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Search results 1 to 100 out of 736 for Braf

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression
Probe: MGI:2673435
Assay Type: RNA in situ
Annotation Date: 2003-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:2673449
Age: embryonic day 15.5
Image: Braf
Note: Authors state that there is ubiquitous expression.
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Diedrich B
Year: 2017
Journal: EMBO J
Title: Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.
Volume: 36
Issue: 5
Pages: 646-663
Publication
First Author: Koh HY
Year: 2018
Journal: Nat Med
Title: BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.
Volume: 24
Issue: 11
Pages: 1662-1668
Publication
First Author: Kamata T
Year: 2010
Journal: Cancer Res
Title: BRAF inactivation drives aneuploidy by deregulating CRAF.
Volume: 70
Issue: 21
Pages: 8475-86
Publication
First Author: Perna D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.
Volume: 112
Issue: 6
Pages: E536-45
Publication
First Author: Nieto P
Year: 2017
Journal: Nature
Title: A Braf kinase-inactive mutant induces lung adenocarcinoma.
Volume: 548
Issue: 7666
Pages: 239-243
Publication
First Author: Dhomen N
Year: 2009
Journal: Cancer Cell
Title: Oncogenic Braf induces melanocyte senescence and melanoma in mice.
Volume: 15
Issue: 4
Pages: 294-303
Publication
First Author: McNeill RS
Year: 2016
Journal: Am J Pathol
Title: BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea-Induced Gliomagenesis.
Volume: 186
Issue: 10
Pages: 2551-4
Publication
First Author: Brady DC
Year: 2014
Journal: Nature
Title: Copper is required for oncogenic BRAF signalling and tumorigenesis.
Volume: 509
Issue: 7501
Pages: 492-6
Publication
First Author: Zhao ZQ
Year: 2013
Journal: J Clin Invest
Title: Chronic itch development in sensory neurons requires BRAF signaling pathways.
Volume: 123
Issue: 11
Pages: 4769-80
Publication
First Author: Nelson DS
Year: 2019
Journal: PLoS One
Title: BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.
Volume: 14
Issue: 9
Pages: e0222400
Publication
First Author: Tien AC
Year: 2012
Journal: Development
Title: Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.
Volume: 139
Issue: 14
Pages: 2477-87
Publication
First Author: Wojnowski L
Year: 2000
Journal: Mech Dev
Title: Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis.
Volume: 91
Issue: 1-2
Pages: 97-104
Publication
First Author: Gronych J
Year: 2011
Journal: J Clin Invest
Title: An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.
Volume: 121
Issue: 4
Pages: 1344-8
Publication
First Author: Sievert AJ
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.
Volume: 110
Issue: 15
Pages: 5957-62
Publication
First Author: Ruiz R
Year: 2017
Journal: PLoS Genet
Title: The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.
Volume: 13
Issue: 7
Pages: e1006913
Publication
First Author: Charles RP
Year: 2014
Journal: Mol Cancer Res
Title: Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis.
Volume: 12
Issue: 7
Pages: 979-86
Publication
First Author: Kamata T
Year: 2013
Journal: Mol Cancer Res
Title: Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720.
Volume: 11
Issue: 12
Pages: 1530-41
Publication
First Author: Köhler C
Year: 2017
Journal: Cell Stem Cell
Title: Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.
Volume: 21
Issue: 5
Pages: 679-693.e6
Publication
First Author: Sanchez-Laorden B
Year: 2014
Journal: Sci Signal
Title: BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.
Volume: 7
Issue: 318
Pages: ra30
Publication
First Author: de Keizer PL
Year: 2010
Journal: Cancer Res
Title: Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.
Volume: 70
Issue: 21
Pages: 8526-36
Publication
First Author: Dhomen N
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Inducible expression of (V600E) Braf using tyrosinase-driven Cre recombinase results in embryonic lethality.
