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Search results 1 to 100 out of 177 for Birc3

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
330 | BIRC3
Type: gene
Organism: human
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Gene
451507 | BIRC3
Type: gene
Organism: chimpanzee
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Gene
514386 | BIRC3
Type: gene
Organism: cattle
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Gene
702468 | BIRC3
Type: gene
Organism: macaque, rhesus
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Gene
78971 | Birc3
Type: gene
Organism: rat
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Gene
489433 | BIRC3
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1197007 | Birc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27074575 | J:316252
First Author: Gressot LV
Year: 2017
Journal: Oncotarget
Title: Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma.
Volume: 8
Issue: 8
Pages: 12695-12704
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Publication
19276372 | J:147073
First Author: Ma O
Year: 2009
Journal: Cancer Res
Title: MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.
Volume: 69
Issue: 6
Pages: 2559-67
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Publication
23250032 | J:194607
First Author: Tan BM
Year: 2013
Journal: Diabetologia
Title: Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells.
Volume: 56
Issue: 3
Pages: 520-32
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Publication
37789765 | J:342656
First Author: Schorn F
Year: 2023
Journal: EMBO J
Title: cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.
Volume: 42
Issue: 22
Pages: e113614
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Protein
Q921N0
Organism: Mus musculus/domesticus
Length: 376  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0031762 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1197007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034143 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033456 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014640 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032882 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16382159 | J:144012
First Author: Conte D
Year: 2006
Journal: Mol Cell Biol
Title: Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival.
Volume: 26
Issue: 2
Pages: 699-708
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Publication
35718775 | J:326045
First Author: Biswas DD
Year: 2022
Journal: J Neuroinflammation
Title: Cellular inhibitor of apoptosis 2 (cIAP2) restricts neuroinflammation during experimental autoimmune encephalomyelitis.
Volume: 19
Issue: 1
Pages: 158
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Publication
17321613 | J:121358
First Author: Chua CC
Year: 2007
Journal: Biochim Biophys Acta
Title: Overexpression of IAP-2 attenuates apoptosis and protects against myocardial ischemia/reperfusion injury in transgenic mice.
Volume: 1773
Issue: 4
Pages: 577-83
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509537
Age: embryonic day 10.5
Image: 1 - left embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1 - left embryo
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3509537
Age: embryonic day 10.5
Image: 2 - right embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 2 - right embryo
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506858
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539827
Age: embryonic day 15.5
Image: GUDMAP:6210
Specimen Label: GUDMAP:6210
Detected: true
Specimen Num: 1
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Publication
9441758 | J:45561
First Author: Liston P
Year: 1997
Journal: Genomics
Title: Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes.
Volume: 46
Issue: 3
Pages: 495-503
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Publication
29452637 | J:260804
First Author: Annibaldi A
Year: 2018
Journal: Mol Cell
Title: Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.
Volume: 69
Issue: 4
Pages: 566-580.e5
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Publication
31126323 | J:302874
First Author: Lala-Tabbert N
Year: 2019
Journal: Skelet Muscle
Title: Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy.
Volume: 9
Issue: 1
Pages: 13
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Publication
23799077 | J:199221
First Author: Giardino Torchia ML
Year: 2013
Journal: PLoS One
Title: c-IAP1 and c-IAP2 redundancy differs between T and B cells.
Volume: 8
Issue: 6
Pages: e66161
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Publication
26096449 | J:232951
First Author: Giardino Torchia ML
Year: 2015
Journal: Eur J Immunol
Title: c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival.
Volume: 45
Issue: 9
Pages: 2672-82
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Publication
23248260 | J:191721
First Author: Giardino Torchia ML
Year: 2013
Journal: J Immunol
Title: Balance between NF-κB p100 and p52 regulates T cell costimulation dependence.
Volume: 190
Issue: 2
Pages: 549-55
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Publication
18784070 | J:143118
First Author: Mace PD
Year: 2008
Journal: J Biol Chem
Title: Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.
Volume: 283
Issue: 46
Pages: 31633-40
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Publication
21331077 | J:203399
First Author: Darding M
Year: 2011
Journal: Cell Death Differ
Title: Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.
Volume: 18
Issue: 8
Pages: 1376-86
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Publication
26037070 | J:317525
First Author: Dagenais M
Year: 2016
Journal: Mucosal Immunol
Title: A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways.
Volume: 9
Issue: 1
Pages: 146-58
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Publication
24633224 | J:215110
First Author: Guicciardi ME
Year: 2014
Journal: PLoS One
Title: Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity.
Volume: 9
Issue: 3
Pages: e92124
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Publication
22332634 | J:184293
First Author: Kenneth NS
Year: 2012
Journal: Biochem J
Title: An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.
Volume: 443
Issue: 2
Pages: 355-9
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Publication
21048983 | J:166899
First Author: Conze DB
Year: 2010
Journal: PLoS Biol
Title: Non-canonical NF-κB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.
Volume: 8
Issue: 10
Pages: e1000518
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Publication
22195745 | J:179280
First Author: Labbé K
Year: 2011
Journal: Immunity
Title: Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome.
Volume: 35
Issue: 6
Pages: 897-907
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Publication
28647349 | J:252195
First Author: Anderton H
Year: 2017
Journal: J Invest Dermatol
Title: Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.
Volume: 137
Issue: 11
Pages: 2371-2379
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Publication
15798218 | J:97656
First Author: Conze DB
Year: 2005
Journal: Mol Cell Biol
Title: Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.
Volume: 25
Issue: 8
Pages: 3348-56
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Publication
18684108 | J:140404
First Author: Rumble JM
Year: 2008
Journal: Biochem J
Title: Apoptotic sensitivity of murine IAP-deficient cells.
