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Search results 1 to 100 out of 332 for Cap1

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0.042s
Type Details Score
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: human
Protein Domain
Type: Family
Description: This entry represents the adenylyl cyclase-associated protein 1 (also known as CAP1) from vertebrates. It belongs to the CAP family, which is conserved from yeasts to humans. Budding yeast CAP, also known as Srv2, is a multifunctional protein that plays roles in Ras signalling and in actin organisation. Although the Ras signalling function does not extend beyond yeasts, the actin regulation function is conserved in all eukaryotes []. In mammals, CAP1 regulates the actin cytoskeleton, cofilin function, and cell adhesion [].
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Wang C
Year: 2008
Journal: J Cell Sci
Title: Mitochondrial shuttling of CAP1 promotes actin- and cofilin-dependent apoptosis.
Volume: 121
Issue: Pt 17
Pages: 2913-20
Publication
First Author: Zhang H
Year: 2013
Journal: J Biol Chem
Title: Mammalian adenylyl cyclase-associated protein 1 (CAP1) regulates cofilin function, the actin cytoskeleton, and cell adhesion.
Volume: 288
Issue: 29
Pages: 20966-77
Publication
First Author: Zhou GL
Year: 2014
Journal: J Cell Sci
Title: Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin.
Volume: 127
Issue: Pt 23
Pages: 5052-65
Publication  
First Author: Schneider F
Year: 2021
Journal: Cells
Title: Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons.
Volume: 10
Issue: 6
Protein
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Gene
Type: gene
Organism: cattle
Publication
First Author: Makkonen M
Year: 2013
Journal: J Biol Chem
Title: Mammalian and malaria parasite cyclase-associated proteins catalyze nucleotide exchange on G-actin through a conserved mechanism.
Volume: 288
Issue: 2
Pages: 984-94
Publication
First Author: Jansen S
Year: 2014
Journal: J Biol Chem
Title: Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics.
Volume: 289
Issue: 44
Pages: 30732-42
Publication
First Author: Lee S
Year: 2014
Journal: Cell Metab
Title: Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.
Volume: 19
Issue: 3
Pages: 484-97
Publication
First Author: Peche V
Year: 2007
Journal: Cell Mol Life Sci
Title: CAP2, cyclase-associated protein 2, is a dual compartment protein.
Volume: 64
Issue: 19-20
Pages: 2702-15
Publication  
First Author: Jin ZL
Year: 2018
Journal: J Cell Sci
Title: CAP1-mediated actin cycling via ADF/cofilin proteins is essential for asymmetric division in mouse oocytes.
Volume: 131
Issue: 23
Publication
First Author: Bertling E
Year: 2004
Journal: Mol Biol Cell
Title: Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells.
Volume: 15
Issue: 5
Pages: 2324-34
Publication  
First Author: Schneider F
Year: 2021
Journal: Prog Neurobiol
Title: Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function.
Volume: 202
Pages: 102050
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Vojtek AB
Year: 1993
Journal: J Cell Sci
Title: Identification and characterization of a cDNA encoding mouse CAP: a homolog of the yeast adenylyl cyclase associated protein.
Volume: 105 ( Pt 3)
Pages: 777-85
Publication
First Author: Hubberstey AV
Year: 2002
Journal: FASEB J
Title: Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization.
Volume: 16
Issue: 6
Pages: 487-99
Publication
First Author: Benlali A
Year: 2000
Journal: Cell
Title: act up controls actin polymerization to alter cell shape and restrict Hedgehog signaling in the Drosophila eye disc.
Volume: 101
Issue: 3
Pages: 271-81
Publication
First Author: Nakamura J
Year: 1997
Journal: Biochim Biophys Acta
Title: Glutathione alters the mode of calcium-mediated regulation of adenylyl cyclase in membranes from mouse brain.
Volume: 1339
Issue: 2
Pages: 239-46
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:7442992
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:7442992
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7442992
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7442992
Age: embryonic day 18.5
Image: 1
Specimen Label: E18.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7442992
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7442993
Age: postnatal day 0
Image: 1
Specimen Label: CTX
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7442993
Age: postnatal day 0
Image: 1
Specimen Label: RES
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Stage: TS27
Assay Id: MGI:7442993
Age: postnatal day 0
Image: 1
Specimen Label: HIP
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CTR
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CAP1-KO
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CTR
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CAP1-KO
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CTR
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7442987
Assay Type: Western blot
Annotation Date: 2023-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444032
Age: embryonic day 18.5
Image: 1
Specimen Label: CAP1-KO
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7442991
Assay Type: RT-PCR
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444034
Age: embryonic day 18.5
Image: 1
Specimen Label: CTR
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7442991
Assay Type: RT-PCR
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7444034
Age: embryonic day 18.5
Image: 1
Specimen Label: CAP1-KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:7572883
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7572883
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7572883
Age: embryonic day 18.5
Image: 1
Specimen Label: E18.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7572883
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7572885
Age: postnatal day 0
Image: 1
Specimen Label: CTX
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Stage: TS27
Assay Id: MGI:7572885
Age: postnatal day 0
Image: 1
Specimen Label: HIP
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7572885
Age: postnatal day 0
Image: 1
Specimen Label: RES
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Stage: TS26
Assay Id: MGI:7572916
Age: embryonic day 18.5
Image: 5
Specimen Label: CTR
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7572594
Assay Type: Western blot
Annotation Date: 2024-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284526
Stage: TS26
Assay Id: MGI:7572916
Age: embryonic day 18.5
Image: 5
Specimen Label: CAP1-KO
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945015
Age: embryonic day 11.5
Image: g00460 E11.5
Specimen Label: g00460 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945015
Age: embryonic day 11.5
Image: g00460 E11.5
Specimen Label: g00460 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945015
Age: embryonic day 15.5
Image: g00460 E15.5
Specimen Label: g00460 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Note: Expression was region specific and scattered.
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 42
Image: g00460 Adult
Specimen Label: g00460 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4882618
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945015
Age: postnatal day 7
Image: g00460 P7
Specimen Label: g00460 P7
Detected: true
Specimen Num: 3