|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 207 for Bscl2

<< First    < Previous  |  Next >    Last >>
0.02s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen W
Year: 2013
Journal: PLoS One
Title: Altered lipid metabolism in residual white adipose tissues of Bscl2 deficient mice.
Volume: 8
Issue: 12
Pages: e82526
Publication    
First Author: Zhou H
Year: 2019
Journal: JCI Insight
Title: Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
Volume: 5
Publication
First Author: Mcilroy GD
Year: 2018
Journal: Sci Rep
Title: Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet.
Volume: 8
Issue: 1
Pages: 17863
Publication  
First Author: Roumane A
Year: 2021
Journal: J Clin Med
Title: Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy.
Volume: 10
Issue: 3
Publication  
First Author: Dollet L
Year: 2016
Journal: Sci Rep
Title: Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode.
Volume: 6
Pages: 35487
Publication
First Author: Prieur X
Year: 2013
Journal: Diabetologia
Title: Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice.
Volume: 56
Issue: 8
Pages: 1813-25
Publication
First Author: Zhou H
Year: 2015
Journal: J Lipid Res
Title: Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals.
Volume: 56
Issue: 10
Pages: 1912-25
Publication
First Author: El Zowalaty AE
Year: 2018
Journal: Biol Reprod
Title: Seipin deficiency leads to increased endoplasmic reticulum stress and apoptosis in mammary gland alveolar epithelial cells during lactation.
Volume: 98
Issue: 4
Pages: 570-578
Publication
First Author: Zowalaty AEE
Year: 2017
Journal: Biol Reprod
Title: Seipin deficiency leads to defective parturition in mice.
Volume: 97
Issue: 3
Pages: 378-386
Publication  
First Author: McGrath C
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Exercise Increases Bone in SEIPIN Deficient Lipodystrophy, Despite Low Marrow Adiposity.
Volume: 12
Pages: 782194
Publication
First Author: Xiong J
Year: 2020
Journal: Diabetologia
Title: Heterozygous deletion of Seipin in islet beta cells of male mice has an impact on insulin synthesis and secretion through reduced PPARγ expression.
Volume: 63
Issue: 2
Pages: 338-350
Publication
First Author: El Zowalaty AE
Year: 2015
Journal: Cell Death Dis
Title: Seipin deficiency increases chromocenter fragmentation and disrupts acrosome formation leading to male infertility.
Volume: 6
Issue: 7
Pages: e1817
Publication
First Author: Dollet L
Year: 2016
Journal: Diabetes
Title: FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency.
Volume: 65
Issue: 11
Pages: 3410-3417
Publication
First Author: Joubert M
Year: 2017
Journal: Diabetes
Title: The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model.
Volume: 66
Issue: 4
Pages: 1030-1040
Publication  
First Author: Mcilroy GD
Year: 2020
Journal: Dis Model Mech
Title: Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy.
Volume: 13
Issue: 1
Publication
First Author: Liu L
Year: 2014
Journal: Diabetes
Title: Adipose-specific knockout of SEIPIN/BSCL2 results in progressive lipodystrophy.
Volume: 63
Issue: 7
Pages: 2320-31
Publication  
First Author: Xu W
Year: 2019
Journal: Mol Cell Endocrinol
Title: Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Volume: 482
Pages: 1-10
Publication
First Author: Chen W
Year: 2012
Journal: Mol Cell Biol
Title: Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation.
Volume: 32
Issue: 6
Pages: 1099-111
Publication
First Author: Chen W
Year: 2014
Journal: Endocrinology
Title: Molecular mechanisms underlying fasting modulated liver insulin sensitivity and metabolism in male lipodystrophic Bscl2/Seipin-deficient mice.
Volume: 155
Issue: 11
Pages: 4215-25
Publication
First Author: Chen Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Seinpin knockout exacerbates cerebral ischemia/reperfusion damage in mice.
Volume: 474
Issue: 2
Pages: 377-383
Publication
First Author: Liu XJ
Year: 2018
Journal: FASEB J
Title: Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue-kidney crosstalk.
Volume: 32
Issue: 10
Pages: 5550-5562
Publication
First Author: Qian Y
Year: 2016
Journal: J Neuroinflammation
Title: Neuronal seipin knockout facilitates Aβ-induced neuroinflammation and neurotoxicity via reduction of PPARγ in hippocampus of mouse.
Volume: 13
Issue: 1
Pages: 145
Publication  
First Author: Wu X
Year: 2021
Journal: Front Cardiovasc Med
Title: Seipin Deficiency Accelerates Heart Failure Due to Calcium Handling Abnormalities and Endoplasmic Reticulum Stress in Mice.
Volume: 8
Pages: 644128
Publication
First Author: Wang H
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Adipose tissue transplantation ameliorates lipodystrophy-associated metabolic disorders in seipin-deficient mice.
Volume: 316
Issue: 1
Pages: E54-E62
Publication
First Author: Bai B
Year: 2019
Journal: JACC Basic Transl Sci
Title: Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction.
Volume: 4
Issue: 8
Pages: 924-937
Publication  
First Author: Bruder-Nascimento T
Year: 2021
Journal: Int J Mol Sci
Title: Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy.
Volume: 22
Issue: 19
Publication
First Author: Cui X
Year: 2011
Journal: Hum Mol Genet
Title: Seipin ablation in mice results in severe generalized lipodystrophy.
