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Search results 1 to 100 out of 592 for Cacna1a

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Hits by Strain

Type Details Score
Gene
773 | CACNA1A
Type: gene
Organism: human
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Gene
100492135 | cacna1a
Type: gene
Organism: frog, western clawed
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Gene
key_34308 | CACNA1A
Type: gene
Organism: rabbit, European
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Gene
25398 | Cacna1a
Type: gene
Organism: rat
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Gene
455766 | CACNA1A
Type: gene
Organism: chimpanzee
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Gene
282648 | CACNA1A
Type: gene
Organism: cattle
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Gene
100686650 | CACNA1A
Type: gene
Organism: dog, domestic
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Gene
718291 | CACNA1A
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR005448 | CACNA1A
Type: Family
Description: Ca2+ ions are unique in that they not only carry charge but they are also the most widely used of diffusible second messengers. Voltage-dependent Ca2+ channels (VDCC) are a family of molecules that allow cells to couple electrical activity to intracellular Ca2+ signalling. The opening and closing of these channels by depolarizing stimuli, such as action potentials, allows Ca2+ ions to enter neurons down a steep electrochemical gradient, producing transient intracellular Ca2+ signals. Many of the processes that occur in neurons, including transmitter release, gene transcription and metabolism are controlled by Ca2+ influx occurring simultaneously at different cellular locales. The pore is formed by the alpha-1 subunit which incorporates the conduction pore, the voltage sensor and gating apparatus, and the known sites of channel regulation by second messengers, drugs, and toxins []. The activity of this pore is modulated by four tightly-coupled subunits: an intracellular beta subunit; a transmembrane gamma subunit; and a disulphide-linked complex of alpha-2 and delta subunits, which are proteolytically cleaved from the same gene product. Properties of the protein including gating voltage-dependence, G protein modulation and kinase susceptibility can be influenced by these subunits.Voltage-gated calcium channels are classified as T, L, N, P, Q and R, and are distinguished by their sensitivity to pharmacological blocks, single-channel conductance kinetics, and voltage-dependence. On the basis of their voltage activation properties, the voltage-gated calcium classes can be further divided into two broad groups: the low (T-type) and high (L, N, P, Q and R-type) threshold-activated channels.The alpha-1 subunit forms the pore for the import of extracellular calcium ions and, though regulated by the other subunits, is primarily responsible for the pharmacological properties of the channel []. It shares sequence characteristics with all voltage-dependent cation channels, and exploits the same 6-helix bundle structural motif - in both sodium and calcium channels, this motif is repeated 4 times within the sequence to give a 24-helix bundle. Within each of these repeats, 5 of the transmembrane (TM) segments (S1, S2, S3, S5, S6) are hydrophobic, while the other (S4) is positively charged and serves as the voltage-sensor. Several genes encoding alpha-1 subunits have been identified and can be divided into three functionally distinct families based on sequence homology - Cav1, Cav2 and Cav3 []. The Cav1 family forms channels mediating L-type calcium currents, the Cav2 family mediates P/Q-, N-, and R-type calcium currents, while the Cav3 family mediates T-type calcium currents.Several genes encoding alpha-1 subunits have been identified, each forming a distinct electrophysiological channel. P- and Q-type channels are formed from alpha-1A subunits and function in transmitter release []. P-type channels are prevalent in cerebellar Purkinje cells, but are also expressed in many central and peripheral neurons, such as the spinal cord and visual cortex. By contrast, Q-type channels are found in cerebellar granule neurones and the hippocampus. Different mutations in the alpha-1A subunit can produce the following human diseases: episodic ataxia type-2familial hemiplegic migrainespinocerebellar ataxia type-6All 3 diseases result in cerebellar atrophy, but they differ in the extent and rate of progression of neuronal degeneration.
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Protein Coding Gene
MGI:109482 | Cacna1a
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7736180
Assay Type: RNA in situ
Annotation Date: 2024-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7736192
Age: postnatal day 4
Image: 4B Cacna1a
Specimen Label: 4B Cacna1a
Detected: true
Specimen Num: 1
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Publication
17146767 | J:117062
First Author: Todorov B
Year: 2006
Journal: Genesis
Title: Conditional inactivation of the Cacna1a gene in transgenic mice.
Volume: 44
Issue: 12
Pages: 589-94
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Publication
22952933 | J:191648
First Author: Li W
Year: 2012
Journal: PLoS One
Title: New ataxic tottering-6j mouse allele containing a Cacna1a gene mutation.
Volume: 7
Issue: 8
Pages: e44230
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Publication
15003170 | J:88693
First Author: van den Maagdenberg AM
Year: 2004
Journal: Neuron
Title: A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression.
Volume: 41
Issue: 5
Pages: 701-10
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Publication
23827678 | J:199996
First Author: Du X
Year: 2013
Journal: Cell
Title: Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6.
Volume: 154
Issue: 1
Pages: 118-33
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Publication
30649209 | J:294560
First Author: Loonen ICM
Year: 2019
Journal: Brain
Title: Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice.
Volume: 142
Issue: 2
Pages: 412-425
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Publication
21411672 | J:170451
First Author: Mark MD
Year: 2011
Journal: J Neurosci
Title: Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations.
Volume: 31
Issue: 11
Pages: 4311-26
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Publication
24583041 | J:210330
 
