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Search results 1 to 100 out of 505 for Cd2ap

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0.441s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: CD2-associated protein (CD2AP) may function in dynamic actin remodelling and membrane trafficking during endocytosis []. During late anaphase and telophase, it localises to the microtubule midzone and telophase midbody. It may also play an role in cytokinesis [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:3821034
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826202
Age: embryonic day 14.5
Image: Additional file 4 Cd2ap
Specimen Label: Additional file 4 Cd2ap
Detected: true
Specimen Num: 1
Publication
First Author: Tossidou I
Year: 2012
Journal: Mol Cell Biol
Title: CD2AP regulates SUMOylation of CIN85 in podocytes.
Volume: 32
Issue: 6
Pages: 1068-79
Protein
Organism: Mus musculus/domesticus
Length: 637  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 637  
Fragment?: false
GXD Expression    
Probe: MGI:6450769
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6450786
Age: embryonic day 18.5
Specimen Label: 3 CD2AP Nphs1+/+
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6450769
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6450786
Age: embryonic day 18.5
Note: Absence of nephrin did not affect expression.
Specimen Label: 3 CD2AP Nphs1-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6455457
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6455484
Age: postnatal adult
Specimen Label: S7 CD2AP MIM+/+
Detected: true
Specimen Num: 1
Protein
Organism: Mus musculus/domesticus
Length: 532  
Fragment?: false
Publication
First Author: Cochran JN
Year: 2015
Journal: Hum Mol Genet
Title: The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity.
Volume: 24
Issue: 23
Pages: 6667-74
Publication
First Author: Welsch T
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Association of CD2AP with dynamic actin on vesicles in podocytes.
Volume: 289
Issue: 5
Pages: F1134-43
Publication
First Author: Takano T
Year: 2019
Journal: Kidney Int
Title: Recessive mutation in CD2AP causes focal segmental glomerulosclerosis in humans and mice.
Volume: 95
Issue: 1
Pages: 57-61
Publication
First Author: Grunkemeyer JA
Year: 2005
Journal: J Biol Chem
Title: CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency.
Volume: 280
Issue: 33
Pages: 29677-81
Protein
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: false
Publication
First Author: Monzo P
Year: 2005
Journal: Mol Biol Cell
Title: Clues to CD2-associated protein involvement in cytokinesis.
Volume: 16
Issue: 6
Pages: 2891-902
Publication
First Author: Shih NY
Year: 2001
Journal: Am J Pathol
Title: CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain.
Volume: 159
Issue: 6
Pages: 2303-8
Publication
First Author: Tsuji K
Year: 2017
Journal: Sci Rep
Title: Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy.
Volume: 7
Issue: 1
Pages: 8321
Publication
First Author: Schwarz K
Year: 2001
Journal: J Clin Invest
Title: Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.
Volume: 108
Issue: 11
Pages: 1621-9
Publication
First Author: Tolvanen TA
Year: 2015
Journal: J Cell Sci
Title: Lack of CD2AP disrupts Glut4 trafficking and attenuates glucose uptake in podocytes.
Volume: 128
Issue: 24
Pages: 4588-600
Publication
First Author: Ojelade SA
Year: 2019
Journal: Cell Rep
Title: cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Volume: 28
Issue: 7
Pages: 1799-1813.e5
Publication
First Author: Russo LM
Year: 2013
Journal: FEBS Lett
Title: Albuminuria associated with CD2AP knockout mice is primarily due to dysfunction of the renal degradation pathway processing of filtered albumin.
Volume: 587
Issue: 22
Pages: 3738-41
Publication
First Author: Wasik AA
Year: 2012
Journal: Mol Biol Cell
Title: Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.
Volume: 23
Issue: 17
Pages: 3370-9
Publication
First Author: Tsui CC
Year: 2008
Journal: J Neurosci
Title: CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.
Volume: 28
Issue: 35
Pages: 8789-800
Publication
First Author: Harrison BJ
Year: 2016
Journal: J Neurosci
Title: The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.
Volume: 36
Issue: 15
Pages: 4259-75
Publication
First Author: Yaddanapudi S
Year: 2011
Journal: J Clin Invest
Title: CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
Volume: 121
Issue: 10
Pages: 3965-80
Publication  
First Author: Brunskill EW
Year: 2015
Journal: BMC Nephrol
Title: Pathogenic pathways are activated in each major cell type of the glomerulus in the Cd2ap mutant mouse model of focal segmental glomerulosclerosis.
Volume: 16
Pages: 71
Publication
First Author: Shih NY
Year: 1999
Journal: Science
Title: Congenital nephrotic syndrome in mice lacking CD2-associated protein.
Volume: 286
Issue: 5438
Pages: 312-5
Publication
First Author: Kim JM
Year: 2003
Journal: Science
Title: CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.
