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Search results 1 to 100 out of 375 for C5ar1

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Hits by Pathway

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Type Details Score
Gene
728 | C5AR1
Type: gene
Organism: human
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Gene
468931 | C5AR1
Type: gene
Organism: chimpanzee
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Gene
493645 | C5AR1
Type: gene
Organism: cattle
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Gene
430484 | C5AR1
Type: gene
Organism: chicken
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Gene
100000959 | c5ar1
Type: gene
Organism: zebrafish
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Gene
718056 | C5AR1
Type: gene
Organism: macaque, rhesus
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Gene
100379958 | c5ar1
Type: gene
Organism: frog, western clawed
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Gene
113959 | C5ar1
Type: gene
Organism: rat
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Gene
442974 | C5AR1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:88232 | C5ar1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28614388 | J:245607
First Author: Bergdolt S
Year: 2017
Journal: PLoS One
Title: Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing.
Volume: 12
Issue: 6
Pages: e0179512
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Publication
37104043 | J:338413
 
First Author: Silva BM
Year: 2023
Journal: J Clin Invest
Title: C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.
Volume: 133
Issue: 12
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Publication
32754267 | J:306845
First Author: Ding P
Year: 2020
Journal: Theranostics
Title: C5aR1 is a master regulator in Colorectal Tumorigenesis via Immune modulation.
Volume: 10
Issue: 19
Pages: 8619-8632
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Publication
32733463 | J:312582
 
First Author: Briukhovetska D
Year: 2020
Journal: Front Immunol
Title: C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.
Volume: 11
Pages: 1397
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Publication
36246887 | J:335314
 
First Author: Bülow JM
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
Volume: 13
Pages: 1016057
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Publication
27053686 | J:280616
First Author: Weiss S
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.
Volume: 310
Issue: 11
Pages: F1356-65
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Publication
25681535 | J:259398
 
First Author: Benson MJ
Year: 2015
Journal: Neurobiol Dis
Title: A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models.
Volume: 76
Pages: 87-97
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Publication
30106232 | J:280569
First Author: Llaudo I
Year: 2019
Journal: Am J Transplant
Title: C5aR1 regulates migration of suppressive myeloid cells required for costimulatory blockade-induced murine allograft survival.
Volume: 19
Issue: 3
Pages: 633-645
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Publication
31298935 | J:290942
First Author: Nabizadeh JA
Year: 2019
Journal: FASEB J
Title: C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma.
Volume: 33
Issue: 10
Pages: 11060-11071
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Publication
28923083 | J:313230
First Author: Hernandez MX
Year: 2017
Journal: Mol Neurodegener
Title: Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss.
Volume: 12
Issue: 1
Pages: 66
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Publication
25589074 | J:262501
First Author: Karsten CM
Year: 2015
Journal: J Immunol
Title: Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse.
Volume: 194
Issue: 4
Pages: 1841-55
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Publication
30634407 | J:295108
 
First Author: Jiang Y
Year: 2019
Journal: Viruses
Title: Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV.
Volume: 11
Issue: 1
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Publication
29348261 | J:275214
First Author: Natarajan N
Year: 2018
Journal: Circulation
Title: Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration.
Volume: 137
Issue: 20
Pages: 2152-2165
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Publication
31274379 | J:289416
First Author: Muenstermann M
Year: 2019
Journal: Virulence
Title: Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections.
Volume: 10
Issue: 1
Pages: 677-694
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Publication
28455369 | J:242692
First Author: Coulthard LG
Year: 2017
Journal: J Neurosci
Title: Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.
Volume: 37
Issue: 22
Pages: 5395-5407
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Publication
37726739 | J:340750
First Author: Petrisko TJ
Year: 2023
Journal: J Neuroinflammation
Title: Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models.
Volume: 20
Issue: 1
Pages: 211
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Publication
30294325 | J:294487
 
First Author: McCullough RL
Year: 2018
Journal: Front Immunol
Title: Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome.
Volume: 9
Pages: 2133
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Publication
29070810 | J:256336
First Author: Kovtun A
Year: 2017
Journal: Sci Rep
Title: Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair.
Volume: 7
Issue: 1
Pages: 14061
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Publication
32726800 | J:291890
     
First Author: Carvelli J
Year: 2020
Journal: Nature
Title: Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis.
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Publication
16980974 | J:292028
First Author: Lee H
Year: 2006
Journal: Nat Biotechnol
Title: Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies.
Volume: 24
Issue: 10
Pages: 1279-84
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Publication
22430734 | J:184056
First Author: Dunkelberger J
Year: 2012
Journal: J Immunol
Title: C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity.
Volume: 188
Issue: 8
Pages: 4032-42
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Publication
31447855 | J:281840
 