First Author: Hullugundi SK
Year: 2014
Journal: Neuroscience
Title: A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1.
Volume: 266
Pages: 244-54
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Publication
11344116 | J:76459
First Author: Fletcher CF
Year: 2001
Journal: FASEB J
Title: Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity.
Volume: 15
Issue: 7
Pages: 1288-90
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Publication
19854154 | J:155607
First Author: Saito H
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice.
Volume: 390
Issue: 3
Pages: 1029-33
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Publication
31800012 | J:293639
First Author: Miao QL
Year: 2020
Journal: Brain
Title: Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.
Volume: 143
Issue: 1
Pages: 161-174
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Publication
22005682 | J:191542
First Author: Fioretti B
Year: 2011
Journal: J Physiol
Title: Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine.
Volume: 589
Issue: Pt 23
Pages: 5879-95
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189894
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cacna1a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189894
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cacna1a
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189894
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cacna1a
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189894
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cacna1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189894
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cacna1a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189894
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cacna1a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6168865
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189894
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cacna1a
Detected: true
Specimen Num: 7
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Protein
P97445
Organism: Mus musculus/domesticus
Length: 2368  
Fragment?: false
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Protein
Q3UHA5
Organism: Mus musculus/domesticus
Length: 2321  
Fragment?: false
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Protein
Q3UHN4
Organism: Mus musculus/domesticus
Length: 2368  
Fragment?: false
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Protein
Q8R5M7
Organism: Mus musculus/domesticus
Length: 2327  
Fragment?: false
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Protein
E9Q1R5
Organism: Mus musculus/domesticus
Length: 2321  
Fragment?: false
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Protein
A0A1L1SQZ2
Organism: Mus musculus/domesticus
Length: 2321  
Fragment?: true
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Protein
Q8R5M6
Organism: Mus musculus/domesticus
Length: 2365  
Fragment?: false
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Protein
A0A571BET0
Organism: Mus musculus/domesticus
Length: 2457  
Fragment?: false
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Publication
14657414 | -
First Author: Catterall WA
Year: 2003
Journal: Pharmacol Rev
Title: International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels.
Volume: 55
Issue: 4
Pages: 579-81
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Publication
11031246 | -
 
