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Search results 1 to 100 out of 565 for Bid

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Hits by Strain

Type Details Score
Gene
637 | BID
Type: gene
Organism: human
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Gene
100036674 | bid
Type: gene
Organism: frog, western clawed
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Gene
64625 | Bid
Type: gene
Organism: rat
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Gene
458635 | BID
Type: gene
Organism: chimpanzee
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Gene
510373 | BID
Type: gene
Organism: cattle
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Gene
100683675 | BID
Type: gene
Organism: dog, domestic
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Gene
395236 | BID
Type: gene
Organism: chicken
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Gene
100426724 | BID
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR010479 | BID
Type: Family
Description: Bcl-2 proteins are central regulators of caspase activation, and play a key role in cell death by regulating the integrity of the mitochondrial and endoplasmic reticulum (ER) membranes []. At least 20 Bcl-2 proteins have been reported in mammals, and several others have been identified in viruses. Bcl-2 family proteins fall roughly into three subtypes, which either promote cell survival (anti-apoptotic) or trigger cell death (pro-apoptotic). All members contain at least one of four conserved motifs, termed Bcl-2 Homology (BH) domains. Bcl-2 subfamily proteins, which contain at least BH1 and BH2, promote cell survival by inhibiting the adapters needed for the activation of caspases.Pro-apoptotic members potentially exert their effects by displacing the adapters from the pro-survival proteins; these proteins belong either to the Bax subfamily, which contain BH1-BH3, or to the BH3 subfamily, which mostly only feature BH3 []. Thus, the balance between antagonistic family members is believed to play a role in determining cell fate. Members of the wider Bcl-2 family, which also includes Bcl-x, Bcl-w and Mcl-1, are described by their similarity to Bcl-2 protein, a member of the pro-survival Bcl-2 subfamily []. Full-length Bcl-2 proteins feature all four BH domains, seven α-helices, and a C-terminal hydrophobic motif that targets the protein to the outer mitochondrial membrane, ER and nuclear envelope. BID is a member of the Bcl-2 superfamily of proteins that are key regulators of programmed cell death, hence this family is related to the Apoptosis regulator Bcl-2 protein BH domain. BID is a pro-apoptotic member of the Bcl-2 superfamily and as such posses the ability to target intracellular membranes and contains the BH3 death domain. The activity of BID is regulated by a Caspase 8-mediated cleavage event, exposing the BH3 domain and significantly changing the surface charge and hydrophobicity, which causes a change of cellular localisation [].
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Protein Coding Gene
MGI:108093 | Bid
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P70444
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
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Publication
11412905 | J:71150
First Author: Leonard JR
Year: 2001
Journal: Brain Res Dev Brain Res
Title: Bid regulation of neuronal apoptosis.
Volume: 128
Issue: 2
Pages: 187-90
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Publication
22914170 | J:187146
First Author: Nachbur U
Year: 2012
Journal: Nature
Title: Is BID required for NOD signalling?
Volume: 488
Issue: 7412
Pages: E4-6; discussion E6-8
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Publication
21552281 | J:172656
First Author: Yeretssian G
Year: 2011
Journal: Nature
Title: Non-apoptotic role of BID in inflammation and innate immunity.
Volume: 474
Issue: 7349
Pages: 96-9
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Publication
10089878 | -
First Author: McDonnell JM
Year: 1999
Journal: Cell
Title: Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists.
Volume: 96
Issue: 5
Pages: 625-34
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Publication
12402042 | J:80564
First Author: Sax JK
Year: 2002
Journal: Nat Cell Biol
Title: BID regulation by p53 contributes to chemosensitivity.
Volume: 4
Issue: 11
Pages: 842-9
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Publication
16537427 | J:107667
First Author: Budinger GR
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Proapoptotic Bid is required for pulmonary fibrosis.
Volume: 103
Issue: 12
Pages: 4604-9
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Publication
20617182 | J:162998
 
First Author: Danthi P
Year: 2010
Journal: PLoS Pathog
Title: Bid regulates the pathogenesis of neurotropic reovirus.
Volume: 6
Pages: e1000980
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Protein
D3Z463
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Strain
MGI:7341864 | BID/MplStud
Attribute String: inbred strain, wild-derived
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Publication
16122425 | J:101952
First Author: Zinkel SS
Year: 2005
Journal: Cell
Title: A role for proapoptotic BID in the DNA-damage response.
Volume: 122
Issue: 4
Pages: 579-91
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Publication
24956542 | J:215478
 
