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Search results 1 to 100 out of 317 for Ccm2

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Harel L
Year: 2009
Journal: Neuron
Title: CCM2 mediates death signaling by the TrkA receptor tyrosine kinase.
Volume: 63
Issue: 5
Pages: 585-91
Publication
First Author: Yaba A
Year: 2015
Journal: J Assist Reprod Genet
Title: Expression of CCM2 and CCM3 during mouse gonadogenesis.
Volume: 32
Issue: 10
Pages: 1497-507
Publication
First Author: Plummer NW
Year: 2006
Journal: Mamm Genome
Title: Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations.
Volume: 17
Issue: 2
Pages: 119-28
Publication
First Author: Boulday G
Year: 2011
Journal: J Exp Med
Title: Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice.
Volume: 208
Issue: 9
Pages: 1835-47
Publication
First Author: Zawistowski JS
Year: 2005
Journal: Hum Mol Genet
Title: CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.
Volume: 14
Issue: 17
Pages: 2521-31
Publication
First Author: Boulday G
Year: 2009
Journal: Dis Model Mech
Title: Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations.
Volume: 2
Issue: 3-4
Pages: 168-77
Publication
First Author: Voss K
Year: 2007
Journal: Neurogenetics
Title: CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations.
Volume: 8
Issue: 4
Pages: 249-56
Publication
First Author: Cunningham K
Year: 2011
Journal: Hum Mol Genet
Title: Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations.
Volume: 20
Issue: 16
Pages: 3198-206
Publication  
First Author: Fong B
Year: 2007
Journal: BMC Dev Biol
Title: Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation.
Volume: 7
Pages: 2
Publication
First Author: Li J
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways.
Volume: 1865
Issue: 11
Pages: 165519
Publication
First Author: Cardoso C
Year: 2020
Journal: Stroke
Title: Novel Chronic Mouse Model of Cerebral Cavernous Malformations.
Volume: 51
Issue: 4
Pages: 1272-1278
Publication
First Author: Whitehead KJ
Year: 2009
Journal: Nat Med
Title: The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases.
Volume: 15
Issue: 2
Pages: 177-84
Publication
First Author: Stockton RA
Year: 2010
Journal: J Exp Med
Title: Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
Volume: 207
Issue: 4
Pages: 881-96
Publication
First Author: Zhou Z
Year: 2015
Journal: Dev Cell
Title: The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
Volume: 32
Issue: 2
Pages: 168-80
Publication  
First Author: Fisher OS
Year: 2015
Journal: Nat Commun
Title: Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
Volume: 6
Pages: 7937
Publication
First Author: Choi JP
Year: 2016
Journal: PLoS One
Title: Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice.
Volume: 11
Issue: 8
Pages: e0160833
Publication
First Author: Zheng X
Year: 2012
Journal: Dev Cell
Title: Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth.
Volume: 23
Issue: 2
Pages: 342-55
Publication
First Author: Li J
Year: 2020
Journal: PLoS Biol
Title: Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.
Volume: 18
Issue: 6
Pages: e3000734
Publication
First Author: Petit N
Year: 2006
Journal: Gene Expr Patterns
Title: Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development.
Volume: 6
Issue: 5
Pages: 495-503
Publication
First Author: McDonald DA
Year: 2011
Journal: Hum Mol Genet
Title: A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Volume: 20
Issue: 2
Pages: 211-22
Publication
First Author: Zhou Z
Year: 2016
Journal: Nature
Title: Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
Volume: 532
Issue: 7597
Pages: 122-6
Publication
First Author: Chan AC
Year: 2011
Journal: J Clin Invest
Title: Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.
Volume: 121
Issue: 5
Pages: 1871-81
Publication
First Author: Kleaveland B
Year: 2009
Journal: Nat Med
Title: Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.
Volume: 15
Issue: 2
Pages: 169-76
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Grdseloff N
Year: 2023
Journal: Sci Rep
Title: Impaired retinoic acid signaling in cerebral cavernous malformations.
Volume: 13
Issue: 1
Pages: 5572
Publication
First Author: Gibson CC
Year: 2015
Journal: Circulation
Title: Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
Volume: 131
Issue: 3
Pages: 289-99
Publication      
First Author: Whitehead K
Year: 2008
Journal: MGI Direct Data Submission
Title: The Cerebral Cavernous Malformation signaling pathway promotes vascular intergrity via Rho GTPases
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5638727
Age: postnatal adult
Image: 2
Specimen Label: +
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5638727
Age: embryonic day 0.5
Image: 2
Specimen Label: 1C
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5638727
Age: embryonic day 1.0
Image: 2
Specimen Label: 2C
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:5638727
Age: embryonic day 2.0
Image: 2
Specimen Label: 4C
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5638727
Age: embryonic day 2.5
Image: 2
Specimen Label: 8C
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5638727
Age: embryonic day 3.0
Image: 2
Specimen Label: M
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5638727
Age: embryonic day 4.0
Image: 2
Specimen Label: B
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:7532791
Age: postnatal day 1
Specimen Label: d1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:7532791
Age: postnatal day 3
Specimen Label: d3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7532791
Age: postnatal day 5
Specimen Label: d5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7532791
Age: postnatal day 7
Specimen Label: d7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7532791
Age: postnatal day 9
Specimen Label: d9
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7532791
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:7532798
Age: postnatal day 1
Specimen Label: d1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:7532798
Age: postnatal day 3
Specimen Label: d3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7532798
Age: postnatal day 5
Specimen Label: d5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7532798
Age: postnatal day 7
Specimen Label: d7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7532798
Age: postnatal day 9
Specimen Label: d9
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5638697
Assay Type: RT-PCR
Annotation Date: 2023-10-04
Strength: Present
Sex: Male
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7532798
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3579528
Stage: TS28
Assay Id: MGI:3639606
Age: postnatal adult
Image: 2B
Specimen Label: 2B
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3639606
Age: embryonic day 14.5
Specimen Label: Not Shown
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Male
Emaps: EMAPS:3570728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 9
Note: Expressed in the nuclei of pachytene spermatocytes.
Specimen Label: 1h
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Male
Emaps: EMAPS:3570728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 15
Note: Expressed in the nuclei of preleptotene and pachytene spermatocytes.
Specimen Label: 1i
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Female
Emaps: EMAPS:2906728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 5
Specimen Label: 3e
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Female
Emaps: EMAPS:2906728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 9
Specimen Label: 3g
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3639606
Age: postnatal adult
Image: 1YY
Specimen Label: 1YY
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3639606
Age: embryonic day 14.5
Image: 8E
Specimen Label: 8E
Detected: true
Specimen Num: 24
GXD Expression  
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3601822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3639606
Age: embryonic day 14.5
Image: 3J
Specimen Label: 3J
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1825122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3639606
Age: embryonic day 14.5
Image: 3J
Specimen Label: 3J
Detected: true
Specimen Num: 13
GXD Expression
Probe: MGI:5638714
Assay Type: Immunohistochemistry
Annotation Date: 2015-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Diffuse
Stage: TS03
Assay Id: MGI:5638755
Age: embryonic day 2.0
Image: 4-cell
Note: Expression distributed diffusely throughout cytoplasm of each blastomere at all stages.
Specimen Label: 4-cell
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Female
Emaps: EMAPS:2986628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 5
Specimen Label: 3e
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Female
Emaps: EMAPS:2986628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 9
Specimen Label: 3g
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:7532714
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Male
Emaps: EMAPS:3148228
Stage: TS28
Assay Id: MGI:7532723
Age: postnatal day 5
Note: Not expressed in the spermatogonial cells at the basal side.
Specimen Label: 1g
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3639606
Age: postnatal day 8
Specimen Label: Not Shown
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3639606
Age: postnatal day 19
Image: 1S
Specimen Label: 1S
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3639585
Assay Type: RNA in situ
Annotation Date: 2006-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3518228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3639606
Age: postnatal day 8
Image: 6BB
Note: Expression is in cerebral cortex vessels in regions with a lower neuronal cell density.
Specimen Label: 6BB
Detected: true
Specimen Num: 20