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Search results 1 to 100 out of 147 for Cbx7

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Type Details Score
Gene
23492 | CBX7
Type: gene
Organism: human
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Gene
525770 | CBX7
Type: gene
Organism: cattle
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Gene
703056 | CBX7
Type: gene
Organism: macaque, rhesus
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Gene
101752246 | CBX7
Type: gene
Organism: chicken
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Gene
448638 | cbx7
Type: gene
Organism: frog, western clawed
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Gene
362962 | Cbx7
Type: gene
Organism: rat
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Gene
481247 | CBX7
Type: gene
Organism: dog, domestic
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Gene
458843 | CBX7
Type: gene
Organism: chimpanzee
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Protein Domain
IPR043000 | CBX7
Type: Family
Description: PcG proteins form large multiprotein complexes (PcG bodies) which are involved in the stable repression of genes involved in development, signaling or cancer via chromatin-based epigenetic modifications. Mammalian PRC1 includes canonical (cPRC1) and non-canonical complexes; cPRC1, contains four core subunits including one CBX protein (CBX2, CBX4, and CBX6-CBX8) that binds H3K27me3. CBX family members have different affinity for H3K27me3, with CBX7 having the highest binding capability [, ].This entry represents CBX7 []. In pluripotent cells, CBX7 is the main PRC1-associated Cbx protein and plays an important role in the maintenance of pluripotency [].
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Protein Coding Gene
MGI:1196439 | Cbx7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32415167 | J:291596
First Author: Cho KW
Year: 2020
Journal: Sci Rep
Title: Mammalian CBX7 isoforms p36 and p22 exhibit differential responses to serum, varying functions for proliferation, and distinct subcellular localization.
Volume: 10
Issue: 1
Pages: 8061
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Protein
A0A6M8AZW7
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Publication
14647293 | J:90489
First Author: Gil J
Year: 2004
Journal: Nat Cell Biol
Title: Polycomb CBX7 has a unifying role in cellular lifespan.
Volume: 6
Issue: 1
Pages: 67-72
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Publication
22214847 | J:184383
First Author: Forzati F
Year: 2012
Journal: J Clin Invest
Title: CBX7 is a tumor suppressor in mice and humans.
Volume: 122
Issue: 2
Pages: 612-23
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Publication
17374722 | J:120126
First Author: Scott CL
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role of the chromobox protein CBX7 in lymphomagenesis.
Volume: 104
Issue: 13
Pages: 5389-94
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Publication
25190058 | J:213773
First Author: Forzati F
Year: 2014
Journal: Biol Open
Title: CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation.
Volume: 3
Issue: 9
Pages: 871-9
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Publication
27271093 | J:318895
First Author: Zhou Z
Year: 2016
Journal: J Mol Histol
Title: CBX7 deficiency plays a positive role in dentin and alveolar bone development.
Volume: 47
Issue: 4
Pages: 401-11
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Publication
30238429 | J:318896
First Author: Jiang F
Year: 2019
Journal: J Bone Miner Metab
Title: Effect of CBX7 deficiency on the socket healing after tooth extractions.
Volume: 37
Issue: 4
Pages: 584-593
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Publication
23273917 | J:196328
First Author: Morey L
Year: 2013
Journal: Cell Rep
Title: RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells.
Volume: 3
Issue: 1
Pages: 60-9
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Publication
37158107 | J:338403
First Author: Cho KW
Year: 2023
Journal: Circulation
Title: Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
Volume: 147
Issue: 24
Pages: 1823-1842
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Publication
22226355 | -
First Author: Morey L
Year: 2012
Journal: Cell Stem Cell
Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.
Volume: 10
Issue: 1
Pages: 47-62
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Protein
D3YYK4
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
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Publication
21047797 | -
First Author: Kaustov L
Year: 2011
Journal: J Biol Chem
Title: Recognition and specificity determinants of the human cbx chromodomains.
Volume: 286
Issue: 1
Pages: 521-9
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Publication
24793759 | -
First Author: Ma RG
Year: 2014
Journal: J Zhejiang Univ Sci B
Title: Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins.
Volume: 15
Issue: 5
Pages: 412-28
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Publication
21282530 | -
First Author: Vandamme J
Year: 2011
Journal: Mol Cell Proteomics
Title: Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.
Volume: 10
Issue: 4
Pages: M110.002642
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Protein
F6WJA6
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
H3BK45
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
Q8VDS3
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
F8WHN2
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Publication
24194518 | J:207230
First Author: Wu HA
Year: 2013
Journal: J Biol Chem
Title: Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.