Volume: 20
Issue: 15
Pages: 3022-30
Publication
First Author: Gao M
Year: 2020
Journal: Hum Mol Genet
Title: GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Volume: 29
Issue: 3
Pages: 432-443
Publication  
First Author: Mcilroy GD
Year: 2018
Journal: Mol Metab
Title: Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease.
Volume: 10
Pages: 55-65
Publication
First Author: Jiang M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Lack of testicular seipin causes teratozoospermia syndrome in men.
Volume: 111
Issue: 19
Pages: 7054-9
Publication
First Author: Peng XG
Year: 2011
Journal: J Lipid Res
Title: Quantification of liver fat in mice: comparing dual-echo Dixon imaging, chemical shift imaging, and 1H-MR spectroscopy.
Volume: 52
Issue: 10
Pages: 1847-55
Publication
First Author: Pagac M
Year: 2016
Journal: Cell Rep
Title: SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase.
Volume: 17
Issue: 6
Pages: 1546-1559
Publication  
First Author: Liao J
Year: 2018
Journal: Gene
Title: Dyslipidemia, steatohepatitis and atherogenesis in lipodystrophic apoE deficient mice with Seipin deletion.
Volume: 648
Pages: 82-88
Publication  
First Author: Chang H
Year: 2019
Journal: Neurobiol Dis
Title: Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance.
Volume: 127
Pages: 350-361
Publication
First Author: Wang M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Dysfunction of lipid metabolism in lipodystrophic Seipin-deficient mice.
Volume: 461
Issue: 2
Pages: 206-10
Publication
First Author: Wang M
Year: 2016
Journal: Biochim Biophys Acta
Title: Adipose tissue deficiency results in severe hyperlipidemia and atherosclerosis in the low-density lipoprotein receptor knockout mice.
Volume: 1861
Issue: 5
Pages: 410-8
Publication
First Author: Combot Y
Year: 2022
Journal: Cell Rep
Title: Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes.
Volume: 38
Issue: 2
Pages: 110213
Publication
First Author: Romere C
Year: 2016
Journal: Cell
Title: Asprosin, a Fasting-Induced Glucogenic Protein Hormone.
Volume: 165
Issue: 3
Pages: 566-79
Publication
First Author: Zhou L
Year: 2014
Journal: Hum Mol Genet
Title: Lack of seipin in neurons results in anxiety- and depression-like behaviors via down regulation of PPARγ.
Volume: 23
Issue: 15
Pages: 4094-102
Publication
First Author: Ito D
Year: 2008
Journal: Neurobiol Dis
Title: Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17.
Volume: 31
Issue: 2
Pages: 266-77
Publication
First Author: Kaisaki PJ
Year: 2002
Journal: Cytogenet Genome Res
Title: Localization, cDNA sequence and genomic organization of the rat seipin gene (Bscl2) and sequence analysis in inbred rat models of Type 2 diabetes mellitus.
Volume: 98
Issue: 1
Pages: 71-4
Publication
First Author: Li G
Year: 2015
Journal: Dis Model Mech
Title: Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ.
Volume: 8
Issue: 12
Pages: 1615-24
Publication
First Author: Yang W
Year: 2013
Journal: Biochem J
Title: Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus.
Volume: 452
Issue: 1
Pages: 37-44
Publication  
First Author: Zhou H
Year: 2020
Journal: Mol Metab
Title: Berardinelli-Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing.
Volume: 36
Pages: 100971
Publication
First Author: Bruder-Nascimento T
Year: 2019
Journal: Hypertension
Title: Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1-Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy.
Volume: 74
Issue: 6
Pages: 1399-1408
Publication
First Author: Peng XG
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Comparison of brown and white adipose tissue fat fractions in ob, seipin, and Fsp27 gene knockout mice by chemical shift-selective imaging and (1)H-MR spectroscopy.
Volume: 304
Issue: 2
Pages: E160-7
Publication
First Author: Zhou L
Year: 2016
Journal: J Neurosci
Title: Activation of PPARγ Ameliorates Spatial Cognitive Deficits through Restoring Expression of AMPA Receptors in Seipin Knock-Out Mice.
Volume: 36
Issue: 4
Pages: 1242-53
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Wei S
Year: 2013
Journal: J Neurochem
Title: Seipin regulates excitatory synaptic transmission in cortical neurons.
Volume: 124
Issue: 4
Pages: 478-89
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3691035
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3691035
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3691035
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3691035
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3691035
Age: embryonic day 3.5
Specimen Label: B
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3691035
Age: embryonic day 3.5
Specimen Label: B
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3691035
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3691035
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3691035
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3690944
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3691035
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:7447274
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:7447274
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447274
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447274
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920928
Stage: TS28
Assay Id: MGI:7447274
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3690228
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: BAT Ctrl
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3690228
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: BAT Myf5-BKO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: Skm Ctrl
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: Skm Myf5-BKO
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3531628
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: eWAT Ctrl
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3531628
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: eWAT Myf5-BKO
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3582928
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: sWAT Ctrl
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Male
Emaps: EMAPS:3582928
Stage: TS28
Assay Id: MGI:7447276
Age: postnatal week 12
Specimen Label: sWAT Myf5-BKO
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7447257
Assay Type: RT-PCR
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:7447278
Age: embryonic day 16.5
Specimen Label: E16.5 Ctrl
Detected: true
Specimen Num: 1