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Search results 1 to 100 out of 1275 for Cd28

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Type Details Score
Gene
940 | CD28
Type: gene
Organism: human
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Gene
396249 | CD28
Type: gene
Organism: chicken
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Gene
101886406 | cd28
Type: gene
Organism: zebrafish
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Gene
key_23259 | CD28
Type: gene
Organism: rabbit, European
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Gene
281050 | CD28
Type: gene
Organism: cattle
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Gene
705313 | CD28
Type: gene
Organism: macaque, rhesus
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Gene
100126210 | cd28
Type: gene
Organism: frog, western clawed
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Gene
25660 | Cd28
Type: gene
Organism: rat
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Gene
403646 | CD28
Type: gene
Organism: dog, domestic
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Gene
470617 | CD28
Type: gene
Organism: chimpanzee
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Protein Domain
IPR008093 | CD28
Type: Family
Description: Antigen (Ag) recognition by the T cell receptor (TCR) induces activation ofT lymphocytes. However, TCR-mediated signals alone are insufficient forefficient T cell activation, and additional co-stimulatory signals are required. One of the most important surface molecules that delivers co-stimulatory signals for T cells is CD28. The human T lymphocyte Ag CD28 (Tp44) is a homodimeric 90kDa glycoprotein expressed on the surface of themajority of human peripheral T cells and lymphocytes. Stimulation of CD4+ Tcells in the absence of CD28 co-signalling causes impaired proliferation, reduced cytokine production and altered generation of helper T cell subsets.Co-stimulation via CD28 promotes T cell viability, clonal expansion,cytokine production and effector functions, while also regulating apoptosisof activated T cells, suggesting its importance in regulating long-term T cell survival [, , , ].Ligands for CD28 and the structurally related CTLA-4 (CD152) are themolecules B7.1 (CD80) and B7.2 (CD86). B7.1 and B7.2 are expressed onprofessional antigen presenting cells (APCs) and their expression is up-regulated during an immune response. Ligation of CD28 by its natural ligandsresults in tyrosine phosphorylation at a YMNM motif within its cytoplasmictail. The phosphorylated motif subsequently interacts with the Src homology2 domain in the p85 regulatory subunit of P13K, activating the p110 catalytic subunit. One of the P13K-dependent downstream targets, resulting from the antibody cross-linking of CD28, is the phoshporylation and activation of Akt (or PKB). Constitutively active Akt is able to substitutefor CD28 signals, and stimulates IL-2 production when introduced into matureCD28-deficient cells. Another molecule affected by CD28 stimulation is theproto-oncogene Vav, which acts as a guanine-nucleotide exchange factor forRac and CDC42, allowing these molecules to switch from the inactive GDP-bound state to the active GTP-bound state [, ].Another interesting feature of CD28, is its ability to induce expression ofPDE7, a cAMP phosphodiesterase, thus reducing cellular cAMP levels. cAMP hasbeen reported to affect nearly every pathway important for lymphocyteactivation, leading to inhibition of T cell proliferation. Specifically,increased intracellular cAMP has been implicated in the induction of T cellanergy, a non-responsive state that occurs after T cells are stimulatedthrough TCR/CD3 in the absence of co-stimulation. This can have therapeutic implications, in that blockage of CD28 co-stimulation can be profoundlyimmunosuppressive, preventing induction of pathogenic T cell responses inautoimmune disease models, and allowing for prolonged acceptance of allografts in models of organ transplantation []. Finally, CD28 co-stimulation directly controls T cell cycle progression by down-regulating the cdk inhibitor p27kip1, which actually integratesmitogenic MEK and P13K-dependent signals from both TCR and CD28 [].
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Protein Coding Gene
MGI:88327 | Cd28
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
2157764 | J:23361
First Author: Gross JA
Year: 1990
Journal: J Immunol
Title: The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression.
Volume: 144
Issue: 8
Pages: 3201-10
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Publication
11698433 | J:72680
First Author: Mittrücker HW
Year: 2001
Journal: J Immunol
Title: Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes.
