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Search results 1 to 100 out of 3561 for C3

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Cahen-Kramer Y
Year: 1994
Journal: J Exp Med
Title: The structure of an alternate form of complement C3 that displays costimulatory growth factor activity for B lymphocytes.
Volume: 180
Issue: 6
Pages: 2079-88
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Buono C
Year: 2002
Journal: Circulation
Title: Influence of C3 deficiency on atherosclerosis.
Volume: 105
Issue: 25
Pages: 3025-31
Publication
First Author: Peterson SL
Year: 2017
Journal: Sci Rep
Title: Complement Protein C3 Suppresses Axon Growth and Promotes Neuron Loss.
Volume: 7
Issue: 1
Pages: 12904
Publication
First Author: Bauer EM
Year: 2011
Journal: PLoS One
Title: Complement C3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice.
Volume: 6
Issue: 12
Pages: e28578
Publication  
First Author: Gorelik A
Year: 2018
Journal: Front Mol Neurosci
Title: Complement C3 Affects Rac1 Activity in the Developing Brain.
Volume: 11
Pages: 150
Publication
First Author: Welch TR
Year: 2005
Journal: Clin Immunol
Title: C3 is central to the interstitial component of experimental immune complex glomerulonephritis.
Volume: 115
Issue: 1
Pages: 80-4
Publication
First Author: Ehrnthaller C
Year: 2013
Journal: PLoS One
Title: Complement C3 and C5 deficiency affects fracture healing.
Volume: 8
Issue: 11
Pages: e81341
Publication
First Author: Verschoor A
Year: 2003
Journal: J Immunol
Title: Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection.
Volume: 171
Issue: 10
Pages: 5363-71
Publication
First Author: Tsoni SV
Year: 2009
Journal: Infect Immun
Title: Complement C3 plays an essential role in the control of opportunistic fungal infections.
Volume: 77
Issue: 9
Pages: 3679-85
Publication
First Author: Sheerin NS
Year: 2008
Journal: FASEB J
Title: Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury.
Volume: 22
Issue: 4
Pages: 1065-72
Publication
First Author: Guo Q
Year: 2010
Journal: Neurosci Lett
Title: Effects of C3 deficiency on inflammation and regeneration following spinal cord injury in mice.
Volume: 485
Issue: 1
Pages: 32-6
Publication
First Author: Natoli R
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration.
Volume: 58
Issue: 7
Pages: 2977-2990
Publication
First Author: Farrar CA
Year: 2006
Journal: FASEB J
Title: Local extravascular pool of C3 is a determinant of postischemic acute renal failure.
Volume: 20
Issue: 2
Pages: 217-26
Publication
First Author: Mocco J
Year: 2006
Journal: Circ Res
Title: Complement component C3 mediates inflammatory injury following focal cerebral ischemia.
Volume: 99
Issue: 2
Pages: 209-17
Publication
First Author: Sorbara MT
Year: 2018
Journal: Cell Host Microbe
Title: Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria.
Volume: 23
Issue: 5
Pages: 644-652.e5
Publication
First Author: Gao X
Year: 2011
Journal: Clin Immunol
Title: Complement C3 deficiency prevent against the onset of streptozotocin-induced autoimmune diabetes involving expansion of regulatory T cells.
Volume: 140
Issue: 3
Pages: 236-43
Publication
First Author: Peng Q
Year: 2006
Journal: J Immunol
Title: Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype.
Volume: 176
Issue: 6
Pages: 3330-41
Publication
First Author: O'Brien KB
Year: 2011
Journal: PLoS One
Title: A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection.
Volume: 6
Issue: 3
Pages: e17377
Publication
First Author: Springall T
Year: 2001
Journal: Nat Med
Title: Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.
Volume: 7
Issue: 7
Pages: 801-6
Publication
First Author: Giacomassi C
Year: 2017
Journal: J Invest Dermatol
Title: Complement C3 Exacerbates Imiquimod-Induced Skin Inflammation and Psoriasiform Dermatitis.
Volume: 137
Issue: 3
Pages: 760-763
Publication
First Author: Paglialunga S
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice.
Volume: 294
Issue: 3
Pages: E521-9
Publication
First Author: Kenyon KD
Year: 2011
Journal: J Immunol
Title: IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity.
Volume: 187
Issue: 5
Pages: 2101-11
Publication
First Author: Domdey H
Year: 1982
Journal: Proc Natl Acad Sci U S A
Title: Characterization of the mRNA and cloned cDNA specifying the third component of mouse complement.
Volume: 79
Issue: 24
Pages: 7619-23
Publication
First Author: Kopf M
Year: 1998
Journal: J Exp Med
Title: Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component.
Volume: 188
Issue: 10
Pages: 1895-906
Publication  
First Author: Shi Q
Year: 2017
Journal: Sci Transl Med
Title: Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
Volume: 9
Issue: 392
Publication
First Author: Xia Z
Year: 2002
Journal: J Biol Chem
Title: Acylation-stimulating protein (ASP) deficiency induces obesity resistance and increased energy expenditure in ob/ob mice.
Volume: 277
Issue: 48
Pages: 45874-9
Publication
First Author: Coles B
Year: 2007
Journal: Immunology
Title: CD59 or C3 are not requred for angiotensin II-dependent hypertension or hypertrophy in mice.
Volume: 121
Issue: 4
Pages: 518-25
Publication
First Author: Goldman MB
Year: 1992
Journal: Eur J Immunol
Title: T lymphocytes mediate immunologic control of C3 gene expression.
Volume: 22
Issue: 12
Pages: 3103-9
Publication
First Author: Woods KM
Year: 2011
Journal: J Immunol
Title: CR2+ marginal zone B cell production of pathogenic natural antibodies is C3 independent.
Volume: 186
Issue: 3
Pages: 1755-62
Publication
First Author: Lin M
Year: 2010
Journal: Diabetes
Title: Immune cell-derived c3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin.
Volume: 59
Issue: 9
Pages: 2247-52
Publication
First Author: Harder JM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.
Volume: 114
Issue: 19
Pages: E3839-E3848
Publication
First Author: Fu H
Year: 2012
Journal: Glia
Title: Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia.
Volume: 60
Issue: 6
Pages: 993-1003
Publication
First Author: Kopf M
Year: 2002
Journal: Nat Med
Title: Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection.
Volume: 8
Issue: 4
Pages: 373-8
Publication
First Author: Han R
Year: 2010
Journal: J Clin Invest
Title: Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice.
Volume: 120
Issue: 12
Pages: 4366-74
Publication
First Author: Flierl MA
Year: 2008
Journal: FASEB J
Title: Functions of the complement components C3 and C5 during sepsis.
Volume: 22
Issue: 10
Pages: 3483-90
Publication
First Author: Müller-Calleja N
Year: 2018
Journal: Blood Adv
Title: Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies.
Volume: 2
Issue: 9
Pages: 979-986
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Hoh Kam J
Year: 2013
Journal: Am J Pathol
Title: Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration.
Volume: 183
Issue: 2
Pages: 480-92
Publication
First Author: Leung VW
Year: 2009
Journal: Am J Pathol
Title: Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient mice.
Volume: 175
Issue: 4
Pages: 1757-67
Publication
First Author: Sohn JH
Year: 2003
Journal: Nat Med
Title: Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells.
Volume: 9
Issue: 2
Pages: 206-12
Publication
First Author: Baruah P
Year: 2010
Journal: Eur J Immunol
Title: Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance.
Volume: 40
Issue: 6
Pages: 1758-67
Publication
First Author: Circolo A
Year: 1999
Journal: Immunopharmacology
Title: Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA.
Volume: 42
Issue: 1-3
Pages: 135-49
Publication
First Author: Natsuume-Sakai S
Year: 1978
Journal: J Immunol
Title: Preparation of an alloantiserum to murine C3 and demonstration of multiple alleles.
Volume: 121
Issue: 5
Pages: 2025-9
Publication
First Author: Wessels MR
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.
Volume: 92
Issue: 25
Pages: 11490-4
GXD Expression  
Probe: MGI:5473641
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-10
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1604611
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5473685
Age: embryonic day 7.5
Note: No increased C3 deposition was noted in the trophectoderm.
Detected: true
Specimen Num: 4
Publication
First Author: Kerepesi LA
Year: 2006
Journal: J Immunol
Title: Complement component C3 is required for protective innate and adaptive immunity to larval strongyloides stercoralis in mice.
Volume: 176
Issue: 7
Pages: 4315-22
Publication
First Author: Rupprecht TA
Year: 2007
Journal: J Immunol
Title: Complement C1q and C3 are critical for the innate immune response to Streptococcus pneumoniae in the central nervous system.
Volume: 178
Issue: 3
Pages: 1861-9
Publication
First Author: Li J
Year: 2005
Journal: J Biol Chem
Title: Regulation of complement C3 expression by the bile acid receptor FXR.
Volume: 280
Issue: 9
Pages: 7427-34
Publication
First Author: Baudino L
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.
Volume: 111
Issue: 4
Pages: 1503-8
Publication
First Author: Natsuume-Sakai S
Year: 1979
Journal: J Immunol
Title: Genetic mapping of the locus controlling structural variations of murine C3 in the chromosome 17.
Volume: 123
Issue: 2
Pages: 947-8
Publication
First Author: Ratajczak J
Year: 2004
Journal: Blood
Title: Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow.
Volume: 103
Issue: 6
Pages: 2071-8
Publication
First Author: Clark A
Year: 2008
Journal: Mol Immunol
Title: Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.
Volume: 45
Issue: 11
Pages: 3125-32
Publication
First Author: Verschoor A
Year: 2001
Journal: J Immunol
Title: Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection.
Volume: 167
Issue: 5
Pages: 2446-51
Publication
First Author: Osmers I
Year: 2006
Journal: Mol Immunol
Title: Complement in BuB/BnJ mice revisited: serum C3 levels and complement opsonic activity are not elevated.
Volume: 43
Issue: 10
Pages: 1722-5
Publication
First Author: Szalai AJ
Year: 2007
Journal: Mol Immunol
Title: Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease.
Volume: 44
Issue: 12
Pages: 3132-6
Publication  
First Author: Kawamura N
Year: 1992
Journal: Biochem J
Title: Cis- and trans-acting elements required for constitutive and cytokine-regulated expression of the mouse complement C3 gene.
Volume: 283 ( Pt 3)
Pages: 705-12
Publication
First Author: Maier M
Year: 2008
Journal: J Neurosci
Title: Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.
Volume: 28
Issue: 25
Pages: 6333-41
Publication
First Author: Mershon-Shier KL
Year: 2011
Journal: Mol Immunol
Title: In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways.
Volume: 48
Issue: 15-16
Pages: 2009-18
Publication
First Author: Okamoto T
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.
Volume: 315
Issue: 1
Pages: L1-L10
Publication
First Author: Nakayama Y
Year: 2009
Journal: J Immunol
Title: C3 promotes expansion of CD8+ and CD4+ T cells in a Listeria monocytogenes infection.
Volume: 183
Issue: 5
Pages: 2921-31
Publication
First Author: Michel B
Year: 2013
Journal: Int Immunol
Title: Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.
Volume: 25
Issue: 12
Pages: 697-702
Publication
First Author: Sekine H
Year: 2001
Journal: J Immunol
Title: Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Volume: 166
Issue: 10
Pages: 6444-51
Publication
First Author: Ruseva MM
Year: 2009
Journal: Mol Immunol
Title: Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.
Volume: 46
Issue: 5
Pages: 803-11
Publication
First Author: Zhou J
Year: 2008
Journal: J Neurochem
Title: Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease.
Volume: 106
Issue: 5
Pages: 2080-92
Publication
First Author: Williams AL
Year: 2017
Journal: Kidney Int
Title: C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy.
Volume: 91
Issue: 6
Pages: 1386-1397
Publication
First Author: Paixão-Cavalcante D
Year: 2009
Journal: Mol Immunol
Title: Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase.
