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Search results 1 to 90 out of 90 for Bend3

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Hits by Category

Hits by Strain

Type Details Score
Gene
57673 | BEND3
Type: gene
Organism: human
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Gene
100490658 | bend3
Type: gene
Organism: frog, western clawed
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Gene
481949 | BEND3
Type: gene
Organism: dog, domestic
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Gene
472087 | BEND3
Type: gene
Organism: chimpanzee
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Gene
683923 | Bend3
Type: gene
Organism: rat
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Gene
525371 | BEND3
Type: gene
Organism: cattle
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Gene
421778 | BEND3
Type: gene
Organism: chicken
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Gene
565716 | bend3
Type: gene
Organism: zebrafish
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Gene
703032 | BEND3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2677212 | Bend3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033583 | BEND3
Type: Family
Description: BEND3 is a transcriptional repressor that associates with the nucleolar-remodeling complex (NoRC) and is involved in ribosomal DNA (rDNA) silencing []. SUMOylated BEND3 stabilizes the NoRC component Tip5 via USP21 deubiquitinase []. NorC serves as a molecular platform that recruits chromatin modifiers, such as histone deacetylases and histone methyltransferases, leading to deacetylation of histone H4 and trimethylation of H3K9 and H4K20 []. NoRC also targets histone deacetylases and histone methyltransferases to rDNA to establish a heterochromatic state that inhibits transcription activation. Hence, BEND3 and NoRC seem to play a concerted role in the maintenance of heterochromatin architecture [, ].BEND3 has also been shown to mediate Polycomb recruitment in the absence of H3K9Me3 or DNA methylation at the pericentromeric regions []. BEND3 interacts with PICH (ERCC6L), a DNA translocase required for the maintenance of chromosome stability, and stimulates its translocase and ATPase activities. This interaction occurs via an interface between a TPR domain in PICH and a BEN domain in BEND3 [].
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GXD Expression
GXD Expression
 
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:361197
Stage: TS07
Assay Id: MGI:7639750
Age: embryonic day 5.5
Image: S5c BEND3
Note: Expression lost at E5.5.
Specimen Label: S5c BEND3
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7639750
Age: embryonic day 3.5
Image: S5a BEND3
Specimen Label: S5a BEND3
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:7639750
Age: embryonic day 4.0
Image: S5b BEND3
Note: Expression conserved up to E5.0 in all cells.
Specimen Label: S5b BEND3
Detected: true
Specimen Num: 9
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Publication
26507581 | -
First Author: Khan A
Year: 2015
Journal: Transcription
Title: BEND3 mediates transcriptional repression and heterochromatin organization.
Volume: 6
Issue: 5
Pages: 102-5
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Publication
35143257 | J:320655
   
First Author: Zhang J
Year: 2022
Journal: Science
Title: Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation.
Pages: eabm0730
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Publication
25457167 | -
First Author: Saksouk N
Year: 2014
Journal: Mol Cell
Title: Redundant mechanisms to form silent chromatin at pericentromeric regions rely on BEND3 and DNA methylation.
Volume: 56
Issue: 4
Pages: 580-94
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Publication
26100909 | -
First Author: Khan A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase.
Volume: 112
Issue: 27
Pages: 8338-43
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Publication
37650637 | J:349241
First Author: Yakhou L
Year: 2023
Journal: Nucleic Acids Res
Title: A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation.
Volume: 51
Issue: 19
Pages: 10292-10308
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Protein
A0A1L1SSB5
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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Protein
A0A1L1SU50
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Publication
21914818 | -
First Author: Sathyan KM
Year: 2011
Journal: J Cell Sci
Title: A BEN-domain-containing protein associates with heterochromatin and represses transcription.
Volume: 124
Issue: Pt 18
Pages: 3149-63
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Publication
28977671 | -
First Author: Pitchai GP
Year: 2017
Journal: Nucleic Acids Res
Title: A novel TPR-BEN domain interaction mediates PICH-BEND3 association.
Volume: 45
Issue: 19
Pages: 11413-11424
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Protein
Q6PAL0
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0015287 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017130 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2677212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016532 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017057 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030705 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016096 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:361197
Stage: TS07
Assay Id: MGI:7639750
Age: embryonic day 5.5
Image: 5g E5.5
Note: Expression lost at E5.5.
Specimen Label: 5g E5.5
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:7639750
Age: embryonic day 2.0
Image: 5e 4-cell
Specimen Label: 5e 4-cell
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:7639750
Age: embryonic day 2.5
Image: 5e 8-cell
Note: Expression enriched at pericentromeric heterochromatin starting at 8-cell stage.
Specimen Label: 5e 8-cell
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7639750
Age: embryonic day 3.5
Image: 5g E3.5
Specimen Label: 5g E3.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:7639750
Age: embryonic day 4.0
Image: 5g E4.0
Note: Expression conserved up to E5.0 in all cells.
Specimen Label: 5g E4.0
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:7639750
Age: embryonic day 3.0
Image: 5e 16-cell
Specimen Label: 5e 16-cell
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7639736
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:7639750
Age: embryonic day 1.0
Image: 5e 2-cell
Specimen Label: 5e 2-cell
Detected: false
Specimen Num: 1
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Publication
35974030 | J:327416
First Author: Pailles M
Year: 2022
Journal: Sci Rep
Title: H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst.
Volume: 12
Issue: 1
Pages: 13908
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31271645 | J:282046
First Author: Liu F
Year: 2019
Journal: FEBS Lett
Title: Erg mediates downregulation of claudin-5 in the brain endothelium of a murine experimental model of cerebral malaria.
Volume: 593
Issue: 18
Pages: 2585-2595
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Publication
21808008 | J:175609
First Author: Suzuki K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function.
Volume: 108
Issue: 33
Pages: 13829-34
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Publication
8562500 | J:125139
First Author: Aigner S
Year: 1995
Journal: Int Immunol
Title: Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin.
Volume: 7
Issue: 10
Pages: 1557-65
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Publication
7524641 | J:19833
First Author: Sammar M
Year: 1994
Journal: Int Immunol
Title: Heat-stable antigen (CD24) as ligand for mouse P-selectin.
Volume: 6
Issue: 7
Pages: 1027-36
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Publication
22378877 | J:182688
First Author: Liu J
Year: 2012
Journal: J Neurosci
Title: Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage.
Volume: 32
Issue: 9
Pages: 3044-57
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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