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Search results 1 to 100 out of 965 for Casp1

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Type Details Score
Gene
834 | CASP1
Type: gene
Organism: human
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Gene
514214 | CASP1
Type: gene
Organism: cattle
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Gene
101058924 | CASP1
Type: gene
Organism: chimpanzee
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Gene
395764 | CASP1
Type: gene
Organism: chicken
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Gene
100491605 | casp1
Type: gene
Organism: frog, western clawed
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Gene
25166 | Casp1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:96544 | Casp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32002713 | J:296047
First Author: Mirea AM
Year: 2020
Journal: Inflammation
Title: Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.
Volume: 43
Issue: 3
Pages: 1054-1064
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UniProt Feature
UniProt Feature
Begin: 67
Description: Cleavage; by CASP1
Type: site
End: 68
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Publication
9120399 | J:38779
First Author: Friedlander RM
Year: 1997
Journal: J Exp Med
Title: Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury.
Volume: 185
Issue: 5
Pages: 933-40
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Publication
10208603 | J:56231
First Author: Klevenyi P
Year: 1999
Journal: Neuroreport
Title: Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity.
Volume: 10
Issue: 3
Pages: 635-8
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Publication
10899963 | J:63441
First Author: Andreassen OA
Year: 2000
Journal: J Neurochem
Title: Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.
Volume: 75
Issue: 2
Pages: 847-52
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Publication
23226472 | J:192443
First Author: Hesker PR
Year: 2012
Journal: PLoS One
Title: Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels.
Volume: 7
Issue: 11
Pages: e51105
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Publication
33414187 | J:304358
 
First Author: Chuang HC
Year: 2021
Journal: eNeuro
Title: Lytic Cell Death in Specific Microglial Subsets Is Required for Preventing Atypical Behavior in Mice.
Volume: 8
Issue: 1
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Publication
24312444 | J:209749
First Author: Hendrikx T
Year: 2013
Journal: PLoS One
Title: Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Volume: 8
Issue: 12
Pages: e78792
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Publication
20876354 | J:165191
First Author: Labbé K
Year: 2010
Journal: J Immunol
Title: Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling.
Volume: 185
Issue: 9
Pages: 5495-502
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Publication
16974082 | J:112879
First Author: Gehrig A
Year: 2006
Journal: Cytogenet Genome Res
Title: The role of caspases in photoreceptor cell death of the retinoschisin-deficient mouse.
Volume: 115
Issue: 1
Pages: 35-44
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Publication
36220815 | J:330039
First Author: Flores J
Year: 2022
Journal: Cell Death Dis
Title: Caspase-1 inhibition improves cognition without significantly altering amyloid and inflammation in aged Alzheimer disease mice.
Volume: 13
Issue: 10
Pages: 864
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Publication
17409187 | J:120877
First Author: Mastronardi C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Caspase 1 deficiency reduces inflammation-induced brain transcription.
Volume: 104
Issue: 17
Pages: 7205-10
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Publication
14693703 | J:87250
First Author: Schott WH
Year: 2004
Journal: Diabetes
Title: Caspase-1 is not required for type 1 diabetes in the NOD mouse.
Volume: 53
Issue: 1
Pages: 99-104
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Publication
22002608 | J:193522
First Author: Kayagaki N
Year: 2011
Journal: Nature
Title: Non-canonical inflammasome activation targets caspase-11.
Volume: 479
Issue: 7371
Pages: 117-21
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Publication
20226691 | J:158664
First Author: Dupaul-Chicoine J
Year: 2010
Journal: Immunity
Title: Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases.
Volume: 32
Issue: 3
Pages: 367-78
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Publication
32101731 | J:288227
First Author: Reinke S
Year: 2020
Journal: Cell Rep
Title: Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo.
Volume: 30
Issue: 8
Pages: 2501-2511.e5
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Publication
31251782 | J:324736
First Author: Gonçalves AV
Year: 2019
Journal: PLoS Pathog
Title: Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Volume: 15
Issue: 6
Pages: e1007886
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Publication
26968342 | J:231908
First Author: Nastase MV
Year: 2016
Journal: Am J Pathol
Title: An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis.
Volume: 186
Issue: 5
Pages: 1206-20
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Publication
36641116 | J:336303
First Author: Ioannou GN
Year: 2023
Journal: J Lipid Res
Title: Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH.
Volume: 64
Issue: 2
Pages: 100330
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Publication
25633245 | J:345748
First Author: Mastronardi CA
Year: 2015
Journal: Neuroimmunomodulation
Title: Temporal gene expression in the hippocampus and peripheral organs to endotoxin-induced systemic inflammatory response in caspase-1-deficient mice.
Volume: 22
Issue: 4
Pages: 263-73
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Publication
25744023 | J:258544
First Author: Kaushal V
Year: 2015
Journal: Cell Death Differ
Title: Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
Volume: 22
Issue: 10
Pages: 1676-86
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Publication
22902502 | J:188134
First Author: von Moltke J
Year: 2012
Journal: Nature
Title: Rapid induction of inflammatory lipid mediators by the inflammasome in vivo.
Volume: 490
Issue: 7418
Pages: 107-11
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Publication
35990890 | J:328218
 
