Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramalingam A |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging. |
Volume: |
68 |
Issue: |
6 |
Pages: |
1683-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simionescu-Bankston A |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis. |
Volume: |
382 |
Issue: |
1 |
Pages: |
160-71 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797224 |
|
Stage: |
TS24 |
Assay Id: |
MGI:3777431 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
E16 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797224 |
|
Stage: |
TS24 |
Assay Id: |
MGI:3777431 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
E16 Tfm |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797226 |
|
Stage: |
TS26 |
Assay Id: |
MGI:3777431 |
Age: |
embryonic day 18.0 |
|
|
Specimen Label: |
E18 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797226 |
|
Stage: |
TS26 |
Assay Id: |
MGI:3777431 |
Age: |
embryonic day 18.0 |
|
|
Specimen Label: |
E18 Tfm |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
1 Tfm |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 5 |
|
|
Specimen Label: |
5 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 5 |
|
|
Specimen Label: |
5 Tfm |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 7 |
|
|
Specimen Label: |
7 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 7 |
|
|
Specimen Label: |
7 Tfm |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 10 |
|
|
Specimen Label: |
10 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 10 |
|
|
Specimen Label: |
10 Tfm |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 15 |
|
|
Specimen Label: |
15 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 15 |
|
|
Specimen Label: |
15 Tfm |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 20 |
|
|
Specimen Label: |
20 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 20 |
|
|
Specimen Label: |
20 Tfm |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 25 |
|
|
Specimen Label: |
25 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal day 25 |
|
|
Specimen Label: |
25 Tfm |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Adult |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3774022 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3777431 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Adult Tfm |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7447143 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-03-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783824 |
|
Stage: |
TS24 |
Assay Id: |
MGI:7447164 |
Age: |
embryonic day 16.5 |
Image: |
S11 |
|
Specimen Label: |
E16.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7447143 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-03-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783827 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7447164 |
Age: |
postnatal day 3 |
Image: |
S11 |
|
Specimen Label: |
P3 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3655614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-09-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3655655 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3655614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-09-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3655655 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3655614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-09-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638217 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3655655 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3655614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-09-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638817 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3655655 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marcucci MJ |
Year: |
2001 |
Journal: |
GenBank Submission |
Title: |
Mus musculus RVS161 mRNA, complete cds |
|
|
Pages: |
AF244361 |
|
•
•
•
•
•
|
Publication |
First Author: |
Routhier EL |
Year: |
2000 |
Journal: |
GenBank Submission |
Title: |
Mus musculus bridging integrator-3 mRNA, complete cds |
|
|
Pages: |
AF271733 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xue W |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. |
Volume: |
109 |
Issue: |
21 |
Pages: |
8212-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choquet H |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. |
Volume: |
12 |
Issue: |
1 |
Pages: |
3595 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Shaughnessy PJ |
Year: |
2007 |
Journal: |
Endocrinology |
Title: |
Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis. |
Volume: |
148 |
Issue: |
6 |
Pages: |
2914-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fowles LF |
Year: |
2003 |
Journal: |
Genesis |
Title: |
Genomic screen for genes involved in mammalian craniofacial development. |
Volume: |
35 |
Issue: |
2 |
Pages: |
73-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
bridging integrator 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Publication |
First Author: |
Singh N |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo. |
Volume: |
352 |
Issue: |
1 |
Pages: |
104-15 |
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Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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Publication |
First Author: |
Routhier EL |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p. |
Volume: |
276 |
Issue: |
24 |
Pages: |
21670-7 |
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Publication |
First Author: |
Zhu W |
Year: |
2000 |
Journal: |
Gene |
Title: |
Identification of drosophila bicoid-interacting proteins using a custom two-hybrid selection. |
Volume: |
245 |
Issue: |
2 |
Pages: |
329-39 |
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Protein Domain |
Type: |
Domain |
Description: |
Bin3 contains a tripartite S-adenosyl-L-methionine (SAM) bindingmotif with three sequence motifs, I/Ia, II, and III []. It is found in the following proteins:Drosophila melanogaster probable methyltransferase Bin3 (EC 2.1.1.-). It interacts with bicoid/bcd.Human 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) orBicoid-interacting protein 3 homologue (Bin3 homolog), a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap atthe 5'-end of 7SK snRNA, leading to stabilise it.Caenorhabditis elegans probable methyltransferase Y17G7B.18 (EC 2.1.1.-).This entry represents the Bin3-type SAM binding domain. |
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Protein Domain |
Type: |
Domain |
Description: |
BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions []. Bridging integrator 3 (Bin3) is widely expressed in many tissues except in the brain. It plays roles in regulating filamentous actin localization and in cell division. In humans, the Bin3 gene is located in chromosome 8p21.3, a region that is implicated in cancer suppression. Homozygous inactivation of the Bin3 gene in mice led to the development of cataracts and an increased likelihood of lymphomas during aging, suggesting a role for Bin3 in lens development and cancer suppression []. BAR domains form dimers that bind to membranes, induce membrane bending and curvature, and may also be involved in protein-protein interactions []. |
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Publication |
First Author: |
Zadik D |
Year: |
1976 |
Journal: |
Refuat Hapeh Vehashinayim |
Title: |
Caries and the planning of dental treatment for five-year-old children. |
Volume: |
25 |
Issue: |
4 |
Pages: |
17-21 |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the C-terminal conserved region of the Drosophila probable RNA methyltransferase bin3 []. Proteins containing this domain also include human pre-miRNA 5'-monophosphate methyltransferase BCDIN3D []and 7SK snRNA methylphosphate capping enzyme MEPCE []. This domain contains a conserved HLN motif. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
32
 |
Fragment?: |
true |
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