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Search results 1 to 100 out of 167 for Cd46

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Hits by Strain

Type Details Score
Gene
4179 | CD46
Type: gene
Organism: human
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Gene
29333 | Cd46
Type: gene
Organism: rat
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Gene
469663 | CD46
Type: gene
Organism: chimpanzee
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Gene
280851 | CD46
Type: gene
Organism: cattle
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Gene
714082 | CD46
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR017341 | CD46
Type: Family
Description: This entry represents a group of membrane cofactor proteins (also known as CD46 or TLX). Human CD46 acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue []. Rat CD46 may be involved in the fusion of the spermatozoa with the oocyte during fertilization [].
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Protein Coding Gene
MGI:1203290 | Cd46
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25019227 | J:213630
First Author: Lyzogubov V
Year: 2014
Journal: Am J Pathol
Title: Complement regulatory protein CD46 protects against choroidal neovascularization in mice.
Volume: 184
Issue: 9
Pages: 2537-48
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Publication
15972677 | J:100593
First Author: Johansson L
Year: 2005
Journal: J Immunol
Title: Human-like immune responses in CD46 transgenic mice.
Volume: 175
Issue: 1
Pages: 433-40
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Publication
12640142 | J:82516
First Author: Inoue N
Year: 2003
Journal: Mol Cell Biol
Title: Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm.
Volume: 23
Issue: 7
Pages: 2614-22
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Publication
10843656 | -
First Author: Astier A
Year: 2000
Journal: J Immunol
Title: Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation.
Volume: 164
Issue: 12
Pages: 6091-5
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Publication
15215199 | -
First Author: Mizuno M
Year: 2004
Journal: Biol Reprod
Title: Rat membrane cofactor protein (MCP; CD46) is expressed only in the acrosome of developing and mature spermatozoa and mediates binding to immobilized activated C3.
Volume: 71
Issue: 4
Pages: 1374-83
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Publication
37579982 | J:341157
First Author: Geng X
Year: 2023
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The association between CD46 expression in B cells and the pathogenesis of airway allergy.
Volume: 1870
Issue: 1
Pages: 166845
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Publication
10627548 | J:59929
First Author: Evlashev A
Year: 2000
Journal: J Virol
Title: Productive measles virus brain infection and apoptosis in CD46 transgenic mice.
Volume: 74
Issue: 3
Pages: 1373-82
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Publication
27295359 | J:234294
First Author: Lyzogubov VV
Year: 2016
Journal: Am J Pathol
Title: The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration-Like Phenotype.
Volume: 186
Issue: 8
Pages: 2088-2104
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Publication
12055630 | J:324333
First Author: Marie JC
Year: 2002
Journal: Nat Immunol
Title: Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation.
Volume: 3
Issue: 7
Pages: 659-66
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Publication
11023821 | J:65538
 
First Author: Nomura M
Year: 2000
Journal: Biochem J
Title: Identification and characterization of a silencer regulatory element in the 3'-flanking region of the murine CD46 gene.
Volume: 351 Pt 2
Pages: 353-65
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Protein
O88174
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
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Protein
B2RWQ6
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
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Protein
A0A0R4J1X9
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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Gene
4182 | CD46P1
Type: gene
Organism: human
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Publication
11422193 | J:241699
First Author: Kemper C
Year: 2001
Journal: Clin Exp Immunol
Title: Membrane cofactor protein (MCP; CD46) expression in transgenic mice.
Volume: 124
Issue: 2
Pages: 180-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0015074 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1203290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016804 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028306 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015874 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9461505 | J:46287
 
First Author: Tsujimura A
Year: 1998
Journal: Biochem J
Title: Molecular cloning of a murine homologue of membrane cofactor protein (CD46): preferential expression in testicular germ cells.
Volume: 330 ( Pt 1)
Pages: 163-8
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Publication
10630288 | J:67188
First Author: Nomura M
Year: 1999
Journal: Immunogenetics
Title: Membrane and secretory forms of mouse membrane cofactor protein (CD46) generated from a single gene through alternative splicing.
Volume: 50
Issue: 5-6
Pages: 245-54
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Publication
10960475 | J:66001
First Author: Liszewski MK
Year: 2000
Journal: J Biol Chem
Title: Dissecting sites important for complement regulatory activity in membrane cofactor protein (MCP; CD46).
Volume: 275
Issue: 48
Pages: 37692-701
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GXD Expression
GXD Expression
     
Probe: MGI:5473668
Assay Type: Northern blot
Annotation Date: 2013-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5473710
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5473668
Assay Type: Northern blot
Annotation Date: 2013-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5473710
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5473668
Assay Type: Northern blot
Annotation Date: 2013-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5473710
Age: embryonic day 10.5
Specimen Label: 10.5 dpc Plac.
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5473668
Assay Type: Northern blot
Annotation Date: 2013-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5473710
Age: embryonic day 10.5
Specimen Label: 10.5 dpc Embr.
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5473681
Assay Type: RT-PCR
Annotation Date: 2013-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5473711
Age: embryonic day 10.5
Specimen Label: MCP-Placenta
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5473681
Assay Type: RT-PCR
Annotation Date: 2013-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5473711
Age: postnatal adult
Specimen Label: MCP-Testis
Detected: true
Specimen Num: 5
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Publication
12914820 | J:85193
First Author: Turnberg D
Year: 2003
Journal: Mol Immunol
Title: The regulation of the complement system: insights from genetically-engineered mice.
Volume: 40
Issue: 2-4
Pages: 145-53
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Publication
33688034 | J:303467
 
First Author: Lu M
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike.
Volume: 118
Issue: 12
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Publication
21106855 | J:168736
First Author: Delano MJ
Year: 2011
Journal: J Immunol
Title: Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
Volume: 186
Issue: 1
Pages: 195-202
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Publication
9799332 | J:51088
First Author: Miwa T
Year: 1998
Journal: Immunogenetics
Title: Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.
Volume: 48
Issue: 6
Pages: 363-71
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Publication
12869763 | J:110283
First Author: Johansson L
Year: 2003
Journal: Science
Title: CD46 in meningococcal disease.
Volume: 301
Issue: 5631
Pages: 373-5
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Publication
14670299 | J:86999
First Author: Mao D
Year: 2003
Journal: Immunity
Title: Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.
Volume: 19
Issue: 6
Pages: 813-22
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Publication
16002709 | J:100702
First Author: Chen Y
Year: 2005
Journal: J Immunol
Title: Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.
Volume: 175
Issue: 2
Pages: 1080-9
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Gene
365577 | Cd46l1
Type: gene
Organism: rat
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
19737905 | J:154121
First Author: Matsui H
Year: 2009
Journal: Infect Immun
Title: CD46 transgenic mouse model of necrotizing fasciitis caused by Streptococcus pyogenes infection.
Volume: 77
Issue: 11
Pages: 4806-14
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Gene
609365 | LOC609365
Type: gene
Organism: dog, domestic
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Publication
21573156 | J:172427
First Author: Grumelli S
Year: 2011
Journal: PLoS One
Title: CD46 protects against chronic obstructive pulmonary disease.
Volume: 6
Issue: 5
Pages: e18785
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Publication
9791016 | J:127512
First Author: Blixenkrone-Møller M
Year: 1998
Journal: Virology
Title: Role of CD46 in measles virus infection in CD46 transgenic mice.
Volume: 249
Issue: 2
Pages: 238-48
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Publication
24574405 | J:214429
First Author: Reynaud JM
Year: 2014
Journal: J Virol
Title: Human herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via Toll-like receptor 9.
Volume: 88
Issue: 10
Pages: 5421-36
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Publication
9079815 | J:39002
First Author: Thorley BR
Year: 1997
Journal: Eur J Immunol
Title: Transgenic expression of a CD46 (membrane cofactor protein) minigene: studies of xenotransplantation and measles virus infection.
Volume: 27
Issue: 3
Pages: 726-34
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Publication
32581096 | J:302340
 
First Author: Feng Y
Year: 2020
Journal: J Virol
Title: Human Desmoglein-2 and Human CD46 Mediate Human Adenovirus Type 55 Infection, but Human Desmoglein-2 Plays the Major Roles.
Volume: 94
Issue: 17
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Allele
Cd46<tm1Atk> | MGI:5586970
Name: CD46 antigen, complement regulatory protein; targeted mutation 1, John P Atkinson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd46<+> | MGI:2435103
   
Name: CD46 antigen, complement regulatory protein; wild type
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Transgene
MGI:3688751 | Tg(CD46)2Gsv
Type: transgene
Organism: mouse, laboratory
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Allele
Cd46<em1(IMPC)H> | MGI:6435660
Name: CD46 antigen, complement regulatory protein; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd46<em1Cya> | MGI:7792588
Name: CD46 antigen, complement regulatory protein; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd46<em2Cya> | MGI:7792589
Name: CD46 antigen, complement regulatory protein; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(CD46)2Gsv | MGI:3688752
Name: transgene insertion 2, Frank Grosveld
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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