|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 103 for Btn1a1

<< First    < Previous  |  Next >    Last >>
0.033s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
696 | BTN1A1
Type: gene
Organism: human
•
•
•
•
•
Gene
100127740 | btn1a1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
306956 | Btn1a1
Type: gene
Organism: rat
•
•
•
•
•
Gene
471892 | BTN1A1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
282157 | BTN1A1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100855656 | BTN1A1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
420061 | BTN1A1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
700608 | BTN1A1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:103118 | Btn1a1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
19531472 | J:153458
First Author: Jeong J
Year: 2009
Journal: J Biol Chem
Title: The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues.
Volume: 284
Issue: 33
Pages: 22444-56
•
•
•
•
•
Publication
34938960 | J:321944
First Author: Jeong J
Year: 2021
Journal: FASEB Bioadv
Title: The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.
Volume: 3
Issue: 12
Pages: 971-997
•
•
•
•
•
Publication
15226505 | J:91440
First Author: Ogg SL
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets.
Volume: 101
Issue: 27
Pages: 10084-9
•
•
•
•
•
Publication
20208008 | J:160063
First Author: Smith IA
Year: 2010
Journal: J Immunol
Title: BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.
Volume: 184
Issue: 7
Pages: 3514-25
•
•
•
•
•
Publication
21915327 | J:177888
First Author: LaRocca J
Year: 2011
Journal: PLoS One
Title: Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1.
Volume: 6
Issue: 9
Pages: e24432
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0018314 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0020342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0020299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0020271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0020285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0020094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_103118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0020730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0019616 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0020045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0020171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0020159 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0020244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0020189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0020760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0019371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0019672 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0019377 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0019182 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
8995761 | J:37438
First Author: Ogg SL
Year: 1996
Journal: Mamm Genome
Title: Structural organization and mammary-specific expression of the butyrophilin gene.
Volume: 7
Issue: 12
Pages: 900-5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509630
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506930
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539895
Age: embryonic day 15.5
Image: GUDMAP:6306
Specimen Label: GUDMAP:6306
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1397102
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1786923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823519
Age: embryonic day 14.5
Image: euxassay_004383_12
Specimen Label: euxassay_004383_12
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1397102
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1786923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823519
Age: embryonic day 14.5
Image: euxassay_004383_13
Specimen Label: euxassay_004383_13
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1397102
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1786923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823519
Age: embryonic day 14.5
Image: euxassay_004383_14
Specimen Label: euxassay_004383_14
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1397102
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1786923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823519
Age: embryonic day 14.5
Image: euxassay_004383_15
Specimen Label: euxassay_004383_15
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
8759118 | J:34335
First Author: Taylor C
Year: 1996
Journal: Anim Genet
Title: Restriction fragment length polymorphism in amplification products of the bovine butyrophilin gene: assignment of bovine butyrophilin to bovine chromosome 23.
Volume: 27
Issue: 3
Pages: 183-5
•
•
•
•
•
Publication
8541302 | J:30255
First Author: Ishii T
Year: 1995
Journal: Biochim Biophys Acta
Title: Carboxy-terminal cytoplasmic domain of mouse butyrophilin specifically associates with a 150-kDa protein of mammary epithelial cells and milk fat globule membrane.
Volume: 1245
Issue: 3
Pages: 285-92
•
•
•
•
•
Publication
8530056 | J:28029
First Author: Jenkins NA
Year: 1995
Journal: Genomics
Title: Amphiphysin (Amph) maps to the proximal region of mouse chromosome 13.
Volume: 28
Issue: 2
Pages: 363-5
•
•
•
•
•
Publication
9101712 | J:39205
First Author: Aoki N
Year: 1997
Journal: Biochim Biophys Acta
Title: Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein.
Volume: 1334
Issue: 2-3
Pages: 182-90
•
•
•
•
•
Publication
11641716 | J:71411
First Author: Arkell RM
Year: 2001
Journal: Mamm Genome
Title: Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse.
Volume: 12
Issue: 9
Pages: 687-94
•
•
•
•
•
Publication
7782091 | J:23895
First Author: Amadou C
Year: 1995
Journal: Genomics
Title: Localization of new genes and markers to the distal part of the human major histocompatibility complex (MHC) region and comparison with the mouse: new insights into the evolution of mammalian genomes.
Volume: 26
Issue: 1
Pages: 9-20
•
•
•
•
•
Publication
26525672 | J:227703
First Author: Garside VC
Year: 2015
Journal: Development
Title: SOX9 modulates the expression of key transcription factors required for heart valve development.
Volume: 142
Issue: 24
Pages: 4340-50
•
•
•
•
•
Publication
9096311 | J:39275
First Author: Rattner A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
Volume: 94
Issue: 7
Pages: 2859-63
•
•
•
•
•
Publication
21820362 | J:175843
First Author: Lee FY
Year: 2011
Journal: Dev Cell
Title: Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.
Volume: 21
Issue: 2
Pages: 315-27
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
31953403 | J:285640
First Author: Zhao L
Year: 2020
Journal: Nat Commun
Title: TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh.
Volume: 11
Issue: 1
Pages: 341
•
•
•
•
•
Publication
35041644 | J:322517
First Author: Lu Y
Year: 2022
Journal: PLoS Biol
Title: Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR.
Volume: 20
Issue: 1
Pages: e3001518
•
•
•
•
•
Allele
Btn1a1<em1Smoc> | MGI:7288540
Name: butyrophilin, subfamily 1, member A1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
HT Experiment
GSE182075 | The butyrophilin 1a1 knock-out mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Strain
MGI:6428254 | C57BL/6JSmoc-Btn1a1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Publication
17785817 | -
First Author: Malcherek G
Year: 2007
Journal: J Immunol
Title: The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.
Volume: 179
Issue: 6
Pages: 3804-11
•
•
•
•
•
Protein Domain
IPR037958 | SPRY/PRY_BTN1/2
Type: Domain
Description: This domain, consisting of the distinct N-terminal PRY subdomain followed by the SPRY subdomain, is found at the C terminus of butyrophilin family 1A and 2A (BTN1A and BTN2A). BTNs belong to receptor glycoproteins of immunoglobulin (Ig) superfamily, characterized by the presence of extracellular Ig-like domains (IgV and/or IgC). BTN1A plays a role in the secretion, formation and stabilization of milk fat globules. The B30.2 domain of BTN1A1 binds the enzyme xanthine oxidoreductase (XOR) in order to participate in milk fat globule secretion; this interaction may lead to the production of reactive oxygen species, which have immunomodulatory and antimicrobial functions []. Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3 []. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens []. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.
•
•
•
•
•
Publication
23000944 | -
First Author: Afrache H
Year: 2012
Journal: Immunogenetics
Title: The butyrophilin (BTN) gene family: from milk fat to the regulation of the immune response.
Volume: 64
Issue: 11
Pages: 781-94
•
•
•
•
•
Protein
A4QPC6
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
•
•
•
•
•
Protein
B9EJ60
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom