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Search results 1 to 100 out of 571 for Cbl

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Lee PS
Year: 1999
Journal: EMBO J
Title: The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation.
Volume: 18
Issue: 13
Pages: 3616-28
Publication
First Author: Miyake S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.
Volume: 95
Issue: 14
Pages: 7927-32
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Langdon WY
Year: 1995
Journal: Aust N Z J Med
Title: The cbl oncogene: a novel substrate of protein tyrosine kinases.
Volume: 25
Issue: 6
Pages: 859-64
Publication
First Author: Chiang YJ
Year: 2009
Journal: J Biol Chem
Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
Volume: 284
Issue: 7
Pages: 4429-38
Publication
First Author: Schmid FM
Year: 2018
Journal: J Cell Biol
Title: IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.
Volume: 217
Issue: 1
Pages: 151-161
Publication
First Author: Shao Y
Year: 2003
Journal: EMBO Rep
Title: Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase.
Volume: 4
Issue: 4
Pages: 425-31
Publication
First Author: Chiang J
Year: 2011
Journal: PLoS One
Title: Cbl enforces Vav1 dependence and a restricted pathway of T cell development.
Volume: 6
Issue: 4
Pages: e18542
Publication
First Author: Li X
Year: 2018
Journal: Immunity
Title: Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Volume: 48
Issue: 3
Pages: 530-541.e6
Publication
First Author: Kitaura Y
Year: 2007
Journal: Immunity
Title: Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.
Volume: 26
Issue: 5
Pages: 567-78
Publication
First Author: Blake TJ
Year: 1991
Journal: Oncogene
Title: The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.
Volume: 6
Issue: 4
Pages: 653-7
Publication
First Author: Gupte A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes.
Volume: 342
Issue: 3
Pages: 751-7
Publication  
First Author: Li X
Year: 2020
Journal: J Exp Med
Title: Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.
Volume: 217
Issue: 9
Publication
First Author: Mohapatra B
Year: 2017
Journal: Development
Title: An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Volume: 144
Issue: 6
Pages: 1072-1086
Publication
First Author: Caveggion E
Year: 2003
Journal: J Cell Physiol
Title: Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement.
Volume: 195
Issue: 2
Pages: 276-89
Publication
First Author: An W
Year: 2016
Journal: Oncotarget
Title: VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease.
Volume: 7
Issue: 37
Pages: 59006-59016
Publication
First Author: Latour S
Year: 1996
Journal: J Biol Chem
Title: Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases.
Volume: 271
Issue: 37
Pages: 22782-90
Publication
First Author: Fournel M
Year: 1996
Journal: J Exp Med
Title: Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.
Volume: 183
Issue: 1
Pages: 301-6
Publication
First Author: Hunter S
Year: 1999
Journal: J Biol Chem
Title: Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.
Volume: 274
Issue: 4
Pages: 2097-106
Publication
First Author: An W
Year: 2015
Journal: Oncotarget
Title: Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.
Volume: 6
Issue: 12
Pages: 10498-509
Publication
First Author: Huang F
Year: 2006
Journal: Immunity
Title: Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins.
Volume: 25
Issue: 4
Pages: 571-81
Publication
First Author: Wang L
Year: 2013
Journal: PLoS One
Title: Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Volume: 8
Issue: 2
Pages: e56666
Publication
First Author: Lv K
Year: 2017
Journal: Genes Dev
Title: CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.
Volume: 31
Issue: 10
Pages: 1007-1023
Protein
Organism: Mus musculus
Length: 83  
Fragment?: true
Publication
First Author: Meng F
Year: 1998
Journal: EMBO J
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Volume: 17
Issue: 15
Pages: 4391-403
Publication
First Author: Schnyder T
Year: 2011
Journal: Immunity
Title: B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
Volume: 34
Issue: 6
Pages: 905-18
Publication
First Author: Dale BM
Year: 2009
Journal: J Immunol
Title: Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.
Volume: 182
Issue: 9
Pages: 5654-62
Publication
First Author: Voisinne G
Year: 2016
Journal: Mol Syst Biol
Title: Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.
Volume: 12
Issue: 7
Pages: 876
Publication
First Author: Tezuka T
Year: 1996
Journal: J Exp Med
Title: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Volume: 183
Issue: 2
Pages: 675-80
Publication
First Author: Fasen K
Year: 2008
Journal: Traffic
Title: Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.
Volume: 9
Issue: 2
Pages: 251-66
Protein
Organism: Mus musculus
Length: 913  
Fragment?: false
Publication
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
Publication
First Author: Ollendorff V
Year: 1998
Journal: Int J Oncol
Title: A third human CBL gene is on chromosome 19.
Volume: 13
Issue: 6
Pages: 1159-61
Protein
Organism: Mus musculus
Length: 79  
Fragment?: true
Protein
Organism: Mus musculus
Length: 78  
Fragment?: true
Publication
First Author: Scanlon V
Year: 2015
Journal: PLoS One
Title: Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
Volume: 10
Issue: 9
Pages: e0138194
Publication  
First Author: Yu J
Year: 2019
Journal: Bone
Title: Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts.
Volume: 127
Pages: 376-385
Publication
First Author: Nakata Y
Year: 2017
Journal: Blood
Title: Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Volume: 129
Issue: 15
Pages: 2148-2160
Publication
First Author: Adapala NS
Year: 2010
Journal: J Biol Chem
Title: The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.
Volume: 285
Issue: 47
Pages: 36745-58
Publication
First Author: Doherty L
Year: 2019
Journal: PLoS One
Title: A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing.
Volume: 14
Issue: 10
Pages: e0223846
Publication  
First Author: Adapala NS
Year: 2014
Journal: Bone
Title: Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Volume: 67
Pages: 1-9
Publication  
First Author: Scanlon V
Year: 2017
Journal: Bone
Title: Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.
Volume: 95
Pages: 124-135
Publication
First Author: Feng L
Year: 2011
Journal: Cell Biochem Funct
Title: SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex.
Volume: 29
Issue: 7
Pages: 589-96
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Rattus norvegicus
Protein
Organism: Mus musculus
Length: 51  
Fragment?: true
Publication
First Author: Adapala NS
Year: 2014
Journal: J Cell Biochem
Title: Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.
Volume: 115
Issue: 7
Pages: 1277-89
Publication
First Author: Ribon V
Year: 1998
Journal: Mol Cell Biol
Title: A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.
Volume: 18
Issue: 2
Pages: 872-9
Publication
First Author: Molero JC
Year: 2006
Journal: Diabetes
Title: Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action.
Volume: 55
Issue: 12
Pages: 3411-7
Publication
First Author: Buitrago L
Year: 2011
Journal: Blood
Title: Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.
Volume: 118
Issue: 20
Pages: 5631-40
Publication
First Author: Chen W
Year: 2013
Journal: Cell
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
Volume: 152
Issue: 3
Pages: 467-78
Publication
First Author: Thien CB
Year: 2010
Journal: J Biol Chem
Title: c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.
Volume: 285
Issue: 14
Pages: 10969-81
Publication
First Author: Shao Y
Year: 2004
Journal: J Biol Chem
Title: Differential regulation of the B cell receptor-mediated signaling by the E3 ubiquitin ligase Cbl.
Volume: 279
Issue: 42
Pages: 43646-53
Publication
First Author: Naramura M
Year: 2002
Journal: Nat Immunol
Title: c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.
Volume: 3
Issue: 12
Pages: 1192-9
Publication
First Author: Leiser D
Year: 2014
Journal: FEBS Lett
Title: Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation.
Volume: 588
Issue: 5
Pages: 653-8
Publication
First Author: El Chami N
Year: 2005
Journal: J Cell Biol
Title: Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl.
Volume: 171
Issue: 4
Pages: 651-61
Publication
First Author: Thien CB
Year: 2003
Journal: J Exp Med
Title: A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase.
Volume: 197
Issue: 4
Pages: 503-13
Publication
First Author: Polzer H
Year: 2013
Journal: Exp Hematol
Title: Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases.
Volume: 41
Issue: 3
Pages: 271-80.e4
Publication
First Author: Ota Y
Year: 1997
Journal: Science
Title: The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase.
Volume: 276
Issue: 5311
Pages: 418-20
Publication
First Author: Murphy MA
Year: 1998
Journal: Mol Cell Biol
Title: Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice.
Volume: 18
Issue: 8
Pages: 4872-82
Publication
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
Publication
First Author: Naramura M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Altered thymic positive selection and intracellular signals in Cbl-deficient mice.
Volume: 95
Issue: 26
Pages: 15547-52
Publication
First Author: Naramura M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.
Volume: 107
Issue: 37
Pages: 16274-9
Publication
First Author: Goetz B
Year: 2016
Journal: Oncotarget
Title: A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.
Volume: 7
Issue: 32
Pages: 51107-51123
Publication
First Author: Daniels SR
Year: 2019
Journal: PLoS One
Title: Loss of function Cbl-c mutations in solid tumors.
Volume: 14
Issue: 7
Pages: e0219143
Publication
First Author: Kim JH
Year: 2010
Journal: J Biol Chem
Title: Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.
Volume: 285
Issue: 8
Pages: 5224-31
Publication
First Author: Baumann CA
Year: 2000
Journal: Nature
Title: CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Volume: 407
Issue: 6801
Pages: 202-7
Publication
First Author: Chiang YJ
Year: 2015
Journal: Int Immunol
Title: Regulation of T cell development by c-Cbl: essential role of Lck.
Volume: 27
Issue: 5
Pages: 245-51
Publication
First Author: Zhang J
Year: 2004
Journal: J Immunol
Title: Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
Volume: 173
Issue: 3
Pages: 1811-8
Publication
First Author: Davidson D
Year: 2016
Journal: Cell Rep
Title: The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.
Volume: 17
Issue: 10
Pages: 2776-2788
Publication
First Author: Roman-Trufero M
Year: 2020
Journal: Mol Biol Evol
Title: Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.
Volume: 37
Issue: 7
Pages: 1986-2001
Publication
First Author: Miyazaki T
Year: 2004
Journal: J Biol Chem
Title: Src kinase activity is essential for osteoclast function.
Volume: 279
Issue: 17
Pages: 17660-6
Publication
First Author: Purev E
Year: 2009
Journal: Mol Biol Cell
Title: c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes.
Volume: 20
Issue: 18
Pages: 4021-30
Publication
First Author: Crowley MR
Year: 2005
Journal: Dev Biol
Title: TGF-beta, c-Cbl, and PDGFR-alpha the in mammary stroma.
Volume: 279
Issue: 1
Pages: 58-72
Publication
First Author: Ojaniemi M
Year: 1997
Journal: J Biol Chem
Title: The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.
Volume: 272
Issue: 6
Pages: 3780-7
Publication
First Author: Miura A
Year: 2004
Journal: Biochemistry
Title: Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
Volume: 43
Issue: 49
Pages: 15503-9
Publication
First Author: Fecchi K
Year: 2006
Journal: FASEB J
Title: Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.
Volume: 20
Issue: 6
Pages: 705-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus