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Search results 1 to 100 out of 112 for Calhm1

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0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Calcium homeostasis modulator protein 1 (CALHM1) is a Ca(2+) channel controlling neuronal excitability [, ]. In humans, it controls the Ca2+ dependent MEK, ERK, RSK and MSK signalling cascade in neurons []. It may be involved in the pathogenesis of Alzheimer's disease (AD) [].
Publication
First Author: Dreses-Werringloer U
Year: 2013
Journal: J Cell Sci
Title: CALHM1 controls the Ca²⁺-dependent MEK, ERK, RSK and MSK signaling cascade in neurons.
Volume: 126
Issue: Pt 5
Pages: 1199-206
Publication
First Author: Tordoff MG
Year: 2014
Journal: Chem Senses
Title: Salty taste deficits in CALHM1 knockout mice.
Volume: 39
Issue: 6
Pages: 515-28
Publication
First Author: Taruno A
Year: 2017
Journal: J Physiol
Title: Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel.
Volume: 595
Issue: 18
Pages: 6121-6145
Publication
First Author: Wu J
Year: 2012
Journal: Protein Cell
Title: Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression.
Volume: 3
Issue: 6
Pages: 470-80
Publication
First Author: Taruno A
Year: 2013
Journal: Nature
Title: CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.
Volume: 495
Issue: 7440
Pages: 223-6
Publication  
First Author: Vingtdeux V
Year: 2016
Journal: Sci Rep
Title: CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.
Volume: 6
Pages: 24250
Publication
First Author: Hellekant G
Year: 2015
Journal: Chem Senses
Title: CALHM1 Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span.
Volume: 40
Issue: 6
Pages: 373-9
Publication  
First Author: Sclafani A
Year: 2014
Journal: Physiol Behav
Title: Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice.
Volume: 126
Pages: 25-9
Publication
First Author: Sclafani A
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Greater reductions in fat preferences in CALHM1 than CD36 knockout mice.
Volume: 315
Issue: 3
Pages: R576-R585
Publication  
First Author: Romanov RA
Year: 2018
Journal: Sci Signal
Title: Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex.
Volume: 11
Issue: 529
Publication  
First Author: Sclafani A
Year: 2022
Journal: Physiol Behav
Title: Fat preference deficits and experience-induced recovery in global taste-deficient Trpm5 and Calhm1 knockout mice.
Volume: 246
Pages: 113695
Publication
First Author: Vingtdeux V
Year: 2015
Journal: J Cell Sci
Title: CALHM1 ion channel elicits amyloid-β clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain.
Volume: 128
Issue: 13
Pages: 2330-8
Publication
First Author: Tanis JE
Year: 2013
Journal: J Neurosci
Title: CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans.
Volume: 33
Issue: 30
Pages: 12275-86
Protein
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
Publication
First Author: Rubio-Moscardo F
Year: 2013
Journal: PLoS One
Title: Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.
Volume: 8
Issue: 9
Pages: e74203
Publication
First Author: Ma Z
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability.
Volume: 109
Issue: 28
Pages: E1963-71
Publication
First Author: Ma Z
Year: 2017
Journal: J Neurophysiol
Title: Action potentials and ion conductances in wild-type and CALHM1-knockout type II taste cells.
Volume: 117
Issue: 5
Pages: 1865-1876
Publication
First Author: Kashio M
Year: 2019
Journal: Sci Rep
Title: CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells.
Volume: 9
Issue: 1
Pages: 2681
Publication
First Author: Ma Z
Year: 2018
Journal: Neuron
Title: CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.
Volume: 98
Issue: 3
Pages: 547-561.e10
Publication
First Author: Workman AD
Year: 2017
Journal: Sci Rep
Title: CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells.
Volume: 7
Issue: 1
Pages: 6687
Publication  
First Author: Tordoff MG
Year: 2014
Journal: Physiol Behav
Title: Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains.
Volume: 135
Pages: 49-54
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6121432
Age: embryonic day 14.0
Specimen Label: E14 RT+
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6121432
Age: embryonic day 16.0
Specimen Label: E16 RT+
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6121432
Age: embryonic day 18.0
Specimen Label: E18 RT+
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6121432
Age: postnatal day 0
Specimen Label: P0 RT+
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal day 7
Specimen Label: P7 RT+
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 2
Specimen Label: 2w RT+
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 4
Specimen Label: 4w RT+
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal week 8
Specimen Label: 8w RT+
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 4
Specimen Label: 4m RT+
Detected: false
Specimen Num: 17
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 8
Specimen Label: 8m RT+
Detected: false
Specimen Num: 19
GXD Expression      
Probe: MGI:6121396
Assay Type: RT-PCR
Annotation Date: 2018-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121432
Age: postnatal month 12
Specimen Label: 12m RT+
Detected: false
Specimen Num: 21
GXD Expression      
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) V5-ires-Cre/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7435177
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Stage: TS28
Assay Id: MGI:7435190
Age: postnatal week 10-20
Specimen Label: RT(+) V5-ires-Cre/+
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4830302
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7435058
Age: postnatal week 10-20
Note: Expression is limited to sweet-, bitter-, and umami-sensing taste cells; it is not expressed in other taste cells.
Specimen Label: 5D upper
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883445
Note: vas deferens
Specimen Label: UC Davis_1883445
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4830302
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7435058
Age: postnatal week 10-20
Note: Expression is limited to sweet-, bitter-, and umami-sensing taste cells; it is not expressed in other taste cells.
Specimen Label: 5D upper
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883441
Specimen Label: UC Davis_1883441
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883439
Specimen Label: UC Davis_1883439
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883443
Specimen Label: UC Davis_1883443
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883444
Specimen Label: UC Davis_1883444
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692940
Age: postnatal adult
Image: UC Davis_1883440
Specimen Label: UC Davis_1883440
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 7
Specimen Label: P7
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 14
Specimen Label: P14
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal day 30
Specimen Label: P30
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal month 2
Specimen Label: Pm2
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6121410
Assay Type: RNA in situ
Annotation Date: 2018-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6121411
Age: postnatal month 6
Specimen Label: Pm6
Detected: false
Specimen Num: 5
Publication
First Author: Glendinning JI
Year: 2017
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Glucose elicits cephalic-phase insulin release in mice by activating KATP channels in taste cells.
Volume: 312
Issue: 4
Pages: R597-R610
Publication  
First Author: Ohmoto M
Year: 2023
Journal: eNeuro
Title: A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells.
Volume: 10
Issue: 4
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.