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Search results 1 to 100 out of 850 for Cd200

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: OX2/CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor (CD200R) predominantly expressed on myeloid lineage cells [, ]. It is involved in regulation of macrophage function []. Interaction of CD200 with its receptor acts to suppress inflammatory responses [, , , ]. CD200 has been shown to play important roles in controlling autoimmunity, inflammation, the development and spread of cancer, hypersensitivity, and spontaneous fetal loss [].This entry also includes viral OX2 (vOX2). Viral OX2 is encoded by herpesvirurses and has significant homology with cellular OX2. Viral OX2 encodes a glycosylated cell surface protein which has been shown to target myeloid-lineage cells [].
Publication
First Author: Wright GJ
Year: 2003
Journal: J Immunol
Title: Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.
Volume: 171
Issue: 6
Pages: 3034-46
Publication
First Author: Hoek RM
Year: 2000
Journal: Science
Title: Down-regulation of the macrophage lineage through interaction with OX2 (CD200).
Volume: 290
Issue: 5497
Pages: 1768-71
Publication
First Author: Rygiel TP
Year: 2009
Journal: J Immunol
Title: Lack of CD200 enhances pathological T cell responses during influenza infection.
Volume: 183
Issue: 3
Pages: 1990-6
Publication
First Author: Copland DA
Year: 2007
Journal: Am J Pathol
Title: Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis.
Volume: 171
Issue: 2
Pages: 580-8
Publication
First Author: Rosenblum MD
Year: 2004
Journal: J Invest Dermatol
Title: Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?
Volume: 123
Issue: 5
Pages: 880-7
Publication
First Author: Broderick C
Year: 2002
Journal: Am J Pathol
Title: Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis.
Volume: 161
Issue: 5
Pages: 1669-77
Publication
First Author: Cohen M
Year: 2017
Journal: J Neurosci
Title: Newly Formed Endothelial Cells Regulate Myeloid Cell Activity Following Spinal Cord Injury via Expression of CD200 Ligand.
Volume: 37
Issue: 4
Pages: 972-985
Publication
First Author: Karnam G
Year: 2012
Journal: PLoS Pathog
Title: CD200 receptor controls sex-specific TLR7 responses to viral infection.
Volume: 8
Issue: 5
Pages: e1002710
Publication
First Author: Cui W
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts.
Volume: 104
Issue: 36
Pages: 14436-41
Publication
First Author: Rygiel TP
Year: 2012
Journal: Oncogene
Title: CD200-CD200R signaling suppresses anti-tumor responses independently of CD200 expression on the tumor.
Volume: 31
Issue: 24
Pages: 2979-88
Publication
First Author: Jenmalm MC
Year: 2006
Journal: J Immunol
Title: Regulation of myeloid cell function through the CD200 receptor.
Volume: 176
Issue: 1
Pages: 191-9
Publication
First Author: Snelgrove RJ
Year: 2008
Journal: Nat Immunol
Title: A critical function for CD200 in lung immune homeostasis and the severity of influenza infection.
Volume: 9
Issue: 9
Pages: 1074-83
Publication
First Author: Gorczynski R
Year: 2008
Journal: J Immunol
Title: An interaction between CD200 and monoclonal antibody agonists to CD200R2 in development of dendritic cells that preferentially induce populations of CD4+CD25+ T regulatory cells.
Volume: 180
Issue: 9
Pages: 5946-55
Publication
First Author: Chen Z
Year: 2016
Journal: PLoS One
Title: Over-Expression of CD200 Protects Mice from Dextran Sodium Sulfate Induced Colitis.
Volume: 11
Issue: 2
Pages: e0146681
Publication
First Author: Feng D
Year: 2019
Journal: Biochem Biophys Res Commun
Title: CD200 dysfunction in neuron contributes to synaptic deficits and cognitive impairment.
Volume: 516
Issue: 4
Pages: 1053-1059
Publication
First Author: Minas K
Year: 2006
Journal: Crit Rev Immunol
Title: Is the CD200/CD200 receptor interaction more than just a myeloid cell inhibitory signal?
Volume: 26
Issue: 3
Pages: 213-30
Publication
First Author: Gorczynski RM
Year: 2001
Journal: Eur J Immunol
Title: Transplant tolerance modifying antibody to CD200 receptor, but not CD200, alters cytokine production profile from stimulated macrophages.
Volume: 31
Issue: 8
Pages: 2331-7
Publication
First Author: Curry A
Year: 2017
Journal: PLoS One
Title: Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model.
Volume: 12
Issue: 2
Pages: e0171586
Publication
First Author: Zhang S
Year: 2004
Journal: J Immunol
Title: Molecular mechanisms of CD200 inhibition of mast cell activation.
Volume: 173
Issue: 11
Pages: 6786-93
Publication
First Author: Stack G
Year: 2015
Journal: PLoS Pathog
Title: CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.
Volume: 11
Issue: 2
Pages: e1004641
Publication
First Author: Sakthivel P
Year: 2017
Journal: Lung
Title: Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course.
Volume: 195
Issue: 1
Pages: 59-68
Publication
First Author: Hatherley D
Year: 2005
Journal: J Immunol
Title: Recombinant CD200 protein does not bind activating proteins closely related to CD200 receptor.
Volume: 175
Issue: 4
Pages: 2469-74
Publication
First Author: Comella Bolla A
Year: 2019
Journal: PLoS One
Title: CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease.
Volume: 14
Issue: 12
Pages: e0224901
Publication
First Author: Rosenblum MD
Year: 2004
Journal: Blood
Title: CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance.