Volume: 46
Issue: 10
Pages: 1942-50
Publication
First Author: Fischer MB
Year: 1998
Journal: J Immunol
Title: Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice.
Volume: 160
Issue: 6
Pages: 2619-25
Publication
First Author: Bode J
Year: 2012
Journal: PLoS One
Title: A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci.
Volume: 7
Issue: 11
Pages: e50327
Publication
First Author: Williams JA
Year: 2016
Journal: PLoS One
Title: Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina.
Volume: 11
Issue: 8
Pages: e0161898
Publication
First Author: Lynch DM
Year: 1993
Journal: Eur J Immunogenet
Title: Studies on the structure of complement C3 and the stability of C3 derived phagocytic ligands C3b/iC3b in SJL/J and BALB/c mice.
Volume: 20
Issue: 1
Pages: 1-9
Publication
First Author: Read RW
Year: 2006
Journal: Exp Eye Res
Title: Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis.
Volume: 82
Issue: 3
Pages: 389-94
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Publication
First Author: Deng C
Year: 2002
Journal: J Immunol
Title: Resistance to experimental autoimmune myasthenia gravis in IL-6-deficient mice is associated with reduced germinal center formation and C3 production.
Volume: 169
Issue: 2
Pages: 1077-83
Publication
First Author: Ruseva MM
Year: 2014
Journal: Clin Exp Immunol
Title: C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.
Volume: 176
Issue: 1
Pages: 84-92
Publication
First Author: Wu T
Year: 2019
Journal: Cell Rep
Title: Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Volume: 28
Issue: 8
Pages: 2111-2123.e6
Publication
First Author: Smith SS
Year: 2008
Journal: Neurosci Lett
Title: Deletion of both ICAM-1 and C3 enhances severity of experimental autoimmune encephalomyelitis compared to C3-deficient mice.
Volume: 442
Issue: 2
Pages: 158-60
Publication
First Author: Natsuume-Sakai S
Year: 1978
Journal: J Immunol
Title: Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.
Volume: 121
Issue: 2
Pages: 491-8
Publication
First Author: Drouin SM
Year: 2001
Journal: J Immunol
Title: Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy.
Volume: 167
Issue: 8
Pages: 4141-5
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Rubinstein P
Year: 1979
Journal: J Immunol
Title: The location of the C3 and GLO (glyoxalase 1) loci of the IXth linkage group in mice.
Volume: 122
Issue: 6
Pages: 2584-9
Publication
First Author: Leinhase I
Year: 2006
Journal: Exp Neurol
Title: Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Volume: 199
Issue: 2
Pages: 454-64
Publication
First Author: Xing EM
Year: 2015
Journal: Mol Genet Metab
Title: The effect of Tlr4 and/or C3 deficiency and of neonatal gene therapy on skeletal disease in mucopolysaccharidosis VII mice.
Volume: 114
Issue: 2
Pages: 209-16
Publication
First Author: Mahesh J
Year: 1999
Journal: Shock
Title: Elucidation of the early events contributing to zymosan-induced multiple organ dysfunction syndrome using MIP-1alpha, C3 knockout, and C5-deficient mice.
Volume: 12
Issue: 5
Pages: 340-9
Publication
First Author: Mueller-Ortiz SL
Year: 2004
Journal: Infect Immun
Title: The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia.
Volume: 72
Issue: 5
Pages: 2899-906
Gene
Type: gene
Organism: Homo sapiens
GXD Expression
Probe: MGI:3041820
Assay Type: RNA in situ
Annotation Date: 2004-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1943326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3041849
Age: embryonic day 18.0
Image: 7C
Note: Expression was detected in cells in the region of ossification of the C3 body and surrounding mesenchymal cells.
Detected: true
Specimen Num: 5
Publication
First Author: Wysoczynski M
Year: 2014
Journal: Stem Cells
Title: Complement component 3 is necessary to preserve myocardium and myocardial function in chronic myocardial infarction.
Volume: 32
Issue: 9
Pages: 2502-15