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Search results 1 to 100 out of 240 for Cd3d

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
396518 | CD3D
Type: gene
Organism: chicken
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Gene
915 | CD3D
Type: gene
Organism: human
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Gene
281053 | CD3D
Type: gene
Organism: cattle
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Gene
699582 | CD3D
Type: gene
Organism: macaque, rhesus
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Gene
25710 | Cd3d
Type: gene
Organism: rat
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Gene
479419 | CD3D
Type: gene
Organism: dog, domestic
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Gene
451584 | CD3D
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:88331 | Cd3d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR015485 | CD3D
Type: Family
Description: The closely related CD3 gamma and delta subunits constitute part of the invariant portion of the T cell receptor (TCR) complex. Both are transmembrane proteins with immunoglobulin-like domains in their extracellular regions. Each protein contains a single immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain that becomes phosphorylated upon ligation of the invariant TCR chains and provides binding sites for various downstream effectors [].
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DO Term
DOID:0060016 | CD3delta deficiency
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Protein
Q3U4T1
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
P04235
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
Q6P5P1
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
Q3U572
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
B0L6U8
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
Q3V3B4
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
A0N8K9
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: true
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Publication
14552840 | -
First Author: Pitcher LA
Year: 2003
Journal: Trends Immunol
Title: T-cell receptor signal transmission: who gives an ITAM?
Volume: 24
Issue: 10
Pages: 554-60
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Publication
9763617 | J:76991
First Author: Wang B
Year: 1998
Journal: J Exp Med
Title: Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytes.
Volume: 188
Issue: 7
Pages: 1375-80
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Publication
16888097 | J:140444
First Author: Fernández-Malavé E
Year: 2006
Journal: Blood
Title: Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse.
Volume: 108
Issue: 10
Pages: 3420-7
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Publication
27043412 | J:259151
First Author: Muñoz-Ruiz M
Year: 2016
Journal: Nat Immunol
Title: TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets.
Volume: 17
Issue: 6
Pages: 721-727
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Publication
17923503 | J:126111
First Author: Siegers GM
Year: 2007
Journal: J Exp Med
Title: Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
Volume: 204
Issue: 11
Pages: 2537-44
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Publication
20660709 | J:163269
First Author: Kim ST
Year: 2010
Journal: J Immunol
Title: Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.
Volume: 185
Issue: 5
Pages: 2951-9
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Publication
16418397 | J:118806
First Author: Hayes SM
Year: 2006
Journal: J Exp Med
Title: Stoichiometry of the murine gammadelta T cell receptor.
Volume: 203
Issue: 1
Pages: 47-52
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Publication
16412509 | J:108113
First Author: Pan Q
Year: 2006
Journal: Mol Immunol
Title: Different role for mouse and human CD3delta/epsilon heterodimer in preT cell receptor (preTCR) function: human CD3delta/epsilon heterodimer restores the defective preTCR function in CD3gamma- and CD3gammadelta-deficient mice.
Volume: 43
Issue: 11
Pages: 1741-50
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Publication
19342663 | J:147507
First Author: Brodeur JF
Year: 2009
Journal: J Immunol
Title: Critical and multiple roles for the CD3epsilon intracytoplasmic tail in double negative to double positive thymocyte differentiation.
Volume: 182
Issue: 8
Pages: 4844-53
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Protein Coding Gene
MGP_CAROLIEiJ_G0032133 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034380 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034539 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015002 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033271 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2939461 | J:49711
First Author: van den Elsen P
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex.
Volume: 83
Issue: 9
Pages: 2944-8
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Publication
2859526 | J:7832
First Author: van den Elsen P
Year: 1985
Journal: Nature
Title: Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein.
Volume: 314
Issue: 6011
Pages: 542-4
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Publication
9135151 | J:39925
First Author: Dave VP
Year: 1997
Journal: EMBO J
Title: CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.
Volume: 16
Issue: 6
Pages: 1360-70
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Publication
3857625 | J:7842
First Author: van den Elsen P
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Assignment of the gene coding for the T3-delta subunit of the T3-T-cell receptor complex to the long arm of human chromosome 11 and to mouse chromosome 9.
Volume: 82
Issue: 9
Pages: 2920-4
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Publication
8144959 | J:17604
First Author: Gupta A
Year: 1994
Journal: J Immunol
Title: CD3 delta enhancer. CREB interferes with the function of a murine CD3-delta A binding factor (M delta AF).
Volume: 152
Issue: 8
Pages: 3895-903
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_12
Specimen Label: euxassay_005684_12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_13
Specimen Label: euxassay_005684_13
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_14
Specimen Label: euxassay_005684_14
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_15
Specimen Label: euxassay_005684_15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_16
Specimen Label: euxassay_005684_16
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_17
Specimen Label: euxassay_005684_17
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:899331
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823730
Age: embryonic day 14.5
Image: euxassay_005684_18
Specimen Label: euxassay_005684_18
Detected: true
Specimen Num: 7
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Publication
36804959 | J:340980
First Author: Chora ÂF
Year: 2023
Journal: Immunity
Title: Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis.
Volume: 56
Issue: 3
Pages: 592-605.e8
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Publication
- | J:22096
First Author: Miller RD
Year: 1994
Journal: Mouse Genome
Title: A backcross panel typed for several immunoglobulin gene superfamily members on MMU9.
Volume: 92
Issue: 4
Pages: 694-695
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Publication
12215456 | J:113952
First Author: Doucey MA
Year: 2003
Journal: J Biol Chem
Title: CD3 delta establishes a functional link between the T cell receptor and CD8.
Volume: 278
Issue: 5
Pages: 3257-64
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Publication
2827170 | J:8994
First Author: Saito H
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.
Volume: 84
Issue: 24
Pages: 9131-4
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Publication
15459203 | J:95200
First Author: Pan Q
Year: 2004
Journal: J Biol Chem
Title: Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex.
Volume: 279
Issue: 49
Pages: 51068-74
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Publication
12444133 | J:112127
First Author: D'Oro U
Year: 2002
Journal: J Immunol
Title: Regulation of constitutive TCR internalization by the zeta-chain.
Volume: 169
Issue: 11
Pages: 6269-78
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Publication
8621641 | J:32707
First Author: van Leeuwen JE
Year: 1996
Journal: J Biol Chem
Title: Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes.
Volume: 271
Issue: 16
Pages: 9660-5
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Publication
12037605 | J:77494
First Author: Ropars A
Year: 2002
Journal: Immunogenetics
Title: Sequencing and expression of the CD3 gamma/delta mRNA in Pleurodeles waltl (urodele amphibian).
Volume: 54
Issue: 2
Pages: 130-8
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Publication
17368054 | J:120120
First Author: Kuhns MS
Year: 2007
Journal: Immunity
Title: Disruption of extracellular interactions impairs T cell receptor-CD3 complex stability and signaling.
Volume: 26
Issue: 3
Pages: 357-69
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Publication
11054779 | J:67839
First Author: Buck K
Year: 2000
Journal: Am J Med Genet
Title: Mapping quantitative trait loci that regulate sensitivity and tolerance to quinpirole, a dopamine mimetic selective for D(2)/D(3) receptors.
Volume: 96
Issue: 5
Pages: 696-705
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Publication
8327517 | J:13215
First Author: Ma Q
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.
Volume: 90
Issue: 13
Pages: 6350-4
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Publication
28441398 | J:246980
First Author: He T
Year: 2017
Journal: PLoS One
Title: The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury.
Volume: 12
Issue: 4
Pages: e0175522
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Publication
2971614 | J:9391
First Author: Evans GA
Year: 1988
Journal: Immunogenetics
Title: Molecular organization of the human CD3 gene family on chromosome 11q23.