Volume: 167
Issue: 10
Pages: 5620-7
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Publication
11698427 | J:72679
First Author: Suresh M
Year: 2001
Journal: J Immunol
Title: Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory.
Volume: 167
Issue: 10
Pages: 5565-73
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Protein
P31041
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Protein
Q8CDB3
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Publication
2162892 | -
First Author: Lee KP
Year: 1990
Journal: J Immunol
Title: The genomic organization of the CD28 gene. Implications for the regulation of CD28 mRNA expression and heterogeneity.
Volume: 145
Issue: 1
Pages: 344-52
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Publication
11884439 | -
First Author: Appleman LJ
Year: 2002
Journal: J Immunol
Title: CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.
Volume: 168
Issue: 6
Pages: 2729-36
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Publication
11827987 | -
First Author: Frauwirth KA
Year: 2002
Journal: J Clin Invest
Title: Activation and inhibition of lymphocytes by costimulation.
Volume: 109
Issue: 3
Pages: 295-9
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Publication
8648099 | J:110668
First Author: Ferguson SE
Year: 1996
Journal: J Immunol
Title: CD28 is required for germinal center formation.
Volume: 156
Issue: 12
Pages: 4576-81
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Publication
11837936 | J:113015
First Author: Boone DL
Year: 2002
Journal: Inflamm Bowel Dis
Title: Interleukin-2-deficient mice develop colitis in the absence of CD28 costimulation.
Volume: 8
Issue: 1
Pages: 35-42
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Publication
8943384 | J:37043
First Author: Kondo S
Year: 1996
Journal: J Immunol
Title: Contribution of the CD28 molecule to allergic and irritant-induced skin reactions in CD28 -/- mice.
Volume: 157
Issue: 11
Pages: 4822-9
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Publication
10586076 | J:58984
First Author: Mittrücker HW
Year: 1999
Journal: J Immunol
Title: Critical role of CD28 in protective immunity against Salmonella typhimurium.
Volume: 163
Issue: 12
Pages: 6769-76
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Publication
11276203 | J:68634
First Author: Okkenhaug K
Year: 2001
Journal: Nat Immunol
Title: A point mutation in CD28 distinguishes proliferative signals from survival signals.
Volume: 2
Issue: 4
Pages: 325-32
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Publication
12672399 | J:82789
First Author: Chapoval SP
Year: 2003
Journal: Clin Immunol
Title: CD28 costimulation is critical for experimental allergic asthma in HLA-DQ8 transgenic mice.
Volume: 106
Issue: 2
Pages: 83-94
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Publication
23966623 | J:205860
First Author: Byrum JN
Year: 2013
Journal: J Immunol
Title: CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts.
Volume: 191
Issue: 6
Pages: 3073-81
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Publication
18354182 | J:132988
First Author: Suzuki T
Year: 2008
Journal: J Immunol
Title: Induction of antitumor immune response by homeostatic proliferation and CD28 signaling.
Volume: 180
Issue: 7
Pages: 4596-605
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Publication
16495554 | J:107388
First Author: Honstettre A
Year: 2006
Journal: Infect Immun
Title: Role for the CD28 molecule in the control of Coxiella burnetii infection.
Volume: 74
Issue: 3
Pages: 1800-8
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Publication
21530327 | J:172609
First Author: Yao S
Year: 2011
Journal: Immunity
Title: B7-h2 is a costimulatory ligand for CD28 in human.
Volume: 34
Issue: 5
Pages: 729-40
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Publication
9295036 | J:42096
First Author: Wen T
Year: 1997
Journal: Eur J Immunol
Title: CD28 is not required for rejection of unmanipulated syngeneic and autologous tumors.
Volume: 27
Issue: 8
Pages: 1988-93
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Publication
11350825 | J:114405
First Author: Burr JS
Year: 2001
Journal: Am J Respir Cell Mol Biol
Title: CD28 and CTLA4 coordinately regulate airway inflammatory cell recruitment and T-helper cell differentiation after inhaled allergen.
Volume: 24
Issue: 5
Pages: 563-8
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Publication
14501867 | J:126214
First Author: Habiro K
Year: 2003
Journal: Transplantation
Title: Mechanism of allorecognition and skin graft rejection in CD28 and CD40 ligand double-deficient mice.
