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Search results 1 to 91 out of 91 for Capn8

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
388743 | CAPN8
Type: gene
Organism: human
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Gene
733929 | capn8
Type: gene
Organism: frog, western clawed
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Gene
170808 | Capn8
Type: gene
Organism: rat
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Gene
612029 | CAPN8
Type: gene
Organism: dog, domestic
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Gene
457764 | CAPN8
Type: gene
Organism: chimpanzee
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Gene
617138 | CAPN8
Type: gene
Organism: cattle
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Gene
428561 | CAPN8
Type: gene
Organism: chicken
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Gene
337730 | capn8
Type: gene
Organism: zebrafish
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Gene
705658 | CAPN8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2181366 | Capn8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029543 | CAPN8
Type: Family
Description: Calpain-8 (CAPN8) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. Calpain-8 and Calpain-9 are predominantly expressed in the gastrointestinal tract and are restricted to the gastric surface mucus (pit) cells in the stomach. They are involved in gastric mucosal defence [, ].
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Publication
20686710 | J:163312
First Author: Hata S
Year: 2010
Journal: PLoS Genet
Title: Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.
Volume: 6
Issue: 7
Pages: e1001040
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Publication
17646163 | J:125385
First Author: Hata S
Year: 2007
Journal: J Biol Chem
Title: Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains.
Volume: 282
Issue: 38
Pages: 27847-56
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Publication
27881674 | J:237762
First Author: Hata S
Year: 2016
Journal: J Biol Chem
Title: A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively.
Volume: 291
Issue: 53
Pages: 27313-27322
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Protein
Q91VA3
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
A0A0A6YVU9
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: false
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Protein
A0A0R4J0K6
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Publication
12843408 | -
First Author: Goll DE
Year: 2003
Journal: Physiol Rev
Title: The calpain system.
Volume: 83
Issue: 3
Pages: 731-801
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Publication
24085852 | -
First Author: Jeong SY
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis.
Volume: 110
Issue: 42
Pages: E4007-15
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Publication
11523006 | J:75402
First Author: Hata S
Year: 2001
Journal: J Mol Evol
Title: Both the conserved and the unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution.
Volume: 53
Issue: 3
Pages: 191-203
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Publication
19416960 | J:152633
First Author: Harrill AH
Year: 2009
Journal: Genome Res
Title: Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.
Volume: 19
Issue: 9
Pages: 1507-15
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Protein Coding Gene
MGP_CAROLIEiJ_G0015003 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2181366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017333 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028235 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015803 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869553
Note: vas deferens
Specimen Label: UC Davis_1869553
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869544
Specimen Label: UC Davis_1869544
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869545
Specimen Label: UC Davis_1869545
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869546
Specimen Label: UC Davis_1869546
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869547
Specimen Label: UC Davis_1869547
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869548
Specimen Label: UC Davis_1869548
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869549
Specimen Label: UC Davis_1869549
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869552
Specimen Label: UC Davis_1869552
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869539
Specimen Label: UC Davis_1869539
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869540
Specimen Label: UC Davis_1869540
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869541
Specimen Label: UC Davis_1869541
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869550
Specimen Label: UC Davis_1869550
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869551
Specimen Label: UC Davis_1869551
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869543
Specimen Label: UC Davis_1869543
Detected: true
Specimen Num: 4
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Publication
16476741 | J:112682
First Author: Hata S
Year: 2006
Journal: J Biol Chem
Title: Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.
Volume: 281
Issue: 16
Pages: 11214-24
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19603510 | J:153563
First Author: Zhao Z
Year: 2009
Journal: Genesis
Title: Capn8 promoter directs the expression of Cre recombinase in gastric pit cells of transgenic mice.
Volume: 47
Issue: 10
Pages: 674-9
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Publication
- | J:74445
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 gene for stomach specific calpain nCL-2, partial cds
Pages: AB050201
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Publication
- | J:74446
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach specific calpain nCL-2, complete cds
Pages: AB050202
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Publication
- | J:74447
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach specific calpain nCL-2, complete cds
Pages: AB050203
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Publication
- | J:74448
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNa for stomach-specific calpain, splicing variant nCL-2, complete cds
Pages: AB061518
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Publication
- | J:74449
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach-specific calpain, splicing variant nCL-2, complete cds
Pages: AB061519
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Protein
Q9ESK3
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
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Protein Coding Gene
MGI:1344392 | Capn10
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Tg(Capn8-cre)1Xya | MGI:4365914
Name: transgene insertion 1, Xiao Yang
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Smad4/Smad4 Tg(Capn8-cre)1Xya/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Capn8-cre)1Xya/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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