First Author: Catterall WA
Year: 2000
Journal: Annu Rev Cell Dev Biol
Title: Structure and regulation of voltage-gated Ca2+ channels.
Volume: 16
Pages: 521-55
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Publication
10774722 | J:61466
First Author: Ertel EA
Year: 2000
Journal: Neuron
Title: Nomenclature of voltage-gated calcium channels.
Volume: 25
Issue: 3
Pages: 533-5
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Publication
8825650 | -
First Author: Diriong S
Year: 1995
Journal: Genomics
Title: Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.
Volume: 30
Issue: 3
Pages: 605-9
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Publication
16111830 | J:104354
First Author: Kaja S
Year: 2005
Journal: Neuroscience
Title: Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness.
Volume: 135
Issue: 1
Pages: 81-95
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Publication
23516282 | J:196594
First Author: Maejima T
Year: 2013
Journal: J Neurosci
Title: Postnatal loss of P/Q-type channels confined to rhombic-lip-derived neurons alters synaptic transmission at the parallel fiber to purkinje cell synapse and replicates genomic Cacna1a mutation phenotype of ataxia and seizures in mice.
Volume: 33
Issue: 12
Pages: 5162-74
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Allele
Cacna1a<tm3.1(CACNA1A)Ttan> | MGI:6474215
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 3.1, Tsutomu Tanabe
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
31628185 | J:282371
First Author: Jansen NA
Year: 2019
Journal: J Neurosci
Title: Apnea Associated with Brainstem Seizures in Cacna1a S218L Mice Is Caused by Medullary Spreading Depolarization.
Volume: 39
Issue: 48
Pages: 9633-9644
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Publication
- | J:198844
     
First Author: Harris BS
Year: 2013
Journal: MGI Direct Data Submission
Title: Small roller: A new recessive neurological mutation that maps to Chromosome 8
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Publication
- | J:267668
     
First Author: Keef J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for totter.
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Publication
19484318 | J:164112
First Author: Plomp JJ
Year: 2009
Journal: Cerebellum
Title: The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings.
Volume: 8
Issue: 3
Pages: 222-30
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Publication
16242631 | J:102801
First Author: Fureman BE
Year: 2005
Journal: Neurobiol Dis
Title: Noradrenergic blockade prevents attacks in a model of episodic dysfunction caused by a channelopathy.
Volume: 20
Issue: 2
Pages: 227-32
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Publication
18687887 | J:139488
First Author: Watase K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels.
Volume: 105
Issue: 33
Pages: 11987-92
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Publication
30922876 | J:276254
First Author: Du X
Year: 2019
Journal: Neuron
Title: α1ACT Is Essential for Survival and Early Cerebellar Programming in a Critical Neonatal Window.
Volume: 102
Issue: 4
Pages: 770-785.e7
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Publication
24768804 | J:214010
 
First Author: Salvi J
Year: 2014
Journal: Neurobiol Dis
Title: RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2.
Volume: 68
Pages: 47-56
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Publication
25855180 | J:221681
First Author: Cramer SW
Year: 2015
Journal: J Neurosci
Title: Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Volume: 35
Issue: 14
Pages: 5664-79
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Publication
18093175 | J:132196
First Author: Ovsepian SV
Year: 2008
Journal: Eur J Neurosci
Title: The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts.
Volume: 27
Issue: 1
Pages: 93-103
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Publication
17513018 | J:140908
First Author: Alonso I
Year: 2008
Journal: Neurobiol Aging
Title: Motor and cognitive deficits in the heterozygous leaner mouse, a Cav2.1 voltage-gated Ca2+ channel mutant.
Volume: 29
Issue: 11
Pages: 1733-43
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Publication
19850086 | J:156904
First Author: Takahashi E
Year: 2010
Journal: Behav Brain Res
Title: Neonatal motor functions in Cacna1a-mutant rolling Nagoya mice.
Volume: 207
Issue: 2
Pages: 273-9
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Publication
19104150 | J:144701
First Author: Eikermann-Haerter K
Year: 2009
Journal: J Clin Invest
Title: Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1.
Volume: 119
Issue: 1
Pages: 99-109
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Publication
21870131 | J:234599
First Author: Todorov B
Year: 2012
Journal: Cerebellum
Title: Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice.
Volume: 11
Issue: 1
Pages: 246-58
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Publication
25109669 | J:217557
 