First Author: Zheng QY
Year: 2019
Journal: Front Immunol
Title: C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.
Volume: 10
Pages: 1866
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Publication
28231307 | J:246210
First Author: Ender F
Year: 2017
Journal: PLoS One
Title: Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase.
Volume: 12
Issue: 2
Pages: e0172446
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Publication
36434087 | J:334788
First Author: Coughlan MT
Year: 2022
Journal: Sci Rep
Title: Valproic acid attenuates cellular senescence in diabetic kidney disease through the inhibition of complement C5a receptors.
Volume: 12
Issue: 1
Pages: 20278
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Publication
22205026 | J:180756
First Author: Banda NK
Year: 2012
Journal: J Immunol
Title: Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.
Volume: 188
Issue: 3
Pages: 1469-78
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Publication
23420882 | J:194466
First Author: Denny KJ
Year: 2013
Journal: J Immunol
Title: C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice.
Volume: 190
Issue: 7
Pages: 3493-9
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Publication
30300579 | J:266018
First Author: Medler TR
Year: 2018
Journal: Cancer Cell
Title: Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy.
Volume: 34
Issue: 4
Pages: 561-578.e6
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Publication
23074214 | J:214214
First Author: Yu M
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: A novel role of complement in retinal degeneration.
Volume: 53
Issue: 12
Pages: 7684-92
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Publication
17322907 | J:279795
First Author: Chen NJ
Year: 2007
Journal: Nature
Title: C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a.
Volume: 446
Issue: 7132
Pages: 203-7
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Publication
30952817 | J:274640
First Author: Bisht K
Year: 2019
Journal: J Immunol
Title: Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway.
Volume: 202
Issue: 10
Pages: 2982-2990
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Publication
31597707 | J:281549
First Author: Mueller-Ortiz SL
Year: 2019
Journal: J Immunol
Title: The Second Receptor for C5a, C5aR2, Is Detrimental to Mice during Systemic Infection with Listeria monocytogenes.
Volume: 203
Issue: 10
Pages: 2701-2711
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Publication
34099640 | J:314516
First Author: Nording H
Year: 2021
Journal: Nat Commun
Title: The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets.
Volume: 12
Issue: 1
Pages: 3352
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Publication
35649359 | J:326469
First Author: Ding P
Year: 2022
Journal: Cell Rep
Title: Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Volume: 39
Issue: 9
Pages: 110851
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Publication
25355927 | J:283504
First Author: Engelke C
Year: 2014
Journal: J Immunol
Title: Distinct roles of the anaphylatoxins C3a and C5a in dendritic cell-mediated allergic asthma.
Volume: 193
Issue: 11
Pages: 5387-401
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Publication
32557852 | J:304196
First Author: Zheng QY
Year: 2020
Journal: FASEB J
Title: C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from γδ-T cells.
Volume: 34
Issue: 8
Pages: 10590-10604
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Publication
27382187 | J:319197
 
First Author: Haggadone MD
Year: 2016
Journal: Mediators Inflamm
Title: Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes.
Volume: 2016
Pages: 1340156
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Publication
28396344 | J:247648
First Author: Poppelaars F
Year: 2017
Journal: FASEB J
Title: Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury.
Volume: 31
Issue: 7
Pages: 3193-3204
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Publication
24771617 | J:211298
First Author: Nomaru H
Year: 2014
Journal: Glia
Title: Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia.
Volume: 62
Issue: 8
Pages: 1284-98
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Publication
30596651 | J:269520
First Author: Carroll JA
Year: 2018
Journal: PLoS One
Title: Toll-like receptor 2 confers partial neuroprotection during prion disease.
Volume: 13
Issue: 12
Pages: e0208559
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Publication
27543123 | J:267920
First Author: Kalbitz M
Year: 2016
Journal: FASEB J
Title: Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis.
Volume: 30
Issue: 12
Pages: 3997-4006
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Publication
32191644 | J:301750
 
First Author: Zhang T
Year: 2020
Journal: JCI Insight
Title: The C5a/C5aR2 axis promotes renal inflammation and tissue damage.
Volume: 5
Issue: 7
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Publication
29274925 | J:273883
 
First Author: Morgan M
Year: 2018
Journal: Mol Immunol
Title: Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain.
Volume: 94
Pages: 68-74
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Publication
30971430 | J:280420
First Author: Yu S
Year: 2019
Journal: J Biol Chem
Title: The complement receptor C5aR2 promotes protein kinase R expression and contributes to NLRP3 inflammasome activation and HMGB1 release from macrophages.
Volume: 294
Issue: 21
Pages: 8384-8394
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Publication
26727203 | J:249215
First Author: Khor KH
Year: 2016
Journal: PLoS One
Title: A Potential Link between the C5a Receptor 1 and the β1-Adrenoreceptor in the Mouse Heart.
Volume: 11
Issue: 1
Pages: e0146022
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Publication
36405694 | J:331830
 
First Author: Roewe J
Year: 2022
Journal: Front Immunol
Title: Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury.
Volume: 13
Pages: 980733
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Publication
28572445 | J:247773
First Author: Fattahi F
Year: 2017
Journal: FASEB J
Title: Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction.
Volume: 31
Issue: 9
Pages: 4129-4139
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Publication
31624141 | J:287848
First Author: Tan SM
Year: 2020
Journal: Diabetes
Title: Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.
Volume: 69
Issue: 1
Pages: 83-98
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Publication
28225753 | J:243863
First Author: Pandey MK
Year: 2017
Journal: Nature
Title: Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease.
Volume: 543
Issue: 7643
Pages: 108-112
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Publication
33495506 | J:300422
First Author: Chakraborty S
Year: 2021
Journal: Sci Rep
Title: Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock.
Volume: 11
Issue: 1
Pages: 2158
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Publication
29599777 | J:301858
 
First Author: Karsten CM
Year: 2018
Journal: Front Immunol
Title: Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2.
Volume: 9
Pages: 488
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Publication
29362231 | J:325846
 
First Author: Herrmann JB
Year: 2018
Journal: mBio
Title: Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment.
Volume: 9
Issue: 1
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Protein Coding Gene
MGP_CAROLIEiJ_G0029228 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031683 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021084 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030307 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1401897 | J:2871
First Author: Gerard C
Year: 1992
Journal: J Immunol
Title: Structural diversity in the extracellular faces of peptidergic G-protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor.
Volume: 149
Issue: 8
Pages: 2600-6
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Publication
16230349 | J:104097
First Author: Waters SM
Year: 2005
Journal: J Biol Chem
Title: Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.
Volume: 280
Issue: 49
Pages: 40617-23
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Publication
10903768 | J:120437
First Author: Tsuji RF
Year: 2000
Journal: J Immunol
Title: Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment.
Volume: 165
Issue: 3
Pages: 1588-98
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Publication
15845447 | J:97987
First Author: Hawlisch H
Year: 2005
Journal: Immunity
Title: C5a negatively regulates toll-like receptor 4-induced immune responses.
Volume: 22
Issue: 4
Pages: 415-26
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Publication
20132482 | J:160262
First Author: Ager RR
Year: 2010
Journal: J Neurochem
Title: Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.
Volume: 113
Issue: 2
Pages: 389-401
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Publication
21829669 | J:176526
First Author: Mullick A
Year: 2011
Journal: PLoS One
Title: A novel role for the fifth component of complement (C5) in cardiac physiology.
Volume: 6
Issue: 8
Pages: e22919
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Publication
11292607 | J:69304
First Author: Bhatia M
Year: 2001
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Complement factor C5a exerts an anti-inflammatory effect in acute pancreatitis and associated lung injury.
Volume: 280
Issue: 5
Pages: G974-8
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Publication
8779720 | J:69177
First Author: Höpken UE
Year: 1996
Journal: Nature
Title: The C5a chemoattractant receptor mediates mucosal defence to infection.
Volume: 383
Issue: 6595
Pages: 86-9
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Publication
10336122 | J:52135
First Author: Osaka H
Year: 1999
Journal: Neuroscience
Title: Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration.
Volume: 88
Issue: 4
Pages: 1073-82
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Publication
22137294 | J:318938
First Author: Liang DY
Year: 2012
Journal: Pain
Title: The complement component C5a receptor mediates pain and inflammation in a postsurgical pain model.
Volume: 153
Issue: 2
Pages: 366-372
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Publication
19864610 | J:157171
First Author: Peng Q
Year: 2009
Journal: J Immunol
Title: Dendritic cell function in allostimulation is modulated by C5aR signaling.
Volume: 183
Issue: 10
Pages: 6058-68
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Publication
23667486 | J:202133
First Author: Roy C
Year: 2013
Journal: PLoS One
Title: C5a receptor deficiency alters energy utilization and fat storage.
Volume: 8
Issue: 5
Pages: e62531
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Publication
18097053 | J:130912
First Author: Norman MU
Year: 2008
Journal: J Immunol
Title: Multichannel fluorescence spinning disk microscopy reveals early endogenous CD4 T cell recruitment in contact sensitivity via complement.
Volume: 180
Issue: 1
Pages: 510-21
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Publication
24607885 | J:212009
 
First Author: Li L
Year: 2014
Journal: Neurobiol Dis
Title: Complement C5a is detrimental to histological and functional locomotor recovery after spinal cord injury in mice.
Volume: 66
Pages: 74-82
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Publication
24786787 | J:212548
First Author: Vadrevu SK
Year: 2014
Journal: Cancer Res
Title: Complement c5a receptor facilitates cancer metastasis by altering T-cell responses in the metastatic niche.
Volume: 74
Issue: 13
Pages: 3454-65
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Publication
16511606 | J:106480
First Author: Köhl J
Year: 2006
Journal: J Clin Invest
Title: A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.
Volume: 116
Issue: 3
Pages: 783-96
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Publication
24935433 | J:230091
First Author: De Hoog VC
Year: 2014
Journal: Cardiovasc Res
Title: Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.
Volume: 103
Issue: 4
Pages: 521-9
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Publication
20651167 | J:185916
First Author: Li Q
Year: 2010
Journal: J Am Soc Nephrol
Title: Deficiency of C5aR prolongs renal allograft survival.
Volume: 21
Issue: 8
Pages: 1344-53
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Publication
11932923 | J:75976
First Author: Reiman R
Year: 2002
Journal: Eur J Immunol
Title: Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis.
Volume: 32
Issue: 4
Pages: 1157-63
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Publication
24043887 | J:206272
First Author: Phieler J
Year: 2013
Journal: J Immunol
Title: The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.
Volume: 191
Issue: 8
Pages: 4367-74
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