Volume: 23
Issue: 1
Pages: 112-20
Publication
First Author: Heidorn SJ
Year: 2010
Journal: Cell
Title: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
Volume: 140
Issue: 2
Pages: 209-21
Publication
First Author: Ho PC
Year: 2014
Journal: Cancer Res
Title: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Volume: 74
Issue: 12
Pages: 3205-17
Publication
First Author: Knight DA
Year: 2013
Journal: J Clin Invest
Title: Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Volume: 123
Issue: 3
Pages: 1371-81
Publication
First Author: Inoue SI
Year: 2017
Journal: Hum Mol Genet
Title: Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Volume: 26
Issue: 23
Pages: 4715-4727
Publication    
First Author: Shin J
Year: 2016
Journal: Elife
Title: BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.
Volume: 5
Publication
First Author: Pritchard C
Year: 2007
Journal: Biochem Soc Trans
Title: Mouse models for BRAF-induced cancers.
Volume: 35
Issue: Pt 5
Pages: 1329-33
Publication
First Author: Vandal G
Year: 2014
Journal: PLoS One
Title: Ras effector mutant expression suggest a negative regulator inhibits lung tumor formation.
Volume: 9
Issue: 1
Pages: e84745
Publication
First Author: Moriya M
Year: 2015
Journal: Hum Mol Genet
Title: Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.
Volume: 24
Issue: 25
Pages: 7349-60
Publication
First Author: Steinberg SM
Year: 2017
Journal: Cancer Res
Title: Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors.
Volume: 77
Issue: 7
Pages: 1599-1610
Publication
First Author: Pfeiffer V
Year: 2013
Journal: PLoS One
Title: Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum.
Volume: 8
Issue: 3
Pages: e58259
Publication
First Author: Wu X
Year: 2012
Journal: Mol Cell Biol
Title: Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants.
Volume: 32
Issue: 19
Pages: 3872-90
Publication  
First Author: Janardhan HP
Year: 2020
Journal: J Exp Med
Title: KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition.
Volume: 217
Issue: 7
Publication    
First Author: Ruiz-Vega R
Year: 2020
Journal: Elife
Title: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes.
Volume: 9
Publication
First Author: Parhar RS
Year: 2016
Journal: Lab Invest
Title: IL-12 immunotherapy of Braf(V600E)-induced papillary thyroid cancer in a mouse model.
Volume: 96
Issue: 1
Pages: 89-97
Publication
First Author: Braun AD
Year: 2020
Journal: J Invest Dermatol
Title: Activated Hgf-Met Signaling Cooperates with Oncogenic BRAF to Drive Primary Cutaneous Melanomas and Angiotropic Lung Metastases in Mice.
Volume: 140
Issue: 7
Pages: 1410-1417.e2
Publication
First Author: Inoue SI
Year: 2019
Journal: Hum Mol Genet
Title: C-type natriuretic peptide improves growth retardation in a mouse model of cardio-facio-cutaneous syndrome.
Volume: 28
Issue: 1
Pages: 74-83
Publication
First Author: Shen CH
Year: 2013
Journal: Mol Cell
Title: Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation.
Volume: 52
Issue: 2
Pages: 161-72
Publication
First Author: Inoue S
Year: 2014
Journal: Hum Mol Genet
Title: New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.
Volume: 23
Issue: 24
Pages: 6553-66
Publication
First Author: Nagarajah J
Year: 2016
Journal: J Clin Invest
Title: Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine.
Volume: 126
Issue: 11
Pages: 4119-4124
Publication
First Author: Montero-Conde C
Year: 2013
Journal: Cancer Discov
Title: Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
Volume: 3
Issue: 5
Pages: 520-33
Publication
First Author: Wefers B
Year: 2012
Journal: PLoS One
Title: MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.
Volume: 7
Issue: 4
Pages: e35035
Publication
First Author: Hogstad B
Year: 2018
Journal: J Exp Med
Title: RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions.
Volume: 215
Issue: 1
Pages: 319-336
Publication
First Author: Galvani E
Year: 2020
Journal: Nat Commun
Title: Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Volume: 11
Issue: 1
Pages: 853
Publication
First Author: Kamata T
Year: 2005
Journal: Blood
Title: A critical function for B-Raf at multiple stages of myelopoiesis.
Volume: 106
Issue: 3
Pages: 833-40
Publication
First Author: Köhler M
Year: 2019
Journal: Oncogene
Title: B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model.
