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Search results 1 to 100 out of 1394 for Ccn2

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Type Details Score
Gene
1490 | CCN2
Type: gene
Organism: human
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Gene
476202 | CCN2
Type: gene
Organism: dog, domestic
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Gene
281103 | CCN2
Type: gene
Organism: cattle
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Gene
374135 | CCN2
Type: gene
Organism: chicken
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Gene
714520 | CCN2
Type: gene
Organism: macaque, rhesus
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Gene
548598 | ccn2
Type: gene
Organism: frog, western clawed
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Gene
64032 | Ccn2
Type: gene
Organism: rat
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Gene
463003 | CCN2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:95537 | Ccn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
122152366 | CCN2-AS1
Type: gene
Organism: human
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Publication
35045313 | J:319872
 
First Author: Petrosino JM
Year: 2022
Journal: Matrix Biol
Title: CCN2 participates in overload-induced skeletal muscle hypertrophy.
Volume: 106
Pages: 1-11
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Publication
24152728 | J:316685
First Author: Liu S
Year: 2013
Journal: Mol Biol Cell
Title: CCN2 modulates hair follicle cycling in mice.
Volume: 24
Issue: 24
Pages: 3939-44
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Publication
21533890 | J:176191
First Author: Liu S
Year: 2011
Journal: J Cell Commun Signal
Title: CCN2 is not required for skin development.
Volume: 5
Issue: 3
Pages: 179-82
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Publication
20936632 | J:171300
First Author: Liu S
Year: 2011
Journal: Arthritis Rheum
Title: CCN2 is required for bleomycin-induced skin fibrosis in mice.
Volume: 63
Issue: 1
Pages: 239-46
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Publication
26168233 | J:226336
First Author: Hutchenreuther J
Year: 2015
Journal: J Invest Dermatol
Title: CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis.
Volume: 135
Issue: 11
Pages: 2805-2813
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Publication
17239853 | J:119510
First Author: Kennedy L
Year: 2007
Journal: Exp Cell Res
Title: CCN2 is necessary for the function of mouse embryonic fibroblasts.
Volume: 313
Issue: 5
Pages: 952-64
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Expression in metanephric tubules in tubule terminals rather than uniformly throughout tubules.
Specimen Label: 6a CCN2
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3269722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Very high expression at some terminal ends of actively branching bronchioles.
Specimen Label: 3a CCN2
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in actively branching broncholes branching from little to no expression to higher levels.
Specimen Label: 3b CCN2
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1706824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in thyroid gland.
Specimen Label: 7a CCN2
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 8g CCN2
Detected: true
Specimen Num: 43
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3577820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Highly expressed in intestinal epithelium.
Specimen Label: 5b CCN2
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Lower expression at E14.
Specimen Label: 5c CCN2
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3577824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Much weaker expression by E16.
Specimen Label: 5d CCN2
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3286724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in veins and arteries.
Specimen Label: 2a CCN2
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3286724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in veins and arteries.
Specimen Label: S2A CCN2
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3268924
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: No expression in larger bronchi that are no longer branching.
Specimen Label: 3c CCN2
Detected: false
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2863724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in urothelium and smooth muscle.
Specimen Label: 6e CCN2
Detected: true
Specimen Num: 30
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Specimen Label: 2b CCN2
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 2c CCN2
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 2d CCN2
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3268824
Pattern: Widespread
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: At E16, expression decreased throughout myocardium relative to expression at E14.
Specimen Label: S2C CCN2
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 8f CCN2
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3146924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in veins and arteries.
Specimen Label: S2B CCN2
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3638520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Very low expression in intestinal smooth muscle.
Specimen Label: 5b CCN2
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3514824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in veins and arteries.
Specimen Label: 4b CCN2
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3598822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Very little expression in skeletal muscle. No accumulation of expresion at myotendinuous junctions.
Specimen Label: 4a CCN2
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3598824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very little expression in skeletal muscle. No accumulation of expresion at myotendinuous junctions.
Specimen Label: 4b CCN2
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603914
Pattern: Widespread
Stage: TS14
Assay Id: MGI:7532603
Age: embryonic day 9.0
Note: Expression detected in all organs, similar to that of Ccn5.
Specimen Label: S1A CCN2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Pattern: Widespread
Stage: TS18
Assay Id: MGI:7532603
Age: embryonic day 11.0
Note: Expression detected in all organs, similar to that of Ccn5.
Specimen Label: S1B CCN2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Differences in expression from Ccn5 beginning at E12.
Specimen Label: 1a CCN2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Expression in smaller number of cell types than Ccn5.
Specimen Label: 1b CCN2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in smaller number of cell types than Ccn5.
Specimen Label: 1c CCN2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in connective tissue of adrenal capsule.
Specimen Label: 7b CCN2
Detected: true
Specimen Num: 34
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Female
Emaps: EMAPS:3642824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Low levels of expression in epithelial cells and glands of reproductive tract
Specimen Label: 6g CCN2
Detected: true
Specimen Num: 32
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 5a CCN2
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
     
