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Search results 1 to 100 out of 894 for Cd86

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
942 | CD86
Type: gene
Organism: human
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Gene
414345 | CD86
Type: gene
Organism: cattle
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Gene
427944 | CD86
Type: gene
Organism: chicken
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Gene
714390 | CD86
Type: gene
Organism: macaque, rhesus
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Gene
key_25584 | CD86
Type: gene
Organism: rabbit, European
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Gene
100486350 | cd86
Type: gene
Organism: frog, western clawed
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Gene
56822 | Cd86
Type: gene
Organism: rat
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Gene
470900 | CD86
Type: gene
Organism: chimpanzee
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Gene
403764 | CD86
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:101773 | Cd86
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
A0A0X9RAD7
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Publication
17641017 | J:149951
First Author: Kin NW
Year: 2007
Journal: J Immunol
Title: CD86 regulates IgG1 production via a CD19-dependent mechanism.
Volume: 179
Issue: 3
Pages: 1516-23
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Publication
17947667 | J:138692
First Author: Thomas IJ
Year: 2007
Journal: J Immunol
Title: CD86 has sustained costimulatory effects on CD8 T cells.
Volume: 179
Issue: 9
Pages: 5936-46
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Publication
23241883 | J:191189
First Author: Lucas CR
Year: 2013
Journal: J Immunol
Title: Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.
Volume: 190
Issue: 2
Pages: 723-36
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Publication
16014035 | J:114308
First Author: Odobasic D
Year: 2005
Journal: Kidney Int
Title: CD80 and CD86 costimulatory molecules regulate crescentic glomerulonephritis by different mechanisms.
Volume: 68
Issue: 2
Pages: 584-94
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Publication
22371880 | J:185002
First Author: Shimazu T
Year: 2012
Journal: Blood
Title: CD86 is expressed on murine hematopoietic stem cells and denotes lymphopoietic potential.
Volume: 119
Issue: 21
Pages: 4889-97
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Publication
22307040 | J:323159
First Author: Gu P
Year: 2012
Journal: Cell Mol Immunol
Title: Trogocytosis of CD80 and CD86 by induced regulatory T cells.
Volume: 9
Issue: 2
Pages: 136-46
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Publication
12516542 | J:292872
First Author: Moro M
Year: 2002
Journal: Eur J Immunol
Title: Blockade of CD86 in BALB/c mice infected with Leishmania major does not prevent the expansion of low avidity T cells.
Volume: 32
Issue: 12
Pages: 3566-75
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Publication
21849678 | J:179234
First Author: Baravalle G
Year: 2011
Journal: J Immunol
Title: Ubiquitination of CD86 is a key mechanism in regulating antigen presentation by dendritic cells.
Volume: 187
Issue: 6
Pages: 2966-73
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Publication
19672303 | J:152470
First Author: Nolan A
Year: 2009
Journal: PLoS One
Title: Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis.
Volume: 4
Issue: 8
Pages: e6600
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Publication
10630300 | J:65824
First Author: Yang S
Year: 1999
Journal: Immunogenetics
Title: New forms of dog CD80 and CD86 transcripts that encode secreted B7 molecules.
Volume: 50
Issue: 5-6
Pages: 349-53
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Publication
10878340 | J:120527
First Author: Kasprowicz DJ
Year: 2000
Journal: J Immunol
Title: Stimulation of the B cell receptor, CD86 (B7-2), and the beta 2-adrenergic receptor intrinsically modulates the level of IgG1 and IgE produced per B cell.
Volume: 165
Issue: 2
Pages: 680-90
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GO Term
GO:0150140 | regulation of CD86 production
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Publication
11726649 | J:75069
First Author: Suvas S
Year: 2002
Journal: J Biol Chem
Title: Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma.
Volume: 277
Issue: 10
Pages: 7766-75
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Publication
7513726 | J:18042
First Author: Chen C
Year: 1994
Journal: J Immunol
Title: Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule.
Volume: 152
Issue: 10
Pages: 4929-36
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Publication
17804511 | J:129927
First Author: Thebeau LG
Year: 2007
Journal: J Virol
Title: B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient mice.
Volume: 81
Issue: 22
Pages: 12200-9
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Publication
19299714 | J:147126
First Author: Ahlmann M
Year: 2009
Journal: J Immunol
Title: The cyclic AMP response element modulator {alpha} suppresses CD86 expression and APC function.
