulates B-cell receptor-mediated apoptosis in the presence of CD40 signaling in CD40-pre-activated splenic B cells differentiating into plasma cells.
Volume: 24
Issue: 5
Pages: 283-92
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Publication
24663676 | J:209985
First Author: Iyoda T
Year: 2014
Journal: J Immunol
Title: A novel mechanism underlying the basic defensive response of macrophages against Mycobacterium infection.
Volume: 192
Issue: 9
Pages: 4254-62
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Publication
29114065 | J:251967
First Author: Tsai F
Year: 2017
Journal: J Exp Med
Title: Bim suppresses the development of SLE by limiting myeloid inflammatory responses.
Volume: 214
Issue: 12
Pages: 3753-3773
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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