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Search results 1 to 100 out of 185 for Capzb

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: The F-actin capping protein binds in a calcium-independent manner to the fast growing ends of actin filaments (barbed end) and thereby restricts its growth. The F-actin capping protein is a heterodimer composed of two unrelated subunits: alpha and beta. Neither of the subunits shows sequence similarity to other filament-capping proteins [].This entry represents the beta subunit (CAPZB), which is a protein of about 280 amino acid residues whose sequence is well conserved in eukaryotic species []. In Drosophila mutations in the alpha and beta subunits cause actin accumulation and subsequent retinal degeneration []. In humans CAPZB is part of the WASH complex that controls the fission of endosomes [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
Publication
First Author: Amatruda JF
Year: 1990
Journal: Nature
Title: Disruption of the actin cytoskeleton in yeast capping protein mutants.
Volume: 344
Issue: 6264
Pages: 352-4
Publication
First Author: Maruyama K
Year: 1990
Journal: J Biol Chem
Title: Beta-actinin is equivalent to Cap Z protein.
Volume: 265
Issue: 15
Pages: 8712-5
Publication
First Author: Delalle I
Year: 2005
Journal: Genetics
Title: Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration.
Volume: 171
Issue: 4
Pages: 1757-65
Publication
First Author: Derivery E
Year: 2009
Journal: Dev Cell
Title: The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.
Volume: 17
Issue: 5
Pages: 712-23
Publication
First Author: Avenarius MR
Year: 2017
Journal: J Cell Biol
Title: Heterodimeric capping protein is required for stereocilia length and width regulation.
Volume: 216
Issue: 11
Pages: 3861-3881
Publication
First Author: Geyer CB
Year: 2009
Journal: Dev Biol
Title: A missense mutation in the Capza3 gene and disruption of F-actin organization in spermatids of repro32 infertile male mice.
Volume: 330
Issue: 1
Pages: 142-52
Publication
First Author: Pocaterra A
Year: 2019
Journal: J Hepatol
Title: F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
Volume: 71
Issue: 1
Pages: 130-142
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schafer DA
Year: 1994
Journal: J Cell Biol
Title: Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates.
Volume: 127
Issue: 2
Pages: 453-65
Publication
First Author: von Bülow M
Year: 1997
Journal: Exp Cell Res
Title: CP beta3, a novel isoform of an actin-binding protein, is a component of the cytoskeletal calyx of the mammalian sperm head.
Volume: 233
Issue: 1
Pages: 216-24
Publication
First Author: Kitanishi T
Year: 2010
Journal: Genes Cells
Title: Activity-dependent localization in spines of the F-actin capping protein CapZ screened in a rat model of dementia.
Volume: 15
Issue: 7
Pages: 737-47
Publication
First Author: Pyle WG
Year: 2002
Journal: Circ Res
Title: Actin capping protein: an essential element in protein kinase signaling to the myofilaments.
Volume: 90
Issue: 12
Pages: 1299-306
Publication
First Author: Hart MC
Year: 1999
Journal: J Cell Biol
Title: Vertebrate isoforms of actin capping protein beta have distinct functions In vivo.
Volume: 147
Issue: 6
Pages: 1287-98
Publication  
First Author: Hart MC
Year: 2000
Journal: BMC Genomics
Title: Mapping of the mouse actin capping protein beta subunit gene.
Volume: 1
Pages: 1
Publication
First Author: Yang FH
Year: 2012
Journal: J Mol Cell Cardiol
Title: Reduced cardiac CapZ protein protects hearts against acute ischemia-reperfusion injury and enhances preconditioning.
Volume: 52
Issue: 3
Pages: 761-72
Publication
First Author: Ye Z
Year: 2021
Journal: Oncogene
Title: Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ.
