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Search results 1 to 100 out of 245 for Catsper1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: CATSPER (cationic channel of sperm) is a complex ion channel that mediates Ca2+ entry in sperm flagellum and is required for sperm hyperactivation and male fertility []. The CATSPER channel consists of four CatSper proteins (CatSper1-4) that form a tetramer surrounding a Ca(2+)-selective pore. In addition to the pore-forming proteins, the CATSPER channel contains auxiliary subunits [].All four CatSper proteins are predicted to contain a common coiled-coil protein-protein interaction domain in their C-terminal tail []and all four are required for male fertility and sperm cell hyperactivated motility []. The CatSper channel of human sperm is activated by progesterone [].This entry represents cation channel sperm-associated protein 1 (CatSper1) [].
Publication
First Author: Carlson AE
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm.
Volume: 100
Issue: 25
Pages: 14864-8
Publication
First Author: Qi H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.
Volume: 104
Issue: 4
Pages: 1219-23
Publication
First Author: Ren D
Year: 2001
Journal: Nature
Title: A sperm ion channel required for sperm motility and male fertility.
Volume: 413
Issue: 6856
Pages: 603-9
Publication  
First Author: Chung JJ
Year: 2011
Journal: Nat Commun
Title: A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa.
Volume: 2
Pages: 153
Protein
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
Publication
First Author: Jiménez-Badillo SE
Year: 2017
Journal: Sci Rep
Title: Catsper1 promoter is bidirectional and regulates the expression of a novel lncRNA.
Volume: 7
Issue: 1
Pages: 13351
Protein
Organism: Mus musculus/domesticus
Length: 686  
Fragment?: false
Publication
First Author: Mata-Rocha M
Year: 2014
Journal: FEBS Lett
Title: The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression.
Volume: 588
Issue: 18
Pages: 3352-60
Publication
First Author: Carlson AE
Year: 2005
Journal: J Biol Chem
Title: Identical phenotypes of CatSper1 and CatSper2 null sperm.
Volume: 280
Issue: 37
Pages: 32238-44
Publication
First Author: Wang H
Year: 2009
Journal: Biol Reprod
Title: A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.
Volume: 81
Issue: 3
Pages: 539-44
Publication
First Author: Zeng XH
Year: 2013
Journal: J Gen Physiol
Title: Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa.
Volume: 142
Issue: 3
Pages: 305-13
Publication
First Author: Marquez B
Year: 2007
Journal: Dev Biol
Title: Contributions of extracellular and intracellular Ca2+ to regulation of sperm motility: Release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm.
Volume: 303
Issue: 1
Pages: 214-21
Publication  
First Author: Lobley A
Year: 2003
Journal: Reprod Biol Endocrinol
Title: Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis.
Volume: 1
Pages: 53
Publication
First Author: Lishko PV
Year: 2011
Journal: Nature
Title: Progesterone activates the principal Ca2+ channel of human sperm.
Volume: 471
Issue: 7338
Pages: 387-91
Protein
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 496  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: true
Publication
First Author: Liu J
Year: 2007
Journal: J Biol Chem
Title: CatSperbeta, a novel transmembrane protein in the CatSper channel complex.
Volume: 282
Issue: 26
Pages: 18945-52
ncRNA Gene
Type: antisense_lncRNA_gene
Organism: mouse, laboratory
Publication
First Author: Xia J
Year: 2009
Journal: Biol Reprod
Title: Egg coat proteins activate calcium entry into mouse sperm via CATSPER channels.
Volume: 80
Issue: 6
Pages: 1092-8
Publication    
First Author: Ded L
Year: 2020
Journal: Elife
Title: 3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice.
Volume: 9
Publication
First Author: Navarrete FA
Year: 2015
Journal: J Cell Physiol
Title: Biphasic role of calcium in mouse sperm capacitation signaling pathways.
Volume: 230
Issue: 8
Pages: 1758-1769
Publication  
First Author: Navarrete FA
Year: 2016
Journal: Sci Rep
Title: Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.
Volume: 6
Pages: 33589
Publication  
First Author: Navarrete FA
Year: 2019
Journal: Front Cell Dev Biol
Title: Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies.
Volume: 7
Pages: 262
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Miki K
Year: 2013
Journal: Curr Biol
Title: Rheotaxis guides mammalian sperm.
Volume: 23
Issue: 6
Pages: 443-52
Publication
First Author: Orta G
Year: 2018
Journal: J Biol Chem
Title: CatSper channels are regulated by protein kinase A.
Volume: 293
Issue: 43
Pages: 16830-16841
Publication
First Author: Navarro B
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: KSper, a pH-sensitive K+ current that controls sperm membrane potential.
Volume: 104
Issue: 18
Pages: 7688-92
GXD Expression    
Probe: MGI:3835671
Assay Type: Western blot
Annotation Date: 2009-03-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3835769
Age: postnatal adult
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3835671
Assay Type: Western blot
Annotation Date: 2009-03-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3835769
Age: postnatal adult
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6147371
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:6147371
Age: postnatal adult
Specimen Label: Pachytene spermatocyte
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Stage: TS28
Assay Id: MGI:6147371
Age: postnatal adult
Specimen Label: Round spermatid
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Stage: TS28
Assay Id: MGI:6147371
Age: postnatal adult
Specimen Label: Elongated spermatid
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6147371
Age: embryonic day 11.0
Specimen Label: 11 day embryo
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-03-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6147371
Age: postnatal adult
Specimen Label: thymus
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Brain
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Heart
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Kidney
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Lung
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: S. muscle
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Sm. Int.
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Spleen
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6161582
Age: postnatal week 12
Image: 3
Specimen Label: Thymus
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Ovary
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Liver-F
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Heart-F
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Liver-M
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161604
Age: postnatal week 12
Image: 3
Specimen Label: Heart-M
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6161606
Age: embryonic day 11.5
Image: 3
Specimen Label: E11.5
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:6161606
Age: postnatal newborn
Image: 3
Specimen Label: n.b. testis
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:6161606
Age: postnatal newborn
Image: 3
Specimen Label: n.b. liver
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6161606
Age: postnatal newborn
Image: 3
Specimen Label: n.b. heart
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161609
Age: postnatal week 1
Image: 3
Specimen Label: Testis 1w
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161609
Age: postnatal week 1
Image: 3
Specimen Label: Liver 1w
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161609
Age: postnatal week 1
Image: 3
Specimen Label: Heart 1w
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161609
Age: postnatal week 12
Image: 3
Specimen Label: Adult testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161611
Age: postnatal week 12
Image: 3
Specimen Label: Adult testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161612
Age: postnatal week 12
Image: 3
Specimen Label: Adult testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161612
Age: postnatal week 3
Image: 3
Specimen Label: Testis 3w
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161612
Age: postnatal week 3
Image: 3
Specimen Label: Liver 3w
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161612
Age: postnatal week 3
Image: 3
Specimen Label: Heart 3w
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161611
Age: postnatal week 2
Image: 3
Specimen Label: Testis 2w
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161611
Age: postnatal week 2
Image: 3
Specimen Label: Liver 2w
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161611
Age: postnatal week 2
Image: 3
Specimen Label: Heart 2w
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161615
Age: postnatal week 12
Image: 3
Specimen Label: Adult testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161615
Age: postnatal week 4
Image: 3
Specimen Label: Testis 4w
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161615
Age: postnatal week 4
Image: 3
Specimen Label: Liver 4w
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6147370
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161615
Age: postnatal week 4
Image: 3
Specimen Label: Heart 4w
Detected: false
Specimen Num: 4