Volume: 103
Issue: 7
Pages: 2691-8
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Barclay AN
Year: 2002
Journal: Trends Immunol
Title: CD200 and membrane protein interactions in the control of myeloid cells.
Volume: 23
Issue: 6
Pages: 285-90
Publication
First Author: Hayakawa K
Year: 2016
Journal: J Neurochem
Title: CD200 increases alternatively activated macrophages through cAMP-response element binding protein - C/EBP-beta signaling.
Volume: 136
Issue: 5
Pages: 900-6
Publication
First Author: Lyons A
Year: 2009
Journal: Brain Behav Immun
Title: Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.
Volume: 23
Issue: 7
Pages: 1020-7
Publication
First Author: Gorczynski R
Year: 2004
Journal: J Immunol
Title: CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules.
Volume: 172
Issue: 12
Pages: 7744-9
Publication
First Author: Chen DX
Year: 2005
Journal: Int Immunol
Title: Synthetic peptides from the N-terminal regions of CD200 and CD200R1 modulate immunosuppressive and anti-inflammatory effects of CD200-CD200R1 interaction.
Volume: 17
Issue: 3
Pages: 289-96
Publication  
First Author: Nicholls SM
Year: 2015
Journal: Exp Eye Res
Title: Local targeting of the CD200-CD200R axis does not promote corneal graft survival.
Volume: 130
Pages: 1-8
Publication
First Author: Taylor N
Year: 2005
Journal: J Immunol
Title: Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge.
Volume: 174
Issue: 1
Pages: 143-54
Publication
First Author: Costello DA
Year: 2011
Journal: J Biol Chem
Title: Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice: a role for Toll-like receptor activation.
Volume: 286
Issue: 40
Pages: 34722-32
Publication
First Author: Dentesano G
Year: 2014
Journal: Glia
Title: CD200R1 and CD200 expression are regulated by PPAR-γ in activated glial cells.
Volume: 62
Issue: 6
Pages: 982-98
Gene
Type: gene
Organism: human
Publication  
First Author: Cox FF
Year: 2013
Journal: Neuroscience
Title: The neural cell adhesion molecule-derived peptide, FGL, attenuates lipopolysaccharide-induced changes in glia in a CD200-dependent manner.
Volume: 235
Pages: 141-8
Publication
First Author: Loh KH
Year: 2016
Journal: Cell
Title: Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts.
Volume: 166
Issue: 5
Pages: 1295-1307.e21
Publication
First Author: Hatherley D
Year: 2013
Journal: Structure
Title: Structures of CD200/CD200 receptor family and implications for topology, regulation, and evolution.
Volume: 21
Issue: 5
Pages: 820-32
Publication
First Author: Simelyte E
Year: 2010
Journal: Clin Exp Immunol
Title: CD200R1 regulates the severity of arthritis but has minimal impact on the adaptive immune response.
Volume: 162
Issue: 1
Pages: 163-8
Publication
First Author: van den Borne P
Year: 2014
Journal: PLoS One
Title: The CD200-CD200 receptor inhibitory axis controls arteriogenesis and local T lymphocyte influx.
Volume: 9
Issue: 6
Pages: e98820
Publication
First Author: Rosenblum MD
Year: 2005
Journal: J Invest Dermatol
Title: Characterization of CD 200-receptor expression in the murine epidermis.
Volume: 125
Issue: 6
Pages: 1130-8
Publication  
First Author: Griffiths MR
Year: 2010
Journal: Int J Inflam
Title: The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review.
Volume: 2010
Pages: 151097
Publication
First Author: Holmannová D
Year: 2012
Journal: Acta Medica (Hradec Kralove)
Title: CD200/CD200R paired potent inhibitory molecules regulating immune and inflammatory responses; Part I: CD200/CD200R structure, activation, and function.
Volume: 55
Issue: 1
Pages: 12-7
Publication
First Author: Chung YH
Year: 2002
Journal: J Virol
Title: Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein activates myeloid-lineage cells to induce inflammatory cytokine production.
Volume: 76
Issue: 10
Pages: 4688-98
Publication
First Author: Rijkers ES
Year: 2008
Journal: Mol Immunol
Title: The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes.
Volume: 45
Issue: 4
Pages: 1126-35
Publication
First Author: Khan IZ
Year: 2021
Journal: Cancer Res
Title: The CD200-CD200R Axis Promotes Squamous Cell Carcinoma Metastasis via Regulation of Cathepsin K.
Volume: 81
Issue: 19
Pages: 5021-5032
Protein
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chen Z
Year: 1997
Journal: Biochim Biophys Acta
Title: Cloning and characterization of the murine homologue of the rat/human MRC OX-2 gene.
Volume: 1362
Issue: 1
Pages: 6-10
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Lung
Specimen Num: 2
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Kidney
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Spleen
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Fat
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Brain
Specimen Num: 7
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Femur
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7543818
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768128
Stage: TS28
Assay Id: MGI:7549345
Age: postnatal week 10
Image: 1
Specimen Label: Calvaria
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1914123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1914223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1910423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1910323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1910623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_01
Specimen Label: euxassay_010522_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1914123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_02
Specimen Label: euxassay_010522_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1914223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_02
Specimen Label: euxassay_010522_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4416264
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1910623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823720
Age: embryonic day 14.5
Image: euxassay_010522_02
Specimen Label: euxassay_010522_02
Detected: true
Specimen Num: 2