Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
CD160 is a GPI-anchored MHC-class I activating receptor mainly expressed on peripheral blood NK cells. It is also expressed on both cytolytic lymphocytes and some unstimulated CD4 T cells []. CD160 has different isoforms, including GPI-anchored isoform, a transmembrane isoform, and a secreted isoform. Upon specific engagement of CD160 by its physiological ligand HLA-C, or by mAb cross-linking, CD160 PB-NK cells produce significant levels of IFN-gamma, TNF-alpha, IL-6 as well as IL-8 and MIP-1beta []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai G |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator. |
Volume: |
9 |
Issue: |
2 |
Pages: |
176-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TJ |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
CD160 serves as a negative regulator of NKT cells in acute hepatic injury. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3258 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tu TC |
Year: |
2015 |
Journal: |
J Exp Med |
Title: |
CD160 is essential for NK-mediated IFN-γ production. |
Volume: |
212 |
Issue: |
3 |
Pages: |
415-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells. |
Volume: |
11 |
|
Pages: |
2188 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
185
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
141
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
185
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Maeda M |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Murine CD160, Ig-like receptor on NK cells and NKT cells, recognizes classical and nonclassical MHC class I and regulates NK cell activation. |
Volume: |
175 |
Issue: |
7 |
Pages: |
4426-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le Bouteiller P |
Year: |
2011 |
Journal: |
Immunol Lett |
Title: |
CD160: a unique activating NK cell receptor. |
Volume: |
138 |
Issue: |
2 |
Pages: |
93-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Del Rio ML |
Year: |
2022 |
Journal: |
Transl Res |
Title: |
The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection. |
Volume: |
239 |
|
Pages: |
103-123 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan CL |
Year: |
2018 |
Journal: |
Immunohorizons |
Title: |
CD160 Stimulates CD8+ T Cell Responses and Is Required for Optimal Protective Immunity to Listeria monocytogenes. |
Volume: |
2 |
Issue: |
7 |
Pages: |
238-250 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sadighi Akha AA |
Year: |
2015 |
Journal: |
Immunology |
Title: |
Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice. |
Volume: |
144 |
Issue: |
4 |
Pages: |
587-97 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Anumanthan A |
Year: |
1998 |
Journal: |
GenBank Submission |
Title: |
Mus musculus natural killer cell BY55 precursor, mRNA, complete cds |
|
|
Pages: |
AF060982 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shui JW |
Year: |
2012 |
Journal: |
Nature |
Title: |
HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria. |
Volume: |
488 |
Issue: |
7410 |
Pages: |
222-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ortonne N |
Year: |
2011 |
Journal: |
J Invest Dermatol |
Title: |
Human and mouse mast cells express and secrete the GPI-anchored isoform of CD160. |
Volume: |
131 |
Issue: |
4 |
Pages: |
916-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pawlak M |
Year: |
2022 |
Journal: |
Immunity |
Title: |
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. |
Volume: |
55 |
Issue: |
9 |
Pages: |
1663-1679.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abbasi F |
Year: |
2020 |
Journal: |
Cells |
Title: |
CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice. |
Volume: |
9 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Muscate F |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. |
Volume: |
9 |
|
Pages: |
2611 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park SJ |
Year: |
2020 |
Journal: |
mBio |
Title: |
Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection. |
Volume: |
11 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Seo GY |
Year: |
2018 |
Journal: |
Cell Host Microbe |
Title: |
LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. |
Volume: |
24 |
Issue: |
2 |
Pages: |
249-260.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seo GY |
Year: |
2022 |
Journal: |
Sci Immunol |
Title: |
Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection. |
Volume: |
7 |
Issue: |
73 |
Pages: |
eabm6931 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Y |
Year: |
2016 |
Journal: |
Sci Adv |
Title: |
Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM. |
Volume: |
2 |
Issue: |
4 |
Pages: |
e1500637 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bodnar JS |
Year: |
2002 |
Journal: |
Nat Genet |
Title: |
Positional cloning of the combined hyperlipidemia gene Hyplip1. |
Volume: |
30 |
Issue: |
1 |
Pages: |
110-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
28 |
Description: |
CD160 antigen |
Type: |
chain |
End: |
160 |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Component |
Name: |
CD160 antigen, soluble form |
|
•
•
•
•
•
|
Publication |
First Author: |
Anumanthan A |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. |
Volume: |
161 |
Issue: |
6 |
Pages: |
2780-90 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
28 |
Description: |
CD160 antigen, soluble form |
Type: |
chain |
End: |
160 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; gene trap OST3193, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; gene trap OST3292, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; targeted mutation 1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; targeted mutation 1, Yang-Xin Fu |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; gene trap 407C7, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
CD160 antigen; targeted mutation 1, Arlene H Sharpe |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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