Volume: 38
Issue: 8
Pages: 1324-1339
Publication
First Author: Sobczak I
Year: 2008
Journal: Oncogene
Title: B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.
Volume: 27
Issue: 35
Pages: 4779-87
Publication
First Author: Rae J
Year: 2012
Journal: J Invest Dermatol
Title: (V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
Volume: 132
Issue: 2
Pages: 488-91
Publication
First Author: Chen S
Year: 2019
Journal: Nat Commun
Title: Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.
Volume: 10
Issue: 1
Pages: 877
Publication
First Author: Viros A
Year: 2014
Journal: Nature
Title: Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53.
Volume: 511
Issue: 7510
Pages: 478-482
Publication
First Author: Mass E
Year: 2017
Journal: Nature
Title: A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.
Volume: 549
Issue: 7672
Pages: 389-393
Publication
First Author: Mercer K
Year: 2005
Journal: Cancer Res
Title: Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts.
Volume: 65
Issue: 24
Pages: 11493-500
Publication
First Author: Maertens O
Year: 2013
Journal: Cancer Discov
Title: Elucidating distinct roles for NF1 in melanomagenesis.
Volume: 3
Issue: 3
Pages: 338-49
Publication
First Author: Tanaka H
Year: 2019
Journal: Cancer Sci
Title: Overproduction of thrombopoietin by BRAFV600E-mutated mouse hepatocytes and contribution of thrombopoietin to hepatocarcinogenesis.
Volume: 110
Issue: 9
Pages: 2748-2759
Publication
First Author: Dorard C
Year: 2019
Journal: FEBS J
Title: RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell-cell junctions.
Volume: 286
Issue: 12
Pages: 2277-2294
Publication
First Author: Chen AP
Year: 2006
Journal: J Neurosci Res
Title: Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory.
Volume: 83
Issue: 1
Pages: 28-38
Publication
First Author: Tabor V
Year: 2014
Journal: Cancer Res
Title: MYC synergizes with activated BRAFV600E in mouse lung tumor development by suppressing senescence.
Volume: 74
Issue: 16
Pages: 4222-9
Publication    
First Author: Sakamoto N
Year: 2017
Journal: Elife
Title: BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.
Volume: 6
Publication
First Author: González-Sánchez E
Year: 2013
Journal: PLoS One
Title: Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomas.
Volume: 8
Issue: 6
Pages: e66933
Publication
First Author: Kim SH
Year: 2017
Journal: J Invest Dermatol
Title: Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma.
Volume: 137
Issue: 8
Pages: 1740-1748
Publication
First Author: Jolly LA
Year: 2016
Journal: Cancer Res
Title: Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss.
Volume: 76
Issue: 7
Pages: 1804-13
Publication
First Author: Strohecker AM
Year: 2013
Journal: Cancer Discov
Title: Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors.
Volume: 3
Issue: 11
Pages: 1272-85
Publication
First Author: Dillon TJ
Year: 2013
Journal: Int Immunol
Title: B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells.
Volume: 25
Issue: 4
Pages: 259-69
Publication
First Author: Valluet A
Year: 2010
Journal: PLoS One
Title: B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse.
Volume: 5
Issue: 12
Pages: e15272
Publication
First Author: Ishak Gabra MB
Year: 2020
Journal: Nat Commun
Title: Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Volume: 11
Issue: 1
Pages: 3326
Publication
First Author: Berres ML
Year: 2014
Journal: J Exp Med
Title: BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
Volume: 211
Issue: 4
Pages: 669-83
Publication
First Author: Yuan P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Volume: 110
Issue: 45
Pages: 18226-31
Publication
First Author: Blackshear PJ
Year: 1992
Journal: Genomics
Title: Chromosomal mapping of the human (MACS) and mouse (Macs) genes encoding the MARCKS protein.
Volume: 14
Issue: 1
Pages: 168-74
Publication
First Author: Peng W
Year: 2016
Journal: Cancer Discov
Title: Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Volume: 6
Issue: 2
Pages: 202-16
Publication
First Author: Mann MB
Year: 2015
Journal: Nat Genet
Title: Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.
Volume: 47
Issue: 5
Pages: 486-95
Publication
First Author: van Tuyn J
Year: 2017
Journal: J Invest Dermatol
Title: Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.
Volume: 137
Issue: 10
Pages: 2197-2207
DO Term
Publication    
First Author: Raguz J
Year: 2016
Journal: Elife
Title: Epidermal RAF prevents allergic skin disease.
Volume: 5
Publication
First Author: Rai TS
Year: 2014
Journal: Genes Dev
Title: HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Volume: 28
Issue: 24
Pages: 2712-25
Publication
First Author: Brighton HE
Year: 2018
Journal: Cancer Res
Title: New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Volume: 78
Issue: 2
Pages: 542-557
Publication
First Author: Shimamura M
Year: 2018
Journal: PLoS One
Title: Mouse models of sporadic thyroid cancer derived from BRAFV600E alone or in combination with PTEN haploinsufficiency under physiologic TSH levels.
Volume: 13
Issue: 8
Pages: e0201365
Publication
First Author: Knauf JA
Year: 2005
Journal: Cancer Res
Title: Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.
Volume: 65
Issue: 10
Pages: 4238-45
Publication
First Author: Wojnowski L
Year: 1997
Journal: Nat Genet
Title: Endothelial apoptosis in Braf-deficient mice.
Volume: 16
Issue: 3
Pages: 293-7
Publication
First Author: Pritchard CA
Year: 2004
Journal: Mol Cell Biol
Title: B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts.
Volume: 24
Issue: 13
Pages: 5937-52
Publication
First Author: Couto JP
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: STAT3 negatively regulates thyroid tumorigenesis.
Volume: 109
Issue: 35
Pages: E2361-70
Publication
First Author: Vial J
Year: 2019
Journal: Cell Death Differ
Title: The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death.
Volume: 26
Issue: 3
Pages: 443-454
Publication
First Author: Le Gal K
Year: 2015
Journal: Sci Transl Med
Title: Antioxidants can increase melanoma metastasis in mice.
Volume: 7
Issue: 308
Pages: 308re8
Publication
First Author: Luo X
Year: 2014
Journal: Cell Rep
Title: Isolation and molecular characterization of circulating melanoma cells.
Volume: 7
Issue: 3
Pages: 645-53
Publication
First Author: Muinonen-Martin AJ
Year: 2014
Journal: PLoS Biol
Title: Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.
Volume: 12
Issue: 10
Pages: e1001966
Publication
First Author: Long JE
Year: 2019
Journal: Cell Death Differ
Title: Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.
Volume: 26
Issue: 11
Pages: 2416-2429
Publication
First Author: Chen S
Year: 2017
Journal: Nature
Title: Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Volume: 549
Issue: 7672
Pages: 399-403
Publication
First Author: Hölzel M
Year: 2016
Journal: Cancer Res
Title: A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells.
Volume: 76
Issue: 2
Pages: 251-63
Publication
First Author: Kamata T
Year: 2017
Journal: Blood
Title: KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment.
Volume: 130
Issue: 4
Pages: 514-526
Publication
First Author: Spitzer MH
Year: 2017
Journal: Cell
Title: Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Volume: 168
Issue: 3
Pages: 487-502.e15
Publication  
First Author: Rodríguez CI
Year: 2018
Journal: Cancer Lett
Title: Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progression.
Volume: 414
Pages: 268-277
Publication
First Author: Rodríguez CI
Year: 2017
Journal: Mol Cancer Res
Title: EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Volume: 15
Issue: 12
Pages: 1792-1802
Publication
First Author: Zhao F
Year: 2018
Journal: Cancer Immunol Res
Title: Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.
Volume: 6
Issue: 12
Pages: 1459-1471
Publication
First Author: Hooijkaas AI
Year: 2012
Journal: Am J Pathol
Title: Targeting BRAFV600E in an inducible murine model of melanoma.
Volume: 181
Issue: 3
Pages: 785-94
Publication
First Author: Hong SW
Year: 2012
Journal: J Biol Chem
Title: Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).
Volume: 287
Issue: 28
Pages: 24017-25