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Search results 1 to 100 out of 256 for Casq2

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0.03s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Knollmann BC
Year: 2006
Journal: J Clin Invest
Title: Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia.
Volume: 116
Issue: 9
Pages: 2510-20
Publication
First Author: Kalyanasundaram A
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.
Volume: 302
Issue: 1
Pages: H253-61
Publication
First Author: Eckey K
Year: 2010
Journal: Cell Physiol Biochem
Title: Modulation of human ether a gogo related channels by CASQ2 contributes to etiology of catecholaminergic polymorphic ventricular tachycardia (CPVT).
Volume: 26
Issue: 4-5
Pages: 503-12
Publication
First Author: Flores DJ
Year: 2018
Journal: Hum Mol Genet
Title: Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.
Volume: 27
Issue: 9
Pages: 1533-1544
Publication
First Author: Liu B
Year: 2015
Journal: Cardiovasc Res
Title: Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.
Volume: 108
Issue: 2
Pages: 299-311
Publication
First Author: Manno C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle.
Volume: 114
Issue: 4
Pages: E638-E647
Publication
First Author: Scorzeto M
Year: 2013
Journal: PLoS One
Title: Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.
Volume: 8
Issue: 10
Pages: e74919
Publication
First Author: Valle G
Year: 2014
Journal: Exp Cell Res
Title: Post-natal heart adaptation in a knock-in mouse model of calsequestrin 2-linked recessive catecholaminergic polymorphic ventricular tachycardia.
Volume: 321
Issue: 2
Pages: 178-89
Publication
First Author: Mosca B
Year: 2016
Journal: J Biol Chem
Title: Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.
Volume: 291
Issue: 28
Pages: 14555-65
Publication
First Author: Kalyanasundaram A
Year: 2010
Journal: J Biol Chem
Title: The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering.
Volume: 285
Issue: 5
Pages: 3076-83
Publication
First Author: Katz G
Year: 2013
Journal: Biochem Pharmacol
Title: The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).
Volume: 86
Issue: 11
Pages: 1576-83
Publication
First Author: Chopra N
Year: 2007
Journal: Circ Res
Title: Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.
Volume: 101
Issue: 6
Pages: 617-26
Publication
First Author: Rizzi N
Year: 2008
Journal: Circ Res
Title: Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model.
Volume: 103
Issue: 3
Pages: 298-306
Publication
First Author: Faggioni M
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Calsequestrin 2 and arrhythmias.
Volume: 302
Issue: 6
Pages: H1250-60
Publication
First Author: Yarotskyy V
Year: 2013
Journal: PLoS One
Title: Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.
Volume: 8
Issue: 10
Pages: e77633
Publication
First Author: Song L
Year: 2007
Journal: J Clin Invest
Title: Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.
Volume: 117
Issue: 7
Pages: 1814-23
Publication  
First Author: Kryshtal DO
Year: 2015
Journal: J Mol Cell Cardiol
Title: Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2.
Volume: 82
Pages: 75-83
Publication
First Author: Zhang J
Year: 2014
Journal: Biochem J
Title: The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.
Volume: 461
Issue: 1
Pages: 99-106
Publication
First Author: Kalyanasundaram A
Year: 2013
Journal: Cardiovasc Res
Title: Up-regulation of sarcoplasmic reticulum Ca(2+) uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2.
Volume: 98
Issue: 2
Pages: 297-306
Publication  
First Author: Deb A
Year: 2023
Journal: Cells
Title: Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease.
Volume: 12
Issue: 2
Publication
First Author: Chopra N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Volume: 106
Issue: 18
Pages: 7636-41
Publication
First Author: Denegri M
Year: 2012
Journal: Circ Res
Title: Viral gene transfer rescues arrhythmogenic phenotype and ultrastructural abnormalities in adult calsequestrin-null mice with inherited arrhythmias.
Volume: 110
Issue: 5
Pages: 663-8
Publication
First Author: Tow BD
Year: 2022
Journal: Cardiovasc Res
Title: SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release.
Volume: 118
Issue: 13
Pages: 2819-2832
Publication    
First Author: Wan Y
Year: 2019
Journal: J Histochem Cytochem
Title: Localization of Tfap2β, Casq2, Penk, Zic1, and Zic3 Expression in the Developing Retina, Muscle, and Sclera of the Embryonic Mouse Eye.
Pages: 22155419885112
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jones LR
Year: 1998
Journal: J Clin Invest
Title: Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin.
Volume: 101
Issue: 7
Pages: 1385-93
Publication
First Author: Cho MC
Year: 1999
Journal: J Biol Chem
Title: Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression.
Volume: 274
Issue: 32
Pages: 22251-6
Publication
First Author: Murphy RM
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Quantification of calsequestrin 2 (CSQ2) in sheep cardiac muscle and Ca2+-binding protein changes in CSQ2 knockout mice.
Volume: 300
Issue: 2
Pages: H595-604
Publication
First Author: Batiste SM
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic.
Volume: 116
Issue: 11
Pages: 4810-4815
Publication
First Author: Petrosino JM
Year: 2016
Journal: PLoS One
Title: Graded Maximal Exercise Testing to Assess Mouse Cardio-Metabolic Phenotypes.
Volume: 11
Issue: 2
Pages: e0148010
Publication
First Author: Sato Y
Year: 1998
Journal: J Biol Chem
Title: Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice.
Volume: 273
Issue: 43
Pages: 28470-7
Publication
First Author: Radwański PB
Year: 2015
Journal: Cardiovasc Res
Title: Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release.
Volume: 106
Issue: 1
Pages: 143-52
Publication
First Author: Liu N
Year: 2013
Journal: Circ Res
Title: Abnormal propagation of calcium waves and ultrastructural remodeling in recessive catecholaminergic polymorphic ventricular tachycardia.
Volume: 113
Issue: 2
Pages: 142-52
Publication  
First Author: Zhang JC
Year: 2018
Journal: Front Physiol
Title: Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2R33Q/R33Q Mutation Mice.
Volume: 9
Pages: 1447
Publication  
First Author: Blackwell DJ
Year: 2022
Journal: JCI Insight
Title: The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT.
Volume: 7
Issue: 3
Publication
First Author: Dirksen WP
Year: 2007
Journal: Cardiovasc Res
Title: A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice.
Volume: 75
Issue: 1
Pages: 69-78
GXD Expression      
Probe: MGI:3054389
Assay Type: Western blot
Annotation Date: 2004-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733128
Stage: TS28
Assay Id: MGI:3054401
Age: postnatal month 1
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3708283
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:3708328
Age: embryonic day 13.5
Image: 4
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3708283
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:3708328
Age: embryonic day 16.5
Image: 4
Specimen Label: E16.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:3758286
Age: embryonic day 7.5
Specimen Label: 7.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3758286
Age: embryonic day 8.5
Specimen Label: 8.5
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3758286
Age: embryonic day 10.5
Specimen Label: 10.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3758286
Age: embryonic day 12.5
Specimen Label: 12.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3758286
Age: embryonic day 14.5
Specimen Label: 14.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:3758286
Age: embryonic day 16.5
Specimen Label: 16.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3758286
Age: embryonic day 18.5
Specimen Label: 18.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3758290
Age: postnatal day 1
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3758290
Age: postnatal day 5
Specimen Label: 5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3758290
Age: postnatal day 20
Specimen Label: 20
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3758278
Assay Type: RT-PCR
Annotation Date: 2007-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3758290
Age: postnatal day 40
Specimen Label: 40
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3778416
Assay Type: RT-PCR
Annotation Date: 2008-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718523
Stage: TS23
Assay Id: MGI:3778508
Age: embryonic day 15.5
Image: 2
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3778416
Assay Type: RT-PCR
Annotation Date: 2008-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718523
Stage: TS23
Assay Id: MGI:3778508
Age: embryonic day 15.5
Image: 2
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: a2 HET
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: a2 HET
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: a2 KO
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Stage: TS26
Assay Id: MGI:3806082
Age: embryonic day 18.5
Specimen Label: a2 KO
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3806028
Assay Type: Western blot
Annotation Date: 2008-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770128
Stage: TS28
Assay Id: MGI:3806082
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5908421
Assay Type: RT-PCR
Annotation Date: 2017-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:5908442
Age: embryonic day 18.5
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5908421
Assay Type: RT-PCR
Annotation Date: 2017-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:5908442
Age: embryonic day 18.5
Image: S2
Specimen Label: tm1a/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5908421
Assay Type: RT-PCR
Annotation Date: 2017-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:5908442
Age: embryonic day 18.5
Image: S2
Specimen Label: tm1a/tm1a
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6285752
Assay Type: Western blot
Annotation Date: 2019-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6285906
Age: postnatal day 0
Specimen Label: P0 WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6285752
Assay Type: Western blot
Annotation Date: 2019-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6285906
Age: postnatal day 5
Specimen Label: P5 WT
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6285752
Assay Type: Western blot
Annotation Date: 2019-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6285906
Age: postnatal day 10
Specimen Label: P10 WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Absent
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Spleen
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Absent
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Lung
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Absent
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6317029
Assay Type: Northern blot
Annotation Date: 2019-07-10
Strength: Absent
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6317031
Age: postnatal week 8-12
Specimen Label: Skeletal Muscle
Detected: false
Specimen Num: 6