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Search results 1 to 89 out of 89 for Capn8

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
388743 | CAPN8
Type: gene
Organism: human
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Gene
457764 | CAPN8
Type: gene
Organism: chimpanzee
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Gene
617138 | CAPN8
Type: gene
Organism: cattle
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Gene
428561 | CAPN8
Type: gene
Organism: chicken
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Gene
337730 | capn8
Type: gene
Organism: zebrafish
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Gene
705658 | CAPN8
Type: gene
Organism: macaque, rhesus
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Gene
170808 | Capn8
Type: gene
Organism: rat
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Gene
612029 | CAPN8
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2181366 | Capn8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029543 | CAPN8
Type: Family
Description: Calpain-8 (CAPN8) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. Calpain-8 and Calpain-9 are predominantly expressed in the gastrointestinal tract and are restricted to the gastric surface mucus (pit) cells in the stomach. They are involved in gastric mucosal defence [, ].
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Publication
20686710 | J:163312
First Author: Hata S
Year: 2010
Journal: PLoS Genet
Title: Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.
Volume: 6
Issue: 7
Pages: e1001040
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Publication
17646163 | J:125385
First Author: Hata S
Year: 2007
Journal: J Biol Chem
Title: Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains.
Volume: 282
Issue: 38
Pages: 27847-56
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Publication
27881674 | J:237762
First Author: Hata S
Year: 2016
Journal: J Biol Chem
Title: A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively.
Volume: 291
Issue: 53
Pages: 27313-27322
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Protein
Q91VA3
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
A0A0A6YVU9
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: false
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Protein
A0A0R4J0K6
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Publication
12843408 | -
First Author: Goll DE
Year: 2003
Journal: Physiol Rev
Title: The calpain system.
Volume: 83
Issue: 3
Pages: 731-801
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Publication
24085852 | -
First Author: Jeong SY
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis.
Volume: 110
Issue: 42
Pages: E4007-15
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Publication
11523006 | J:75402
First Author: Hata S
Year: 2001
Journal: J Mol Evol
Title: Both the conserved and the unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution.
Volume: 53
Issue: 3
Pages: 191-203
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Publication
19416960 | J:152633
First Author: Harrill AH
Year: 2009
Journal: Genome Res
Title: Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.
Volume: 19
Issue: 9
Pages: 1507-15
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Protein Coding Gene
MGP_CAROLIEiJ_G0015003 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2181366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017333 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028235 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015803 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869553
Note: vas deferens
Specimen Label: UC Davis_1869553
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869544
Specimen Label: UC Davis_1869544
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869545
Specimen Label: UC Davis_1869545
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869546
Specimen Label: UC Davis_1869546
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869547
Specimen Label: UC Davis_1869547
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869548
Specimen Label: UC Davis_1869548
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869549
Specimen Label: UC Davis_1869549
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869552
Specimen Label: UC Davis_1869552
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869539
Specimen Label: UC Davis_1869539
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869540
Specimen Label: UC Davis_1869540
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869541
Specimen Label: UC Davis_1869541
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869550
Specimen Label: UC Davis_1869550
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869551
Specimen Label: UC Davis_1869551
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692507
Age: postnatal adult
Image: UC Davis_1869543
Specimen Label: UC Davis_1869543
Detected: true
Specimen Num: 4
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Publication
16476741 | J:112682
First Author: Hata S
Year: 2006
Journal: J Biol Chem
Title: Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.
Volume: 281
Issue: 16
Pages: 11214-24
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19603510 | J:153563
First Author: Zhao Z
Year: 2009
Journal: Genesis
Title: Capn8 promoter directs the expression of Cre recombinase in gastric pit cells of transgenic mice.
Volume: 47
Issue: 10
Pages: 674-9
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Publication
- | J:74445
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 gene for stomach specific calpain nCL-2, partial cds
Pages: AB050201
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Publication
- | J:74446
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach specific calpain nCL-2, complete cds
Pages: AB050202
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Publication
- | J:74447
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach specific calpain nCL-2, complete cds
Pages: AB050203
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Publication
- | J:74448
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNa for stomach-specific calpain, splicing variant nCL-2, complete cds
Pages: AB061518
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Publication
- | J:74449
   
First Author: Hata S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Capn8 mRNA for stomach-specific calpain, splicing variant nCL-2, complete cds
Pages: AB061519
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Protein
Q9ESK3
Organism: Mus musculus/domesticus
Length: 666  
Fragment?: false
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Protein Coding Gene
MGI:1344392 | Capn10
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Tg(Capn8-cre)1Xya | MGI:4365914
Name: transgene insertion 1, Xiao Yang
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Smad4/Smad4 Tg(Capn8-cre)1Xya/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Capn8-cre)1Xya/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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