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Search results 1 to 100 out of 492 for Cd47

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0.021s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: Leukocyte surface antigen CD47 (also known as integrin-associated protein, IAP) is a widely expressed membrane protein with multiple functions in immunological and neuronal processes. For example, CD47-induces caspase-independent cell death which may be mediated by cytoskeleton reorganisation []. In red blood cells, CD47 acts like a marker of self by ligating the macrophage inhibitory receptor signal regulatory protein alpha []. The protein can also act as a thrombospondin receptor [].This entry also includes a group of CD-47-like proteins found in poxviruses (Poxviridae) such as protein A38 [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Oldenborg PA
Year: 2002
Journal: Blood
Title: Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice.
Volume: 99
Issue: 10
Pages: 3500-4
Protein
Organism: Mus musculus
Length: 258  
Fragment?: false
Protein
Organism: Mus musculus
Length: 271  
Fragment?: false
Protein
Organism: Mus musculus
Length: 278  
Fragment?: false
Protein
Organism: Mus musculus
Length: 291  
Fragment?: false
Protein
Organism: Mus musculus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus
Length: 267  
Fragment?: false
Protein
Organism: Mus musculus
Length: 321  
Fragment?: false
Protein
Organism: Mus musculus
Length: 303  
Fragment?: false
Protein
Organism: Mus musculus
Length: 303  
Fragment?: false
Protein
Organism: Mus musculus
Length: 303  
Fragment?: false
Publication
First Author: El-Rashid M
Year: 2019
Journal: FASEB J
Title: CD47 limits autophagy to promote acute kidney injury.
Volume: 33
Issue: 11
Pages: 12735-12749
Publication  
First Author: Norman-Burgdolf H
Year: 2020
Journal: Biol Open
Title: CD47 differentially regulates white and brown fat function.
Volume: 9
Issue: 12
Publication
First Author: Li Z
Year: 2002
Journal: J Cell Biol
Title: Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.
Volume: 157
Issue: 3
Pages: 509-19
Publication
First Author: Uluçkan O
Year: 2009
Journal: Cancer Res
Title: CD47 regulates bone mass and tumor metastasis to bone.
Volume: 69
Issue: 7
Pages: 3196-204
Publication
First Author: Sanderson CM
Year: 1996
Journal: J Virol
Title: Overexpression of the vaccinia virus A38L integral membrane protein promotes Ca2+ influx into infected cells.
Volume: 70
Issue: 2
Pages: 905-14
Publication  
First Author: Ghimire K
Year: 2020
Journal: Cells
Title: CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis.
Volume: 9
Issue: 7
Publication
First Author: Jin G
Year: 2009
Journal: Exp Neurol
Title: CD47 gene knockout protects against transient focal cerebral ischemia in mice.
Volume: 217
Issue: 1
Pages: 165-70
Publication  
First Author: Zhao S
Year: 2017
Journal: Neurosci Lett
Title: CD47 deficiency improves neurological outcomes of traumatic brain injury in mice.
Volume: 643
Pages: 125-130
Publication
First Author: Jaiswal S
Year: 2009
Journal: Cell
Title: CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.
Volume: 138
Issue: 2
Pages: 271-85
Publication
First Author: Han MH
Year: 2012
Journal: J Exp Med
Title: Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice.
Volume: 209
Issue: 7
Pages: 1325-34
Publication
First Author: Su X
Year: 2008
Journal: J Immunol
Title: CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
Volume: 180
Issue: 10
Pages: 6947-53
Publication
First Author: Van VQ
Year: 2006
Journal: EMBO J
Title: Expression of the self-marker CD47 on dendritic cells governs their trafficking to secondary lymphoid organs.
Volume: 25
Issue: 23
Pages: 5560-8
Publication
First Author: Olsson M
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Dose-dependent inhibitory effect of CD47 in macrophage uptake of IgG-opsonized murine erythrocytes.
Volume: 352
Issue: 1
Pages: 193-7
Publication
First Author: Lehrman EK
Year: 2018
Journal: Neuron
Title: CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.
Volume: 100
Issue: 1
Pages: 120-134.e6
Publication  
First Author: Maimaitiyiming H
Year: 2015
Journal: Sci Rep
Title: CD47 deficiency protects mice from diet-induced obesity and improves whole body glucose tolerance and insulin sensitivity.
Volume: 5
Pages: 8846
Publication
First Author: Fortin G
Year: 2009
Journal: J Exp Med
Title: A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells.
