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Search results 1 to 100 out of 113 for Calhm1

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Hits by Category

Hits by Strain

Type Details Score
Gene
255022 | CALHM1
Type: gene
Organism: human
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Gene
101734555 | calhm1
Type: gene
Organism: frog, western clawed
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Gene
499367 | Calhm1
Type: gene
Organism: rat
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Gene
466194 | CALHM1
Type: gene
Organism: chimpanzee
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Gene
532026 | CALHM1
Type: gene
Organism: cattle
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Gene
100855454 | CALHM1
Type: gene
Organism: dog, domestic
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Gene
428977 | CALHM1
Type: gene
Organism: chicken
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Gene
714766 | CALHM1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3643383 | Calhm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029568 | CALHM1
Type: Family
Description: Calcium homeostasis modulator protein 1 (CALHM1) is a Ca(2+) channel controlling neuronal excitability [, ]. In humans, it controls the Ca2+ dependent MEK, ERK, RSK and MSK signalling cascade in neurons []. It may be involved in the pathogenesis of Alzheimer's disease (AD) [].
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Publication
23345406 | J:200461
First Author: Dreses-Werringloer U
Year: 2013
Journal: J Cell Sci
Title: CALHM1 controls the Ca²⁺-dependent MEK, ERK, RSK and MSK signaling cascade in neurons.
Volume: 126
Issue: Pt 5
Pages: 1199-206
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Publication
24846212 | J:278276
First Author: Tordoff MG
Year: 2014
Journal: Chem Senses
Title: Salty taste deficits in CALHM1 knockout mice.
Volume: 39
Issue: 6
Pages: 515-28
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Publication
28734079 | J:333223
First Author: Taruno A
Year: 2017
Journal: J Physiol
Title: Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel.
Volume: 595
Issue: 18
Pages: 6121-6145
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Publication
22723178 | J:244828
First Author: Wu J
Year: 2012
Journal: Protein Cell
Title: Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression.
Volume: 3
Issue: 6
Pages: 470-80
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Publication
27066908 | J:251041
 
First Author: Vingtdeux V
Year: 2016
Journal: Sci Rep
Title: CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.
Volume: 6
Pages: 24250
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Publication
23467090 | J:194915
First Author: Taruno A
Year: 2013
Journal: Nature
Title: CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.
Volume: 495
Issue: 7440
Pages: 223-6
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Publication
25855639 | J:278275
First Author: Hellekant G
Year: 2015
Journal: Chem Senses
Title: CALHM1 Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span.
Volume: 40
Issue: 6
Pages: 373-9
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Publication
24384370 | J:312209
 
First Author: Sclafani A
Year: 2014
Journal: Physiol Behav
Title: Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice.
Volume: 126
Pages: 25-9
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Publication
29768036 | J:264580
First Author: Sclafani A
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Greater reductions in fat preferences in CALHM1 than CD36 knockout mice.
Volume: 315
Issue: 3
Pages: R576-R585
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Publication
34998826 | J:332955
 
First Author: Sclafani A
Year: 2022
Journal: Physiol Behav
Title: Fat preference deficits and experience-induced recovery in global taste-deficient Trpm5 and Calhm1 knockout mice.
Volume: 246
Pages: 113695
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Publication
29739879 | J:273601
 