Volume: 76
Issue: 5
Pages: 854-8
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Publication
12515810 | J:109348
First Author: Vacchio MS
Year: 2003
Journal: J Exp Med
Title: CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells.
Volume: 197
Issue: 1
Pages: 19-26
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Publication
10510372 | J:119231
First Author: Yin D
Year: 1999
Journal: J Immunol
Title: Ligation of CD28 in vivo induces CD40 ligand expression and promotes B cell survival.
Volume: 163
Issue: 8
Pages: 4328-34
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Publication
24048955 | J:203113
First Author: Ogawa S
Year: 2013
Journal: Int Immunol
Title: CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.
Volume: 25
Issue: 12
Pages: 671-81
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Publication
9144484 | J:110667
First Author: Vella AT
Year: 1997
Journal: J Immunol
Title: CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.
Volume: 158
Issue: 10
Pages: 4714-20
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Publication
8676089 | J:110685
First Author: Saha B
Year: 1996
Journal: J Exp Med
Title: Protection against lethal toxic shock by targeted disruption of the CD28 gene.
Volume: 183
Issue: 6
Pages: 2675-80
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Publication
32579940 | J:308384
First Author: Utley A
Year: 2020
Journal: Cell Rep
Title: CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.
Volume: 31
Issue: 12
Pages: 107815
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Publication
12193694 | J:120690
First Author: Gray Parkin K
Year: 2002
Journal: J Immunol
Title: Expression of CD28 by bone marrow stromal cells and its involvement in B lymphopoiesis.
Volume: 169
Issue: 5
Pages: 2292-302
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Publication
10502560 | J:59459
First Author: Mathur M
Year: 1999
Journal: Am J Respir Cell Mol Biol
Title: CD28 interactions with either CD80 or CD86 are sufficient to induce allergic airway inflammation in mice.
Volume: 21
Issue: 4
Pages: 498-509
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Publication
16600196 | J:108140
First Author: Fukada K
Year: 2005
Journal: Cell Immunol
Title: CD28 is required for induction and maintenance of immunological memory in toxin-reactive CD4+ T cells in vivo.
Volume: 238
Issue: 2
Pages: 103-12
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Publication
11801669 | J:127289
First Author: Compton HL
Year: 2002
Journal: J Immunol
Title: CD28 costimulation and parasite dose combine to influence the susceptibility of BALB/c mice to infection with Leishmania major.
Volume: 168
Issue: 3
Pages: 1302-8
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Publication
15314039 | J:93659
First Author: Gao JX
Year: 2004
Journal: Int Immunol
Title: A new role for CD28 in the survival of autoreactive T cells in the periphery after chronic exposure to autoantigen.
Volume: 16
Issue: 10
Pages: 1403-9
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Publication
15634900 | J:95837
First Author: Elias RM
Year: 2005
Journal: J Immunol
Title: Role of CD28 in polyclonal and specific T and B cell responses required for protection against blood stage malaria.
Volume: 174
Issue: 2
Pages: 790-9
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Publication
9126966 | J:110674
First Author: Gause WC
Year: 1997
Journal: J Immunol
Title: CD28 dependence of T cell differentiation to IL-4 production varies with the particular type 2 immune response.
Volume: 158
Issue: 9
Pages: 4082-7
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Publication
31885821 | J:292418
 
First Author: Cong P
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD28 Deficiency Ameliorates Thoracic Blast Exposure-Induced Oxidative Stress and Apoptosis in the Brain through the PI3K/Nrf2/Keap1 Signaling Pathway.
Volume: 2019
Pages: 8460290
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Publication
15210826 | J:90926
First Author: Kimzey SL
Year: 2004
Journal: J Immunol
Title: Requirement for CD28 in the effector phase of allergic airway inflammation.
Volume: 173
Issue: 1
Pages: 632-40
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Publication
11544297 | J:118768
First Author: Rivas FV
Year: 2001
Journal: J Immunol
Title: CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Volume: 167
Issue: 6
Pages: 3123-8
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Publication
18056348 | J:155039
First Author: Iliopoulou BP
Year: 2007
Journal: J Immunol
Title: CD28 deficiency exacerbates joint inflammation upon Borrelia burgdorferi infection, resulting in the development of chronic Lyme arthritis.
Volume: 179
Issue: 12
Pages: 8076-82
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Publication
22068237 | J:179677
First Author: Sanchez-Lockhart M
Year: 2011
Journal: J Immunol
Title: Cutting edge: A role for inside-out signaling in TCR regulation of CD28 ligand binding.
Volume: 187
Issue: 11
Pages: 5515-9
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Publication
31565151 | J:293126
 
First Author: Liu Y
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD28 Deficiency Ameliorates Blast Exposure-Induced Lung Inflammation, Oxidative Stress, Apoptosis, and T Cell Accumulation in the Lungs via the PI3K/Akt/FoxO1 Signaling Pathway.
Volume: 2019
Pages: 4848560
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Publication
10415032 | J:119606
First Author: Leung BL
Year: 1999
Journal: J Immunol
Title: TCR alpha beta-independent CD28 signaling and costimulation require non-CD4-associated Lck.
Volume: 163
Issue: 3
Pages: 1334-41
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Publication
17056536 | J:140523
First Author: Graham DB
Year: 2006
Journal: J Immunol
Title: CD28 ligation costimulates cell death but not maturation of double-positive thymocytes due to defective ERK MAPK signaling.
Volume: 177
Issue: 9
Pages: 6098-107
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Publication
10605050 | J:125983
First Author: Toto P
Year: 2000
Journal: J Immunol
Title: Immune modulation in pemphigus vulgaris: role of CD28 and IL-10.
Volume: 164
Issue: 1
Pages: 522-9
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Publication
19398586 | J:149888
First Author: Dodson LF
Year: 2009
Journal: Mol Cell Biol
Title: Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation.
Volume: 29
Issue: 13
Pages: 3710-21
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Publication
1713603 | J:11356
First Author: Harper K
Year: 1991
Journal: J Immunol
Title: CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location.
Volume: 147
Issue: 3
Pages: 1037-44
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Publication
17463170 | J:145393
First Author: Singh N
Year: 2007
Journal: Blood
Title: Role of CD28 in fatal autoimmune disorder in scurfy mice.
Volume: 110
Issue: 4
Pages: 1199-206
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Publication
15385476 | J:93119
First Author: Rummel T
Year: 2004
Journal: Infect Immun
Title: CD28 costimulation is required for the expression of T-cell-dependent cell-mediated immunity against blood-stage Plasmodium chabaudi malaria parasites.
Volume: 72
Issue: 10
Pages: 5768-74
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Publication
27122236 | J:247108
First Author: Fröhlich M
Year: 2016
Journal: Eur J Immunol
Title: Interrupting CD28 costimulation before antigen rechallenge affects CD8(+) T-cell expansion and effector functions during secondary response in mice.
Volume: 46
Issue: 7
Pages: 1644-55
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Publication
12096029 | J:113535
First Author: Christensen JE
Year: 2002
Journal: Int Immunol
Title: Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells.
Volume: 14
Issue: 7
Pages: 701-11
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Publication
16908623 | J:124570
First Author: Friend LD
Year: 2006
Journal: J Exp Med
Title: A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant.
Volume: 203
Issue: 9
Pages: 2121-33
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Publication
12193687 | J:120676
First Author: Zhang J
Year: 2002
Journal: J Immunol
Title: Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination.
Volume: 169
Issue: 5
Pages: 2236-40
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Publication
12047751 | J:113529
First Author: Reiter R
Year: 2002
Journal: Immunology
Title: Impaired germinal centre formation and humoral immune response in the absence of CD28 and interleukin-4.
Volume: 106
Issue: 2
Pages: 222-8
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Publication
30320878 | J:269336
First Author: Uri A
Year: 2018
Journal: Eur J Immunol
Title: During acute graft versus host disease CD28 deletion in donor CD8+ , but not CD4+ , T cells maintain antileukemia responses in mice.
Volume: 48
Issue: 12
Pages: 2055-2067
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Publication
27460989 | J:260551
First Author: Dobbins J
Year: 2016
Journal: Sci Signal
Title: Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.
Volume: 9
Issue: 438
Pages: ra75
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Publication
32457739 | J:308194
 
First Author: Mitra A
Year: 2020
Journal: Front Immunol
Title: CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.
Volume: 11
Pages: 735
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Publication
32765524 | J:305696
 
First Author: Leddon SA
Year: 2020
Journal: Front Immunol
Title: The CD28 Transmembrane Domain Contains an Essential Dimerization Motif.
Volume: 11
Pages: 1519
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8752911 | J:110619
First Author: Noel PJ
Year: 1996
Journal: J Immunol
Title: CD28 costimulation prevents cell death during primary T cell activation.
Volume: 157
Issue: 2
Pages: 636-42
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Publication
10477604 | J:119602
First Author: Villegas EN
Year: 1999
Journal: J Immunol
Title: Role of CD28 in the generation of effector and memory responses required for resistance to Toxoplasma gondii.
Volume: 163
Issue: 6
Pages: 3344-53
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Publication
15128767 | J:89806
First Author: Andres PG
Year: 2004
Journal: J Immunol
Title: CD28 signals in the immature immunological synapse.
Volume: 172
Issue: 10
Pages: 5880-6
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Publication
24516382 | J:225162
First Author: Ndlovu H
Year: 2014
Journal: PLoS Pathog
Title: Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.
Volume: 10
Issue: 2
Pages: e1003906
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10779746 | J:110821
First Author: Howland KC
Year: 2000
Journal: J Immunol
Title: The roles of CD28 and CD40 ligand in T cell activation and tolerance.
Volume: 164
Issue: 9
Pages: 4465-70
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Publication
10201986 | J:112149
First Author: Oliveira-dos-Santos AJ
Year: 1999
Journal: J Immunol
Title: CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis.
Volume: 162
Issue: 8
Pages: 4490-5
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Publication
34214472 | J:313727
First Author: Béziat V
Year: 2021
Journal: Cell
Title: Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy.
Volume: 184
Issue: 14
Pages: 3812-3828.e30
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Publication
19190244 | J:148122
First Author: Alcázar I
Year: 2009
Journal: Blood
Title: p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.
Volume: 113
Issue: 14
Pages: 3198-208
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Publication
16517696 | J:129367
First Author: Lyddane C
Year: 2006
Journal: J Immunol
Title: Cutting Edge: CD28 controls dominant regulatory T cell activity during active immunization.
Volume: 176
Issue: 6
Pages: 3306-10
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Publication
14581610 | J:86461
First Author: Hendriks J
Year: 2003
Journal: J Exp Med
Title: CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool.
Volume: 198
Issue: 9
Pages: 1369-80
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Publication
1320641 | J:1556
First Author: Gross JA
Year: 1992
Journal: J Immunol
Title: Identification and distribution of the costimulatory receptor CD28 in the mouse.
Volume: 149
Issue: 2
Pages: 380-8
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Publication
20713624 | J:165030
First Author: Felonato M
Year: 2010
Journal: Infect Immun
Title: CD28 exerts protective and detrimental effects in a pulmonary model of paracoccidioidomycosis.
Volume: 78
Issue: 11
Pages: 4922-35
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Publication
25533288 | J:232694
First Author: Franckaert D
Year: 2015
Journal: Immunol Cell Biol
Title: Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells.
Volume: 93
Issue: 4
Pages: 417-23
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Publication
14701943 | J:119838
First Author: van den Brandt J
Year: 2004
Journal: Mol Endocrinol
Title: Resistance of single-positive thymocytes to glucocorticoid-induced apoptosis is mediated by CD28 signaling.
Volume: 18
Issue: 3
Pages: 687-95
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Publication
15004555 | J:89205
First Author: Andres PG
Year: 2004
Journal: Nat Immunol
Title: Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.