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 5a CCN2
Detected: false
Specimen Num: 22
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GXD Expression
GXD Expression
     
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 5a CCN2
Detected: false
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3628524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low levels of expression in veins and arteries.
Specimen Label: 4b CCN2
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1782924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in fused eyelid.
Specimen Label: 8g CCN2
Detected: true
Specimen Num: 43
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 8b CCN2
Detected: true
Specimen Num: 38
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 8c CCN2
Detected: true
Specimen Num: 39
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GXD Expression
GXD Expression
     
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760224
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Specimen Label: 8g CCN2
Detected: false
Specimen Num: 43
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression limitied to inner root sheath.
Specimen Label: 8e CCN2
Detected: true
Specimen Num: 41
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in chondrocytes during endochondral ossification. Expression primarily in hypertrophic and calcification zones.
Specimen Label: 4b CCN2
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in chondrocytes during endochondral ossification.
Specimen Label: 4c CCN2
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608914
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:7532603
Age: embryonic day 9.0
Specimen Label: S1A CCN2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Strong expression in nuclei of neurons.
Specimen Label: 8d CCN2
Detected: true
Specimen Num: 40
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Female
Emaps: EMAPS:3596224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Low levels of expression in epithelial cells and glands of reproductive tract
Specimen Label: 6g CCN2
Detected: true
Specimen Num: 32
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3544122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Very low expression in intestinal smooth muscle.
Specimen Label: 5c CCN2
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3544124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Very low expression in intestinal smooth muscle.
Specimen Label: 5d CCN2
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3649322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 2e CCN2
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Widespread
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Expression widely distributed in E12 brain.
Specimen Label: 8a CCN2
Detected: true
Specimen Num: 37
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Expression more restricted at E14.
Specimen Label: 8b CCN2
Detected: true
Specimen Num: 38
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•
•
•
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression more restricted at E16.
Specimen Label: 8c CCN2
Detected: true
Specimen Num: 39
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2860122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Expression only in urothelium.
Specimen Label: 6d CCN2
Detected: true
Specimen Num: 29
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•
•
•
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2860124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in urothelium and smooth muscle.
Specimen Label: 6e CCN2
Detected: true
Specimen Num: 30
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•
•
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1796222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Expression not described.
Specimen Label: 6f CCN2
Specimen Num: 31
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•
•
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Female
Emaps: EMAPS:1796224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Low levels of expression in ovary.
Specimen Label: 6g CCN2
Detected: true
Specimen Num: 32
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•
•
•
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression only in tubules at E16.
Specimen Label: 6b CCN2
Detected: true
Specimen Num: 27
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression only in tubules at E16.
Specimen Label: 6c CCN2
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1786922
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 2d CCN2
Detected: false
Specimen Num: 10
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3679320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7532603
Age: embryonic day 12.0
Note: Higher levels of expression in apex of heart when compared to myocardial expression levels.
Specimen Label: 2b CCN2
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3679322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Higher levels of expression in apex of heart when compared to myocardial expression levels.
Specimen Label: 2c CCN2
Detected: true
Specimen Num: 9
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3679322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: Higher levels of expression in apex of heart when compared to myocardial expression levels.
Specimen Label: 2d CCN2
Detected: true
Specimen Num: 10
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•
•
•
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GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3789624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in chondrocytes during endochondral ossification. Expression primarily in hypertrophic and calcification zones.
Specimen Label: 4b CCN2
Detected: true
Specimen Num: 20
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•
•
•
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3802824
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: No expression in hyaline cartilage in resting zone.
Specimen Label: 4b CCN2
Detected: false
Specimen Num: 20
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Publication
25554597 | J:220896
 
First Author: Aoyama E
Year: 2015
Journal: Bone
Title: CCN2 enhances RANKL-induced osteoclast differentiation via direct binding to RANK and OPG.
Volume: 73
Pages: 242-8
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•
•
•
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Publication
27734361 | J:239627
 
