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Search results 1 to 100 out of 593 for Btg2

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: BTG2 is a member of the BTG/Tob family. It plays an important role in cellular differentiation and cancer. It is a direct transcriptional target of p53 and has been shown to be a major effector of suppression of Ras-induced transformation by p53 []. BTG2 has been shown to function as a transcription cofactor []. BTG2 is also found to interact directly with the first RRM domain of the poly(A)-binding protein PABPC1 and promoted mRNA poly(A) tail shortening []. In mice, its overexpression during neurogenesis led to microcephaly, while its deletion triggered impaired neuronal differentiation [].The BTG/Tob family members contain an conserved N-terminal domain, known as APRO domain (AntiPROliferative) or BTG domain. In mammals, six family members have been identified: BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. They interact with CAF1, a subunit of the CCR4-NOT complex. They display antiproliferative properties as their ectopic expression in a variety of cell lines reduced cell proliferation [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
Publication  
First Author: Stupfler B
Year: 2016
Journal: Nat Commun
Title: BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation.
Volume: 7
Pages: 10811
Publication
First Author: Boiko AD
Year: 2006
Journal: Genes Dev
Title: A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation.
Volume: 20
Issue: 2
Pages: 236-52
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:1063233
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825985
Age: embryonic day 14.5
Image: Additional file 4 Btg2
Specimen Label: Additional file 4 Btg2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1063233
Assay Type: RNA in situ
Annotation Date: 2009-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354995
Age: embryonic day 14.5
Image: 3C - Btg2
Specimen Label: 3C - Btg2
Detected: true
Specimen Num: 1
Publication
First Author: Prévôt D
Year: 2000
Journal: J Biol Chem
Title: The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation.
Volume: 275
Issue: 1
Pages: 147-53
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
Publication
First Author: Winkler GS
Year: 2010
Journal: J Cell Physiol
Title: The mammalian anti-proliferative BTG/Tob protein family.
Volume: 222
Issue: 1
Pages: 66-72
Publication
First Author: Fletcher BS
Year: 1991
Journal: J Biol Chem
Title: Structure and expression of TIS21, a primary response gene induced by growth factors and tumor promoters.
Volume: 266
Issue: 22
Pages: 14511-8
Publication
First Author: Hwang SS
Year: 2020
Journal: Science
Title: mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence.
Volume: 367
Issue: 6483
Pages: 1255-1260
Publication
First Author: Mauxion F
Year: 2008
Journal: EMBO J
Title: The BTG2 protein is a general activator of mRNA deadenylation.
Volume: 27
Issue: 7
Pages: 1039-48
Publication  
First Author: Velayutham N
Year: 2023
Journal: J Mol Cell Cardiol
Title: Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest.
Volume: 179
Pages: 30-41
Publication
First Author: Tijchon E
Year: 2015
Journal: PLoS One
Title: Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton.
Volume: 10
Issue: 7
Pages: e0131481
UniProt Feature
Begin: 1
Description: Protein BTG2
Type: chain
End: 158
Publication
First Author: Kim Y
Year: 2014
Journal: FEBS Lett
Title: C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression.
Volume: 588
Issue: 4
Pages: 625-31
Publication
First Author: Terra R
Year: 2008
Journal: Int Immunol
Title: Tissue-specific expression of B-cell translocation gene 2 (BTG2) and its function in T-cell immune responses in a transgenic mouse model.
Volume: 20
Issue: 3
Pages: 317-26
Publication
First Author: Bestepe F
Year: 2024
Journal: FASEB J
Title: MicroRNA-409-3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice.
Volume: 38
Issue: 3
Pages: e23459
Publication
First Author: Suzuki K
Year: 2021
Journal: J Neuroinflammation
Title: Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion.
Volume: 18
Issue: 1
Pages: 86
Publication
First Author: Dolezal E
Year: 2017
Journal: Nat Immunol
Title: The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.
Volume: 18
Issue: 8
Pages: 911-920
Publication
First Author: Park S
Year: 2004
Journal: Mol Cell Biol
Title: B-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signaling.
Volume: 24
Issue: 23
Pages: 10256-62
Publication
First Author: Guéhenneux F
Year: 1997
Journal: Leukemia
Title: Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle.