Volume: 300
Issue: 5623
Pages: 1298-300
Publication
First Author: Zhang H
Year: 2018
Journal: Hepatology
Title: CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.
Volume: 68
Issue: 5
Pages: 1710-1725
Publication  
First Author: Liao F
Year: 2015
Journal: Mol Neurodegener
Title: Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.
Volume: 10
Pages: 12
Publication
First Author: Srivatsan S
Year: 2013
Journal: J Immunol
Title: CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production.
Volume: 191
Issue: 12
Pages: 5933-40
Publication
First Author: Peters I
Year: 2006
Journal: J Am Soc Nephrol
Title: IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes.
Volume: 17
Issue: 6
Pages: 1644-56
Publication
First Author: Schiffer M
Year: 2004
Journal: J Biol Chem
Title: A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis.
Volume: 279
Issue: 35
Pages: 37004-12
Publication
First Author: Kwon SH
Year: 2016
Journal: J Biol Chem
Title: Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex.
Volume: 291
Issue: 49
Pages: 25462-25475
Publication
First Author: Bredemeyer AJ
Year: 2009
Journal: Dev Biol
Title: The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage.
Volume: 325
Issue: 1
Pages: 211-24
Publication
First Author: Tossidou I
Year: 2007
Journal: J Biol Chem
Title: CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.
Volume: 282
Issue: 10
Pages: 7457-64
Publication
First Author: Saurus P
Year: 2017
Journal: Sci Rep
Title: Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis.
Volume: 7
Issue: 1
Pages: 10731
Publication
First Author: Lehtonen S
Year: 2000
Journal: J Biol Chem
Title: In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.
Volume: 275
Issue: 42
Pages: 32888-93
Publication
First Author: Roselli S
Year: 2004
Journal: Mol Cell Biol
Title: Early glomerular filtration defect and severe renal disease in podocin-deficient mice.
Volume: 24
Issue: 2
Pages: 550-60
Publication
First Author: Huber TB
Year: 2006
Journal: J Clin Invest
Title: Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin.
Volume: 116
Issue: 5
Pages: 1337-45
Publication
First Author: Fan Q
Year: 2006
Journal: Kidney Int
Title: The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.
Volume: 69
Issue: 7
Pages: 1207-15
Publication
First Author: Tossidou I
Year: 2010
Journal: J Biol Chem
Title: CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes.
Volume: 285
Issue: 33
Pages: 25285-95
Publication  
First Author: Kuusela S
Year: 2016
Journal: Cell Death Dis
Title: Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.
Volume: 7
Pages: e2302
Publication
First Author: Lehtonen S
Year: 2008
Journal: Differentiation
Title: CD2-associated protein is widely expressed and differentially regulated during embryonic development.
Volume: 76
Issue: 5
Pages: 506-17
Publication
First Author: Xavier S
Year: 2009
Journal: J Am Soc Nephrol
Title: TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes.
Volume: 20
Issue: 10
Pages: 2127-37
Publication
First Author: Shen R
Year: 2020
Journal: Transl Neurodegener
Title: Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 26
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee KH
Year: 2003
Journal: Science
Title: The immunological synapse balances T cell receptor signaling and degradation.
Volume: 302
Issue: 5648
Pages: 1218-22
Publication
First Author: Raij L
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Podocyte injury: the role of proteinuria, urinary plasminogen, and oxidative stress.
Volume: 311
Issue: 6
Pages: F1308-F1317
Publication
First Author: Weins A
Year: 2015
Journal: Am J Pathol
Title: Dendrin ablation prolongs life span by delaying kidney failure.
Volume: 185
Issue: 8
Pages: 2143-57
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: B
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: S
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: Lu
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: Li
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271728
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: SM
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: K
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1330403
Assay Type: Northern blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3809261
Age: postnatal adult
Specimen Label: T
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: B
Detected: false
Specimen Num: 1
GXD Expression        
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: H
Specimen Num: 2
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: S
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: Li
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: Lu
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: K
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3809257
Assay Type: Western blot
Annotation Date: 2008-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3809263
Age: postnatal adult
Specimen Label: T
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6287796
Assay Type: Northern blot
Annotation Date: 2019-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737518
Stage: TS18
Assay Id: MGI:6287797
Age: embryonic day 11.0
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6287796
Assay Type: Northern blot
Annotation Date: 2019-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:6287797
Age: embryonic day 17.0
Image: 1
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6287796
Assay Type: Northern blot
Annotation Date: 2019-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6287797
Age: postnatal adult
Image: 1
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6287803
Assay Type: Western blot
Annotation Date: 2019-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:6287807
Age: embryonic day 17.0
Image: 3
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6515563
Assay Type: Western blot
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:6515583
Age: embryonic day 17.0
Specimen Label: 211
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6515564
Assay Type: Western blot
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:6515584
Age: embryonic day 17.0
Specimen Label: 209
Detected: true
Specimen Num: 1