Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Polycomb group (PcG) proteins were first identified in Drosophila but mammalian homologs have been identified. They interact with each other to form multimeric, chromatin-associated protein complexes. The human orthologs of the Drosophila PcG proteins are CBX2, CBX4, CBX6, CBX7 and CBX8, which exhibit distinct nuclear localisations and they contribute differently to transcriptional repression. They have been described as regulators of homeotic gene expression. It has been demonstrated that these proteins maintain the repressed state of these genes, involved in development, signalling or cancer []. PcG complexes can be recruited to DNA by interactions with specific DNA binding proteins [].Sumoylation is a reversible conjugation process similar to ubiquitination, in which proteins involved in a wide range of processes are modified, such as DNA repair, chromosome segregation and gene expression. It implies an activating enzyme (E1), a conjugating enzyme (E2), and a ligase (E3) As well as in the ubiquitination process, the E3 ligase determines substrate specificity. Polycomb protein Pc2, also known as CBX4, is a SUMO (small ubiquitin-related modifier) ligase E3. DNA damage activates CBX4 which sumoylates the heterogeneous nuclear ribonucleoprotein K (hnRNP K), a p53 cofactor required for transcriptional regulation of p53 target genes [].This entry includes de E3 SUMO-protein ligase CBX4 (also known as Pc2). |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
551
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
258
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
302
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
61
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kagey MH |
Year: |
2003 |
Journal: |
Cell |
Title: |
The polycomb protein Pc2 is a SUMO E3. |
Volume: |
113 |
Issue: |
1 |
Pages: |
127-37 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
117
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Pelisch F |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation. |
Volume: |
287 |
Issue: |
36 |
Pages: |
30789-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Q |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. |
Volume: |
22 |
Issue: |
11 |
Pages: |
2860-2872 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2007 |
Journal: |
Biochem J |
Title: |
Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a. |
Volume: |
405 |
Issue: |
2 |
Pages: |
369-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vandamme J |
Year: |
2011 |
Journal: |
Mol Cell Proteomics |
Title: |
Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells. |
Volume: |
10 |
Issue: |
4 |
Pages: |
M110.002642 |
|
•
•
•
•
•
|
Publication |
First Author: |
Melo GA |
Year: |
2023 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Polycomb Repressive Complex 1 Subunit Cbx4 Positively Regulates Effector Responses in CD8 T Cells. |
Volume: |
211 |
Issue: |
5 |
Pages: |
721-726 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu B |
Year: |
2013 |
Journal: |
Development |
Title: |
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. |
Volume: |
140 |
Issue: |
4 |
Pages: |
780-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mardaryev AN |
Year: |
2016 |
Journal: |
J Cell Biol |
Title: |
Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. |
Volume: |
212 |
Issue: |
1 |
Pages: |
77-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang N |
Year: |
2020 |
Journal: |
EBioMedicine |
Title: |
CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma. |
Volume: |
53 |
|
Pages: |
102692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alkema MJ |
Year: |
1997 |
Journal: |
J Mol Biol |
Title: |
MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex. |
Volume: |
273 |
Issue: |
5 |
Pages: |
993-1003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernstein E |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. |
Volume: |
26 |
Issue: |
7 |
Pages: |
2560-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ning B |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components. |
Volume: |
8 |
Issue: |
1 |
Pages: |
349 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
485
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784255 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-05-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654814 |
|
Stage: |
TS14 |
Assay Id: |
MGI:3784529 |
Age: |
embryonic day 9.0 |
|
|
Specimen Label: |
16-20s |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784255 |
Assay Type: |
RT-PCR |
Annotation Date: |
2008-05-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654815 |
|
Stage: |
TS15 |
Assay Id: |
MGI:3784529 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
26-30s |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689521 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 13.5 |
|
Note: |
Expression is in the hippocampus. |
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459943 |
|
Specimen Label: |
TCP_2459943 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459944 |
|
Specimen Label: |
TCP_2459944 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459930 |
|
Specimen Label: |
TCP_2459930 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459931 |
|
Specimen Label: |
TCP_2459931 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697426 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
7A |
Note: |
Expression is in the superior and inferior colliculi. |
Specimen Label: |
7A |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1903726 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
5E |
Note: |
Higher magnification was shown in the inset. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271126 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
4D |
|
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427150 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621773 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427150 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-22 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7711538 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary Table 3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778726 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
7A |
Note: |
Expression is in the purkinje cell layer (more strongly) and the external granule cell layer and is absent in the molecular layer. |
Specimen Label: |
7A |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
4D |
|
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784469 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-09 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672815 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:3784470 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
5E |
Note: |
Expression is in CA1-3. Higher magnification was shown in the inset. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1842628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459941 |
|
Specimen Label: |
TCP_2459941 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1842628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459942 |
|
Specimen Label: |
TCP_2459942 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1684628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459934 |
|
Specimen Label: |
TCP_2459934 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1718528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459955 |
|
Specimen Label: |
TCP_2459955 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1718528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459956 |
|
Specimen Label: |
TCP_2459956 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784469 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-09 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3784470 |
Age: |
embryonic day 10.5 |
Image: |
6I |
|
Specimen Label: |
6I |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1750328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459951 |
|
Specimen Label: |
TCP_2459951 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1750328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459952 |
|
Specimen Label: |
TCP_2459952 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1750328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459935 |
|
Specimen Label: |
TCP_2459935 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1750328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459936 |
|
Specimen Label: |
TCP_2459936 |
Detected: |
true |
Specimen Num: |
23 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459953 |
|
Specimen Label: |
TCP_2459953 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459954 |
|
Specimen Label: |
TCP_2459954 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754721 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427150 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621773 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427150 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7711538 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary Table 3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300343 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-01-03 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599825 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5300344 |
Age: |
embryonic day 17.5 |
Image: |
4c left |
|
Specimen Label: |
4c left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300343 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-01-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5300344 |
Age: |
postnatal |
Image: |
4c right |
Note: |
A marked induction beginning at P5-P10. |
Specimen Label: |
4c right |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300343 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-01-03 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3599828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5300344 |
Age: |
postnatal adult |
Image: |
5a lower left |
|
Specimen Label: |
5a lower left |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300343 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-01-03 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3599828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5300344 |
Age: |
postnatal adult |
Image: |
5a lower right |
Note: |
2-3-fold diminished expression compared with littermate control. |
Specimen Label: |
5a lower right |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3688565 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-11-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280926 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:3688566 |
Age: |
embryonic day 18.5 |
Image: |
6D |
Note: |
Higher magnification was shown in the inset. Expression is in the differentiated mitral layer and is weak in the ventricular zone and granular layer. |
Specimen Label: |
6D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459937 |
|
Specimen Label: |
TCP_2459937 |
Detected: |
true |
Specimen Num: |
24 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1752528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459938 |
|
Specimen Label: |
TCP_2459938 |
Detected: |
true |
Specimen Num: |
25 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459939 |
|
Specimen Label: |
TCP_2459939 |
Detected: |
true |
Specimen Num: |
26 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459940 |
|
Specimen Label: |
TCP_2459940 |
Detected: |
true |
Specimen Num: |
27 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459945 |
|
Specimen Label: |
TCP_2459945 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459946 |
|
Specimen Label: |
TCP_2459946 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459947 |
|
Specimen Label: |
TCP_2459947 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459948 |
|
Specimen Label: |
TCP_2459948 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459932 |
|
Specimen Label: |
TCP_2459932 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459933 |
|
Specimen Label: |
TCP_2459933 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459949 |
|
Specimen Label: |
TCP_2459949 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691246 |
Age: |
postnatal adult |
Image: |
TCP_2459950 |
|
Specimen Label: |
TCP_2459950 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hemenway CS |
Year: |
2000 |
Journal: |
Gene |
Title: |
Identification and analysis of a third mouse Polycomb gene, MPc3. |
Volume: |
242 |
Issue: |
1-2 |
Pages: |
31-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang SH |
Year: |
2010 |
Journal: |
Mol Cell Biol |
Title: |
The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif. |
Volume: |
30 |
Issue: |
9 |
Pages: |
2193-205 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vogel T |
Year: |
2006 |
Journal: |
Dev Dyn |
Title: |
Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes. |
Volume: |
235 |
Issue: |
9 |
Pages: |
2574-85 |
|
•
•
•
•
•
|