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Search results 1 to 100 out of 338 for C1qa

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kumari R
Year: 2015
Journal: PLoS One
Title: Differential Effects of C1qa Ablation on Glaucomatous Damage in Two Sexes in DBA/2NNia Mice.
Volume: 10
Issue: 11
Pages: e0142199
GXD Expression
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2020-09-23
Strength: Present
Sex: Male
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6456803
Age: embryonic day 18.5
Image: S13
Note: C1qa is a microglial marker.
Specimen Label: S13
Detected: true
Specimen Num: 1
Publication
First Author: Fonseca MI
Year: 2017
Journal: J Neuroinflammation
Title: Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain.
Volume: 14
Issue: 1
Pages: 48
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189888
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - C1qa
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189888
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - C1qa
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189888
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - C1qa
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189888
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - C1qa
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189888
Age: postnatal day 4
Specimen Label: Table S2 - P4 - C1qa
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189888
Age: postnatal day 14
Specimen Label: Table S2 - P14 - C1qa
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6168726
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189888
Age: postnatal day 28
Specimen Label: Table S2 - P28 - C1qa
Detected: true
Specimen Num: 7
Publication
First Author: Mitchell DA
Year: 2002
Journal: J Immunol
Title: C1q deficiency and autoimmunity: the effects of genetic background on disease expression.
Volume: 168
Issue: 5
Pages: 2538-43
Publication
First Author: Hammond JW
Year: 2018
Journal: Glia
Title: HIV Tat causes synapse loss in a mouse model of HIV-associated neurocognitive disorder that is independent of the classical complement cascade component C1q.
Volume: 66
Issue: 12
Pages: 2563-2574
Publication  
First Author: Williams PA
Year: 2016
Journal: Mol Neurodegener
Title: Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma.
Volume: 11
Pages: 26
Publication
First Author: Naito AT
Year: 2012
Journal: Cell
Title: Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.
Volume: 149
Issue: 6
Pages: 1298-313
Publication  
First Author: Donat C
Year: 2020
Journal: Front Immunol
Title: Complement C1q Enhances Primary Hemostasis.
Volume: 11
Pages: 1522
Publication
First Author: Lui H
Year: 2016
Journal: Cell
Title: Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Volume: 165
Issue: 4
Pages: 921-35
Publication
First Author: Jiao H
Year: 2018
Journal: Mol Neurodegener
Title: Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration.
Volume: 13
Issue: 1
Pages: 45
Publication
First Author: Xavier S
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.
Volume: 312
Issue: 3
Pages: F516-F532
Publication
First Author: Tong HH
Year: 2010
Journal: Infect Immun
Title: Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2.
Volume: 78
Issue: 3
Pages: 976-83
Publication
First Author: Tong HH
Year: 2014
Journal: PLoS One
Title: Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice.
Volume: 9
Issue: 4
Pages: e95160
Publication
First Author: Miura-Shimura Y
Year: 2002
Journal: J Immunol
Title: C1q regulatory region polymorphism down-regulating murine c1q protein levels with linkage to lupus nephritis.
Volume: 169
Issue: 3
Pages: 1334-9
Publication  
First Author: Graham LC
Year: 2020
Journal: eNeuro
Title: Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity.
Volume: 7
Issue: 3
Publication    
First Author: Pendse M
Year: 2023
Journal: Elife
Title: Macrophages regulate gastrointestinal motility through complement component 1q.
Volume: 12
Publication
First Author: Soto I
Year: 2015
Journal: PLoS Biol
Title: APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.
Volume: 13
Issue: 10
Pages: e1002279
Publication
First Author: Hillian AD
Year: 2013
Journal: J Biol Chem
Title: Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis.
Volume: 288
Issue: 31
Pages: 22565-75
Publication
First Author: Calton MA
Year: 2014
Journal: PLoS One
Title: A lack of immune system genes causes loss in high frequency hearing but does not disrupt cochlear synapse maturation in mice.
Volume: 9
Issue: 5
Pages: e94549
Publication
First Author: Zhang J
Year: 2020
Journal: Nature
Title: Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Volume: 588
Issue: 7838
Pages: 459-465
Publication
First Author: Heidari Y
Year: 2006
Journal: Genes Immun
Title: Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus.
