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Search results 1 to 100 out of 881 for Cd8a

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
key_979873 | Cd8a
Type: gene
Organism: Not Specified
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Gene
403158 | CD8A
Type: gene
Organism: chicken
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Gene
428800 | CD8A
Type: gene
Organism: chicken
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Gene
677754 | cd8a
Type: gene
Organism: zebrafish
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Gene
925 | CD8A
Type: gene
Organism: human
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Gene
281060 | CD8A
Type: gene
Organism: cattle
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Gene
key_78455 | CD8A
Type: gene
Organism: cat, domestic
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Gene
24930 | Cd8a
Type: gene
Organism: rat
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Gene
403157 | CD8A
Type: gene
Organism: dog, domestic
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Gene
735755 | CD8A
Type: gene
Organism: chimpanzee
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Gene
698329 | CD8A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:88346 | Cd8a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
106699567 | LOC106699567
Type: gene
Organism: human
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Publication
- | J:177182
     
First Author: Koni PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Generation of a cre knock-in allele at the Cd8a locus
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Publication
9218488 | J:41712
First Author: Banan M
Year: 1997
Journal: J Biol Chem
Title: Interaction of the nuclear matrix-associated region (MAR)-binding proteins, SATB1 and CDP/Cux, with a MAR element (L2a) in an upstream regulatory region of the mouse CD8a gene.
Volume: 272
Issue: 29
Pages: 18440-52
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Protein
Q8K2M2
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Publication
15661911 | J:126027
First Author: Feik N
Year: 2005
Journal: J Immunol
Title: Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.
Volume: 174
Issue: 3
Pages: 1513-24
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Publication
22025728 | J:180248
First Author: Hassan H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.
Volume: 108
Issue: 45
Pages: 18330-5
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Publication
24681565 | J:209977
First Author: Boucheron N
Year: 2014
Journal: Nat Immunol
Title: CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.
Volume: 15
Issue: 5
Pages: 439-448
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Publication
12049716 | J:76799
First Author: Garefalaki A
Year: 2002
Journal: Immunity
Title: Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.
Volume: 16
Issue: 5
Pages: 635-47
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Publication
- | J:221492
     
First Author: Zeng M
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for alfalfa
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Publication
- | J:236677
     
First Author: Zeng M
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wenzhou
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Publication
16491076 | J:112614
First Author: Bilic I
Year: 2006
Journal: Nat Immunol
Title: Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.
Volume: 7
Issue: 4
Pages: 392-400
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Publication
35228603 | J:329130
First Author: Jin Y
Year: 2022
Journal: Sci Rep
Title: Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment.
Volume: 12
Issue: 1
Pages: 3278
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Publication
