Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The entry includes Guanine nucleotide exchange factor C9orf72 protein, a component of the C9orf72-SMCR8 complex, which has guanine nucleotide exchange factor activity []and regulates autophagy [, ]. The C9orf72 protein is proposed to be a catalytic component for the exchange of GDP to GTP and promoting autophagosome maturation by converting inactive GDP-bound RAB8A and RAB39B into their active forms []. Defects in the C9orf72 gene are the cause of frontotemporal dementia and/or amyotrophic lateral sclerosis (FTDALS) which is an autosomal dominant neurodegenerative disorder. The disorder is caused by a large expansion of a GGGGCC hexanucleotide within the first C9orf72 intron located between the first and the second non-coding exons. The expansion leads to the loss of transcription of one of the two transcripts encoding isoform 1 and to the formation of nuclear RNA foci []. This family is found in eukaryotes.C9orf72 contains the DENN domain, which forms a heart-shaped structure (), with the N-terminal residues forming one lobe and the C-terminal residues forming the second one. The tripartite DENN (after differentially expressed in neoplastic versus normal cells) domain is found in several proteins that share common structural features and have been shown to be guanine nucleotide exchange factors (GEFs) for Rab GTPases, which are regulators of practically all membrane trafficking events in eukaryotes [, ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Sullivan PM |
Year: |
2016 |
Journal: |
Acta Neuropathol Commun |
Title: |
The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. |
Volume: |
4 |
Issue: |
1 |
Pages: |
51 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
481
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
317
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
DeJesus-Hernandez M |
Year: |
2011 |
Journal: |
Neuron |
Title: |
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. |
Volume: |
72 |
Issue: |
2 |
Pages: |
245-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sellier C |
Year: |
2016 |
Journal: |
EMBO J |
Title: |
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. |
Volume: |
35 |
Issue: |
12 |
Pages: |
1276-97 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
317
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang D |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. |
Volume: |
117 |
Issue: |
18 |
Pages: |
9876-9883 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nörpel J |
Year: |
2021 |
Journal: |
PLoS Biol |
Title: |
Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. |
Volume: |
19 |
Issue: |
7 |
Pages: |
e3001344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Atkinson RA |
Year: |
2015 |
Journal: |
Acta Neuropathol Commun |
Title: |
C9ORF72 expression and cellular localization over mouse development. |
Volume: |
3 |
|
Pages: |
59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung J |
Year: |
2017 |
Journal: |
Elife |
Title: |
Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sivadasan R |
Year: |
2016 |
Journal: |
Nat Neurosci |
Title: |
C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. |
Volume: |
19 |
Issue: |
12 |
Pages: |
1610-1618 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Rourke JG |
Year: |
2016 |
Journal: |
Science |
Title: |
C9orf72 is required for proper macrophage and microglial function in mice. |
Volume: |
351 |
Issue: |
6279 |
Pages: |
1324-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burberry A |
Year: |
2016 |
Journal: |
Sci Transl Med |
Title: |
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. |
Volume: |
8 |
Issue: |
347 |
Pages: |
347ra93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. |
Volume: |
108 |
Issue: |
46 |
Pages: |
18672-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koppers M |
Year: |
2015 |
Journal: |
Ann Neurol |
Title: |
C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits. |
Volume: |
78 |
Issue: |
3 |
Pages: |
426-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pang W |
Year: |
2023 |
Journal: |
iScience |
Title: |
C9ORF72 suppresses JAK-STAT mediated inflammation. |
Volume: |
26 |
Issue: |
5 |
Pages: |
106579 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hendricks E |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
The C9ORF72 repeat expansion alters neurodevelopment. |
Volume: |
42 |
Issue: |
8 |
Pages: |
112983 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ugolino J |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling. |
Volume: |
12 |
Issue: |
11 |
Pages: |
e1006443 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao S |
Year: |
2019 |
Journal: |
Acta Neuropathol Commun |
Title: |
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels. |
Volume: |
7 |
Issue: |
1 |
Pages: |
161 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferguson R |
Year: |
2016 |
Journal: |
J Anat |
Title: |
Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. |
Volume: |
229 |
Issue: |
6 |
Pages: |
871-891 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCauley ME |
Year: |
2020 |
Journal: |
Nature |
Title: |
C9orf72 in myeloid cells suppresses STING-induced inflammation. |
Volume: |
585 |
Issue: |
7823 |
Pages: |
96-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2016 |
Journal: |
Neuron |
Title: |
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD. |
Volume: |
90 |
Issue: |
3 |
Pages: |
521-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mordes DA |
Year: |
2020 |
Journal: |
Neuron |
Title: |
Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice. |
Volume: |
108 |
Issue: |
4 |
Pages: |
775-783.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khosravi B |
Year: |
2020 |
Journal: |
EMBO J |
Title: |
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD. |
Volume: |
39 |
Issue: |
8 |
Pages: |
e102811 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang T |
Year: |
2021 |
Journal: |
Cell Metab |
Title: |
C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly. |
Volume: |
33 |
Issue: |
3 |
Pages: |
531-546.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
He L |
Year: |
2023 |
Journal: |
Cell Death Differ |
Title: |
C9orf72 functions in the nucleus to regulate DNA damage repair. |
Volume: |
30 |
Issue: |
3 |
Pages: |
716-730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amalyan S |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Enhanced motor cortex output and disinhibition in asymptomatic female mice with C9orf72 genetic expansion. |
Volume: |
40 |
Issue: |
1 |
Pages: |
111043 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burberry A |
Year: |
2020 |
Journal: |
Nature |
Title: |
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria. |
Volume: |
582 |
Issue: |
7810 |
Pages: |
89-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Esanov R |
Year: |
2017 |
Journal: |
Mol Neurodegener |
Title: |
A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD. |
Volume: |
12 |
Issue: |
1 |
Pages: |
46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi Y |
Year: |
2018 |
Journal: |
Nat Med |
Title: |
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. |
Volume: |
24 |
Issue: |
3 |
Pages: |
313-325 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang J |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. |
Volume: |
90 |
Issue: |
3 |
Pages: |
535-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki N |
Year: |
2013 |
Journal: |
Nat Neurosci |
Title: |
The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD. |
Volume: |
16 |
Issue: |
12 |
Pages: |
1725-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Limone F |
Year: |
2024 |
Journal: |
Sci Transl Med |
Title: |
Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice. |
Volume: |
16 |
Issue: |
732 |
Pages: |
eadg7895 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2022 |
Journal: |
Mol Cell Neurosci |
Title: |
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice. |
Volume: |
121 |
|
Pages: |
103756 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lall D |
Year: |
2021 |
Journal: |
Neuron |
Title: |
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. |
Volume: |
109 |
Issue: |
14 |
Pages: |
2275-2291.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang YJ |
Year: |
2016 |
Journal: |
Nat Neurosci |
Title: |
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. |
Volume: |
19 |
Issue: |
5 |
Pages: |
668-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Langseth AJ |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog. |
Volume: |
7 |
Issue: |
1 |
Pages: |
5685 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maor-Nof M |
Year: |
2021 |
Journal: |
Cell |
Title: |
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). |
Volume: |
184 |
Issue: |
3 |
Pages: |
689-708.e20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bauer CS |
Year: |
2022 |
Journal: |
Acta Neuropathol |
Title: |
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. |
Volume: |
144 |
Issue: |
3 |
Pages: |
437-464 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chitiprolu M |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy. |
Volume: |
9 |
Issue: |
1 |
Pages: |
2794 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lagier-Tourenne C |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. |
Volume: |
110 |
Issue: |
47 |
Pages: |
E4530-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chew J |
Year: |
2015 |
Journal: |
Science |
Title: |
Neurodegeneration. C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits. |
Volume: |
348 |
Issue: |
6239 |
Pages: |
1151-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ho WY |
Year: |
2020 |
Journal: |
Acta Neuropathol Commun |
Title: |
Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zu T |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice. |
Volume: |
117 |
Issue: |
31 |
Pages: |
18591-18599 |
|
•
•
•
•
•
|
Publication |
First Author: |
Farg MA |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. |
Volume: |
23 |
Issue: |
13 |
Pages: |
3579-95 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
A C9orf72-CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress. |
Volume: |
32 |
Issue: |
21-22 |
Pages: |
1380-1397 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shao Q |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. |
Volume: |
16 |
Issue: |
9 |
Pages: |
1635-1650 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang M |
Year: |
2016 |
Journal: |
Sci Adv |
Title: |
A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. |
Volume: |
2 |
Issue: |
9 |
Pages: |
e1601167 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nelson AT |
Year: |
2024 |
Journal: |
EMBO Rep |
Title: |
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. |
Volume: |
25 |
Issue: |
5 |
Pages: |
2479-2510 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen L |
Year: |
2020 |
Journal: |
Neuron |
Title: |
Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs. |
Volume: |
108 |
Issue: |
4 |
Pages: |
784-796.e3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma L |
Year: |
2023 |
Journal: |
Hum Mol Genet |
Title: |
Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors. |
Volume: |
32 |
Issue: |
8 |
Pages: |
1252-1265 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang C |
Year: |
2019 |
Journal: |
Hum Mol Genet |
Title: |
Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. |
Volume: |
28 |
Issue: |
23 |
Pages: |
3940-3953 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laflamme C |
Year: |
2019 |
Journal: |
Elife |
Title: |
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki H |
Year: |
2019 |
Journal: |
Cell Death Dis |
Title: |
C9-ALS/FTD-linked proline-arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation. |
Volume: |
10 |
Issue: |
10 |
Pages: |
746 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ho WY |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. |
Volume: |
15 |
Issue: |
5 |
Pages: |
827-842 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi SY |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo. |
Volume: |
22 |
Issue: |
6 |
Pages: |
851-862 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panda SK |
Year: |
2013 |
Journal: |
Genetics |
Title: |
Highly efficient targeted mutagenesis in mice using TALENs. |
Volume: |
195 |
Issue: |
3 |
Pages: |
703-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lan Y |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. |
Volume: |
15 |
Issue: |
5 |
Pages: |
871-885 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis. |
Volume: |
32 |
Issue: |
13-14 |
Pages: |
929-943 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_09 |
|
Specimen Label: |
euxassay_010754_09 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_10 |
|
Specimen Label: |
euxassay_010754_10 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_11 |
|
Specimen Label: |
euxassay_010754_11 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_12 |
|
Specimen Label: |
euxassay_010754_12 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_13 |
|
Specimen Label: |
euxassay_010754_13 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_15 |
|
Specimen Label: |
euxassay_010754_15 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_16 |
|
Specimen Label: |
euxassay_010754_16 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_17 |
|
Specimen Label: |
euxassay_010754_17 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_18 |
|
Specimen Label: |
euxassay_010754_18 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416736 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4822699 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010754_19 |
|
Specimen Label: |
euxassay_010754_19 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692047 |
Age: |
postnatal adult |
Image: |
UC Davis_1861947 |
|
Specimen Label: |
UC Davis_1861947 |
Detected: |
true |
Specimen Num: |
32 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692047 |
Age: |
postnatal adult |
Image: |
UC Davis_1861948 |
|
Specimen Label: |
UC Davis_1861948 |
Detected: |
true |
Specimen Num: |
33 |
|
•
•
•
•
•
|