Volume: 206
Issue: 9
Pages: 1995-2011
Publication
First Author: Navarathna DH
Year: 2015
Journal: PLoS One
Title: CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis.
Volume: 10
Issue: 5
Pages: e0128220
Publication
First Author: Banerjee R
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite.
Volume: 112
Issue: 10
Pages: 3062-7
Publication
First Author: Nilsson A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: CD47 promotes both phosphatidylserine-independent and phosphatidylserine-dependent phagocytosis of apoptotic murine thymocytes by non-activated macrophages.
Volume: 387
Issue: 1
Pages: 58-63
Publication  
First Author: Nath PR
Year: 2018
Journal: Front Immunol
Title: CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus.
Volume: 9
Pages: 2985
Publication
First Author: Lamy L
Year: 2007
Journal: J Immunol
Title: Interactions between CD47 and thrombospondin reduce inflammation.
Volume: 178
Issue: 9
Pages: 5930-9
Publication
First Author: Bian Z
Year: 2013
Journal: J Immunol
Title: CD47 deficiency does not impede polymorphonuclear neutrophil transmigration but attenuates granulopoiesis at the postacute stage of colitis.
Volume: 190
Issue: 1
Pages: 411-7
Publication
First Author: Stefanidakis M
Year: 2008
Journal: Blood
Title: Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro.
Volume: 112
Issue: 4
Pages: 1280-9
Publication
First Author: Olsson M
Year: 2008
Journal: Blood
Title: CD47 on experimentally senescent murine RBCs inhibits phagocytosis following Fcgamma receptor-mediated but not scavenger receptor-mediated recognition by macrophages.
Volume: 112
Issue: 10
Pages: 4259-67
Publication
First Author: Azcutia V
Year: 2012
Journal: J Immunol
Title: Endothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivo.
Volume: 189
Issue: 5
Pages: 2553-62
Publication
First Author: Olsson M
Year: 2005
Journal: Blood
Title: Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia.
Volume: 105
Issue: 9
Pages: 3577-82
Publication
First Author: Bouguermouh S
Year: 2008
Journal: J Immunol
Title: CD47 expression on T cell is a self-control negative regulator of type 1 immune response.
Volume: 180
Issue: 12
Pages: 8073-82
Publication
First Author: Lee YT
Year: 2016
Journal: J Virol
Title: CD47 Plays a Role as a Negative Regulator in Inducing Protective Immune Responses to Vaccination against Influenza Virus.
Volume: 90
Issue: 15
Pages: 6746-58
Publication
First Author: Maile LA
Year: 2011
Journal: J Bone Miner Res
Title: An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.
Volume: 26
Issue: 9
Pages: 2068-81
Publication      
First Author: Song C
Year: 2017
Journal: MGI Direct Data Submission
Title: Direct data submission for Cd47 alleles
Publication
First Author: Murata T
Year: 2006
Journal: J Neurosci
Title: CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42.
Volume: 26
Issue: 48
Pages: 12397-407
Publication
First Author: Isenberg JS
Year: 2009
Journal: Matrix Biol
Title: Thrombospondin-1 and CD47 regulate blood pressure and cardiac responses to vasoactive stress.
Volume: 28
Issue: 2
Pages: 110-9
Publication  
First Author: Soto-Pantoja DR
Year: 2014
Journal: Matrix Biol
Title: Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice.
Volume: 37
Pages: 25-34
Publication
First Author: Hagnerud S
Year: 2006
Journal: J Immunol
Title: Deficit of CD47 results in a defect of marginal zone dendritic cells, blunted immune response to particulate antigen and impairment of skin dendritic cell migration.
Volume: 176
Issue: 10
Pages: 5772-8
Publication
First Author: Myers SA
Year: 2011
Journal: Neurobiol Dis
Title: CD47 knockout mice exhibit improved recovery from spinal cord injury.
Volume: 42
Issue: 1
Pages: 21-34
Publication
First Author: Wang H
Year: 2010
Journal: J Immunol
Title: CD47 is required for suppression of allograft rejection by donor-specific transfusion.
Volume: 184
Issue: 7
Pages: 3401-7
Publication
First Author: Van VQ
Year: 2008
Journal: J Immunol
Title: Cutting edge: CD47 controls the in vivo proliferation and homeostasis of peripheral CD4+ CD25+ Foxp3+ regulatory T cells that express CD103.
Volume: 181
Issue: 8
Pages: 5204-8
Publication
First Author: Wang F
Year: 2020
Journal: Aging Cell
Title: Aging-associated changes in CD47 arrangement and interaction with thrombospondin-1 on red blood cells visualized by super-resolution imaging.
Volume: 19
Issue: 10
Pages: e13224
Publication
First Author: Mateo V
Year: 2002
Journal: Blood
Title: Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization.
Volume: 100
Issue: 8
Pages: 2882-90
Publication
First Author: Marschinke F
Year: 2012
Journal: PLoS One
Title: The absence of CD47 promotes nerve fiber growth from cultured ventral mesencephalic dopamine neurons.
Volume: 7
Issue: 9
Pages: e45218
Publication
First Author: Reed M
Year: 2019
Journal: Nat Commun
Title: Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo.
Volume: 10
Issue: 1
Pages: 5004
Publication  
First Author: Gitik M
Year: 2011
Journal: J Neuroinflammation
Title: Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.
Volume: 8
Pages: 24
Publication
First Author: Guimont-Desrochers F
Year: 2009
Journal: Int Immunol
Title: Absence of CD47 in vivo influences thymic dendritic cell subset proportions but not negative selection of thymocytes.
Volume: 21
Issue: 2
Pages: 167-77
Publication
First Author: Isenberg JS
Year: 2008
Journal: Am J Pathol
Title: Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.
Volume: 173
Issue: 4
Pages: 1100-12
Publication
First Author: Shi L
Year: 2015
Journal: J Pathol
Title: CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production.
Volume: 237
Issue: 3
Pages: 285-95
Publication
First Author: Hsieh CP
Year: 2015
Journal: Dev Neurobiol
Title: Deficits in cerebellar granule cell development and social interactions in CD47 knockout mice.
Volume: 75
Issue: 5
Pages: 463-84
Publication
First Author: Oldenborg PA
Year: 2000
Journal: Science
Title: Role of CD47 as a marker of self on red blood cells.
Volume: 288
Issue: 5473
Pages: 2051-4
Publication
First Author: Chin AC
Year: 2009
Journal: J Immunol
Title: CD47 and TLR-2 cross-talk regulates neutrophil transmigration.
Volume: 183
Issue: 9
Pages: 5957-63
Publication
First Author: Koskinen C
Year: 2013
Journal: J Biol Chem
Title: Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling.
Volume: 288
Issue: 41
Pages: 29333-44
Publication  
First Author: Zuo Z
Year: 2019
Journal: Oxid Med Cell Longev
Title: CD47 Deficiency Attenuates Isoproterenol-Induced Cardiac Remodeling in Mice.
Volume: 2019
Pages: 7121763
Publication
First Author: Julovi SM
Year: 2020
Journal: Lab Invest
Title: Blocking thrombospondin-1 signaling via CD47 mitigates renal interstitial fibrosis.
Volume: 100
Issue: 9
Pages: 1184-1196
Publication  
First Author: Tal MC
Year: 2020
Journal: mBio
Title: Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition.
Volume: 11
Issue: 3
Publication
First Author: He Y
Year: 2020
Journal: Sci Rep
Title: CD47 is a negative regulator of intestinal epithelial cell self-renewal following DSS-induced experimental colitis.
Volume: 10
Issue: 1
Pages: 10180
Publication  
First Author: Wang Q
Year: 2019
Journal: JCI Insight
Title: Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis.
Volume: 4
Issue: 18
Publication
First Author: Edris B
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma.
Volume: 109
Issue: 17
Pages: 6656-61
Publication
First Author: Rogers NM
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management.
Volume: 303
Issue: 8
Pages: F1117-25
Publication
First Author: Soto-Pantoja DR
Year: 2014
Journal: Cancer Res
Title: CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapy.
Volume: 74
Issue: 23
Pages: 6771-83
Publication
First Author: Kim JI
Year: 2018
Journal: Lab Anim Res
Title: CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice.
Volume: 34
Issue: 4
Pages: 302-310
Publication
First Author: Morrissey MA
Year: 2020
Journal: Immunity
Title: CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.
Volume: 53
Issue: 2
Pages: 290-302.e6
Publication  
First Author: Tao HC
Year: 2020
Journal: Front Immunol
Title: CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism.
Volume: 11
Pages: 148
Publication
First Author: Bauer PM
Year: 2012
Journal: Cardiovasc Res
Title: Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.
Volume: 93
Issue: 4
Pages: 682-93
Publication
First Author: Kusakari S
Year: 2008
Journal: J Cell Sci
Title: Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system.
Volume: 121
Issue: Pt 8
Pages: 1213-23
Publication
First Author: Isenberg JS
Year: 2006
Journal: J Biol Chem
Title: CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1.