Volume: 7
Issue: 7
Pages: 592-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cheng TW
Year: 2010
Journal: J Neurosci
Title: Emergence of lamina-specific retinal ganglion cell connectivity by axon arbor retraction and synapse elimination.
Volume: 30
Issue: 48
Pages: 16376-82
Publication
First Author: Manderson AP
Year: 2006
Journal: J Immunol
Title: A novel mechanism for complement activation at the surface of B cells following antigen binding.
Volume: 177
Issue: 8
Pages: 5155-62
Publication
First Author: Fossati-Jimack L
Year: 2008
Journal: Mol Immunol
Title: C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice.
Volume: 45
Issue: 3
Pages: 787-95
Publication
First Author: Holden SS
Year: 2021
Journal: Science
Title: Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury.
Volume: 373
Issue: 6560
Pages: eabj2685
Publication
First Author: Li M
Year: 2008
Journal: Mol Immunol
Title: Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation.
Volume: 45
Issue: 11
Pages: 3244-52
Publication  
First Author: Visciano ML
Year: 2021
Journal: Viruses
Title: Antibodies Elicited in Response to a Single Cycle Glycoprotein D Deletion Viral Vaccine Candidate Bind C1q and Activate Complement Mediated Neutralization and Cytolysis.
Volume: 13
Issue: 7
Publication
First Author: Thompson CD
Year: 2023
Journal: mBio
Title: Oligopeptide Transporters of Nonencapsulated Streptococcus pneumoniae Regulate CbpAC and PspA Expression and Reduce Complement-Mediated Clearance.
Volume: 14
Issue: 1
Pages: e0332522
Publication  
First Author: Ogawa T
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Complement protein C1q activates lung fibroblasts and exacerbates silica-induced pulmonary fibrosis in mice.
Volume: 603
Pages: 88-93
Publication
First Author: Botto M
Year: 1998
Journal: Nat Genet
Title: Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies.
Volume: 19
Issue: 1
Pages: 56-9
Publication
First Author: Ferry H
Year: 2007
Journal: J Immunol
Title: Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.
Volume: 178
Issue: 5
Pages: 2916-22
Publication
First Author: Nash JT
Year: 2001
Journal: Clin Exp Immunol
Title: Immune complex processing in C1q-deficient mice.
Volume: 123
Issue: 2
Pages: 196-202
Publication
First Author: Botto M
Year: 1998
Journal: Exp Clin Immunogenet
Title: C1q knock-out mice for the study of complement deficiency in autoimmune disease.
Volume: 15
Issue: 4
Pages: 231-4
Publication
First Author: Pickering MC
Year: 2001
Journal: J Invest Dermatol
Title: Ultraviolet-radiation-induced keratinocyte apoptosis in C1q-deficient mice.
Volume: 117
Issue: 1
Pages: 52-8
Publication
First Author: Bossi F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: C1q as a unique player in angiogenesis with therapeutic implication in wound healing.
Volume: 111
Issue: 11
Pages: 4209-14
Publication
First Author: Cutler AJ
Year: 2001
Journal: Eur J Immunol
Title: Intact B cell tolerance in the absence of the first component of the classical complement pathway.
Volume: 31
Issue: 7
Pages: 2087-93
Publication
First Author: Cutler AJ
Year: 1998
Journal: J Exp Med
Title: T cell-dependent immune response in C1q-deficient mice: defective interferon gamma production by antigen-specific T cells.
Volume: 187
Issue: 11
Pages: 1789-97
Publication
First Author: Ten VS
Year: 2005
Journal: Stroke
Title: C1q-deficiency is neuroprotective against hypoxic-ischemic brain injury in neonatal mice.
Volume: 36
Issue: 10
Pages: 2244-50
Publication
First Author: Cortes-Hernandez J
Year: 2004
Journal: Eur J Immunol
Title: Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice.
Volume: 34
Issue: 12
Pages: 3713-22
Publication
First Author: Fonseca MI
Year: 2004
Journal: J Neurosci
Title: Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease.
Volume: 24
Issue: 29
Pages: 6457-65
Publication
First Author: Trendelenburg M
Year: 2004
Journal: Immunology
Title: Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice.
Volume: 113
Issue: 1
Pages: 80-8
Publication
First Author: Sutton EF
Year: 2020
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Paternal deficiency of complement component C1q leads to a preeclampsia-like pregnancy in wild-type female mice and vascular adaptations postpartum.
Volume: 318
Issue: 6
Pages: R1047-R1057
Publication
First Author: Shah D
Year: 2015
Journal: J Biol Chem
Title: C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Volume: 290
Issue: 49
Pages: 29642-51
Publication
First Author: Chu Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Enhanced synaptic connectivity and epilepsy in C1q knockout mice.
Volume: 107
Issue: 17
Pages: 7975-80
Publication
First Author: Galvan MD
Year: 2008
Journal: J Neurosci
Title: Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury.
Volume: 28
Issue: 51
Pages: 13876-88
Publication  
First Author: Belmonte B
Year: 2022
Journal: Front Immunol
Title: Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae.
Volume: 13
Pages: 882298
Publication
First Author: Peterson SL
Year: 2015
Journal: J Neurosci
Title: Complement protein C1q modulates neurite outgrowth in vitro and spinal cord axon regeneration in vivo.
Volume: 35
Issue: 10
Pages: 4332-49
Publication
First Author: Welsh CA
Year: 2020
Journal: J Neurosci
Title: Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q.
Volume: 40
Issue: 4
Pages: 769-783
Publication
First Author: Ten VS
Year: 2010
Journal: J Neurosci
Title: Complement component c1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury.
Volume: 30
Issue: 6
Pages: 2077-87
Publication
First Author: Singh J
Year: 2011
Journal: Hypertension
Title: Role of complement component C1q in the onset of preeclampsia in mice.
Volume: 58
Issue: 4
Pages: 716-24
GXD Expression    
Probe: MGI:7284393
Assay Type: RT-PCR
Annotation Date: 2022-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7284417
Age: embryonic day 18.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7284393
Assay Type: RT-PCR
Annotation Date: 2022-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7284417
Age: embryonic day 18.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2914820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7931
Specimen Label: GUDMAP:7931
Specimen Num: 2
GXD Expression  
Probe: MGI:1406697
Assay Type: RNA in situ
Annotation Date: 2017-08-09
Strength: Present
Sex: Female
Emaps: EMAPS:3150320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5906433
Age: embryonic day 12.5
Image: GUDMAP:21140
Specimen Label: GUDMAP:21140
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1797020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7931
Specimen Label: GUDMAP:7931
Specimen Num: 2
GXD Expression  
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7932
Note: signal on metanephroi likely to be associated mesentery
Specimen Label: GUDMAP:7932
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7933
Note: signal on metanephroi likely to be associated mesentery
Specimen Label: GUDMAP:7933
Detected: false
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692985
Age: postnatal adult
Image: JAX_1801079
Note: kidney
Specimen Label: JAX_1801079
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2893720
Pattern: Spotted
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7930
Note: single cell expression
Specimen Label: GUDMAP:7930
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795920
Pattern: Spotted
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7930
Note: single cell expression
Specimen Label: GUDMAP:7930
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2915820
Pattern: Spotted
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7931
Note: single cell expression
Specimen Label: GUDMAP:7931
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1736620
Pattern: Spotted
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7932
Note: single cell expression
Specimen Label: GUDMAP:7932
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5000934
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1736620
Pattern: Spotted
Stage: TS20
Assay Id: MGI:5541492
Age: embryonic day 12.5
Image: GUDMAP:7933
Note: single cell expression
Specimen Label: GUDMAP:7933
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7332759
Assay Type: RNA in situ
Annotation Date: 2022-08-30
Strength: Present
Sex: Female
Emaps: EMAPS:2962120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7332797
Age: embryonic day 12.5
Note: Expression is at the distal tip on either side of the distal urethral epithelium. There are no obvious differences between male and female expression patterns.
Specimen Label: 3A female
Detected: true
Specimen Num: 2