First Author: Rose SJ
Year: 2014
Journal: Exp Neurol
Title: The first knockin mouse model of episodic ataxia type 2.
Volume: 261
Pages: 553-62
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Publication
11160387 | J:71860
First Author: Zwingman TA
Year: 2001
Journal: J Neurosci
Title: Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a.
Volume: 21
Issue: 4
Pages: 1169-78
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Publication
26208839 | J:226272
 
First Author: Kaja S
Year: 2015
Journal: Neuroscience
Title: Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels.
Volume: 304
Pages: 198-208
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Publication
25716839 | J:219849
First Author: Dilekoz E
Year: 2015
Journal: J Neurosci
Title: Migraine mutations impair hippocampal learning despite enhanced long-term potentiation.
Volume: 35
Issue: 8
Pages: 3397-402
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Publication
35238776 | J:321889
   
First Author: Terpollili NA
Year: 2022
Journal: Elife
Title: CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury.
Volume: 11
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Publication
20186955 | J:211767
First Author: van den Maagdenberg AM
Year: 2010
Journal: Ann Neurol
Title: High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice.
Volume: 67
Issue: 1
Pages: 85-98
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Publication
26887908 | J:278031
First Author: Kim TY
Year: 2016
Journal: Exp Anim
Title: Protein expression pattern in cerebellum of Cav2.1 mutant, tottering-6j mice.
Volume: 65
Issue: 3
Pages: 207-14
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Publication
36078147 | J:329002
 
First Author: Chang HHV
Year: 2022
Journal: Cells
Title: Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6).
Volume: 11
Issue: 17
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Publication
23115190 | J:192290
First Author: Gao Z
Year: 2012
Journal: J Neurosci
Title: Cerebellar ataxia by enhanced Ca(V)2.1 currents is alleviated by Ca2+-dependent K+-channel activators in Cacna1a(S218L) mutant mice.
Volume: 32
Issue: 44
Pages: 15533-46
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Publication
17161543 | J:121290
First Author: Kaja S
Year: 2007
Journal: Neuroscience
Title: Characterization of acetylcholine release and the compensatory contribution of non-Ca(v)2.1 channels at motor nerve terminals of leaner Ca(v)2.1-mutant mice.
Volume: 144
Issue: 4
Pages: 1278-87
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Publication
17439489 | J:125038
First Author: Kaja S
Year: 2007
Journal: Eur J Neurosci
Title: Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya.
Volume: 25
Issue: 7
Pages: 2009-20
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Publication
34077522 | J:322324
First Author: Bohne P
Year: 2021
Journal: Hum Mol Genet
Title: Cognitive deficits in episodic ataxia type 2 mouse models.
Volume: 30
Issue: 19
Pages: 1811-1832
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Publication
14724264 | J:194956
First Author: Stahl JS
Year: 2004
Journal: J Neurophysiol
Title: Eye movements of the murine P/Q calcium channel mutant rocker, and the impact of aging.
Volume: 91
Issue: 5
Pages: 2066-78
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Publication
21490217 | J:170969
First Author: Eikermann-Haerter K
Year: 2011
Journal: J Neurosci
Title: Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice.
Volume: 31
Issue: 15
Pages: 5755-63
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Publication
22956801 | J:333615
First Author: Inchauspe CG
Year: 2012
Journal: J Neurophysiol
Title: Presynaptic CaV2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held.
Volume: 108
Issue: 11
Pages: 2967-76
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Publication
24849341 | J:211350
First Author: Di Guilmi MN
Year: 2014
Journal: J Neurosci
Title: Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i.
Volume: 34
Issue: 21
Pages: 7047-58
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Publication
31337678 | J:277450
First Author: Miyoshi C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice.
Volume: 116
Issue: 32
Pages: 16062-16067
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Publication
17188510 | J:123243
First Author: Saegusa H
Year: 2007
Journal: Mol Cell Neurosci
Title: Properties of human Cav2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells.
Volume: 34
Issue: 2
Pages: 261-70
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Publication
17982453 | J:130784
First Author: Glasscock E
Year: 2007
Journal: Nat Neurosci
Title: Masking epilepsy by combining two epilepsy genes.
Volume: 10
Issue: 12
Pages: 1554-8
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Publication
23451282 | J:199328
First Author: Stahl JS
Year: 2013
Journal: PLoS One
Title: 4-aminopyridine does not enhance flocculus function in tottering, a mouse model of vestibulocerebellar dysfunction and ataxia.
Volume: 8
Issue: 2
Pages: e57895
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Publication
25481823 | J:237437
 