First Author: Romanov RA
Year: 2018
Journal: Sci Signal
Title: Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex.
Volume: 11
Issue: 529
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Publication
25999473 | J:232905
First Author: Vingtdeux V
Year: 2015
Journal: J Cell Sci
Title: CALHM1 ion channel elicits amyloid-β clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain.
Volume: 128
Issue: 13
Pages: 2330-8
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Publication
23884934 | -
First Author: Tanis JE
Year: 2013
Journal: J Neurosci
Title: CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans.
Volume: 33
Issue: 30
Pages: 12275-86
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Protein
D3Z291
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
A0A1Y1C8H8
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
24069280 | -
First Author: Rubio-Moscardo F
Year: 2013
Journal: PLoS One
Title: Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.
Volume: 8
Issue: 9
Pages: e74203
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Publication
22711817 | J:186424
First Author: Ma Z
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability.
Volume: 109
Issue: 28
Pages: E1963-71
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Publication
28202574 | J:293040
First Author: Ma Z
Year: 2017
Journal: J Neurophysiol
Title: Action potentials and ion conductances in wild-type and CALHM1-knockout type II taste cells.
Volume: 117
Issue: 5
Pages: 1865-1876
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Publication
30804437 | J:286883
First Author: Kashio M
Year: 2019
Journal: Sci Rep
Title: CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells.
Volume: 9
Issue: 1
Pages: 2681
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Publication
33788965 | J:347143
First Author: Okui M
Year: 2021
Journal: FASEB J
Title: Posttranslational regulation of CALHM1/3 channel: N-linked glycosylation and S-palmitoylation.
Volume: 35
Issue: 5
Pages: e21527
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Publication
29681531 | J:269649
First Author: Ma Z
Year: 2018
Journal: Neuron
Title: CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.
Volume: 98
Issue: 3
Pages: 547-561.e10
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Publication
28751666 | J:253717
First Author: Workman AD
Year: 2017
Journal: Sci Rep
Title: CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells.
Volume: 7
Issue: 1
Pages: 6687
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Publication
32229307 | J:298578
First Author: Nomura K
Year: 2020
Journal: Neuron
Title: All-Electrical Ca2+-Independent Signal Transduction Mediates Attractive Sodium Taste in Taste Buds.
Volume: 106
Issue: 5
Pages: 816-829.e6
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Publication
24912134 | J:244371
 
First Author: Tordoff MG
Year: 2014
Journal: Physiol Behav
Title: Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains.
Volume: 135
Pages: 49-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0023052 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025225 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3643383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025639 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024421 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025068 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014542 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023973 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6121432
Age: embryonic day 14.0
Specimen Label: E14 RT+
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6121432
Age: embryonic day 16.0
Specimen Label: E16 RT+
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6121432
Age: embryonic day 18.0
Specimen Label: E18 RT+
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6121432
Age: postnatal day 0
Specimen Label: P0 RT+
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal day 7
Specimen Label: P7 RT+
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 2
Specimen Label: 2w RT+
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 4
Specimen Label: 4w RT+
Detected: false
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 8
Specimen Label: 8w RT+
Detected: false
Specimen Num: 15
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 4
Specimen Label: 4m RT+
Detected: false
Specimen Num: 17
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 8
Specimen Label: 8m RT+
Detected: false
Specimen Num: 19
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GXD Expression
GXD Expression
     
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 12
Specimen Label: 12m RT+
Detected: false
Specimen Num: 21
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GXD Expression
GXD Expression
     
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) +/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) V5-ires-Cre/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) V5-ires-Cre/+
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4830302
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7435058
Age: postnatal week 10-20
Note: Expression is limited to sweet-, bitter-, and umami-sensing taste cells; it is not expressed in other taste cells.
Specimen Label: 5D upper
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883445
Note: vas deferens
Specimen Label: UC Davis_1883445
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4830302
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7435058
Age: postnatal week 10-20
Note: Expression is limited to sweet-, bitter-, and umami-sensing taste cells; it is not expressed in other taste cells.
Specimen Label: 5D upper
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883441
Specimen Label: UC Davis_1883441
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883439
Specimen Label: UC Davis_1883439
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883443
Specimen Label: UC Davis_1883443
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883444
Specimen Label: UC Davis_1883444
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883440
Specimen Label: UC Davis_1883440
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 7
Specimen Label: P7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 14
Specimen Label: P14
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 30
Specimen Label: P30
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal month 2
Specimen Label: Pm2
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal month 6
Specimen Label: Pm6
Detected: false
Specimen Num: 5
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Publication
28148491 | J:250376
First Author: Glendinning JI
Year: 2017
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Glucose elicits cephalic-phase insulin release in mice by activating KATP channels in taste cells.
Volume: 312
Issue: 4
Pages: R597-R610
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Publication
37045597 | J:335201
 
First Author: Ohmoto M
Year: 2023
Journal: eNeuro
Title: A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells.
Volume: 10
Issue: 4
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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