|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 5372 for Cdh1

<< First    < Previous  |  Next >    Last >>
1.133s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
999 | CDH1
Type: gene
Organism: human
•
•
•
•
•
Gene
282637 | CDH1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
415860 | CDH1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
114424 | cdh1
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
704387 | CDH1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
779546 | cdh1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
83502 | Cdh1
Type: gene
Organism: rat
•
•
•
•
•
Gene
442858 | CDH1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
468009 | CDH1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Protein Domain
IPR030049 | CDH1
Type: Family
Description: E-cadherin (epithelial-cadherin), also known as cadherin-1 (CADH1), is a calcium-dependent adherens junction protein that forms homophilic intercellular contacts in epithelial cells []. It is essential for embryonic development in mice []. It cooperates with N-cadherin during lensdevelopment [].
•
•
•
•
•
Protein Coding Gene
MGI:88354 | Cdh1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
8058792 | J:19904
First Author: Larue L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: E-cadherin null mutant embryos fail to form a trophectoderm epithelium.
Volume: 91
Issue: 17
Pages: 8263-7
•
•
•
•
•
Publication
18996109 | J:145191
First Author: Pontoriero GF
Year: 2009
Journal: Dev Biol
Title: Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.
Volume: 326
Issue: 2
Pages: 403-17
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7414383
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Areas of expression include the outer compartment.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3821059
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825677
Age: embryonic day 14.5
Image: Additional file 4 Cdh1
Specimen Label: Additional file 4 Cdh1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7414383
Age: embryonic day 12.5
Image: 1c E12.5 CDH1
Specimen Label: 1c E12.5 CDH1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7414383
Age: embryonic day 13.5
Image: 1c E13.5 CDH1
Specimen Label: 1c E13.5 CDH1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7414383
Age: embryonic day 14.5
Image: 1c E14.5 CDH1
Note: Areas of expression include the outer compartment of the developing organ of Corti.
Specimen Label: 1c E14.5 CDH1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5775351
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7414383
Age: embryonic day 15.5
Image: 1c E15.5 CDH1
Note: Areas of expression include the outer compartment of the developing organ of Corti.
Specimen Label: 1c E15.5 CDH1
Detected: true
Specimen Num: 4
•
•
•
•
•
Protein
P09803
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
•
•
•
•
•
Protein
Q4KML8
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
•
•
•
•
•
Protein
A0A0R4IZW5
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
•
•
•
•
•
Publication
25079037 | -
 
First Author: Chen A
Year: 2014
Journal: BMC Cancer
Title: E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition.
Volume: 14
Pages: 552
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760020
Pattern: Widespread
Stage: TS20
Assay Id: MGI:7414373
Age: embryonic day 12.5
Image: 1c E12.5 CDH1
Note: Expression is seen in the prosensory epithelium in the floor of the cochlear duct.
Specimen Label: 1c E12.5 CDH1
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760021
Pattern: Widespread
Stage: TS21
Assay Id: MGI:7414373
Age: embryonic day 13.5
Image: 1c E13.5 CDH1
Note: Expression is seen in the prosensory epithelium in the floor of the cochlear duct.
Specimen Label: 1c E13.5 CDH1
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:7414373
Age: embryonic day 14.5
Image: 1c E14.5 CDH1
Note: Expression is seen in the prosensory epithelium. Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E14.5 CDH1
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760023
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:7414373
Age: embryonic day 15.5
Image: 1c E15.5 CDH1
Note: Expression is seen in the prosensory epithelium. Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E15.5 CDH1
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is weaker than in the organ of Corti.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is strongly upregulated in the inner (medial) region of the developing organ of Corti; it is excluded from the outer (lateral) region.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7414254
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3538426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7414373
Age: embryonic day 18.5
Image: 1c E18.5 CDH1
Note: Expression is weaker than in the organ of Corti.
Specimen Label: 1c E18.5 CDH1
Detected: true
Specimen Num: 15
•
•
•
•
•
Publication
22152476 | J:317065
First Author: Wan L
Year: 2011
Journal: Mol Cell
Title: Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
Volume: 44
Issue: 5
Pages: 721-33
•
•
•
•
•
Publication
20652949 | J:163273
First Author: Stemmler MP
Year: 2010
Journal: Dev Dyn
Title: A Cdh1HA knock-in allele rescues the Cdh1-/- phenotype but shows essential Cdh1 function during placentation.
Volume: 239
Issue: 9
Pages: 2330-44
•
•
•
•
•
Publication
17035642 | J:117360
First Author: Tokuda M
Year: 2007
Journal: Biol Reprod
Title: CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes.
Volume: 76
Issue: 1
Pages: 130-41
•
•
•
•
•
Publication
33211830 | J:298844
 
First Author: Pascal LE
Year: 2021
Journal: Endocrinology
Title: Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity.
Volume: 162
Issue: 1
•
•
•
•
•
HT Experiment
E-GEOD-54234 | CDH1 knockout in mice
Series Id: GSE54234
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
30332649 | J:270695
First Author: An Y
Year: 2018
Journal: Cell Rep
Title: Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast.
Volume: 25
Issue: 3
Pages: 702-714.e6
•
•
•
•
•
Publication
31964702 | J:287966
 
First Author: Wang Y
Year: 2020
Journal: J Cell Sci
Title: CENP-T regulates both the G2/M transition and anaphase entry by acting through CDH1 in meiotic oocytes.
Volume: 133
Issue: 3
•
•
•
•
•
Publication
24301385 | J:206141
 
First Author: Eguren M
Year: 2013
Journal: Nat Commun
Title: The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors.
Volume: 4
Pages: 2880
•
•
•
•
•
Publication
22378759 | J:185830
First Author: Reardon SN
Year: 2012
Journal: Biol Reprod
Title: CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus.
Volume: 86
Issue: 5
Pages: 141, 1-10
•
•
•
•
•
Publication
23740945 | J:202051
First Author: Lindberg ME
Year: 2013
Journal: Biol Reprod
Title: Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus.
Volume: 89
Issue: 1
Pages: 8
•
•
•
•
•
Publication
35729193 | J:326127
First Author: Cuadrado M
Year: 2022
Journal: Sci Rep
Title: Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts.
Volume: 12
Issue: 1
Pages: 10489
•
•
•
•
•
Publication
20530197 | J:162785
First Author: Naoe H
Year: 2010
Journal: Mol Cell Biol
Title: The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Volume: 30
Issue: 16
Pages: 3994-4005
•
•
•
•
•
Publication
24998851 | J:221256
First Author: Stodden GR
Year: 2015
Journal: Oncogene
Title: Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment.
Volume: 34
Issue: 19
Pages: 2471-82
•
•
•
•
•
Publication
28065642 | J:316682
First Author: An J
Year: 2017
Journal: Stem Cell Reports
Title: Mesenchymal to Epithelial Transition Mediated by CDH1 Promotes Spontaneous Reprogramming of Male Germline Stem Cells to Pluripotency.
Volume: 8
Issue: 2
Pages: 446-459
•
•
•
•
•
Publication
31930396 | J:298073
First Author: Shi M
Year: 2020
Journal: Biol Reprod
Title: Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis.
Volume: 102
Issue: 5
Pages: 1055-1064
•
•
•
•
•
Publication
30168144 | J:273794
First Author: Kinoshita H
Year: 2019
Journal: J Pathol
Title: Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.
Volume: 247
Issue: 1
Pages: 35-47
•
•
•
•
•
Publication
19160489 | J:138545
First Author: Li M
Year: 2008
Journal: Nat Cell Biol
Title: The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory.
Volume: 10
Issue: 9
Pages: 1083-9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189933
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cdh1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189933
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cdh1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cdh1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cdh1
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189933
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cdh1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189933
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cdh1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6169465
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189933
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cdh1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1935063
Assay Type: Immunohistochemistry
Annotation Date: 2001-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:2135569
Age: embryonic day 13.5
Image: 3F/G
Note: Two Cdh1 positive columns of expression are detected in the mesencephalic roof plate.
Specimen Label: 3F/G
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1339624
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6867049
Age: embryonic day 3.0
Note: Double staining revealed co-localization of Tjp2 and Cdh1 in the apicolateral junctional complex.
Specimen Label: 4A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1935063
Assay Type: Immunohistochemistry
Annotation Date: 2001-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2135569
Age: embryonic day 12.5
Image: 3C/D/E
Note: Cdh1 positive fibers extend to the marginal zone and migrated upwards to the ventral midline.
Specimen Label: 3C/D/E
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6194264
Assay Type: Western blot
Annotation Date: 2022-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7328801
Age: postnatal day 12
Specimen Label: Cdh1 cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1339624
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6867049
Age: embryonic day 3.5
Note: Cdh1 staining was localized in the apicolateral junctional complex, but in early blastocysts Tjp2 is apical to and distinct from Cdh1.
Specimen Label: 4B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6448438
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6448447
Age: embryonic day 8.5
Note: Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
Specimen Label: 2H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6448438
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6448447
Age: embryonic day 8.5
Note: Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
Specimen Label: 2I
Detected: true
Specimen Num: 5
•
•
•
•
•
Publication
31420536 | J:279397
First Author: Han T
Year: 2019
Journal: Nat Commun
Title: Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis.
Volume: 10
Issue: 1
Pages: 3716
•
•
•
•
•
Publication
27126000 | J:302804
First Author: Shao R
Year: 2016
Journal: Cell Res
Title: Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.
Volume: 26
Issue: 6
Pages: 699-712
•
•
•
•
•
Publication
23206702 | J:193869
First Author: Naoe H
Year: 2013
Journal: Biochem Biophys Res Commun
Title: The APC/C activator Cdh1 regulates the G2/M transition during differentiation of placental trophoblast stem cells.
Volume: 430
Issue: 2
Pages: 757-62
•
•
•
•
•
Publication
24100295 | J:201983
First Author: Listovsky T
Year: 2013
Journal: J Cell Biol
Title: Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.
Volume: 203
Issue: 1
Pages: 87-100
•
•
•
•
•
Publication
14716021 | J:90373
First Author: Konishi Y
Year: 2004
Journal: Science
Title: Cdh1-APC controls axonal growth and patterning in the mammalian brain.
Volume: 303
Issue: 5660
Pages: 1026-30
•
•
•
•
•
Publication
22479204 | J:183847
First Author: Bedzhov I
Year: 2012
Journal: PLoS Genet
Title: Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin.
Volume: 8
Issue: 3
Pages: e1002609
•
•
•
•
•
Publication
17692806 | J:124321
First Author: Ceteci F
Year: 2007
Journal: Cancer Cell
Title: Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer.
Volume: 12
Issue: 2
Pages: 145-59
•
•
•
•
•
Publication
28650484 | J:297039
First Author: Kas SM
Year: 2017
Journal: Nat Genet
Title: Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.
Volume: 49
Issue: 8
Pages: 1219-1230
•
•
•
•
•
Publication
25449798 | J:320387
First Author: Schneider MR
Year: 2015
Journal: Bioessays
Title: E-cadherin's role in development, tissue homeostasis and disease: Insights from mouse models: Tissue-specific inactivation of the adhesion protein E-cadherin in mice reveals its functions in health and disease.
Volume: 37
Issue: 3
Pages: 294-304
•
•
•
•
•
Publication
37225711 | J:341600
First Author: Alvizi L
Year: 2023
Journal: Nat Commun
Title: Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction.
Volume: 14
Issue: 1
Pages: 2868
•
•
•
•
•
Publication
25652130 | J:230561
First Author: Alotaibi H
Year: 2015
Journal: Biochim Biophys Acta
Title: Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition.
Volume: 1849
Issue: 6
Pages: 731-42
•
•
•
•
•
Publication
18519590 | J:137938
First Author: Herranz N
Year: 2008
Journal: Mol Cell Biol
Title: Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.
Volume: 28
Issue: 15
Pages: 4772-81
•
•
•
•
•
Publication
28760854 | J:245682
First Author: Till JE
Year: 2017
Journal: Cancer Res
Title: Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis in Mice That Can Be Attenuated by E-Cadherin Expression.
Volume: 77
Issue: 19
Pages: 5349-5359
•
•
•
•
•
Publication
21186356 | J:170573
First Author: Fu AK
Year: 2011
Journal: Nat Neurosci
Title: APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity.
Volume: 14
Issue: 2
Pages: 181-9
•
•
•
•
•
Publication
19223545 | J:146609
First Author: Humar B
Year: 2009
Journal: Cancer Res
Title: E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man.
Volume: 69
Issue: 5
Pages: 2050-6
•
•
•
•
•
Publication
29917067 | J:313222
First Author: Ihara S
Year: 2018
Journal: J Crohns Colitis
Title: Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease.
Volume: 12
Issue: 10
Pages: 1219-1231
•
•
•
•
•
Publication
19726720 | J:155503
First Author: Van den Bossche J
Year: 2009
Journal: Blood
Title: Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes.
Volume: 114
Issue: 21
Pages: 4664-74
•
•
•
•
•
Publication
21179475 | J:168992
First Author: Schneider MR
Year: 2010
Journal: PLoS One
Title: A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.
Volume: 5
Issue: 12
Pages: e14325
•
•
•
•
•
Publication
25588837 | J:223226
First Author: Krawchuk D
Year: 2015
Journal: J Cell Sci
Title: Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.
Volume: 128
Issue: 5
Pages: 1011-22
•
•
•
•
•
Publication
21865403 | J:262393
First Author: Shimada S
Year: 2012
Journal: Gut
Title: Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer.
Volume: 61
Issue: 3
Pages: 344-53
•
•
•
•
•
Publication
25233932 | J:216984
First Author: Andl T
Year: 2014
Journal: Carcinogenesis
Title: Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma.
Volume: 35
Issue: 11
Pages: 2602-10
•
•
•
•
•
Publication
12655059 | J:82758
First Author: Chabes AL
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis.
Volume: 100
Issue: 7
Pages: 3925-9
•
•
•
•
•
Publication
15029244 | J:90113
First Author: Listovsky T
Year: 2004
Journal: EMBO J
Title: Mammalian Cdh1/Fzr mediates its own degradation.
Volume: 23
Issue: 7
Pages: 1619-26
•
•
•
•
•
Publication
31771969 | J:284071
First Author: Zhang H
Year: 2020
Journal: Cancer Discov
Title: Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.
Volume: 10
Issue: 2
Pages: 288-305
•
•
•
•
•
Publication
31217166 | J:279036
First Author: Yoon C
Year: 2019
Journal: Mol Cancer Res
Title: KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem-Like Cells and Promotes Metastasis.
Volume: 17
Issue: 9
Pages: 1945-1957
•
•
•
•
•
Publication
33277378 | J:311886
 