First Author: Inchauspe CG
Year: 2015
Journal: Hear Res
Title: Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice.
Volume: 319
Pages: 56-68
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Publication
24355314 | J:211481
 
First Author: Park J
Year: 2014
Journal: Neurobiol Dis
Title: Differential trigeminovascular nociceptive responses in the thalamus in the familial hemiplegic migraine 1 knock-in mouse: a Fos protein study.
Volume: 64
Pages: 1-7
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Publication
26758833 | J:228867
First Author: Bomben VC
Year: 2016
Journal: J Neurosci
Title: Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy.
Volume: 36
Issue: 2
Pages: 405-18
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Publication
11756409 | J:75166
First Author: Tsunemi T
Year: 2002
Journal: J Biol Chem
Title: Novel Cav2.1 splice variants isolated from Purkinje cells do not generate P-type Ca2+ current.
Volume: 277
Issue: 9
Pages: 7214-21
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Publication
16381801 | J:135773
First Author: Kaja S
Year: 2006
Journal: J Neurophysiol
Title: Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.
Volume: 95
Issue: 4
Pages: 2698-704
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Publication
17376154 | J:119639
First Author: Xie G
Year: 2007
Journal: Genes Brain Behav
Title: Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A.
Volume: 6
Issue: 8
Pages: 717-27
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Publication
18597946 | J:137816
First Author: Miki T
Year: 2008
Journal: Neuroscience
Title: Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.
Volume: 155
Issue: 1
Pages: 31-44
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Publication
23426690 | J:195984
First Author: Koch H
Year: 2013
Journal: J Neurosci
Title: Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.
Volume: 33
Issue: 8
Pages: 3633-45
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Publication
23577145 | J:200145
First Author: Hullugundi SK
Year: 2013
Journal: PLoS One
Title: The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1).
Volume: 8
Issue: 4
Pages: e60677
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Publication
24758835 | J:303241
First Author: Yoshimoto T
Year: 2014
Journal: J Vet Med Sci
Title: Rolling Nagoya mouse strain (PROD-rol/rol) with classic piebald mutation.
Volume: 76
Issue: 8
Pages: 1093-8
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Publication
24205277 | J:209226
First Author: Mallmann RT
Year: 2013
Journal: PLoS One
Title: Ablation of Ca(V)2.1 voltage-gated Ca²⁺ channels in mouse forebrain generates multiple cognitive impairments.
Volume: 8
Issue: 10
Pages: e78598
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Publication
36682446 | J:352914
 
First Author: Singh M
Year: 2023
Journal: Neuroscience
Title: Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2.1 Channels.
Volume: 513
Pages: 38-53
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Publication
33305180 | J:306911
First Author: Yamashiro K
Year: 2020
Journal: iScience
Title: AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.
Volume: 23
Issue: 12
Pages: 101820
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Publication
- | J:338850
     
First Author: Meyer KJ
Year: 2023
Journal: MGI Direct Data Submission
Title: Direct Data Submission of Multiple Allele.
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Publication
23595603 | J:317577
First Author: Rossignol E
Year: 2013
Journal: Ann Neurol
Title: CaV 2.1 ablation in cortical interneurons selectively impairs fast-spiking basket cells and causes generalized seizures.
Volume: 74
Issue: 2
Pages: 209-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0031301 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033863 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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