Volume: 28
Issue: 5
Pages: 365-73
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Publication
8995487 | J:37353
First Author: Akao Y
Year: 1996
Journal: Cytogenet Cell Genet
Title: Identification and chromosome mapping of the mouse homologue of the human gene (DDX6) that encodes a putative RNA helicase of the DEAD box protein family.
Volume: 75
Issue: 1
Pages: 38-44
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Publication
7719941 | J:189418
First Author: Kearse KP
Year: 1995
Journal: Immunity
Title: TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes.
Volume: 2
Issue: 4
Pages: 391-9
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Publication
2522910 | J:9701
First Author: Letourneur F
Year: 1989
Journal: Immunogenetics
Title: The mouse CD3-gamma, -delta, and -epsilon genes reside within 50 kilobases on chromosome 9, whereas CD3-zeta maps to chromosome 1, band H.
Volume: 29
Issue: 4
Pages: 265-8
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Publication
18342007 | J:132996
First Author: He X
Year: 2008
Journal: Immunity
Title: CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.
Volume: 28
Issue: 3
Pages: 346-58
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Publication
19819936 | J:155472
First Author: Brodeur JF
Year: 2009
Journal: Int Immunol
Title: Expression of fully assembled TCR-CD3 complex on double positive thymocytes: synergistic role for the PRS and ER retention motifs in the intra-cytoplasmic tail of CD3epsilon.
Volume: 21
Issue: 12
Pages: 1317-27
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Publication
10323870 | J:55107
First Author: Tomita K
Year: 1999
Journal: Genes Dev
Title: The bHLH gene Hes1 is essential for expansion of early T cell precursors.
Volume: 13
Issue: 9
Pages: 1203-10
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Publication
2512252 | J:10147
First Author: Miller RD
Year: 1989
Journal: Immunogenetics
Title: Genetic mapping of mouse T3d and T3e between Apoa1 and Ncam.
Volume: 30
Issue: 6
Pages: 511-4
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Publication
8786135 | J:33856
First Author: Matsuda Y
Year: 1996
Journal: Genomics
Title: Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster.
Volume: 34
Issue: 3
Pages: 347-52
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Publication
10477673 | J:57074
First Author: Delassus S
Year: 1999
Journal: Blood
Title: Functional and molecular analysis of hematopoietic progenitors derived from the aorta-gonad-mesonephros region of the mouse embryo.
Volume: 94
Issue: 5
Pages: 1495-503
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Publication
8281015 | J:15639
First Author: Ryan AM
Year: 1993
Journal: Mamm Genome
Title: Chromosomal localization of uroplakin genes of cattle and mice.
Volume: 4
Issue: 11
Pages: 656-61
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Publication
35829816 | J:329324
First Author: Hosseini S
Year: 2022
Journal: Histochem Cell Biol
Title: The changing landscape of immune cells in the fetal mouse testis.
Volume: 158
Issue: 4
Pages: 345-368
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Publication
9208839 | J:41170
First Author: Wiest DL
Year: 1997
Journal: Immunity
Title: A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.
Volume: 6
Issue: 6
Pages: 663-71
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Publication
27575556 | J:309992
First Author: Vasilopoulou E
Year: 2016
Journal: Kidney Int
Title: Loss of endogenous thymosin β4 accelerates glomerular disease.
Volume: 90
Issue: 5
Pages: 1056-1070
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Publication
15245428 | J:91218
First Author: Sundberg JP
Year: 2004
Journal: J Invest Dermatol
Title: Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model.
Volume: 123
Issue: 2
Pages: 294-7
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Publication
1431091 | J:3170
First Author: Morse HC 3rd
Year: 1992
Journal: J Immunol
Title: Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.
Volume: 149
Issue: 10
Pages: 3129-34
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Publication
1794058 | J:459
First Author: Hearne CM
Year: 1991
Journal: Mamm Genome
Title: Additional microsatellite markers for mouse genome mapping.
Volume: 1
Issue: 4
Pages: 273-82
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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