|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 40 out of 40 for Cars

0.023s
Type Details Score
Gene
Type: gene
Organism: chicken
Protein Domain
Type: Family
Description: This entry includes the CDP-archaeol synthase from archaea and a group of putative integral membrane proteins from bacteria. CDP-archaeol synthase functions in the archaeal lipid biosynthetic pathway. It catalyses the transfer of the nucleotide to its specific archaeal lipid substrate, leading to the formation of a CDP-activated precursor (CDP-archaeol) to which polar head groups are attached [].
Publication
First Author: Jain S
Year: 2014
Journal: Chem Biol
Title: Identification of CDP-archaeol synthase, a missing link of ether lipid biosynthesis in Archaea.
Volume: 21
Issue: 10
Pages: 1392-1401
Publication
First Author: Whitworth DE
Year: 2001
Journal: Mol Microbiol
Title: Light-induced carotenogenesis in Myxococcus xanthus: evidence that CarS acts as an anti-repressor of CarA.
Volume: 42
Issue: 3
Pages: 809-19
Publication
First Author: Navarro-Avilés G
Year: 2007
Journal: Mol Microbiol
Title: Structural basis for operator and antirepressor recognition by Myxococcus xanthus CarA repressor.
Volume: 63
Issue: 4
Pages: 980-94
Publication
First Author: López-Rubio JJ
Year: 2002
Journal: J Biol Chem
Title: A repressor-antirepressor pair links two loci controlling light-induced carotenogenesis in Myxococcus xanthus.
Volume: 277
Issue: 9
Pages: 7262-70
Protein Domain
Type: Domain
Description: CarS, an antirepressor present in Cystobacterineae, recognizes repressors to turn on the photo-inducible promoter P(B). In the dark, access to the P(B) promoter is blocked by the repressor CarA []. Blue light causes expression of CarS, leading the way to the CarA-CarS interaction which dismantles the CarA-operator complex, resulting in the derepression of the P(B) promoter [, ]. A parallel pathway for regulating P(B) involves the interaction of CarS with the repressor CarH, which shares the domain architecture of CarA. CarH and CarA contain an N-terminal, MerR-type winged-helix DNA-binding domain that recognizes CarS. CarS adopts an SH3-like fold with loop length variations and acts as an operator DNA mimic [].
Protein
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: true
Publication
First Author: León E
Year: 2010
Journal: Nucleic Acids Res
Title: A bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helix.
Volume: 38
Issue: 15
Pages: 5226-41
Publication
First Author: Lim RS
Year: 2011
Journal: J Lipid Res
Title: Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging.
Volume: 52
Issue: 12
Pages: 2177-86
Publication  
First Author: Tolstik E
Year: 2022
Journal: Int J Mol Sci
Title: CARS Imaging Advances Early Diagnosis of Cardiac Manifestation of Fabry Disease.
Volume: 23
Issue: 10
Publication
First Author: Harris DT
Year: 2018
Journal: J Immunol
Title: Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.
Volume: 200
Issue: 3
Pages: 1088-1100
Publication
First Author: Lim RS
Year: 2010
Journal: J Lipid Res
Title: Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice.
Volume: 51
Issue: 7
Pages: 1729-37
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: false
Allele
Name: cysteinyl-tRNA synthetase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Domain
Type: Domain
Description: This is an SH3 domain found in antirepressor proteins such as CarS from Myxococcus xanthus. CarS antirepressor recognizes and neutralizes its cognate repressors to turn on a photo-inducible promoter. CarS physically interacts with the MerR-type winged-helix DNA-binding domain of these repressors leading to activation of carB operon. Structural studies of CarS from M. Xanthus reveals a β-barrel fold akin to that in SH3 domains. However, it diverges from the typical SH3 domain fold in the lengths and conformations of the connecting loops. Functional analysis reveal that SH3 domain-like fold in the antirepressor CasS, mimics operator DNA in sequestering the repressor DNA recognition helix to activate transcription [].
Publication
First Author: Rodriguez L
Year: 2014
Journal: Plant Cell
Title: C2-domain abscisic acid-related proteins mediate the interaction of PYR/PYL/RCAR abscisic acid receptors with the plasma membrane and regulate abscisic acid sensitivity in Arabidopsis.
Volume: 26
Issue: 12
Pages: 4802-20
Publication
First Author: Yung YL
Year: 2015
Journal: J Biol Chem
Title: Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1).
Volume: 290
Issue: 39
Pages: 23984-96
Protein Domain
Type: Family
Description: CarS (CDP-archaeol synthase) is a membrane protein that functions in the archaeal lipid biosynthetic pathway. It catalyses the transfer of the nucleotide to its specific archaeal lipid substrate, leading to the formation of a CDP-activated precursor (CDP-archaeol) to which polar head groups are attached [].
Protein Domain
Type: Family
Description: This entry includes C2-domain abscisic acid-related protein CAR1-11 from Arabidopsis and GTPase activating protein 1 (OsGAP1) from rice. CARs interact with the PYR/PYL ABA receptors and recruit them to membranes in a Ca2+-dependent manner []. OsGAP1 is a soluble protein that can loosely associate with plasma membrane. It can also interact with an unconventional G-protein, OsYchF1, and stimulate its NTPase activities [].
Allele
Name: transgene insertion 1952, Andrea Riccio
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Long AH
Year: 2015
Journal: Nat Med
Title: 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
Volume: 21
Issue: 6
Pages: 581-90
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Kato R
Year: 1999
Journal: DNA Res
Title: Sequence-ready 1-Mb YAC, BAC and cosmid contigs covering the distal imprinted region of mouse chromosome 7.
Volume: 6
Issue: 6
Pages: 401-5
Publication
First Author: Cerrato F
Year: 2005
Journal: Hum Mol Genet
Title: The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster.
Volume: 14
Issue: 4
Pages: 503-11
Genotype
Symbol: Tg(YACW408A5)1952Ricc/?
Background: involves: 129/Sv * SD7
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Chang W
Year: 1999
Journal: Endocrinology
Title: Expression and signal transduction of calcium-sensing receptors in cartilage and bone.
Volume: 140
Issue: 12
Pages: 5883-93
Publication  
First Author: Wang H
Year: 2016
Journal: Sci Rep
Title: In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin.
Volume: 6
Pages: 37986
Publication
First Author: Szade K
Year: 2020
Journal: EMBO Rep
Title: Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.
Volume: 21
Issue: 2
Pages: e47895
Publication
First Author: Oshima K
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.
Volume: 317
Issue: 5
Pages: L667-L677
Publication
First Author: Cheng Z
Year: 2007
Journal: Endocrinology
Title: Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes.
Volume: 148
Issue: 10
Pages: 4984-92
Publication
First Author: Riese MJ
Year: 2013
Journal: Cancer Res
Title: Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases.
Volume: 73
Issue: 12
Pages: 3566-77
Publication
First Author: Rodriguez L
Year: 2005
Journal: Endocrinology
Title: Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes.
Volume: 146
Issue: 12
Pages: 5294-303
Publication
First Author: Lee JC
Year: 2011
Journal: Cancer Res
Title: In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy.
Volume: 71
Issue: 8
Pages: 2871-81
Publication
First Author: Ghosh A
Year: 2017
Journal: Nat Med
Title: Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.
Volume: 23
Issue: 2
Pages: 242-249
Publication
First Author: Lee B
Year: 2009
Journal: Biochim Biophys Acta
Title: Differential association of adipophilin and TIP47 proteins with cytoplasmic lipid droplets in mouse enterocytes during dietary fat absorption.
Volume: 1791
Issue: 12
Pages: 1173-80
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China