First Author: König HG
Year: 2014
Journal: Neurobiol Dis
Title: The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes.
Volume: 70
Pages: 99-107
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Publication
9735050 | J:49588
First Author: Adams JM
Year: 1998
Journal: Science
Title: The Bcl-2 protein family: arbiters of cell survival.
Volume: 281
Issue: 5381
Pages: 1322-6
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Publication
12631689 | -
First Author: Germain M
Year: 2003
Journal: Sci STKE
Title: Cellular distribution of Bcl-2 family proteins.
Volume: 2003
Issue: 173
Pages: pe10
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Publication
15574417 | J:96908
First Author: Waterhouse NJ
Year: 2005
Journal: J Biol Chem
Title: A central role for Bid in granzyme B-induced apoptosis.
Volume: 280
Issue: 6
Pages: 4476-82
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Publication
15855651 | J:98464
First Author: Bai L
Year: 2005
Journal: Am J Pathol
Title: Deletion of Bid impedes cell proliferation and hepatic carcinogenesis.
Volume: 166
Issue: 5
Pages: 1523-32
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Publication
22522598 | J:204796
First Author: Liu Y
Year: 2012
Journal: Cell Death Differ
Title: Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress.
Volume: 19
Issue: 10
Pages: 1602-12
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Publication
11714870 | J:78391
First Author: Higuchi H
Year: 2001
Journal: J Pharmacol Exp Ther
Title: Bid antisense attenuates bile acid-induced apoptosis and cholestatic liver injury.
Volume: 299
Issue: 3
Pages: 866-73
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Publication
15148322 | J:91754
First Author: Valentijn AJ
Year: 2004
Journal: J Biol Chem
Title: Translocation of full-length Bid to mitochondria during anoikis.
Volume: 279
Issue: 31
Pages: 32848-57
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Publication
16122426 | J:115186
First Author: Kamer I
Year: 2005
Journal: Cell
Title: Proapoptotic BID is an ATM effector in the DNA-damage response.
Volume: 122
Issue: 4
Pages: 593-603
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Publication
17448999 | J:158191
First Author: Kaufmann T
Year: 2007
Journal: Cell
Title: The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest.
Volume: 129
Issue: 2
Pages: 423-33
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Publication
17052454 | J:114403
First Author: Walensky LD
Year: 2006
Journal: Mol Cell
Title: A stapled BID BH3 helix directly binds and activates BAX.
Volume: 24
Issue: 2
Pages: 199-210
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Publication
16495337 | J:112537
First Author: Bonzon C
Year: 2006
Journal: Mol Biol Cell
Title: Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.
Volume: 17
Issue: 5
Pages: 2150-7
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Publication
17686781 | J:125379
First Author: Huang X
Year: 2007
Journal: J Biol Chem
Title: Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb.
Volume: 282
Issue: 40
Pages: 29401-13
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Publication
21738214 | J:203086
First Author: Cabon L
Year: 2012
Journal: Cell Death Differ
Title: BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation.
Volume: 19
Issue: 2
Pages: 245-56
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Publication
21339359 | J:170848
First Author: Masson F
Year: 2011
Journal: J Immunol
Title: Bid and Bim collaborate during induction of T cell death in persistent infection.
Volume: 186
Issue: 7
Pages: 4059-66
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Publication
21113148 | J:186973
First Author: Liu Y
Year: 2011
Journal: Cell Death Differ
Title: Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress.
Volume: 18
Issue: 5
Pages: 841-52
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Publication
12533511 | J:81329
First Author: Zinkel SS
Year: 2003
Journal: Genes Dev
Title: Proapoptotic BID is required for myeloid homeostasis and tumor suppression.
Volume: 17
Issue: 2
Pages: 229-39
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Publication
19380821 | J:147707
First Author: Maret M
Year: 2009
Journal: J Immunol
Title: A role for Bid in eosinophil apoptosis and in allergic airway reaction.
Volume: 182
Issue: 9
Pages: 5740-7
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Publication
9727492 | J:49460
First Author: Li H
Year: 1998
Journal: Cell
Title: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.
Volume: 94
Issue: 4
Pages: 491-501
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Publication
25909884 | J:258867
First Author: Wree A
Year: 2015
Journal: Cell Death Differ
Title: Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.
Volume: 22
Issue: 12
Pages: 1985-94
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Publication
18252892 | J:135326
First Author: McKenzie MD
Year: 2008
Journal: Diabetes
Title: Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells.
Volume: 57
Issue: 5
Pages: 1284-92
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Publication
21041309 | J:173142
First Author: Du H
Year: 2011
Journal: J Biol Chem
Title: BH3 domains other than Bim and Bid can directly activate Bax/Bak.
Volume: 286
Issue: 1
Pages: 491-501
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Publication
27641306 | J:239131
First Author: Tasdogan A
Year: 2016
Journal: Cell Stem Cell
Title: DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.
Volume: 19
Issue: 6
Pages: 752-767
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Publication
16106037 | J:104086
First Author: Wei Q
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice.
Volume: 290
Issue: 1
Pages: F35-42
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Publication
18713978 | J:138961
First Author: Pradhan S
Year: 2008
Journal: J Immunol
Title: A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosis.
Volume: 181
Issue: 5
Pages: 3077-88
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Publication
11742085 | J:73477
First Author: Plesnila N
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia.
Volume: 98
Issue: 26
Pages: 15318-23
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Publication
21703985 | J:186806
First Author: Shen H
Year: 2011
Journal: Exp Hematol
Title: Bid is a positive regulator for donor-derived lymphoid cell regeneration in γ-irradiated recipients.
Volume: 39
Issue: 9
Pages: 947-957.e1
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Publication
17585339 | J:141357
First Author: Oberkovitz G
Year: 2007
Journal: Cell Death Differ
Title: Nucleocytoplasmic shuttling of BID is involved in regulating its activities in the DNA-damage response.
Volume: 14
Issue: 9
Pages: 1628-34
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Publication
19463967 | J:153471
First Author: Manara A
Year: 2009
Journal: Biochim Biophys Acta
Title: Bid binding to negatively charged phospholipids may not be required for its pro-apoptotic activity in vivo.
Volume: 1791
Issue: 10
Pages: 997-1010
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Publication
29495595 | J:318476
 