Volume: 5
Issue: 4
Pages: 435-42
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Publication
12752681 | J:83722
First Author: Vinay DS
Year: 2003
Journal: Immunol Cell Biol
Title: Immunity in the absence of CD28 and CD137 (4-1BB) molecules.
Volume: 81
Issue: 3
Pages: 176-84
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Publication
20421644 | J:161233
First Author: Lio CW
Year: 2010
Journal: J Immunol
Title: CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors.
Volume: 184
Issue: 11
Pages: 6007-13
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Publication
10477582 | J:57601
First Author: Tada Y
Year: 1999
Journal: J Immunol
Title: Role of the costimulatory molecule CD28 in the development of lupus in MRL/lpr mice.
Volume: 163
Issue: 6
Pages: 3153-9
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Publication
12946999 | J:86920
First Author: Nguyen P
Year: 2003
Journal: Blood
Title: Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function.
Volume: 102
Issue: 13
Pages: 4320-5
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Publication
18780833 | J:142613
First Author: Beyersdorf N
Year: 2008
Journal: Blood
Title: Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody.
Volume: 112
Issue: 10
Pages: 4328-36
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Publication
15488732 | J:105590
First Author: Martins GA
Year: 2004
Journal: Microbes Infect
Title: CD28 is required for T cell activation and IFN-gamma production by CD4+ and CD8+ T cells in response to Trypanosoma cruzi infection.
Volume: 6
Issue: 13
Pages: 1133-44
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Publication
12055251 | J:123794
First Author: Ekkens MJ
Year: 2002
Journal: J Immunol
Title: Memory Th2 effector cells can develop in the absence of B7-1/B7-2, CD28 interactions, and effector Th cells after priming with an intestinal nematode parasite.
Volume: 168
Issue: 12
Pages: 6344-51
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Publication
24639356 | J:210000
First Author: Boomer JS
Year: 2014
Journal: J Immunol
Title: Cutting edge: A double-mutant knockin of the CD28 YMNM and PYAP motifs reveals a critical role for the YMNM motif in regulation of T cell proliferation and Bcl-xL expression.
Volume: 192
Issue: 8
Pages: 3465-9
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Publication
7822814 | J:22492
First Author: Abe R
Year: 1995
Journal: J Immunol
Title: Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation.
Volume: 154
Issue: 3
Pages: 985-97
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Publication
23896981 | J:203007
First Author: Yousefi M
Year: 2013
Journal: Eur J Immunol
Title: CD28 controls the development of innate-like CD8+ T cells by promoting the functional maturation of NKT cells.
Volume: 43
Issue: 11
Pages: 3017-27
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Publication
14707048 | J:87357
First Author: Sempowski GD
Year: 2004
Journal: J Immunol
Title: CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis.
Volume: 172
Issue: 2
Pages: 787-94
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Publication
19646680 | J:152804
First Author: Shilling RA
Year: 2009
Journal: Cell Immunol
Title: CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo.
Volume: 259
Issue: 2
Pages: 177-84
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9436464 | J:40980
First Author: Toyo-oka K
Year: 1997
Journal: Immunol Lett
Title: Synergy between CD28 and CD9 costimulation for naive T-cell activation.
Volume: 58
Issue: 1
Pages: 19-23
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Publication
17114476 | J:140689
First Author: Fang M
Year: 2006
Journal: J Immunol
Title: Direct CD28 costimulation is required for CD8+ T cell-mediated resistance to an acute viral disease in a natural host.
Volume: 177
Issue: 11
Pages: 8027-36
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Publication
26711629 | J:246644
First Author: Win SJ
Year: 2016
Journal: Eur J Immunol
Title: In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice.
Volume: 46
Issue: 5
Pages: 1193-202
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Publication
14734751 | J:87657
First Author: Demirci G
Year: 2004
Journal: J Immunol
Title: Critical role of OX40 in CD28 and CD154-independent rejection.
Volume: 172
Issue: 3
Pages: 1691-8
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Publication
14500627 | J:120383
First Author: Tang Q
Year: 2003
Journal: J Immunol
Title: Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells.
Volume: 171
Issue: 7
Pages: 3348-52
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