| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
6621 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360411 |
|
| Stage: |
TS01 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 0.5 |
| Image: |
1 |
|
| Specimen Label: |
zygote |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360422 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 1.0 |
| Image: |
1 |
|
| Specimen Label: |
2-cell |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360433 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 2.0 |
| Image: |
1 |
|
| Specimen Label: |
4-cell |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360443 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 2.5 |
| Image: |
1 |
|
| Specimen Label: |
8-cell |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360464 |
|
| Stage: |
TS04 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 3.5 |
| Image: |
1 |
|
| Specimen Label: |
blastocyst |
|
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360411 |
|
| Stage: |
TS01 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 0.5 |
| Image: |
1 |
|
| Specimen Label: |
zygote |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360422 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 1.0 |
| Image: |
1 |
|
| Specimen Label: |
2-cell |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360433 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 2.0 |
| Image: |
1 |
|
| Specimen Label: |
4-cell |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360443 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 2.5 |
| Image: |
1 |
|
| Specimen Label: |
8-cell |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360464 |
|
| Stage: |
TS04 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 3.5 |
| Image: |
1 |
|
| Specimen Label: |
blastocyst |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397285 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360453 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398133 |
| Age: |
embryonic day 3.0 |
| Image: |
1 |
|
| Specimen Label: |
morula |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360453 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:7398135 |
| Age: |
embryonic day 3.0 |
| Image: |
1 |
|
| Specimen Label: |
morula |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-12-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:7397301 |
| Age: |
embryonic day 2.0 |
| Image: |
1c - 4-cell |
| Note: |
Expression is seen in the cytoplasm. |
| Specimen Label: |
1c - 4-cell |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-12-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318653 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:7397301 |
| Age: |
embryonic day 2.5 |
| Image: |
1c - 8-cell |
| Note: |
Expression is seen in the cytoplasm. |
| Specimen Label: |
1c - 8-cell |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-12-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360354 |
| Pattern: |
Not Specified |
| Stage: |
TS04 |
| Assay Id: |
MGI:7397301 |
| Age: |
embryonic day 3.5 |
| Image: |
1c - blastocyst |
| Note: |
Expression is seen in the cytoplasm. |
| Specimen Label: |
1c - blastocyst |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-12-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160403 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:7397301 |
| Age: |
embryonic day 3.0 |
| Image: |
1c - morula |
| Note: |
Expression is seen in the cytoplasm. |
| Specimen Label: |
1c - morula |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7397288 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-12-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
| Pattern: |
Not Specified |
| Stage: |
TS02 |
| Assay Id: |
MGI:7397301 |
| Age: |
embryonic day 1.0 |
| Image: |
1c - 2-cell |
| Note: |
Expression is seen in the cytoplasm. |
| Specimen Label: |
1c - 2-cell |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shen ZJ |
| Year: |
2021 |
| Journal: |
Cells |
| Title: |
Pin1 Regulates IL-5 Induced Eosinophil Polarization and Migration. |
| Volume: |
10 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki N |
| Year: |
2002 |
| Journal: |
DNA Res |
| Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
| Volume: |
9 |
| Issue: |
5 |
| Pages: |
179-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cobellis G |
| Year: |
2005 |
| Journal: |
Nucleic Acids Res |
| Title: |
Tagging genes with cassette-exchange sites. |
| Volume: |
33 |
| Issue: |
4 |
| Pages: |
e44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2001 |
|
| Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2012 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Loughran G |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection. |
| Volume: |
13 |
| Issue: |
2 |
| Pages: |
e0192648 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiou J |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
14624 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu M |
| Year: |
2006 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Alternative 3' UTR polyadenylation of Bzw1 transcripts display differential translation efficiency and tissue-specific expression. |
| Volume: |
345 |
| Issue: |
1 |
| Pages: |
479-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong DJ |
| Year: |
2009 |
| Journal: |
BMC Dev Biol |
| Title: |
A eukaryotic initiation factor 5C is upregulated during metamorphosis in the cotton bollworm, Helicoverpa armigera. |
| Volume: |
9 |
|
| Pages: |
19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee S |
| Year: |
2007 |
| Journal: |
Development |
| Title: |
The F-actin-microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion. |
| Volume: |
134 |
| Issue: |
9 |
| Pages: |
1767-77 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The eIF5-mimic protein 1/2 (also known as basic leucine zipper and W2 domain-containing proteins 2 and 1 (BZW2 and BZW1), respectively), are paralogous human proteins containing C-terminal HEAT domains that resemble the HEAT domain of eIF5 []. BZW1 plays an important role in the cell cycle and transcriptionally control the histone H4 gene during G1/S phase []. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal W2 domain resembles that of a set of concatenated HEAT repeats [, , ].The W2 domain has a globular fold and is exclusively composed out of α-helices [, , ]. The structure can be divided into a structural C-terminalcore onto which the two N-terminal helices are attached. The core contains two aromatic/acidic residue-rich regions (AA boxes), which are important for mediating protein-protein interactions. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boesen T |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue. |
| Volume: |
279 |
| Issue: |
11 |
| Pages: |
10584-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei Z |
| Year: |
2006 |
| Journal: |
J Mol Biol |
| Title: |
Crystal structure of the C-terminal domain of S.cerevisiae eIF5. |
| Volume: |
359 |
| Issue: |
1 |
| Pages: |
1-9 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
419
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
419
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
419
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
451
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bieniossek C |
| Year: |
2006 |
| Journal: |
J Mol Biol |
| Title: |
The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. |
| Volume: |
360 |
| Issue: |
2 |
| Pages: |
457-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aravind L |
| Year: |
2000 |
| Journal: |
Genome Res |
| Title: |
Eukaryote-specific domains in translation initiation factors: implications for translation regulation and evolution of the translation system. |
| Volume: |
10 |
| Issue: |
8 |
| Pages: |
1172-84 |
|
•
•
•
•
•
|