Volume: 40
Issue: 10
Pages: 1775-1791
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:6117862
Age: embryonic day 16.0
Image: S2
Specimen Label: Cortex E16
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6117862
Age: postnatal adult
Image: S2
Specimen Label: Cortex Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:6117863
Age: embryonic day 16.0
Image: S2
Specimen Label: Cortex E16
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6117863
Age: postnatal adult
Image: S2
Specimen Label: Cortex Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7543675
Assay Type: RT-PCR
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598826
Stage: TS26
Assay Id: MGI:7543713
Age: embryonic day 18.5
Image: 2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7543675
Assay Type: RT-PCR
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598826
Stage: TS26
Assay Id: MGI:7543713
Age: embryonic day 18.5
Image: 2
Specimen Label: KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:6117862
Age: embryonic day 16.0
Image: S2
Specimen Label: Hippocampus E16
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6117862
Age: postnatal adult
Image: S2
Specimen Label: Hippocampus Adult
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:6117863
Age: embryonic day 16.0
Image: S2
Specimen Label: Hippocampus E16
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6117863
Age: postnatal adult
Image: S2
Specimen Label: Hippocampus Adult
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3831841
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3831841
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3831841
Age: postnatal day 1
Image: 1
Specimen Label: PN1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3831841
Age: postnatal day 3
Image: 1
Specimen Label: PN3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3831841
Age: postnatal month 3
Image: 1
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3832024
Age: embryonic day 14.0
Image: S4
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3832024
Age: embryonic day 18.0
Image: S4
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3832024
Age: postnatal day 1
Image: S4
Specimen Label: PN1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3832024
Age: postnatal day 3
Image: S4
Specimen Label: PN3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832024
Age: postnatal month 3
Image: S4
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3832241
Age: embryonic day 14.0
Image: S7
Specimen Label: E14 wt h
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3832241
Age: embryonic day 14.0
Image: S7
Specimen Label: E14 wt i
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal adult
Image: S7
Specimen Label: Adult +/+ j
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal adult
Image: S7
Specimen Label: Adult +/+ k
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal
Image: S7
Specimen Label: MBNL1 +/- l
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal
Image: S7
Specimen Label: MBNL1 +/- m
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal
Image: S7
Specimen Label: delta3/delta3 n
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3831767
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832241
Age: postnatal
Image: S7
Specimen Label: delta3/delta3 o
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6117859
Age: postnatal adult
Image: 4
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6117859
Age: postnatal adult
Image: 4
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6117859
Age: postnatal adult
Image: 4
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6117861
Age: postnatal adult
Image: 4
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6117834
Assay Type: Western blot
Annotation Date: 2018-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6117861
Age: postnatal adult
Image: 4
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1706823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_10
Specimen Label: euxassay_011596_10
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_10
Specimen Label: euxassay_011596_10
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_11
Specimen Label: euxassay_011596_11
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_12
Specimen Label: euxassay_011596_12
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_13
Specimen Label: euxassay_011596_13
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_14
Specimen Label: euxassay_011596_14
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4417033
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823622
Age: embryonic day 14.5
Image: euxassay_011596_15
Specimen Label: euxassay_011596_15
Detected: true
Specimen Num: 6
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, capping protein (actin filament) muscle Z-line, beta, clone MGC: 6082, mRNA, complete cds
Pages: BC002053
Publication
First Author: Kuhn JR
Year: 2007
Journal: J Biol Chem
Title: Single molecule kinetic analysis of actin filament capping. Polyphosphoinositides do not dissociate capping proteins.
Volume: 282
Issue: 38
Pages: 28014-24
Publication
First Author: Jo YJ
Year: 2015
Journal: J Cell Sci
Title: Actin-capping proteins play essential roles in the asymmetric division of maturing mouse oocytes.
Volume: 128
Issue: 1
Pages: 160-70
Publication
First Author: Gong TW
Year: 1997
Journal: Biochim Biophys Acta
Title: Complete cDNAs for CDC42 from chicken cochlea and mouse liver.
Volume: 1352
Issue: 3
Pages: 282-92
Publication
First Author: Eyers CE
Year: 2005
Journal: Biochem J
Title: The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ.
Volume: 389
Issue: Pt 1
Pages: 127-35