Volume: 11
Issue: 3
Pages: 370-5
Publication
First Author: Kim YD
Year: 2014
Journal: Diabetes
Title: B-cell translocation gene 2 regulates hepatic glucose homeostasis via induction of orphan nuclear receptor Nur77 in diabetic mouse model.
Volume: 63
Issue: 6
Pages: 1870-80
Publication
First Author: Lorda-Diez CI
Year: 2015
Journal: Aging (Albany NY)
Title: Apoptosis during embryonic tissue remodeling is accompanied by cell senescence.
Volume: 7
Issue: 11
Pages: 974-85
Publication
First Author: Kelly SM
Year: 2018
Journal: Neuron
Title: Radial Glial Lineage Progression and Differential Intermediate Progenitor Amplification Underlie Striatal Compartments and Circuit Organization.
Volume: 99
Issue: 2
Pages: 345-361.e4
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Taverna E
Year: 2011
Journal: Nat Neurosci
Title: A new approach to manipulate the fate of single neural stem cells in tissue.
Volume: 15
Issue: 2
Pages: 329-37
Publication
First Author: Haubensak W
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis.
Volume: 101
Issue: 9
Pages: 3196-201
Publication    
First Author: Mora-Bermúdez F
Year: 2016
Journal: Elife
Title: Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development.
Volume: 5
Publication
First Author: Aprea J
Year: 2013
Journal: EMBO J
Title: Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment.
Volume: 32
Issue: 24
Pages: 3145-60
Publication
First Author: Attardo A
Year: 2008
Journal: PLoS One
Title: Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progeny.
Volume: 3
Issue: 6
Pages: e2388
Publication  
First Author: Dori M
Year: 2020
Journal: Development
Title: MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis.
Volume: 147
Issue: 9
Publication
First Author: Albert M
Year: 2017
Journal: EMBO J
Title: Epigenome profiling and editing of neocortical progenitor cells during development.
Volume: 36
Issue: 17
Pages: 2642-2658
Publication  
First Author: Noack F
Year: 2019
Journal: Life Sci Alliance
Title: Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis.
Volume: 2
Issue: 2
Publication
First Author: Ryu MS
Year: 2014
Journal: Exp Cell Res
Title: Accumulation of cytolytic CD8+ T cells in B16-melanoma and proliferation of mature T cells in TIS21-knockout mice after T cell receptor stimulation.
Volume: 327
Issue: 2
Pages: 209-21
Publication
First Author: Canzoniere D
Year: 2004
Journal: J Neurosci
Title: Dual control of neurogenesis by PC3 through cell cycle inhibition and induction of Math1.
Volume: 24
Issue: 13
Pages: 3355-69
Publication
First Author: Farioli-Vecchioli S
Year: 2007
Journal: FASEB J
Title: Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.
Volume: 21
Issue: 9
Pages: 2215-25
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2654250
Age: embryonic day 7.0
Specimen Label: E1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2654250
Age: embryonic day 14.0
Specimen Label: E2
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: Br
Specimen Num: 3
GXD Expression        
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: Ht
Specimen Num: 4
GXD Expression        
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3287427
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: In
Specimen Num: 5
GXD Expression        
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: Ki
Specimen Num: 6
GXD Expression        
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: Li
Specimen Num: 7
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:2654250
Age: postnatal newborn
Specimen Label: Lu
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Br
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Ki
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Li
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Lu
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Mu
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Sp
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: St
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2654254
Age: postnatal week 4
Specimen Label: Thy
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:2654256
Age: postnatal newborn
Specimen Label: 0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2654256
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2654256
Age: postnatal week 4
Specimen Label: 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2654256
Age: postnatal week 8
Specimen Label: 8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2654256
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2654258
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2654258
Age: postnatal week 4
Specimen Label: 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2654258
Age: postnatal week 8
Specimen Label: 8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2654258
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876827
Stage: TS27
Assay Id: MGI:2654260
Age: postnatal newborn
Specimen Label: 0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2654260
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2654260
Age: postnatal week 4
Specimen Label: 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2654260
Age: postnatal week 8
Specimen Label: 8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2654260
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598827
Stage: TS27
Assay Id: MGI:2654261
Age: postnatal newborn
Specimen Label: 0
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2654261
Age: postnatal week 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:36197
Assay Type: Northern blot
Annotation Date: 2003-04-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2654261
Age: postnatal week 4
Specimen Label: 4
Detected: false
Specimen Num: 3