Volume: 281
Issue: 36
Pages: 26069-80
Publication
First Author: Lindberg FP
Year: 1993
Journal: J Cell Biol
Title: Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding.
Volume: 123
Issue: 2
Pages: 485-96
Publication
First Author: Lundberg P
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction.
Volume: 352
Issue: 2
Pages: 444-8
Publication
First Author: Tada K
Year: 2003
Journal: J Immunol
Title: Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1.
Volume: 171
Issue: 11
Pages: 5718-26
Publication
First Author: Rebres RA
Year: 2001
Journal: J Biol Chem
Title: Normal ligand binding and signaling by CD47 (integrin-associated protein) requires a long range disulfide bond between the extracellular and membrane-spanning domains.
Volume: 276
Issue: 37
Pages: 34607-16
Publication
First Author: Engelbertsen D
Year: 2019
Journal: Sci Rep
Title: Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.
Volume: 9
Issue: 1
Pages: 10608
Publication
First Author: Van VQ
Year: 2012
Journal: J Immunol
Title: CD47(high) expression on CD4 effectors identifies functional long-lived memory T cell progenitors.
Volume: 188
Issue: 9
Pages: 4249-55
Publication
First Author: Koshimizu H
Year: 2014
Journal: PLoS One
Title: Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice.
Volume: 9
Issue: 2
Pages: e89584
Publication
First Author: Csányi G
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.
Volume: 32
Issue: 12
Pages: 2966-73
Publication
First Author: Westlund J
Year: 2012
Journal: Immunology
Title: CD47-deficient mice have decreased production of intestinal IgA following oral immunization but a maintained capacity to induce oral tolerance.
Volume: 135
Issue: 3
Pages: 236-44
Publication
First Author: Van VQ
Year: 2012
Journal: PLoS One
Title: CD47(low) status on CD4 effectors is necessary for the contraction/resolution of the immune response in humans and mice.
Volume: 7
Issue: 8
Pages: e41972
Publication
First Author: Wong AS
Year: 2014
Journal: J Immunol
Title: Polymorphism in the innate immune receptor SIRPα controls CD47 binding and autoimmunity in the nonobese diabetic mouse.
Volume: 193
Issue: 10
Pages: 4833-44
Publication
First Author: Chang HP
Year: 1999
Journal: Learn Mem
Title: Impaired memory retention and decreased long-term potentiation in integrin-associated protein-deficient mice.
Volume: 6
Issue: 5
Pages: 448-57
Publication
First Author: Ball SL
Year: 2001
Journal: Neurosci Lett
Title: Electroretinograms remain normal in mice lacking a synapse associated protein.
Volume: 298
Issue: 2
Pages: 111-4
Publication
First Author: Verdrengh M
Year: 1999
Journal: Microbes Infect
Title: Integrin-associated protein (IAP)-deficient mice are less susceptible to developing Staphylococcus aureus-induced arthritis.
Volume: 1
Issue: 10
Pages: 745-51
Publication
First Author: Frazier EP
Year: 2011
Journal: Matrix Biol
Title: Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47.
Volume: 30
Issue: 2
Pages: 154-61
Publication
First Author: Wu J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity.
Volume: 115
Issue: 26
Pages: 6786-6791
Publication
First Author: Jackson A
Year: 2010
Journal: J Immunol
Title: Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
Volume: 185
Issue: 10
Pages: 6198-204
Publication
First Author: Bauer EM
Year: 2010
Journal: Cardiovasc Res
Title: Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation.
Volume: 88
Issue: 3
Pages: 471-81
Publication
First Author: Koduru SV
Year: 2018
Journal: J Biol Chem
Title: The contribution of cross-talk between the cell-surface proteins CD36 and CD47-TSP-1 in osteoclast formation and function.
Volume: 293
Issue: 39
Pages: 15055-15069
Publication
First Author: Rogers NM
Year: 2017
Journal: Cardiovasc Res
Title: TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.
Volume: 113
Issue: 1
Pages: 15-29
Publication
First Author: Capo C
Year: 1999
Journal: J Immunol
Title: Subversion of monocyte functions by coxiella burnetii: impairment of the cross-talk between alphavbeta3 integrin and CR3.
Volume: 163
Issue: 11
Pages: 6078-85
Publication
First Author: Johansen ML
Year: 2007
Journal: J Biol Chem
Title: Dual regulation of SIRPalpha phosphorylation by integrins and CD47.
Volume: 282
Issue: 33
Pages: 24219-30