First Author: Varghese PC
Year: 2021
Journal: J Cell Sci
Title: Histone chaperone APLF level dictates the implantation of mouse embryos.
Volume: 134
Issue: 1
•
•
•
•
•
Publication
18452489 | J:137610
First Author: Nimura M
Year: 2008
Journal: Congenit Anom (Kyoto)
Title: Adrenocorticotropic hormone affects nonapoptotic cell death of undifferentiated germ cells in the fetal mouse testis: in vivo study by exo utero transplantation of corticotropic tumor cells into embryos.
Volume: 48
Issue: 2
Pages: 81-6
•
•
•
•
•
Publication
27340177 | J:233376
First Author: Annunziato S
Year: 2016
Journal: Genes Dev
Title: Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.
Volume: 30
Issue: 12
Pages: 1470-80
•
•
•
•
•
Publication
17327688 | J:122711
First Author: Umesako S
Year: 2007
Journal: J Radiat Res
Title: Distinct pattern of allelic loss and inactivation of cadherin 1 and 5 genes in mammary carcinomas arising in p53(+/-) mice.
Volume: 48
Issue: 2
Pages: 143-52
•
•
•
•
•
Publication
25651564 | J:280116
First Author: Su H
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: MAD2B contributes to podocyte injury of diabetic nephropathy via inducing cyclin B1 and Skp2 accumulation.
Volume: 308
Issue: 7
Pages: F728-36
•
•
•
•
•
Publication
24503032 | J:207607
First Author: Keil KP
Year: 2014
Journal: Dev Biol
Title: DNA methylation of E-cadherin is a priming mechanism for prostate development.
Volume: 387
Issue: 2
Pages: 142-53
•
•
•
•
•
Publication
31658259 | J:280691
First Author: Olson A
Year: 2019
Journal: PLoS Genet
Title: The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.
Volume: 15
Issue: 10
Pages: e1008451
•
•
•
•
•
Publication
17215516 | J:124023
First Author: Wu G
Year: 2007
Journal: Mol Biol Cell
Title: The anaphase-promoting complex coordinates initiation of lens differentiation.
Volume: 18
Issue: 3
Pages: 1018-29
•
•
•
•
•
Publication
17278136 | J:137001
First Author: Akins MR
Year: 2007
Journal: J Comp Neurol
Title: Cadherin expression in the developing mouse olfactory system.
Volume: 501
Issue: 4
Pages: 483-97
•
•
•
•
•
Publication
33735101 | J:301645
 
First Author: Cleal L
Year: 2021
Journal: Dis Model Mech
Title: Resolving the heterogeneity of diaphragmatic mesenchyme: a novel mouse model of congenital diaphragmatic hernia.
Volume: 14
Issue: 1
•
•
•
•
•
Publication
24784840 | J:212549
First Author: Park JW
Year: 2014
Journal: Mol Cancer Res
Title: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.
Volume: 12
Issue: 8
Pages: 1088-99
•
•
•
•
•
Publication
22173065 | J:180791
First Author: Saravanamuthu SS
Year: 2012
Journal: Dev Biol
Title: Conditional ablation of the Notch2 receptor in the ocular lens.
Volume: 362
Issue: 2
Pages: 219-29
•
•
•
•
•
Publication
31100714 | J:285721
First Author: Piprek RP
Year: 2019
Journal: Reproduction
Title: Tissue-specific knockout of E-cadherin (Cdh1) in developing mouse gonads causes germ cells loss.
Volume: 158
Issue: 2
Pages: 147-157
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5317435
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6435784
Age: postnatal adult
Image: S3C/C'
Note: Co-expression with Cdh1 in liver.
Specimen Label: S3C/C'
Detected: true
Specimen Num: 2
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom