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Search results 1 to 100 out of 913 for Bpi

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
671 | BPI
Type: gene
Organism: human
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Gene
548411 | bpi
Type: gene
Organism: frog, western clawed
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Gene
296321 | Bpi
Type: gene
Organism: rat
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Gene
477226 | BPI
Type: gene
Organism: dog, domestic
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Gene
458238 | BPI
Type: gene
Organism: chimpanzee
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Gene
280734 | BPI
Type: gene
Organism: cattle
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Gene
574153 | BPI
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR030181 | BPI
Type: Family
Description: Bactericidal/permeability-increasing protein (BPI) is a potent antimicrobial protein that binds to and neutralises lipopolysaccharide (LPS), a glycolipid present in the outer membrane of Gram-negative bacteria [].In mammals, two related LPS-binding proteins mediate the biological effects of LPS: LPS-binding protein (LBP) and BPI. LBP is a plasma protein that enhances the inflammatory response to LPS, whereas BPI is found in lysosomal granules of polymorphonuclear neutrophils, is bactericidal, and neutralises the toxic effects of LPS []. BPI belongs to the lipid transfer/lipopolysaccharide binding protein (LT/LBP) family, with LBP, the cholesteryl ester transfer protein (CETP) and the phospholipid transfer protein (PLTP) [].This entry represents mammalian BPI.
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Protein Coding Gene
MGI:3045315 | Bpi
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q67E05
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Publication
7613727 | -
First Author: Elsbach P
Year: 1995
Journal: Infect Agents Dis
Title: Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections.
Volume: 4
Issue: 2
Pages: 102-9
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Publication
34815797 | J:314951
First Author: Chuang HC
Year: 2021
Journal: Theranostics
Title: BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus.
Volume: 11
Issue: 20
Pages: 9953-9966
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Publication
21787333 | J:174122
First Author: Bingle CD
Year: 2011
Journal: Biochem Soc Trans
Title: Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Volume: 39
Issue: 4
Pages: 977-83
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Publication
11083872 | J:67597
First Author: Desrumaux C
Year: 2001
Journal: J Biol Chem
Title: A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins.
Volume: 276
Issue: 8
Pages: 5908-15
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Publication
7517398 | -
First Author: Wilde CG
Year: 1994
Journal: J Biol Chem
Title: Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation.
Volume: 269
Issue: 26
Pages: 17411-6
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Publication
21787330 | J:174123
First Author: Bingle CD
Year: 2011
Journal: Biochem Soc Trans
Title: Distant cousins: genomic and sequence diversity within the BPI fold-containing (BPIF)/PLUNC protein family.
Volume: 39
Issue: 4
Pages: 961-5
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Publication
23499554 | J:195535
First Author: Liu Y
Year: 2013
Journal: Am J Pathol
Title: SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection.
Volume: 182
Issue: 5
Pages: 1519-31
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Publication
18490755 | J:136329
First Author: Wittmann I
Year: 2008
Journal: J Immunol
Title: Murine bactericidal/permeability-increasing protein inhibits the endotoxic activity of lipopolysaccharide and gram-negative bacteria.
Volume: 180
Issue: 11
Pages: 7546-52
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Publication
16365446 | J:126268
First Author: Eckert M
Year: 2006
Journal: J Immunol
Title: Endotoxin-induced expression of murine bactericidal permeability/increasing protein is mediated exclusively by toll/IL-1 receptor domain-containing adaptor inducing IFN-beta-dependent pathways.
Volume: 176
Issue: 1
Pages: 522-8
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Publication
15590754 | J:96429
First Author: Lennartsson A
Year: 2005
Journal: J Leukoc Biol
Title: A murine antibacterial ortholog to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.
Volume: 77
Issue: 3
Pages: 369-77
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Publication
34272233 | J:359104
First Author: Theprungsirikul J
Year: 2021
Journal: J Immunol
Title: Differential Enhancement of Neutrophil Phagocytosis by Anti-Bactericidal/Permeability-Increasing Protein Antibodies.
Volume: 207
Issue: 3
Pages: 777-783
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Publication
33552078 | J:345173
 
First Author: Kong Q
Year: 2020
Journal: Front Immunol
Title: Bactericidal Permeability Increasing Protein Deficiency Aggravates Acute Colitis in Mice by Increasing the Serum Levels of Lipopolysaccharide.
Volume: 11
Pages: 614169
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Publication
33981306 | J:308251
 
First Author: Theprungsirikul J
Year: 2021
Journal: Front Immunol
Title: Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas aeruginosa In Vivo via CD18-Dependent Phagocytosis.
Volume: 12
Pages: 659523
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Publication
38457343 | J:346703
First Author: Bülow S
Year: 2024
Journal: Cell Rep
Title: Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response.
Volume: 43
Issue: 3
Pages: 113929
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Gene
254240 | BPIFC
Type: gene
Organism: human
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Protein Coding Gene
MGP_CAROLIEiJ_G0024585 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3045315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026611 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026029 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025507 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
14745963 | J:88670
First Author: Hou J
Year: 2004
Journal: Dev Dyn
Title: Identification of a novel left-right asymmetrically expressed gene in the mouse belonging to the BPI/PLUNC superfamily.
Volume: 229
Issue: 2
Pages: 373-9
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Gene
51297 | BPIFA1
Type: gene
Organism: human
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Gene
92747 | BPIFB1
Type: gene
Organism: human
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Gene
80341 | BPIFB2
Type: gene
Organism: human
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Gene
128859 | BPIFB6
Type: gene
Organism: human
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Gene
140683 | BPIFA2
Type: gene
Organism: human
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Gene
128861 | BPIFA3
Type: gene
Organism: human
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Gene
359710 | BPIFB3
Type: gene
Organism: human
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Gene
149954 | BPIFB4
Type: gene
Organism: human
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Gene
317716 | BPIFA4P
Type: gene
Organism: human
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Gene
402016 | BPIFB9P
Type: gene
Organism: human
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Gene
100505383 | BPIFB5P
Type: gene
Organism: human
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
28775000 | J:256173
First Author: Kota SK
Year: 2017
Journal: J Am Soc Nephrol
Title: BPI Fold-Containing Family A Member 2/Parotid Secretory Protein Is an Early Biomarker of AKI.
Volume: 28
Issue: 12
Pages: 3473-3478
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Publication
15028288 | J:89262
First Author: LeClair EE
Year: 2004
Journal: Genomics
Title: Cloning and expression of a mouse member of the PLUNC protein family exclusively expressed in tongue epithelium.
Volume: 83
Issue: 4
Pages: 658-66
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Protein
D3YTT0
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
Q9D9J8
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Protein
Q61114
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
A6PWW6
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: true
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Protein
Q80X83
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
H3BLP6
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
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Protein
P97361
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
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Protein
Q8BU51
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q80ZU7
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
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Protein
Q8C186
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
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Publication
10224143 | J:54521
First Author: Weston WM
Year: 1999
Journal: J Biol Chem
Title: Differential display identification of plunc, a novel gene expressed in embryonic palate, nasal epithelium, and adult lung.
Volume: 274
Issue: 19
Pages: 13698-703
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Publication
11396972 | J:70027
First Author: LeClair EE
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genomic organization of the mouse plunc gene and expression in the developing airways and thymus.
Volume: 284
Issue: 3
Pages: 792-7
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Publication
2582349 | J:34577
First Author: Madsen HO
Year: 1985
Journal: Nucleic Acids Res
Title: Molecular cloning of mouse PSP mRNA.
Volume: 13
Issue: 1
Pages: 1-13
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Protein
Q9CQX3
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: false
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Protein Domain
IPR032950 | BPIFC
Type: Family
Description: BPI fold-containing family C protein, also known as bactericidal/permeability-increasing protein-like 2 (BPIL2), is a lipid transfer/lipopolysaccharide binding protein that seems to share an evolutionary origin with BPIL1 and BPIL3. BPIL2 shows prominent expression in psoriasis patients skin [].
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Protein Coding Gene
MGI:3026884 | Bpifc
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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