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Search results 1 to 100 out of 144 for Cbx4

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0.086s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Polycomb group (PcG) proteins were first identified in Drosophila but mammalian homologs have been identified. They interact with each other to form multimeric, chromatin-associated protein complexes. The human orthologs of the Drosophila PcG proteins are CBX2, CBX4, CBX6, CBX7 and CBX8, which exhibit distinct nuclear localisations and they contribute differently to transcriptional repression. They have been described as regulators of homeotic gene expression. It has been demonstrated that these proteins maintain the repressed state of these genes, involved in development, signalling or cancer []. PcG complexes can be recruited to DNA by interactions with specific DNA binding proteins [].Sumoylation is a reversible conjugation process similar to ubiquitination, in which proteins involved in a wide range of processes are modified, such as DNA repair, chromosome segregation and gene expression. It implies an activating enzyme (E1), a conjugating enzyme (E2), and a ligase (E3) As well as in the ubiquitination process, the E3 ligase determines substrate specificity. Polycomb protein Pc2, also known as CBX4, is a SUMO (small ubiquitin-related modifier) ligase E3. DNA damage activates CBX4 which sumoylates the heterogeneous nuclear ribonucleoprotein K (hnRNP K), a p53 cofactor required for transcriptional regulation of p53 target genes [].This entry includes de E3 SUMO-protein ligase CBX4 (also known as Pc2).
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
Publication
First Author: Kagey MH
Year: 2003
Journal: Cell
Title: The polycomb protein Pc2 is a SUMO E3.
Volume: 113
Issue: 1
Pages: 127-37
Protein
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
Publication
First Author: Pelisch F
Year: 2012
Journal: J Biol Chem
Title: DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation.
Volume: 287
Issue: 36
Pages: 30789-99
Publication
First Author: Chen Q
Year: 2018
Journal: Cell Rep
Title: Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis.
Volume: 22
Issue: 11
Pages: 2860-2872
Publication
First Author: Li B
Year: 2007
Journal: Biochem J
Title: Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a.
Volume: 405
Issue: 2
Pages: 369-78
Publication
First Author: Melo GA
Year: 2023
Journal: J Immunol
Title: Cutting Edge: Polycomb Repressive Complex 1 Subunit Cbx4 Positively Regulates Effector Responses in CD8 T Cells.
Volume: 211
Issue: 5
Pages: 721-726
Publication
First Author: Vandamme J
Year: 2011
Journal: Mol Cell Proteomics
Title: Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.
Volume: 10
Issue: 4
Pages: M110.002642
Publication
First Author: Liu B
Year: 2013
Journal: Development
Title: Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Volume: 140
Issue: 4
Pages: 780-8
Publication
First Author: Mardaryev AN
Year: 2016
Journal: J Cell Biol
Title: Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.
Volume: 212
Issue: 1
Pages: 77-89
Publication  
First Author: Jiang N
Year: 2020
Journal: EBioMedicine
Title: CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma.
Volume: 53
Pages: 102692
Publication
First Author: Alkema MJ
Year: 1997
Journal: J Mol Biol
Title: MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.
Volume: 273
Issue: 5
Pages: 993-1003
Publication
First Author: Bernstein E
Year: 2006
Journal: Mol Cell Biol
Title: Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.
Volume: 26
Issue: 7
Pages: 2560-9
Publication
First Author: Ning B
Year: 2017
Journal: Nat Commun
Title: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Volume: 8
Issue: 1
Pages: 349
Protein
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3784255
Assay Type: RT-PCR
Annotation Date: 2008-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654814
Stage: TS14
Assay Id: MGI:3784529
Age: embryonic day 9.0
Specimen Label: 16-20s
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3784255
Assay Type: RT-PCR
Annotation Date: 2008-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654815
Stage: TS15
Assay Id: MGI:3784529
Age: embryonic day 9.5
Specimen Label: 26-30s
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3688566
Age: embryonic day 13.5
Note: Expression is in the hippocampus.
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459943
Specimen Label: TCP_2459943
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459944
Specimen Label: TCP_2459944
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459930
Specimen Label: TCP_2459930
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459931
Specimen Label: TCP_2459931
Detected: true
Specimen Num: 18
GXD Expression
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 7A
Note: Expression is in the superior and inferior colliculi.
Specimen Label: 7A
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 5E
Note: Higher magnification was shown in the inset.
Specimen Label: 5E
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3688566
Age: embryonic day 13.5
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 4D
Specimen Label: 4D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 7A
Note: Expression is in the purkinje cell layer (more strongly) and the external granule cell layer and is absent in the molecular layer.
Specimen Label: 7A
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 4D
Specimen Label: 4D
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3784469
Assay Type: RNA in situ
Annotation Date: 2008-05-09
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1672815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3784470
Age: embryonic day 9.5
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 5E
Note: Expression is in CA1-3. Higher magnification was shown in the inset.
Specimen Label: 5E
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459941
Specimen Label: TCP_2459941
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459942
Specimen Label: TCP_2459942
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459934
Specimen Label: TCP_2459934
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459955
Specimen Label: TCP_2459955
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459956
Specimen Label: TCP_2459956
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3784469
Assay Type: RNA in situ
Annotation Date: 2008-05-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3784470
Age: embryonic day 10.5
Image: 6I
Specimen Label: 6I
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459951
Specimen Label: TCP_2459951
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459952
Specimen Label: TCP_2459952
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459935
Specimen Label: TCP_2459935
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459936
Specimen Label: TCP_2459936
Detected: true
Specimen Num: 23
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459953
Specimen Label: TCP_2459953
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459954
Specimen Label: TCP_2459954
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3688566
Age: embryonic day 13.5
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5300343
Assay Type: RNA in situ
Annotation Date: 2012-01-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3599825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5300344
Age: embryonic day 17.5
Image: 4c left
Specimen Label: 4c left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5300343
Assay Type: RNA in situ
Annotation Date: 2012-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5300344
Age: postnatal
Image: 4c right
Note: A marked induction beginning at P5-P10.
Specimen Label: 4c right
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5300343
Assay Type: RNA in situ
Annotation Date: 2012-01-03
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5300344
Age: postnatal adult
Image: 5a lower left
Specimen Label: 5a lower left
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5300343
Assay Type: RNA in situ
Annotation Date: 2012-01-03
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5300344
Age: postnatal adult
Image: 5a lower right
Note: 2-3-fold diminished expression compared with littermate control.
Specimen Label: 5a lower right
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3688565
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688566
Age: embryonic day 18.5
Image: 6D
Note: Higher magnification was shown in the inset. Expression is in the differentiated mitral layer and is weak in the ventricular zone and granular layer.
Specimen Label: 6D
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459937
Specimen Label: TCP_2459937
Detected: true
Specimen Num: 24
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459938
Specimen Label: TCP_2459938
Detected: true
Specimen Num: 25
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459939
Specimen Label: TCP_2459939
Detected: true
Specimen Num: 26
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459940
Specimen Label: TCP_2459940
Detected: true
Specimen Num: 27
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459945
Specimen Label: TCP_2459945
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459946
Specimen Label: TCP_2459946
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459947
Specimen Label: TCP_2459947
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459948
Specimen Label: TCP_2459948
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459932
Specimen Label: TCP_2459932
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459933
Specimen Label: TCP_2459933
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459949
Specimen Label: TCP_2459949
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691246
Age: postnatal adult
Image: TCP_2459950
Specimen Label: TCP_2459950
Detected: true
Specimen Num: 10
Publication
First Author: Hemenway CS
Year: 2000
Journal: Gene
Title: Identification and analysis of a third mouse Polycomb gene, MPc3.
Volume: 242
Issue: 1-2
Pages: 31-40
Publication
First Author: Yang SH
Year: 2010
Journal: Mol Cell Biol
Title: The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif.
Volume: 30
Issue: 9
Pages: 2193-205
Publication
First Author: Vogel T
Year: 2006
Journal: Dev Dyn
Title: Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes.
Volume: 235
Issue: 9
Pages: 2574-85
Publication
First Author: Gur I
Year: 2014
Journal: PLoS One
Title: Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.
Volume: 9
Issue: 6
Pages: e99503
Publication
First Author: Puschendorf M
Year: 2008
Journal: Nat Genet
Title: PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.
Volume: 40
Issue: 4
Pages: 411-20
Publication
First Author: Voncken JW
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.
Volume: 100
Issue: 5
Pages: 2468-73
Publication
First Author: Cho KW
Year: 2023
Journal: Circulation
Title: Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
Volume: 147
Issue: 24
Pages: 1823-1842