12049715 | J:113136
First Author: Ellmeier W
Year: 2002
Journal: Immunity
Title: Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.
Volume: 16
Issue: 5
Pages: 623-34
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Publication
11486276 | J:71668
First Author: Hardy CL
Year: 2001
Journal: Immunogenetics
Title: Identification of quantitative trait loci controlling activation of TRBV4 CD8+ T cells during murine gamma-herpesvirus-induced infectious mononucleosis.
Volume: 53
Issue: 5
Pages: 395-400
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Publication
9806636 | J:110530
First Author: Hostert A
Year: 1998
Journal: Immunity
Title: Hierarchical interactions of control elements determine CD8alpha gene expression in subsets of thymocytes and peripheral T cells.
Volume: 9
Issue: 4
Pages: 497-508
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Publication
10765562 | J:61415
First Author: Toth LA
Year: 1999
Journal: Behav Genet
Title: A quantitative genetic analysis of slow-wave sleep in influenza-infected CXB recombinant inbred mice.
Volume: 29
Issue: 5
Pages: 339-48
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Publication
20404101 | J:161237
First Author: Engel I
Year: 2010
Journal: J Exp Med
Title: Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection.
Volume: 207
Issue: 5
Pages: 1015-29
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Publication
22036949 | J:180236
First Author: Adoro S
Year: 2012
Journal: EMBO J
Title: Coreceptor gene imprinting governs thymocyte lineage fate.
Volume: 31
Issue: 2
Pages: 366-77
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Publication
20383150 | J:158947
First Author: Sakaguchi S
Year: 2010
Journal: Nat Immunol
Title: The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.
Volume: 11
Issue: 5
Pages: 442-8
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Publication
35523960 | J:331514
First Author: Shinzawa M
Year: 2022
Journal: Nat Immunol
Title: Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus.
Volume: 23
Issue: 5
Pages: 731-742
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Protein Coding Gene
MGP_CAROLIEiJ_G0028485 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030857 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030874 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022221 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029490 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3927298 | J:7962
First Author: Nakauchi H
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.
Volume: 82
Issue: 15
Pages: 5126-30
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Publication
3935316 | J:8124
First Author: Zamoyska R
Year: 1985
Journal: Cell
Title: Two Lyt-2 polypeptides arise from a single gene by alternative splicing patterns of mRNA.
Volume: 43
Issue: 1
Pages: 153-63
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Publication
3495785 | J:37454
First Author: Nakauchi H
Year: 1987
Journal: Nucleic Acids Res
Title: Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2.
Volume: 15
Issue: 10
Pages: 4337-47
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Publication
3267233 | J:9388
First Author: Youn HJ
Year: 1988
Journal: Immunogenetics
Title: Nucleotide sequence analysis of the C.AKR Lyt-2a gene: structural polymorphism in alleles encoding the Lyt-2.1 T-cell surface alloantigen.
Volume: 28
Issue: 5
Pages: 345-52
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Publication
3487583 | J:8328
First Author: Liaw CW
Year: 1986
Journal: J Immunol
Title: Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene.
Volume: 137
Issue: 3
Pages: 1037-43
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Publication
37459918 | J:354818
 