Volume: 182
Issue: 7
Pages: 4167-74
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Publication
16709832 | J:131798
First Author: Kin NW
Year: 2006
Journal: J Immunol
Title: CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase C gamma 2/protein kinase C alpha beta signaling pathways.
Volume: 176
Issue: 11
Pages: 6727-35
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Publication
21119111 | J:169576
First Author: Kanada S
Year: 2011
Journal: Blood
Title: Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.
Volume: 117
Issue: 7
Pages: 2211-22
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Publication
7499829 | J:30027
First Author: Borriello F
Year: 1995
Journal: J Immunol
Title: Differential expression of alternate mB7-2 transcripts.
Volume: 155
Issue: 12
Pages: 5490-7
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Publication
30468863 | J:274795
 
First Author: Huehnchen P
Year: 2019
Journal: Neurobiol Dis
Title: High salt diet ameliorates functional, electrophysiological and histological characteristics of murine spontaneous autoimmune polyneuropathy.
Volume: 124
Pages: 240-247
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Publication
8943044 | J:37051
First Author: Hancock WW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection.
Volume: 93
Issue: 24
Pages: 13967-72
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Publication
30010888 | J:266678
First Author: Xiao Y
Year: 2018
Journal: Int Immunol
Title: Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells.
Volume: 30
Issue: 10
Pages: 457-470
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Publication
17785819 | J:152043
First Author: Liu Q
Year: 2007
Journal: J Immunol
Title: The role of B cells in the development of CD4 effector T cells during a polarized Th2 immune response.
Volume: 179
Issue: 6
Pages: 3821-30
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Publication
10201938 | J:119772
First Author: Greenwald RJ
Year: 1999
Journal: J Immunol
Title: B7-2 is required for the progression but not the initiation of the type 2 immune response to a gastrointestinal nematode parasite.
Volume: 162
Issue: 7
Pages: 4133-9
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Publication
29615658 | J:263066
First Author: Gao T
Year: 2018
Journal: Sci Rep
Title: Systemic IGF-1 gene delivery by rAAV9 improves spontaneous autoimmune peripheral polyneuropathy (SAPP).
Volume: 8
Issue: 1
Pages: 5408
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Publication
23850635 | J:244258
 
First Author: Bour-Jordan H
Year: 2013
Journal: J Autoimmun
Title: Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.
Volume: 45
Pages: 58-67
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Publication
11535635 | J:71352
First Author: Salomon B
Year: 2001
Journal: J Exp Med
Title: Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice.
Volume: 194
Issue: 5
Pages: 677-84
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Publication
28215575 | J:261145
 
First Author: Dong C
Year: 2017
Journal: Exp Neurol
Title: Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathy.
Volume: 292
Pages: 35-45
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Publication
17475851 | J:146121
First Author: Yadav D
Year: 2007
Journal: J Immunol
Title: B7-2 regulates survival, phenotype, and function of APCs.
Volume: 178
Issue: 10
Pages: 6236-41
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Publication
19265158 | J:145915
First Author: Bhatt K
Year: 2009
Journal: J Immunol
Title: B7 costimulation is critical for host control of chronic Mycobacterium tuberculosis infection.
Volume: 182
Issue: 6
Pages: 3793-800
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Publication
12835481 | J:84466
First Author: Sugita S
Year: 2003
Journal: J Exp Med
Title: Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4.
Volume: 198
Issue: 1
Pages: 161-71
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Publication
8683128 | J:34227
First Author: Kariv I
Year: 1996
Journal: J Immunol
Title: Analysis of the site of interaction of CD28 with its counter-receptors CD80 and CD86 and correlation with function.
Volume: 157
Issue: 1
Pages: 29-38
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Publication
10679081 | J:60567
First Author: Dahlén E
Year: 2000
Journal: J Immunol
Title: Low CD86 expression in the nonobese diabetic mouse results in the impairment of both T cell activation and CTLA-4 up-regulation.
Volume: 164
Issue: 5
Pages: 2444-56
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Publication
9250865 | J:42172
First Author: Reeves RH
Year: 1997
Journal: Mamm Genome
Title: The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3.
Volume: 8
Issue: 8
Pages: 581-2
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Publication
24470500 | J:209825
First Author: Attridge K
Year: 2014
Journal: J Immunol
Title: IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells.
Volume: 192
Issue: 5
Pages: 2195-201
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Publication
21220452 | J:176856
First Author: Tze LE
Year: 2011
Journal: J Exp Med
Title: CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.
Volume: 208
Issue: 1
Pages: 149-65
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GO Term
GO:0150142 | positive regulation of CD86 production
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GO Term
GO:0150141 | negative regulation of CD86 production
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Publication
15356107 | J:92756
First Author: Yadav D
Year: 2004
Journal: J Immunol
Title: B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets.
Volume: 173
Issue: 6
Pages: 3631-9
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Publication
32572241 | J:297806
First Author: Tanaka S
Year: 2020
Journal: Nat Immunol
Title: Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.
Volume: 21
Issue: 8
Pages: 950-961
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Publication
17911596 | J:153036
First Author: O'Neill SK
Year: 2007
Journal: J Immunol
Title: Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis.
Volume: 179
Issue: 8
Pages: 5109-16
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Publication
12055251 | J:123794
First Author: Ekkens MJ
Year: 2002
Journal: J Immunol
Title: Memory Th2 effector cells can develop in the absence of B7-1/B7-2, CD28 interactions, and effector Th cells after priming with an intestinal nematode parasite.
Volume: 168
Issue: 12
Pages: 6344-51
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Publication
23248264 | J:191718
First Author: Corse E
Year: 2013
Journal: J Immunol
Title: Cutting edge: chronic inflammatory liver disease in mice expressing a CD28-specific ligand.
Volume: 190
Issue: 2
Pages: 526-30
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Publication
21126972 | J:179473
First Author: Vinh A
Year: 2010
Journal: Circulation
Title: Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension.
Volume: 122
Issue: 24
Pages: 2529-37
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Publication
15843526 | J:98420
First Author: Loser K
Year: 2005
Journal: J Immunol
Title: An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice.
Volume: 174
Issue: 9
Pages: 5298-305
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Publication
24099792 | J:205997
First Author: Bhatt K
Year: 2013
Journal: Cell Immunol
Title: Equivalent functions for B7.1 and B7.2 costimulation in mediating host resistance to Mycobacterium tuberculosis.
Volume: 285
Issue: 1-2
Pages: 69-75
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Publication
11120800 | J:66171
First Author: Santra S
Year: 2000
Journal: J Immunol
Title: Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses.
Volume: 165
Issue: 12
Pages: 6791-5
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Publication
18453575 | J:134959
First Author: Perez N
Year: 2008
Journal: J Immunol
Title: Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+) -adaptive regulatory T cell generation.
Volume: 180
Issue: 10
Pages: 6566-76
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Publication
7504059 | J:15724
First Author: Freeman GJ
Year: 1993
Journal: J Exp Med
Title: Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production.
Volume: 178
Issue: 6
Pages: 2185-92
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Publication
18802089 | J:142741
First Author: Tseng SY
Year: 2008
Journal: J Immunol
Title: T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta.
Volume: 181
Issue: 7
Pages: 4852-63
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Publication
15385483 | J:93124
First Author: Garcia CA
Year: 2004
Journal: Infect Immun
Title: Role of B7 costimulatory molecules in mediating systemic and mucosal antibody responses to attenuated Salmonella enterica serovar Typhimurium and its cloned antigen.
Volume: 72
Issue: 10
Pages: 5824-31
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Publication
10590107 | J:125985
First Author: McAdam AJ
Year: 2000
Journal: J Virol
Title: B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus.
Volume: 74
Issue: 1
Pages: 203-8
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Publication
9075931 | J:39089
First Author: Borriello F
Year: 1997
Journal: Immunity
Title: B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation.
Volume: 6
Issue: 3
Pages: 303-13
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Publication
21441451 | J:172856
First Author: Salek-Ardakani S
Year: 2011
Journal: J Immunol
Title: B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus.
Volume: 186
Issue: 9
Pages: 5294-303
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Publication
10696062 | J:114244
First Author: Mark DA
Year: 2000
Journal: Am J Respir Cell Mol Biol
Title: B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness.
Volume: 22
Issue: 3
Pages: 265-71
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Publication
14742503 | J:87827
First Author: Zhang P
Year: 2004
Journal: Infect Immun
Title: Role of B7 costimulatory molecules in immune responses and T-helper cell differentiation in response to recombinant HagB from Porphyromonas gingivalis.
Volume: 72
Issue: 2
Pages: 637-44
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Publication
19050296 | J:142046
First Author: Kim HJ
Year: 2008
Journal: J Immunol
Title: Targeting of myelin protein zero in a spontaneous autoimmune polyneuropathy.
Volume: 181
Issue: 12
Pages: 8753-60
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Publication
15470046 | J:93703
First Author: Lohr J
Year: 2004
Journal: J Immunol
Title: Role of B7 in T cell tolerance.
Volume: 173
Issue: 8
Pages: 5028-35
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Publication
15522961 | J:98140
First Author: Anderson BE
Year: 2005
Journal: Blood
Title: Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ.
Volume: 105
Issue: 5
Pages: 2227-34
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Publication
12207354 | J:78992
First Author: Jabs C
Year: 2002
Journal: Eur J Immunol
Title: Genetic background determines the requirement for B7 costimulation in induction of autoimmunity.
Volume: 32
Issue: 9
Pages: 2687-97
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Publication
21040905 | J:167013
First Author: Fuse S
Year: 2011
Journal: Cell Immunol
Title: Differential requirements for CD80/86-CD28 costimulation in primary and memory CD4 T cell responses to vaccinia virus.
Volume: 266
Issue: 2
Pages: 130-4
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Publication
15528348 | J:94288
First Author: Meyer zum Bueschenfelde CO
Year: 2004
Journal: J Immunol
Title: Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells.
Volume: 173
Issue: 10
Pages: 6119-24
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Publication
31712675 | J:287317
First Author: Kim YH
Year: 2019
Journal: Sci Rep
Title: Serum CXCL13 reflects local B-cell mediated inflammatory demyelinating peripheral neuropathy.
Volume: 9
Issue: 1
Pages: 16535
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Publication
16051865 | J:100096
First Author: Sun J
Year: 2005
Journal: J Virol
Title: Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury.
Volume: 79
Issue: 16
Pages: 10730-9
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Publication
19917700 | J:157510
First Author: Maroof A
Year: 2009
Journal: J Immunol
Title: Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen.
Volume: 183
Issue: 11
Pages: 7095-103
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Publication
19221395 | J:146797
First Author: Louvet C
Year: 2009
Journal: J Exp Med
Title: A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy.
Volume: 206
Issue: 3
Pages: 507-14
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Publication
24222350 | J:229067
First Author: Zhong J
Year: 2014
Journal: Diabetes
Title: T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance.
Volume: 63
Issue: 4
Pages: 1289-302
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Publication
9892625 | J:76908
First Author: Mandelbrot DA
Year: 1999
Journal: J Exp Med
Title: B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).
Volume: 189
Issue: 2
Pages: 435-40
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Publication
30068595 | J:265210
First Author: Cunningham CA
Year: 2018
Journal: J Immunol
Title: Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants.
Volume: 201
Issue: 6
Pages: 1627-1632
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Publication
21267999 | J:175433
First Author: Bar-On L
Year: 2011
Journal: Eur J Immunol
Title: Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation.
Volume: 41
Issue: 2
Pages: 291-8
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Publication
18607347 | J:138314
First Author: Duan B
Year: 2008
Journal: Lab Invest
Title: Intrafollicular location of marginal zone/CD1d(hi) B cells is associated with autoimmune pathology in a mouse model of lupus.
Volume: 88
Issue: 9
Pages: 1008-20
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Publication
12244135 | J:120409
First Author: Schneider H
Year: 2002
Journal: J Immunol
Title: Cutting edge: CTLA-4 (CD152) differentially regulates mitogen-activated protein kinases (extracellular signal-regulated kinase and c-Jun N-terminal kinase) in CD4+ T cells from receptor/ligand-deficient mice.
Volume: 169
Issue: 7
Pages: 3475-9
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Publication
16301639 | J:122138
First Author: Brinster C
Year: 2005
Journal: J Immunol
Title: Bone marrow-derived dendritic cells reverse the anergic state of CD4+CD25+ T cells without reversing their suppressive function.
Volume: 175
Issue: 11
Pages: 7332-40
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Publication
23108101 | J:193764
First Author: Seah SG
Year: 2013
Journal: J Leukoc Biol
Title: Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response.
Volume: 93
Issue: 1
Pages: 145-54
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Publication
10820290 | J:112278
First Author: Kinoshita K
Year: 2000
Journal: J Immunol
Title: Costimulation by B7-1 and B7-2 is required for autoimmune disease in MRL-Faslpr mice.
Volume: 164
Issue: 11
Pages: 6046-56
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Protein Coding Gene
MGP_CAROLIEiJ_G0020717 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022790 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022727 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_101773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_FVBNJ_G0022598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
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Protein Coding Gene
MGP_NODShiLtJ_G0022617 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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