First Author: Yamaai T
Year: 2017
Journal: Methods Mol Biol
Title: Gene Expression Analysis of CCN Proteins: Whole-Mount In Situ Hybridization of Ccn2 in Developing Calcified Tissues.
Volume: 1489
Pages: 11-19
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Publication
36625347 | J:344611
 
First Author: Wang Y
Year: 2023
Journal: JCI Insight
Title: CCN2 deficiency in smooth muscle cells triggers cell reprogramming and aggravates aneurysm development.
Volume: 8
Issue: 1
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•
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Publication
18067859 | J:130332
First Author: Kawaki H
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Functional requirement of CCN2 for intramembranous bone formation in embryonic mice.
Volume: 366
Issue: 2
Pages: 450-6
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Publication
32423907 | J:304261
 
First Author: Ramovs V
Year: 2020
Journal: Life Sci Alliance
Title: Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.
Volume: 3
Issue: 7
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•
•
•
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Publication
23756156 | J:308154
 
First Author: Tsoutsman T
Year: 2013
Journal: J Mol Cell Cardiol
Title: CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure.
Volume: 62
Pages: 164-78
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•
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Publication
23530034 | J:316099
First Author: Tran CM
Year: 2013
Journal: J Biol Chem
Title: Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.
Volume: 288
Issue: 18
Pages: 12654-66
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GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1876724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Absent or extremely low levels of expression in thymus and spleen.
Specimen Label: CCN2 not shown
Specimen Num: 36
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3295224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Low levels of expression in exocrine ducts.
Specimen Label: CCN2 not shown
Detected: true
Specimen Num: 36
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286622
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Note: No expression in surrounding mesenchyme.
Specimen Label: 3a CCN2 inset
Detected: false
Specimen Num: 16
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Pattern: Widespread
Stage: TS16
Assay Id: MGI:7532603
Age: embryonic day 10.0
Note: Expression detected in all organs, similar to that of Ccn5.
Specimen Label: E10 CCN2 not shown
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Expression in nucleus of adrenal gland cells.
Specimen Label: 7b CCN2 inset
Detected: true
Specimen Num: 35
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1876824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7532603
Age: embryonic day 16.0
Note: Absent or extremely low levels of expression in thymus and spleen.
Specimen Label: CCN2 not shown
Specimen Num: 36
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6158951
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7532603
Age: embryonic day 14.0
Specimen Label: 3a CCN2 inset
Detected: true
Specimen Num: 16
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•
•
•
•
Publication
18597638 | J:155442
First Author: Kawaki H
Year: 2008
Journal: J Bone Miner Res
Title: Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage.
Volume: 23
Issue: 11
Pages: 1751-64
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•
•
•
•
Publication
23142580 | J:192362
First Author: Aoyama E
Year: 2012
Journal: FEBS Lett
Title: CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling.
Volume: 586
Issue: 24
Pages: 4270-5
•
•
•
•
•
Publication
24792956 | J:214663
 
First Author: Canalis E
Year: 2014
Journal: Bone
Title: Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.
Volume: 64
Pages: 273-80
•
•
•
•
•
Publication
24574231 | J:234752
First Author: Liu S
Year: 2014
Journal: Arthritis Rheumatol
Title: Skin progenitor cells contribute to bleomycin-induced skin fibrosis.
Volume: 66
Issue: 3
Pages: 707-13
•
•
•
•
•
Publication
31320136 | J:290888
First Author: Inoue T
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Cellular communication network factor 2 (CCN2) promotes the progression of acute kidney injury to chronic kidney disease.
Volume: 517
Issue: 1
Pages: 96-102
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•
•
•
•
Publication
32616521 | J:291297
     
First Author: Keenan CM
Year: 2020
Journal: Dis Model Mech
Title: Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of CCN2.
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•
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Publication
29885461 | J:271171
 
First Author: Hutchenreuther J
Year: 2018
Journal: Matrix Biol
Title: Activation of cancer-associated fibroblasts is required for tumor neovascularization in a murine model of melanoma.
Volume: 74
Pages: 52-61
•
•
•
•
•
Publication
31610176 | J:290652
First Author: Tsang M
Year: 2020
Journal: Am J Pathol
Title: Insights into Fibroblast Plasticity: Cellular Communication Network 2 Is Required for Activation of Cancer-Associated Fibroblasts in a Murine Model of Melanoma.
Volume: 190
Issue: 1
Pages: 206-221
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•
•
•
•
Publication
27662798 | J:237997
First Author: Chen L
Year: 2016
Journal: Am J Pathol
Title: Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p.
Volume: 186
Issue: 11
Pages: 2921-2933
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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