First Author: Chehade L
Year: 2022
Journal: Front Cell Neurosci
Title: Suppression of the necroptotic cell death pathways improves survival in Smn 2B/- mice.
Volume: 16
Pages: 972029
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Publication
26687278 | J:228423
 
First Author: Cunha LD
Year: 2015
Journal: Nat Commun
Title: Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.
Volume: 6
Pages: 10205
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Publication
28771586 | J:283562
First Author: Mascarenhas DPA
Year: 2017
Journal: PLoS Pathog
Title: Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.
Volume: 13
Issue: 8
Pages: e1006502
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Publication
31063608 | J:280822
First Author: de Carvalho RVH
Year: 2019
Journal: J Leukoc Biol
Title: Macrophage priming is dispensable for NLRP3 inflammasome activation and restriction of Leishmania amazonensis replication.
Volume: 106
Issue: 3
Pages: 631-640
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Publication
31029578 | J:275922
 
First Author: Alarcon MML
Year: 2019
Journal: J Mol Cell Cardiol
Title: Cardiac arrhythmias after renal I/R depend on IL-1β.
Volume: 131
Pages: 101-111
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Publication
22753929 | J:189777
First Author: Kovarova M
Year: 2012
Journal: J Immunol
Title: NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice.
Volume: 189
Issue: 4
Pages: 2006-16
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Publication
34437534 | J:309361
First Author: Zhang Y
Year: 2021
Journal: PLoS Biol
Title: A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.
Volume: 19
Issue: 8
Pages: e3001304
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Publication
24739961 | J:210626
First Author: Meunier E
Year: 2014
Journal: Nature
Title: Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Volume: 509
Issue: 7500
Pages: 366-70
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Publication
27998728 | J:240185
First Author: Sharma D
Year: 2017
Journal: Am J Pathol
Title: IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever.
Volume: 187
Issue: 2
Pages: 236-244
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Publication
28410991 | J:255168
First Author: Rauch I
Year: 2017
Journal: Immunity
Title: NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.
Volume: 46
Issue: 4
Pages: 649-659
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Publication
25704009 | J:287726
First Author: Karki R
Year: 2015
Journal: Cell Host Microbe
Title: Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.
Volume: 17
Issue: 3
Pages: 357-368
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Publication
23887873 | J:201075
First Author: Kayagaki N
Year: 2013
Journal: Science
Title: Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Volume: 341
Issue: 6151
Pages: 1246-9
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Publication
24453255 | J:209447
First Author: Gurung P
Year: 2014
Journal: J Immunol
Title: FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.
Volume: 192
Issue: 4
Pages: 1835-46
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Protein Coding Gene
MGP_CAROLIEiJ_G0031743 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034219 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96544 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034805 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034124 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034069 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014622 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032863 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8034321 | J:17638
First Author: Casano FJ
Year: 1994
Journal: Genomics
Title: The structure and complete nucleotide sequence of the murine gene encoding interleukin-1 beta converting enzyme (ICE).
Volume: 20
Issue: 3
Pages: 474-81
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Publication
21147462 | J:306581
First Author: Broz P
Year: 2010
Journal: Cell Host Microbe
Title: Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing.
Volume: 8
Issue: 6
Pages: 471-83
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Publication
10051653 | J:113808
First Author: Hersh D
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1.
Volume: 96
Issue: 5
Pages: 2396-401
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Publication
7610484 | J:25555
First Author: Kumar S
Year: 1995
Journal: Trends Biochem Sci
Title: ICE-like proteases in apoptosis.
Volume: 20
Issue: 5
Pages: 198-202
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Publication
25127135 | J:297265
First Author: Liu T
Year: 2014
Journal: Cell Rep
Title: Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.
Volume: 8
Issue: 4
Pages: 974-82
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Publication
31085641 | J:275608
First Author: Kudo E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Low ambient humidity impairs barrier function and innate resistance against influenza infection.
Volume: 116
Issue: 22
Pages: 10905-10910
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Publication
10353249 | J:55036
First Author: Ona VO
Year: 1999
Journal: Nature
Title: Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease.
Volume: 399
Issue: 6733
Pages: 263-7
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Publication
11418486 | J:70749
First Author: Itoi H
Year: 2001
Journal: Blood
Title: Fas ligand-induced caspase-1-dependent accumulation of interleukin-18 in mice with acute graft-versus-host disease.
Volume: 98
Issue: 1
Pages: 235-7
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Publication
32613271 | J:309363
First Author: Barber G
Year: 2020
Journal: Cancer Immunol Immunother
Title: Characterizing caspase-1 involvement during esophageal disease progression.
Volume: 69
Issue: 12
Pages: 2635-2649
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Publication
7535475 | J:24258
First Author: Kuida K
Year: 1995
Journal: Science
Title: Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
Volume: 267
Issue: 5206
Pages: 2000-3
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Publication
20823203 | J:165027
First Author: Wangdi T
Year: 2010
Journal: Infect Immun
Title: In vivo discrimination of type 3 secretion system-positive and -negative Pseudomonas aeruginosa via a caspase-1-dependent pathway.
Volume: 78
Issue: 11
Pages: 4744-53
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Publication
27015566 | J:248540
First Author: Periasamy S
Year: 2016
Journal: PLoS Pathog
Title: An Immature Myeloid/Myeloid-Suppressor Cell Response Associated with Necrotizing Inflammation Mediates Lethal Pulmonary Tularemia.
Volume: 12
Issue: 3
Pages: e1005517
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Publication
8999548 | J:298991
First Author: Gu Y
Year: 1997
Journal: Science
Title: Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme.
Volume: 275
Issue: 5297
Pages: 206-9
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Publication
11606779 | J:72540
First Author: Siegmund B
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.
Volume: 98
Issue: 23
Pages: 13249-54
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Publication
22837397 | J:188714
First Author: Ko DC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
Volume: 109
Issue: 35
Pages: E2343-52
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Publication
15644489 | J:97733
First Author: Wang W
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice.
Volume: 288
Issue: 5
Pages: F997-1004
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Publication
15590467 | J:94634
First Author: Thakur A
Year: 2004
Journal: Curr Eye Res
Title: Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
Volume: 29
Issue: 4-5
Pages: 225-33
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Publication
28126413 | J:239600
 
First Author: Jessop F
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity.
Volume: 318
Pages: 58-68
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Publication
26037927 | J:223379
First Author: Lopez-Pastrana J
Year: 2015
Journal: J Biol Chem
Title: Inhibition of Caspase-1 Activation in Endothelial Cells Improves Angiogenesis: A NOVEL THERAPEUTIC POTENTIAL FOR ISCHEMIA.
Volume: 290
Issue: 28
Pages: 17485-94
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Publication
22143773 | J:325789
First Author: Stewart MK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response.
Volume: 108
Issue: 51
Pages: 20742-7
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Publication
29891920 | J:263068
First Author: Glennon EKK
Year: 2018
Journal: Sci Rep
Title: Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.
Volume: 8
Issue: 1
Pages: 8896
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Publication
10491411 | J:115310
First Author: Fantuzzi G
Year: 1999
Journal: J Clin Invest
Title: IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Volume: 104
Issue: 6
Pages: 761-7
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Publication
25017793 | J:218491
First Author: Gao P
Year: 2014
Journal: Biochim Biophys Acta
Title: Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy.
Volume: 1843
Issue: 11
Pages: 2448-60
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Publication
19179418 | J:147167
First Author: Breitbach K
Year: 2009
Journal: Infect Immun
Title: Caspase-1 mediates resistance in murine melioidosis.
Volume: 77
Issue: 4
Pages: 1589-95
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Publication
23409132 | J:198314
First Author: Dixon LJ
Year: 2013
Journal: PLoS One
Title: Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis.
Volume: 8
Issue: 2
Pages: e56100
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Publication
19487481 | J:151327
First Author: Liu N
Year: 2009
Journal: Infect Immun
Title: The caspase 1 inflammasome is not required for control of murine Lyme borreliosis.
Volume: 77
Issue: 8
Pages: 3320-7
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Publication
21804020 | J:177980
First Author: Bergsbaken T
Year: 2011
Journal: J Immunol
Title: Coordinated host responses during pyroptosis: caspase-1-dependent lysosome exocytosis and inflammatory cytokine maturation.
Volume: 187
Issue: 5
Pages: 2748-54
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Publication
28974683 | J:250127
First Author: Niu Z
Year: 2017
Journal: Nat Commun
Title: Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs.
Volume: 8
Issue: 1
Pages: 766
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Publication
14734619 | J:88971
First Author: Tsuji NM
Year: 2004
Journal: Int Immunol
Title: Roles of caspase-1 in Listeria infection in mice.
Volume: 16
Issue: 2
Pages: 335-43
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Publication
23160218 | J:192450
First Author: van Diepen JA
Year: 2013
Journal: J Lipid Res
Title: Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion.
Volume: 54
Issue: 2
Pages: 448-56
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Publication
34734155 | J:341007
 
First Author: Devant P
Year: 2021
Journal: Sci Immunol
Title: Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β converting enzyme.
Volume: 6
Issue: 62
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Publication
22411067 | J:183394
First Author: Dixon LJ
Year: 2012
Journal: Lab Invest
Title: Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.
Volume: 92
Issue: 5
Pages: 713-23
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Publication
24595140 | J:209868
First Author: Hopf V
Year: 2014
Journal: Infect Immun
Title: BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomallei.
Volume: 82
Issue: 5
Pages: 2006-15
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Publication
7859282 | J:22964
First Author: Li P
Year: 1995
Journal: Cell
Title: Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock.
Volume: 80
Issue: 3
Pages: 401-11
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Publication
10869851 | J:118715
First Author: de Bilbao F
Year: 2000
Journal: Neuroscience
Title: In vivo study of motoneuron death induced by nerve injury in mice deficient in the caspase 1/ interleukin-1 beta-converting enzyme.
Volume: 98
Issue: 3
Pages: 573-83
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Publication
18025098 | J:130235
First Author: Cheng W
Year: 2008
Journal: Infect Immun
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