First Author: Wicki S
Year: 2018
Journal: Int J Mol Sci
Title: Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss.
Volume: 19
Issue: 3
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Publication
15661737 | J:114122
First Author: Zhai D
Year: 2005
Journal: J Biol Chem
Title: Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak.
Volume: 280
Issue: 16
Pages: 15815-24
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Publication
27257617 | J:240199
 
First Author: Kinsella S
Year: 2016
Journal: eNeuro
Title: Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia.
Volume: 3
Issue: 2
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Publication
25368155 | J:216754
First Author: Leibowitz B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs.
Volume: 111
Issue: 46
Pages: 16520-5
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Publication
23470523 | J:228255
First Author: Biswas S
Year: 2013
Journal: Cell Death Differ
Title: The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- mice.
Volume: 20
Issue: 7
Pages: 869-77
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Publication
19366803 | J:148275
First Author: Hodge DL
Year: 2009
Journal: Cancer Res
Title: Interleukin-15 enhances proteasomal degradation of bid in normal lymphocytes: implications for large granular lymphocyte leukemias.
Volume: 69
Issue: 9
Pages: 3986-94
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Publication
18426910 | J:137299
First Author: Upton JP
Year: 2008
Journal: Mol Cell Biol
Title: Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress.
Volume: 28
Issue: 12
Pages: 3943-51
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Publication
19332555 | J:149146
First Author: Madesh M
Year: 2009
Journal: Mol Cell Biol
Title: Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak.
Volume: 29
Issue: 11
Pages: 3099-112
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Publication
19661444 | J:152902
First Author: Nalapareddy Pd
Year: 2009
Journal: Am J Pathol
Title: The BH3-only protein bid does not mediate death-receptor-induced liver injury in obstructive cholestasis.
Volume: 175
Issue: 3
Pages: 1077-85
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Publication
11867899 | J:112420
First Author: Plesnila N
Year: 2002
Journal: Eur Surg Res
Title: Function of BID -- a molecule of the bcl-2 family -- in ischemic cell death in the brain.
Volume: 34
Issue: 1-2
Pages: 37-41
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Publication
30281024 | J:268835
   