Volume: 288
Issue: 51
Pages: 36398-408
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Publication
23502315 | J:197636
First Author: Klauke K
Year: 2013
Journal: Nat Cell Biol
Title: Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.
Volume: 15
Issue: 4
Pages: 353-62
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Publication
19636380 | J:151469
First Author: Maertens GN
Year: 2009
Journal: PLoS One
Title: Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.
Volume: 4
Issue: 7
Pages: e6380
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Publication
16537902 | J:106925
First Author: Bernstein E
Year: 2006
Journal: Mol Cell Biol
Title: Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.
Volume: 26
Issue: 7
Pages: 2560-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0020030 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022057 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1196439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021349 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021900 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020032 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020928 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
20543829 | J:245293
First Author: El Messaoudi-Aubert S
Year: 2010
Journal: Nat Struct Mol Biol
Title: Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.
Volume: 17
Issue: 7
Pages: 862-8
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3688569
Age: embryonic day 13.5
Note: Expression is in the hippocampus.
Specimen Label: Not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 7B
Note: Expression is in the superior and inferior colliculi.
Specimen Label: 7B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 5F
Note: Higher magnification was shown in the inset.
Specimen Label: 5F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3688569
Age: postnatal adult
Image: 9E
Specimen Label: 9E
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3688569
Age: embryonic day 13.5
Specimen Label: Not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 4E
Specimen Label: 4E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3688569
Age: postnatal adult
Image: 9H
Specimen Label: 9H
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3688569
Age: postnatal adult
Image: 9B
Specimen Label: 9B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 7B
Note: Expression is in the purkinje cell layer (more strongly) and the external granule cell layer and is absent in the molecular layer.
Specimen Label: 7B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 4E
Specimen Label: 4E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 5F
Note: Expression is in CA1-3. Higher magnification was shown in the inset.
Specimen Label: 5F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3688569
Age: postnatal adult
Image: 9B
Specimen Label: 9B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3688569
Age: postnatal adult
Image: 9B
Specimen Label: 9B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3688569
Age: embryonic day 13.5
Specimen Label: Not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1901967
Assay Type: RNA in situ
Annotation Date: 2006-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688569
Age: embryonic day 18.5
Image: 6E
Note: Higher magnification was shown in the inset. Expression is in the differentiated mitral layer and is weak in the ventricular zone and granular layer.
Specimen Label: 6E
Detected: true
Specimen Num: 4
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Publication
24687849 | J:215355
First Author: Cheng B
Year: 2014
Journal: Mol Cell Biol
Title: KAP1 represses differentiation-inducible genes in embryonic stem cells through cooperative binding with PRC1 and derepresses pluripotency-associated genes.
Volume: 34
Issue: 11
Pages: 2075-91
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Publication
28839133 | J:338222
First Author: Ning B
Year: 2017
Journal: Nat Commun
Title: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Volume: 8
Issue: 1
Pages: 349
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Publication
23395003 | J:197096
First Author: Wu X
Year: 2013
Journal: Mol Cell
Title: Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation.
Volume: 49
Issue: 6
Pages: 1134-46
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Publication
24034696 | J:203428
First Author: Frangini A
Year: 2013
Journal: Mol Cell
Title: The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes.
Volume: 51
Issue: 5
Pages: 647-61
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Publication
22325148 | J:186106
First Author: Tavares L
Year: 2012
Journal: Cell
Title: RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.
Volume: 148
Issue: 4
Pages: 664-78
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Publication
22056776 | J:180185
First Author: Lynch MD
Year: 2012
Journal: EMBO J
Title: An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.
Volume: 31
Issue: 2
Pages: 317-29
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Publication
16786585 | J:111614
First Author: Vogel T
Year: 2006
Journal: Dev Dyn
Title: Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes.
Volume: 235
Issue: 9
Pages: 2574-85
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Publication
28111200 | J:251488
First Author: Li H
Year: 2017
Journal: Cell Stem Cell
Title: RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions.
Volume: 20
Issue: 4
Pages: 462-477.e6
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Publication
23870131 | J:200082
First Author: White JK
Year: 2013
Journal: Cell
Title: Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
Volume: 154
Issue: 2
Pages: 452-64
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Publication
18311137 | J:134477
First Author: Puschendorf M
Year: 2008
Journal: Nat Genet
Title: PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.
Volume: 40
Issue: 4
Pages: 411-20
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Publication
24721909 | J:209956
 
First Author: Liakath-Ali K
Year: 2014
Journal: Nat Commun
Title: Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Volume: 5
Pages: 3540
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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