Volume: 415
Issue: 1
Pages: 21-5
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Publication
19464198 | J:149992
First Author: Bertrand MJ
Year: 2009
Journal: Immunity
Title: Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
Volume: 30
Issue: 6
Pages: 789-801
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Publication
23074266 | J:258575
First Author: Enwere EK
Year: 2012
Journal: Sci Signal
Title: TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway.
Volume: 5
Issue: 246
Pages: ra75
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Publication
23184147 | J:192578
First Author: Enwere EK
Year: 2013
Journal: Hum Mol Genet
Title: Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice.
Volume: 22
Issue: 5
Pages: 867-78
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Publication
28055006 | J:329370
First Author: Guicciardi ME
Year: 2017
Journal: Cell Death Dis
Title: Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice.
Volume: 8
Issue: 1
Pages: e2535
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Publication
12153481 | J:78107
First Author: Ishigaki S
Year: 2002
Journal: J Neurochem
Title: X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration.
Volume: 82
Issue: 3
Pages: 576-84
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Publication
12679106 | J:82848
First Author: Kawamura K
Year: 2003
Journal: Dev Biol
Title: Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos.
Volume: 256
Issue: 2
Pages: 331-41
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Publication
15608679 | J:96095
First Author: Lang G
Year: 2005
Journal: Oncogene
Title: Myb proteins regulate the expression of diverse target genes.
Volume: 24
Issue: 8
Pages: 1375-84
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Publication
23109427 | J:192843
First Author: Tigno-Aranjuez JT
Year: 2013
Journal: Mol Cell Biol
Title: A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
Volume: 33
Issue: 1
Pages: 146-58
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Publication
23126497 | J:214051
First Author: Yamaguchi N
Year: 2012
Journal: Genes Cells
Title: cIAP1/2 negatively regulate RANKL-induced osteoclastogenesis through the inhibition of NFATc1 expression.
Volume: 17
Issue: 12
Pages: 971-81
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Publication
29191979 | J:256176
First Author: Suzuki S
Year: 2018
Journal: EMBO Rep
Title: Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation.
Volume: 19
Issue: 1
Pages: 89-101
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Publication
8548810 | J:30406
First Author: Rothe M
Year: 1995
Journal: Cell
Title: The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.
Volume: 83
Issue: 7
Pages: 1243-52
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Publication
23334419 | J:194553
First Author: Hu H
Year: 2013
Journal: Nature
Title: OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3.
Volume: 494
Issue: 7437
Pages: 371-4
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Publication
19815541 | J:158223
First Author: Vince JE
Year: 2009
Journal: J Biol Chem
Title: TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
Volume: 284
Issue: 51
Pages: 35906-15
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Publication
24439895 | J:315317
First Author: Rodrigue-Gervais IG
Year: 2014
Journal: Cell Host Microbe
Title: Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival.
Volume: 15
Issue: 1
Pages: 23-35
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Publication
21300983 | J:172843
First Author: Gardam S
Year: 2011
Journal: Blood
Title: Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response.
Volume: 117
Issue: 15
Pages: 4041-51
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Publication
25902529 | J:221325
First Author: Ebert G
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.
Volume: 112
Issue: 18
Pages: 5797-802
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Publication
32234472 | J:287642
First Author: Ebert G
Year: 2020
Journal: Cell Rep
Title: Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection.
Volume: 30
Issue: 13
Pages: 4343-4354.e4
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Publication
22576661 | J:204788
First Author: McComb S
Year: 2012
Journal: Cell Death Differ
Title: cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation.
Volume: 19
Issue: 11
Pages: 1791-801
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Publication
20676140 | J:165292
First Author: Cheng L
Year: 2010
Journal: Oncogene
Title: Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency.
Volume: 29
Issue: 42
Pages: 5700-11
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Publication
33608556 | J:303642
First Author: Gao P
Year: 2021
Journal: Nat Commun
Title: E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
Volume: 12
Issue: 1
Pages: 1194
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Publication
14623868 | J:86711
First Author: Potts PR
Year: 2003
Journal: J Cell Biol
Title: Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.
Volume: 163
Issue: 4
Pages: 789-99
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Publication
14634619 | J:86910
First Author: Liston P
Year: 2003
Journal: Oncogene
Title: The inhibitors of apoptosis: there is more to life than Bcl2.
Volume: 22
Issue: 53
Pages: 8568-80
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Publication
23815148 | J:216562
First Author: Etemadi N
Year: 2013
Journal: FEBS J
Title: Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.
Volume: 280
Issue: 21
Pages: 5283-97
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Publication
18621737 | J:141856
First Author: Varfolomeev E
Year: 2008
Journal: J Biol Chem
Title: c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
Volume: 283
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Year: 2019
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Title: Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
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Journal: EMBO J
Title: IAPs limit activation of RIP kinases by TNF receptor 1 during development.
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Title: cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner.
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Title: Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression.
Volume: 377
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Journal: Genes Dev
Title: Regulation of apoptosis by XIAP ubiquitin-ligase activity.
Volume: 22
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Journal: Oncogene
Title: The inhibitors of apoptosis (IAPs) and their emerging role in cancer.
Volume: 17
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Year: 2010
Journal: Nat Immunol
Title: Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines.
Volume: 11
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Year: 2019
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Title: Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development.
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Issue: 11
Pages: 790
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First Author: Vanlangenakker N
Year: 2011
Journal: Cell Death Differ
Title: cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.
Volume: 18
Issue: 4
Pages: 656-65
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Year: 2011
Journal: Nat Immunol
Title: The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.
Volume: 12
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Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
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First Author: Vince JE
Year: 2012
Journal: Immunity
Title: Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Volume: 36
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Pages: 215-27
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