Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Ogata H |
Year: |
2000 |
Journal: |
J Exp Med |
Title: |
The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. |
Volume: |
192 |
Issue: |
1 |
Pages: |
23-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyake K |
Year: |
1995 |
Journal: |
J Immunol |
Title: |
RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. |
Volume: |
154 |
Issue: |
7 |
Pages: |
3333-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bezhaeva T |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure. |
Volume: |
7 |
Issue: |
1 |
Pages: |
10269 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kani K |
Year: |
2023 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The innate immune receptor RP105 promotes metabolic syndrome by altering gut microbiota composition and intestinal barrier function. |
Volume: |
664 |
|
Pages: |
77-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bastiaansen AJ |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e99882 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyake K |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. |
Volume: |
161 |
Issue: |
3 |
Pages: |
1348-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Y |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
CD180 Ligation Inhibits TLR7- and TLR9-Mediated Activation of Macrophages and Dendritic Cells Through the Lyn-SHP-1/2 Axis in Murine Lupus. |
Volume: |
9 |
|
Pages: |
2643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roe K |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
Targeting Antigens to CD180 but Not CD40 Programs Immature and Mature B Cell Subsets to Become Efficient APCs. |
Volume: |
203 |
Issue: |
7 |
Pages: |
1715-1729 |
|
•
•
•
•
•
|
Publication |
First Author: |
Divanovic S |
Year: |
2005 |
Journal: |
Nat Immunol |
Title: |
Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. |
Volume: |
6 |
Issue: |
6 |
Pages: |
571-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chaplin JW |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway. |
Volume: |
187 |
Issue: |
8 |
Pages: |
4199-209 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karper JC |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation. |
Volume: |
8 |
Issue: |
7 |
Pages: |
e67923 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Wezel A |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response. |
Volume: |
6 |
|
Pages: |
24248 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagai Y |
Year: |
2012 |
Journal: |
Int Immunol |
Title: |
The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells. |
Volume: |
24 |
Issue: |
6 |
Pages: |
389-400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsukamoto H |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Reduced surface expression of TLR4 by a V254I point mutation accounts for the low lipopolysaccharide responder phenotype of BALB/c B cells. |
Volume: |
190 |
Issue: |
1 |
Pages: |
195-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allen JL |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Cutting edge: regulation of TLR4-driven B cell proliferation by RP105 is not B cell autonomous. |
Volume: |
188 |
Issue: |
5 |
Pages: |
2065-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakaguchi T |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes. |
Volume: |
31 |
Issue: |
10 |
Pages: |
107755 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagai Y |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes. |
Volume: |
174 |
Issue: |
11 |
Pages: |
7043-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karper JC |
Year: |
2013 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation. |
Volume: |
33 |
Issue: |
12 |
Pages: |
2810-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miura Y |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). |
Volume: |
38 |
Issue: |
3 |
Pages: |
299-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corcoran LM |
Year: |
1999 |
Journal: |
J Immunol |
Title: |
IL-5 and Rp105 signaling defects in B cells from commonly used 129 mouse substrains. |
Volume: |
163 |
Issue: |
11 |
Pages: |
5836-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Furuta T |
Year: |
2008 |
Journal: |
Eur J Immunol |
Title: |
Mast cell-mediated immune responses through IgE antibody and Toll-like receptor 4 by malarial peroxiredoxin. |
Volume: |
38 |
Issue: |
5 |
Pages: |
1341-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi T |
Year: |
2008 |
Journal: |
Int Immunol |
Title: |
Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice. |
Volume: |
20 |
Issue: |
7 |
Pages: |
881-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoon SI |
Year: |
2011 |
Journal: |
Nat Struct Mol Biol |
Title: |
An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1. |
Volume: |
18 |
Issue: |
9 |
Pages: |
1028-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chan CC |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain. |
Volume: |
12 |
Issue: |
1 |
Pages: |
2911 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kayagaki N |
Year: |
2013 |
Journal: |
Science |
Title: |
Noncanonical inflammasome activation by intracellular LPS independent of TLR4. |
Volume: |
341 |
Issue: |
6151 |
Pages: |
1246-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). |
Volume: |
275 |
Issue: |
29 |
Pages: |
22313-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Timmermans S |
Year: |
2018 |
Journal: |
JCI Insight |
Title: |
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. |
Volume: |
3 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
21 |
Description: |
CD180 antigen |
Type: |
chain |
End: |
661 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
661
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
CD180 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
CD180 antigen; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
86
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
69
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
105
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
41
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chaplin JW |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory. |
Volume: |
210 |
Issue: |
10 |
Pages: |
2135-46 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong G |
Year: |
2019 |
Journal: |
Biochim Biophys Acta Mol Basis Dis |
Title: |
Ligation of CD180 contributes to endotoxic shock by regulating the accumulation and immunosuppressive activity of myeloid-derived suppressor cells through STAT3. |
Volume: |
1865 |
Issue: |
3 |
Pages: |
535-546 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohto U |
Year: |
2011 |
Journal: |
J Mol Biol |
Title: |
Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family. |
Volume: |
413 |
Issue: |
4 |
Pages: |
815-25 |
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Allele |
Name: |
CD180 antigen; wild type |
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Allele |
Name: |
CD180 antigen; targeted mutation 1, Kensuke Miyake |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
mutant strain, congenic, targeted mutation |
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