First Author: Golden JW
Year: 2023
Journal: Virus Res
Title: Induced protection from a CCHFV-M DNA vaccine requires CD8(+) T cells.
Volume: 334
Pages: 199173
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Publication
11390490 | J:123806
First Author: Moretto M
Year: 2001
Journal: J Immunol
Title: Gamma delta T cell-deficient mice have a down-regulated CD8+ T cell immune response against Encephalitozoon cuniculi infection.
Volume: 166
Issue: 12
Pages: 7389-97
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Publication
34433873 | J:314251
First Author: Strait AA
Year: 2021
Journal: Commun Biol
Title: Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma.
Volume: 4
Issue: 1
Pages: 1005
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Publication
16269570 | J:105682
First Author: Enoh VT
Year: 2006
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Differential effect of imipenem treatment on wild-type and NK cell-deficient CD8 knockout mice during acute intra-abdominal injury.
Volume: 290
Issue: 3
Pages: R685-93
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Publication
15067052 | J:89152
First Author: Ribas A
Year: 2004
Journal: J Immunol
Title: Enhanced tumor responses to dendritic cells in the absence of CD8-positive cells.
Volume: 172
Issue: 8
Pages: 4762-9
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Publication
17056525 | J:140528
First Author: Fragoso RC
Year: 2006
Journal: J Immunol
Title: A CD8/Lck transgene is able to drive thymocyte differentiation.
Volume: 177
Issue: 9
Pages: 6007-17
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Publication
11929984 | J:76066
First Author: Meehan TF
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: CD8(+) T cells are not necessary for 1 alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice.
Volume: 99
Issue: 8
Pages: 5557-60
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Publication
11535636 | J:71351
First Author: Zhang XL
Year: 2001
Journal: J Exp Med
Title: CD8 expression up to the double-positive CD3(low/intermediate) stage of thymic differentiation is sufficient for development of peripheral functional cytotoxic T lymphocytes.
Volume: 194
Issue: 5
Pages: 685-93
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Publication
12816997 | J:109845
First Author: Pearson T
Year: 2003
Journal: J Immunol
Title: Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice.
Volume: 171
Issue: 1
Pages: 185-95
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Publication
16920915 | J:139556
First Author: Ford MS
Year: 2006
Journal: J Immunol
Title: Double-negative T regulatory cells can develop outside the thymus and do not mature from CD8+ T cell precursors.
Volume: 177
Issue: 5
Pages: 2803-9
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Publication
8419174 | J:112993
First Author: Fung-Leung WP
Year: 1993
Journal: Eur J Immunol
Title: CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny.
Volume: 23
Issue: 1
Pages: 212-6
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Publication
18337581 | J:153304
First Author: Andrews NP
Year: 2008
Journal: J Virol
Title: Generation of antiviral major histocompatibility complex class I-restricted T cells in the absence of CD8 coreceptors.
Volume: 82
Issue: 10
Pages: 4697-705
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Publication
32881103 | J:305403
First Author: Myles IA
Year: 2021
Journal: J Leukoc Biol
Title: Frontline Science: Breast milk confers passive cellular immunity via CD8-dependent mechanisms.
Volume: 109
Issue: 4
Pages: 709-715
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Publication
8453666 | J:112991
First Author: Olsson T
Year: 1993
Journal: Cell
Title: CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule.
Volume: 72
Issue: 5
Pages: 715-27
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Publication
9673288 | J:48826
First Author: Huber M
Year: 1998
Journal: Infect Immun
Title: Effective and long-lasting immunity against the parasite Leishmania major in CD8-deficient mice.
Volume: 66
Issue: 8
Pages: 3968-70
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Publication
9551910 | J:45177
First Author: Grdic D
Year: 1998
Journal: J Immunol
Title: Lack of local suppression in orally tolerant CD8-deficient mice reveals a critical regulatory role of CD8+ T cells in the normal gut mucosa.
Volume: 160
Issue: 2
Pages: 754-62
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Publication
16552068 | J:107387
First Author: Marquis M
Year: 2006
Journal: Infect Immun
Title: CD8+ T cells but not polymorphonuclear leukocytes are required to limit chronic oral carriage of Candida albicans in transgenic mice expressing human immunodeficiency virus type 1.
Volume: 74
Issue: 4
Pages: 2382-91
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Publication
8223860 | J:113044
First Author: Fung-Leung WP
Year: 1993
Journal: Eur J Immunol
Title: The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes.
Volume: 23
Issue: 11
Pages: 2834-40
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Publication
30674678 | J:271178
First Author: Coque E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cytotoxic CD8+ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons.
Volume: 116
Issue: 6
Pages: 2312-2317
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Publication
38807587 | J:352313
 