First Author: Salisbury-Ruf CT
Year: 2018
Journal: Elife
Title: Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.
Volume: 7
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Publication
12934064 | J:115694
First Author: Houseweart MK
Year: 2003
Journal: Cell Death Differ
Title: Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1).
Volume: 10
Issue: 12
Pages: 1329-35
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Publication
25951810 | J:317858
First Author: Orlik J
Year: 2015
Journal: Hepatology
Title: The BH3-only protein BID impairs the p38-mediated stress response and promotes hepatocarcinogenesis during chronic liver injury in mice.
Volume: 62
Issue: 3
Pages: 816-28
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Publication
19079139 | J:158076
First Author: Jabbour AM
Year: 2009
Journal: Cell Death Differ
Title: Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.
Volume: 16
Issue: 4
Pages: 555-63
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Publication
19119023 | J:143730
First Author: Kaufmann T
Year: 2009
Journal: Immunity
Title: Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.
Volume: 30
Issue: 1
Pages: 56-66
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Publication
17096024 | J:132334
First Author: Kaufmann T
Year: 2007
Journal: Cell Death Differ
Title: Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction.
Volume: 14
Issue: 3
Pages: 637-9
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Publication
17955375 | J:285867
First Author: Ni HM
Year: 2008
Journal: Apoptosis
Title: The impact of genetic background and Bid on the phenotype of Bcl-2-deficiency in mice.
Volume: 13
Issue: 1
Pages: 53-62
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Publication
22996683 | J:205628
First Author: Harder JM
Year: 2013
Journal: Cell Death Differ
Title: Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death.
Volume: 20
Issue: 1
Pages: 182
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Publication
26997499 | J:251363
First Author: Oettinghaus B
Year: 2016
Journal: Biochim Biophys Acta
Title: DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.
Volume: 1857
Issue: 8
Pages: 1267-1276
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Publication
9873064 | J:169290
First Author: Gross A
Year: 1999
Journal: J Biol Chem
Title: Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death.
Volume: 274
Issue: 2
Pages: 1156-63
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Publication
19454696 | J:148860
First Author: Zhang H
Year: 2009
Journal: J Immunol
Title: Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to Necroptosis.
Volume: 182
Issue: 11
Pages: 6993-7000
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Publication
21367852 | J:171123
First Author: Kodama T
Year: 2011
Journal: J Biol Chem
Title: BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
Volume: 286
Issue: 16
Pages: 13905-13
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Publication
9721221 | J:49766
First Author: Footz TK
Year: 1998
Journal: Genomics
Title: The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6.
Volume: 51
Issue: 3
Pages: 472-5
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Publication
23986435 | J:203931
First Author: Kodama T
Year: 2013
Journal: J Biol Chem
Title: The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
Volume: 288
Issue: 42
Pages: 30009-18
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Publication
19060338 | J:147600
First Author: Ni HM
Year: 2009
Journal: J Biol Chem
Title: Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice.
Volume: 284
Issue: 7
Pages: 4373-82
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Publication
27889208 | -
First Author: Stanger FV
Year: 2017
Journal: Structure
Title: The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook.
Volume: 25
Issue: 1
Pages: 203-211
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Publication
20028660 | J:158994
First Author: Bradfute SB
Year: 2010
Journal: J Immunol
Title: Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis.
Volume: 184
Issue: 1
Pages: 327-35
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Author
Bid H
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Author
Bid HK
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Publication
21533085 | J:172395
First Author: Schlatter R
Year: 2011
Journal: PLoS One
Title: Modeling the TNFα-induced apoptosis pathway in hepatocytes.
Volume: 6
Issue: 4
Pages: e18646
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Publication
25056906 | J:214844
First Author: Andree M
Year: 2014
Journal: EMBO J
Title: BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.
Volume: 33
Issue: 19
Pages: 2171-87
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Publication
19959756 | J:164154
First Author: McKenzie MD
Year: 2010
Journal: Diabetes
Title: Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
Volume: 59
Issue: 3
Pages: 644-52
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Publication
20392206 | J:163431
First Author: Azakir BA
Year: 2010
Journal: FEBS J
Title: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid.
Volume: 277
Issue: 5
Pages: 1319-30
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Publication
21478427 | J:174714
First Author: Geering B
Year: 2011
Journal: Blood
Title: A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils.
Volume: 117
Issue: 22
Pages: 5953-62
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Publication
27064265 | J:246489
First Author: Margaroli C
Year: 2016
Journal: Eur J Immunol
Title: Role of proapoptotic BH3-only proteins in Listeria monocytogenes infection.
Volume: 46
Issue: 6
Pages: 1427-37
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Publication
10476969 | J:57073
First Author: Yin XM
Year: 1999
Journal: Nature
Title: Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
Volume: 400
Issue: 6747
Pages: 886-91
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Publication
19109183 | J:142888
First Author: Ziporen L
Year: 2009
Journal: J Immunol
Title: Programmed necrotic cell death induced by complement involves a Bid-dependent pathway.
Volume: 182
Issue: 1
Pages: 515-21
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Publication
27196317 | J:253183
First Author: Yu C
Year: 2016
Journal: PLoS One
Title: Gene Expression Analysis Indicates Divergent Mechanisms in DEN-Induced Carcinogenesis in Wild Type and Bid-Deficient Livers.
Volume: 11
Issue: 5
Pages: e0155211
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Publication
17056520 | J:140532
First Author: Pradhan S
Year: 2006
Journal: J Immunol
Title: CD4 T cell-induced, bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responses.
Volume: 177
Issue: 9
Pages: 5956-67
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Publication
17641050 | J:149939
First Author: Wang HL
Year: 2007
Journal: J Immunol
Title: The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death.
Volume: 179
Issue: 3
Pages: 1834-41
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