First Author: Salazar FC
Year: 2024
Journal: Front Immunol
Title: CD8 T cells are dispensable for experimental autoimmune prostatitis induction and chronic pelvic pain development.
Volume: 15
Pages: 1387142
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Publication
36330507 | J:337609
 
First Author: John J
Year: 2022
Journal: Front Immunol
Title: Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumors.
Volume: 13
Pages: 992630
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Publication
36429085 | J:337605
 
First Author: Mooslechner AA
Year: 2022
Journal: Cells
Title: Low-Dose rIL-15 Protects from Nephrotoxic Serum Nephritis via CD8(+) T Cells.
Volume: 11
Issue: 22
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Publication
31322426 | J:279025
First Author: Ilatovskaya DV
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: CD8+ T-cells negatively regulate inflammation post-myocardial infarction.
Volume: 317
Issue: 3
Pages: H581-H596
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Publication
11336693 | J:132432
First Author: Bosselut R
Year: 2001
Journal: Immunity
Title: Strength of signaling by CD4 and CD8 coreceptor tails determines the number but not the lineage direction of positively selected thymocytes.
Volume: 14
Issue: 4
Pages: 483-94
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Publication
1589800 | J:1033
First Author: Koh DR
Year: 1992
Journal: Science
Title: Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice.
Volume: 256
Issue: 5060
Pages: 1210-3
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Publication
9197272 | J:82165
First Author: Tanchot C
Year: 1997
Journal: Science
Title: Differential requirements for survival and proliferation of CD8 naïve or memory T cells.
Volume: 276
Issue: 5321
Pages: 2057-62
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Publication
19164596 | J:148431
First Author: Fujii S
Year: 2009
Journal: Blood
Title: Antigen mRNA-transfected, allogeneic fibroblasts loaded with NKT-cell ligand confer antitumor immunity.
Volume: 113
Issue: 18
Pages: 4262-72
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Publication
18465769 | J:136196
First Author: Riddle DS
Year: 2008
Journal: Eur J Immunol
Title: Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II.
Volume: 38
Issue: 6
Pages: 1511-21
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Publication
11157050 | J:124426
First Author: Ciurea A
Year: 2001
Journal: J Exp Med
Title: Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants.
Volume: 193
Issue: 3
Pages: 297-305
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Publication
19158156 | J:150554
First Author: Stromberg PE
Year: 2009
Journal: FASEB J
Title: CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis.
Volume: 23
Issue: 6
Pages: 1817-25
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Publication
15258576 | J:91610
First Author: Miyahara N
Year: 2004
Journal: Nat Med
Title: Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness.
Volume: 10
Issue: 8
Pages: 865-9
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Publication
15470028 | J:93713
First Author: Swanson KA
Year: 2004
Journal: J Immunol
Title: Flt3-ligand, IL-4, GM-CSF, and adherence-mediated isolation of murine lung dendritic cells: assessment of isolation technique on phenotype and function.
Volume: 173
Issue: 8
Pages: 4875-81
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Publication
18426985 | J:136299
First Author: Okamoto M
Year: 2008
Journal: J Exp Med
Title: Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.
Volume: 205
Issue: 5
Pages: 1087-97
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Publication
23658704 | J:200538
First Author: Zhang JM
Year: 2013
Journal: PLoS One
Title: Knockout of CD8 delays reendothelialization and accelerates neointima formation in injured arteries of mouse via TNF-α inhibiting the endothelial cells migration.
Volume: 8
Issue: 5
Pages: e62001
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Publication
1460424 | J:110723
First Author: Wallace VA
Year: 1992
Journal: J Exp Med
Title: CD45RA and CD45RBhigh expression induced by thymic selection events.
Volume: 176
Issue: 6
Pages: 1657-63
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Publication
21629771 | J:172575
First Author: Růžek D
Year: 2011
Journal: PLoS One
Title: Breakdown of the blood-brain barrier during tick-borne encephalitis in mice is not dependent on CD8+ T-cells.
Volume: 6
Issue: 5
Pages: e20472
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Publication
7561076 | J:29580
First Author: Bachmann MF
Year: 1995
Journal: J Immunol
Title: T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.
Volume: 155
Issue: 8
Pages: 3727-33
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Publication
32554515 | J:355136
First Author: Rao G
Year: 2020
Journal: Clin Cancer Res
Title: Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells.
Volume: 26
Issue: 17
Pages: 4699-4712
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Publication
15634879 | J:95843
First Author: Maile R
Year: 2005
Journal: J Immunol
Title: Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo.
Volume: 174
Issue: 2
Pages: 619-27
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Publication
9806635 | J:50624
First Author: Ellmeier W
Year: 1998
Journal: Immunity
Title: Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.
Volume: 9
Issue: 4
Pages: 485-96
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Publication
16237050 | J:119364
First Author: Chandele A
Year: 2005
Journal: J Immunol
Title: Cutting edge: memory CD8 T cell maturation occurs independently of CD8alphaalpha.
Volume: 175
Issue: 9
Pages: 5619-23
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Publication
2783886 | J:9614
First Author: Ishizaka ST
Year: 1989
Journal: Cancer Res
Title: Genetic control of resistance to 3-methylcholanthrene-induced T-cell lymphoma in mice.
Volume: 49
Issue: 5
Pages: 1214-9
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Publication
25284152 | J:217551
First Author: Stepanek O
Year: 2014
Journal: Cell
Title: Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance.
Volume: 159
Issue: 2
Pages: 333-45
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Publication
15749886 | J:97692
First Author: Attinger A
Year: 2005
Journal: J Immunol
Title: Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule.
Volume: 174
Issue: 6
Pages: 3501-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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